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Volumn 154, Issue 2 SUPPL., 1996, Pages

Molecular mechanisms of immunosuppression and anti-inflammatory activities by glucocorticoids

Author keywords

[No Author keywords available]

Indexed keywords

DEXAMETHASONE; GLUCOCORTICOID RECEPTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MESSENGER RNA; PHORBOL 13 ACETATE 12 MYRISTATE; RECOMBINANT TUMOR NECROSIS FACTOR ALPHA; TRANSCRIPTION FACTOR AP 1;

EID: 0029737089     PISSN: 1073449X     EISSN: None     Source Type: Journal    
DOI: 10.1164/ajrccm/154.2_pt_2.s11     Document Type: Review
Times cited : (69)

References (35)
  • 1
    • 0018657510 scopus 로고
    • Mechanisms of glucocorticoid action on immune process
    • Parillo, J. E., and A. S. Fauci. 1979. Mechanisms of glucocorticoid action on immune process. Ann. Rev. Pharmacol. Toxicol. 19:179-209.
    • (1979) Ann. Rev. Pharmacol. Toxicol. , vol.19 , pp. 179-209
    • Parillo, J.E.1    Fauci, A.S.2
  • 2
    • 0002548204 scopus 로고
    • R. P. Scheimer, H. N. Claman, and A. L. Oronsky, editors. Academic Press, San Diego.
    • Cohen, J. J. 1989. In R. P. Scheimer, H. N. Claman, and A. L. Oronsky, editors. Anti-inflammatory Steroid Action. Basic and Clinical Aspects. Academic Press, San Diego. 111-131.
    • (1989) Anti-inflammatory Steroid Action. Basic and Clinical Aspects , pp. 111-131
    • Cohen, J.J.1
  • 3
    • 0002669303 scopus 로고
    • Proteinases and matrix degradation
    • W. N. Kelly, E. Harris, Jr., S. Ruddy, and C. B. Sledge, editors. W. B. Saunders, Philadelphia.
    • Werb, Z. 1989. Proteinases and matrix degradation. In W. N. Kelly, E. Harris, Jr., S. Ruddy, and C. B. Sledge, editors. Textbook of Rheumatology. W. B. Saunders, Philadelphia. 300-321.
    • (1989) Textbook of Rheumatology , pp. 300-321
    • Werb, Z.1
  • 4
    • 0027377816 scopus 로고
    • An overview of glucocorticoid anti-inflammatory actions
    • Schleimer, R. P. 1993. An overview of glucocorticoid anti-inflammatory actions. Eur. J. Clin. Pharmacol. 45:3-7.
    • (1993) Eur. J. Clin. Pharmacol. , vol.45 , pp. 3-7
    • Schleimer, R.P.1
  • 5
    • 0028527272 scopus 로고
    • Negative transcriptional regulation by nuclear receptors
    • Saatcioglu, F., F.-X. Claret, and M. Karin. 1994. Negative transcriptional regulation by nuclear receptors. Semin. Cancer Biol. 5:347-359.
    • (1994) Semin. Cancer Biol. , vol.5 , pp. 347-359
    • Saatcioglu, F.1    Claret, F.-X.2    Karin, M.3
  • 6
    • 0023686772 scopus 로고
    • Negative regulation by glucocorticoids through interference with cAMP responsive enhancer
    • Akerblom, I. E., E. P. Slater, M. Beato, J. D. Baxter, and P. L. Mellon. 1988. Negative regulation by glucocorticoids through interference with cAMP responsive enhancer. Science 241:350-353.
    • (1988) Science , vol.241 , pp. 350-353
    • Akerblom, I.E.1    Slater, E.P.2    Beato, M.3    Baxter, J.D.4    Mellon, P.L.5
  • 7
    • 0026857927 scopus 로고
    • Mutual cross-interference between glucocorticoid receptor and CREB inhibits transactivation in placetal cells
    • Stauber, C., J. Altschimied, I. E. Akerblom, J. L. Marron, P. L. Mellon. 1992. Mutual cross-interference between glucocorticoid receptor and CREB inhibits transactivation in placetal cells. New Biologist 4:527-540.
    • (1992) New Biologist , vol.4 , pp. 527-540
    • Stauber, C.1    Altschimied, J.2    Akerblom, I.E.3    Marron, J.L.4    Mellon, P.L.5
  • 8
    • 0028107237 scopus 로고
    • Physical association and functional antagonism between the p65 subunit of transcription factor NFκB and the glucocorticoid receptor
    • Ray, A., and K. E. Prefontaine. 1994. Physical association and functional antagonism between the p65 subunit of transcription factor NFκB and the glucocorticoid receptor. Proc. Natl. Acacl. Sci. U.S.A. 91:752-756.
    • (1994) Proc. Natl. Acacl. Sci. U.S.A. , vol.91 , pp. 752-756
    • Ray, A.1    Prefontaine, K.E.2
  • 9
    • 0028867899 scopus 로고
    • Immunosuppression by glucocorticoids: Inhibition of NF-κB activity through induction of IκB synthesis
    • Auphan, N., J. A. DiDonato, A. Helmberg, C. Rosette, and M. Karin. 1995. Immunosuppression by glucocorticoids: Inhibition of NF-κB activity through induction of IκB synthesis. Science 270:286-290.
    • (1995) Science , vol.270 , pp. 286-290
    • Auphan, N.1    Didonato, J.A.2    Helmberg, A.3    Rosette, C.4    Karin, M.5
