A highly conserved amino-terminal region of Sonic Hedgehog is required for the formation of its freely diffusible multimeric form

Journal of Biological Chemistry

Volumn 281, Issue 7, 2006, Pages 4087-4093

  Goetz, John A ^a   Singh, Samer ^a   Suber, Liza M ^d   Kull, F Jon ^c   Robbins, David J ^a,b  

^a DARTMOUTH MEDICAL SCHOOL   (United States)

^b DARTMOUTH HITCHCOCK MEDICAL CENTER   (United States)

^c Dartmouth College   (United States)

^d UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL MEMBRANES; CHOLESTEROL; CRYSTAL STRUCTURE; DIFFUSION; HYDROPHOBICITY; PROTEINS; SYNTHESIS (CHEMICAL);

MORPHOGENS; MULTIMERIC FORM; PALMITATE; PALMITOYLATION;

MOLECULAR BIOLOGY;

MUTANT PROTEIN; POLYMER; RECOMBINANT PROTEIN; SONIC HEDGEHOG PROTEIN; PALMITIC ACID; SHH PROTEIN, HUMAN; TRANSACTIVATOR PROTEIN;

AMINO TERMINAL SEQUENCE; ARTICLE; CONTROLLED STUDY; CRYSTAL STRUCTURE; HUMAN; HUMAN CELL; PALMITOYLATION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; PROTEIN STRUCTURE; AMINO ACID SEQUENCE; CHEMISTRY; CRYSTALLIZATION; DIFFUSION; METABOLISM; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; PHYSIOLOGY;

ERINACEIDAE;

AMINO ACID SEQUENCE; CONSERVED SEQUENCE; CRYSTALLIZATION; DIFFUSION; HEDGEHOG PROTEINS; MOLECULAR SEQUENCE DATA; PALMITIC ACID; TRANS-ACTIVATORS;

EID: 33645228803     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M511427200     Document Type: Article

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