Distinct roles of CaMKII and PKA in regulation of firing patterns and K+ currents in Drosophila neurons

Journal of Neurophysiology

Volumn 85, Issue 4, 2001, Pages 1384-1394

  Yao, Wei Dong ^a,b   Wu, Chun Fang ^a  

^a UNIVERSITY OF IOWA   (United States)

^b DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN DEPENDENT KINASE; POTASSIUM CHANNEL; PROTEIN KINASE (CALCIUM,CALMODULIN) II;

ACTION POTENTIAL; ANIMAL CELL; ARTICLE; DROSOPHILA; ENZYME INHIBITION; ENZYME SUBUNIT; LEARNING; MEMORY; NERVE CELL EXCITABILITY; NERVE CELL PLASTICITY; NERVE CONDUCTION; NONHUMAN; POTASSIUM CURRENT; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SPIKE; SYNAPTIC TRANSMISSION;

EID: 0035065673     PISSN: 00223077     EISSN: None     Source Type: Journal    
DOI: 10.1152/jn.2001.85.4.1384     Document Type: Article

References (79)

1. Learning and memory in Drosophila, studied with mutants
2. Learning in normal and mutant Drosophila larvae
3. Structural changes accompanying memory storage
4. + current in a subset of neurons
5. A synaptic model of memory: Long-term potentiation in the hippocampus
6. Morphological plasticity of motor axons in Drosophila mutants with altered excitability
7. A family of putative potassium channel genes in Drosophila
8. 2+/calmodulin-dependent kinase II alpha-subunit mutation
9. Defect in cyclic AMP phosphodiesterase due to the dunce mutation of learning in Drosophila melanogaster
10. Presynaptic facilitation revisited: State and time dependence
11. Molecular genetic analysis of synaptic plasticity, activity-dependent neural development, learning and memory in the mammalian brain
12. Activity-dependent plasticity in the visual systems of frogs and fish
13. Physiology and biochemistry of Drosophila learning mutants
14. Outward currents in Drosophila larval neurons: dunce lacks a maintained outward current component downregulated by cAMP
15. + channel in Drosophila larval muscle is persistently activated in dunce
16. Primary structure and functional expression of a cyclic nucleotide-activated channel from olfactory neurons
17. + channel inactivation gating by the cAMP-dependent protein kinase
18. cAMP-dependent protein kinase and the disruption of learning in transgenic flies
19. dunce, a mutant of Drosophila deficient in learning
20. Three Drosophila mutations that block associative learning also affect habituation and sensitization
21. Alteration of non-associative conditioning of an identified escape circuit in Drosophila memory mutants
22. Genetic dissection of functional contributions of specific potassium channel subunits in habituation of an escape circuit in Drosophila
23. Emerging principles governing the operation of neural networks
24. Defective learning in mutants of the Drosophila gene for a regulatory subunit of cAMP-dependent protein kinase
25. Inhibition of calcium/calmodulin-dependent protein kinase in Drosophila disrupts behavioral plasticity
26. + channel subunit Eag similarly affect plasticity in Drosophila
27. Modulation of neural networks for behavior
28. Drosophila mushroom body mutants are deficient in olfactory learning
29. A genetic test of the effects of mutations in PKA on mossy fiber LTP and its relation to spatial and contextual learning
30. The period of susceptibility to the physiological effects of unilateral eye closure in kittens
31. The role of the divergent amino and carboxyl domains on the inactivation properties of potassium channels derived from the Shaker gene of Drosophila
32. Properties of the larval neuromuscular junction in Drosophila melanogaster
33. Multiple products of Drosophila Shaker gene may contribute to potassium channel diversity
34. The postsynaptic density at glutamatergic synapses
35. 2+/calmodulin-responsive adenylyl cyclase
36. Effects of a conditional Drosophila PKA mutant on olfactory learning and memory
37. 2+/calmodulin responsiveness in adenylate cyclase of rutabaga, a Drosophila learning mutant
38. An essential role for post synaptic calmodulin and protein kinase activity in long-term potentiation
39. Inhibition of postsynaptic PKC or CaMKII blocks induction but not expression of LTP
40. Memory from the dynamics of intrinsic membrane currents
41. Control of memory formation through regulated expression of a CaMKII transgene
42. Cellular mechanisms underlying cholinergic and noradrenergic modulation of neuronal firing mode in the cat and gunia pig dorsal lateral geniculate nucleus
43. Protein kinases in the brain
44. + currents: A role in shaping the photoreceptor potential
45. Shaker encodes a family of putative potassium channel proteins in the nerve system of Drosophila
46. Conditioned behavior in Drosophila melanogaster
47. Neuronal polymorphism among natural alleles of a cGMP-dependent kinase gene, foraging, in Drosophila
48. + channels
49. Expression of ion channels and mutational effects in giant Drosophila neurons differentiated from cell division arrested embryonic neuroblasts
50. Ionic channels in cultured Drosophila neurons
51. Genetic modification of potassium channels in Drosophila Shaker mutants
52. Multiple potassium-channel components are produced by alternative splicing at the Shaker locus in Drosophila
53. Conditioned responses in courtship behavior of normal and mutant Drosophila
54. Deficient hippocampal long-term potentiation in a calcium-calmodulin kinase II mutant mice
55. Impaired spatial learning in α-calcium-calmodulin kinase II mutant mice
56. Unmasking of a novel potassium current in Drosophila by a mutation and drugs
57. Associative learning of Drosophila melanogaster
58. 2+/calmodulin-dependent protein kinase II inhibitor Kn-93 reduces dopamine contents in PC12h cells
59. Four cDNA clones from the Sh locus of Drosophila induce kinetically distinct A-type potassium currents in Xenopus oocytes
60. 2+/calmodulin-dependent protein kinase II
61. Genetic analysis of Drosophila neurons: Shal, Shaw and Shab encode most embryonic potassium currents
62. The major delayed rectifier in both Drosophila neurons and muscle is encoded by Shab
63. A return to genetic dissection of memory in Drosophila
64. Activity changes the intrinsic properties of cultured neurons
65. Selective regulation of current densities underlies spontaneous changes in the activity of cultured neurons
66. Concomitant alterations of physiological and developmental plasticity in Drosophila CaM kinase II-inhibited synapses
67. Neurogenetic studies of ion channels in Drosophila
68. Voltage clamp analysis of membrane currents in larval muscle fibers of Drosophila: Alteration of potassium currents in Shaker mutants
69. Giant Drosophila neurons differentiated from cytokinesis-arrested embryonic neuroblasts
70. A new paradigm for operant conditioning of Drosophila melanogaster
71. + currents in Drosophila neurons
72. + currents by calcium/calmodulin-dependent protein kinase II in Drosophila embryonic neurons
73. + channels in cultured Drosophila neurons derived from Sh cDNA transformants: Distinct properties, distribution, and turn over
74. Alterations in frequency coding and activity dependence of excitability in cultured neurons of Drosophila memory mutants
75. Synaptic plasticity in Drosophila memory and hyperexcitable mutants: Role of cAMP cascade
76. Altered synaptic plasticity in Drosophila memory mutants with a defective cyclic AMP cascade
77. Differential modulation of potassium currents by cAMP and its long-term and short-term effects: dunce and rutabaga mutants of Drosophila