  • 10
    • 0028305712 scopus 로고
    • Novel mechanism of glucocorticoidmediated gene repression : NF-κB is target for glucocorticoid-mediated interleukin-8 gene repression
    • Mukaida, N., M. Morita, Y. Ishikawa, N. Rice, S. Okamoto, T. Kawahara, and K. Matsushima. 1994. Novel mechanism of glucocorticoidmediated gene repression : NF-κB is target for glucocorticoid-mediated interleukin-8 gene repression. J. Biol. Chem. 269:13289-13295.
    • (1994) J. Biol. Chem. , vol.269 , pp. 13289-13295
    • Mukaida, N.1    Morita, M.2    Ishikawa, Y.3    Rice, N.4    Okamoto, S.5    Kawahara, T.6    Matsushima, K.7
  • 12
    • 0028831128 scopus 로고
    • Characterization of mechanisms involved in transrepression of NF-κB by activated glucocorticoid receptors
    • Scheinman, R. I., A. Gualberto, C. M. Jewel, J. A. Cidlowski, and A. Baldwin, Jr. 1995. Characterization of mechanisms involved in transrepression of NF-κB by activated glucocorticoid receptors. Mol. Cell Biol. 15:943-953.
    • (1995) Mol. Cell Biol. , vol.15 , pp. 943-953
    • Scheinman, R.I.1    Gualberto, A.2    Jewel, C.M.3    Cidlowski, J.A.4    Baldwin Jr., A.5
  • 13
    • 0028879819 scopus 로고
    • Role of transcriptional activation of IκBα in mediation of immunosuppression by glucocorticoids
    • Scheinman, R. I., P. C. Cogswell, A. K. Lofquist, A. S. Baldwin, Jr. 1995. Role of transcriptional activation of IκBα in mediation of immunosuppression by glucocorticoids. Science 270:283-286.
    • (1995) Science , vol.270 , pp. 283-286
    • Scheinman, R.I.1    Cogswell, P.C.2    Lofquist, A.K.3    Baldwin Jr., A.S.4
  • 14
    • 0025720735 scopus 로고
    • The role of Jun, Fos and the AP-1 complex in cell-proliferation and transformation
    • Angel, P., and M. Karin. 1991. The role of Jun, Fos and the AP-1 complex in cell-proliferation and transformation. Biochem. Biophys. Acta 1072:129-157.
    • (1991) Biochem. Biophys. Acta , vol.1072 , pp. 129-157
    • Angel, P.1    Karin, M.2
  • 15
    • 0027232067 scopus 로고
    • NF-κB and Rel: Participants in a multiform transcriptional regulatory system
    • Grilli, M., J. J. Chiu, and M. J. Lenardo. 1993. NF-κB and Rel: participants in a multiform transcriptional regulatory system. Int. Rev. Cytol. 143:1-62.
    • (1993) Int. Rev. Cytol. , vol.143 , pp. 1-62
    • Grilli, M.1    Chiu, J.J.2    Lenardo, M.J.3
  • 16
    • 0024412752 scopus 로고
    • Transcriptional repression of eukaryotic promoters
    • Levine, M., and J. L. Manley. 1989. Transcriptional repression of eukaryotic promoters. Cell 59:405-408.
    • (1989) Cell , vol.59 , pp. 405-408
    • Levine, M.1    Manley, J.L.2
  • 17
    • 0025771222 scopus 로고
    • Interference and synergism of glucocorticoid receptor and octamer factors
    • Weiland, S., U. Dobbeling, and S. Rusconi. 1991. Interference and synergism of glucocorticoid receptor and octamer factors. EMBO J. 10:2513-2521.
    • (1991) EMBO J. , vol.10 , pp. 2513-2521
    • Weiland, S.1    Dobbeling, U.2    Rusconi, S.3
  • 18
    • 0027452405 scopus 로고
    • Retinoic acid repression of cell-specific helix-loop-helix-octamer activation of the calcitonin/calcitonin gene-related peptide enhancer
    • Lanigan, T. M., L. A. Tverberg, and A. F. Russo. 1993. Retinoic acid repression of cell-specific helix-loop-helix-octamer activation of the calcitonin/calcitonin gene-related peptide enhancer. Mol. Cell Biol. 13:6079-6088.
    • (1993) Mol. Cell Biol. , vol.13 , pp. 6079-6088
    • Lanigan, T.M.1    Tverberg, L.A.2    Russo, A.F.3
  • 19
    • 0024373683 scopus 로고
    • Eukaryotic transcriptional regulatory proteins
    • Johnson, P. F., and S. F. McKnight. 1989. Eukaryotic transcriptional regulatory proteins. Ann. Rev. Biochem. 58:799-839.
    • (1989) Ann. Rev. Biochem. , vol.58 , pp. 799-839
    • Johnson, P.F.1    McKnight, S.F.2
  • 20
    • 0023625090 scopus 로고
    • Phorbol ester-inducible genes contain a common cis clement recognized by a TPA-modulated trans-acting factor
    • Angel, P., M. Imagawa, R. Chiu, B. Stein, R. J. Imbra, H. J. Rahmsdorf, C. Jonat, P. Herrlich, and M. Karin. 1987. Phorbol ester-inducible genes contain a common cis clement recognized by a TPA-modulated trans-acting factor. Cell 49:729-739.
    • (1987) Cell , vol.49 , pp. 729-739
    • Angel, P.1    Imagawa, M.2    Chiu, R.3    Stein, B.4    Imbra, R.J.5    Rahmsdorf, H.J.6    Jonat, C.7    Herrlich, P.8    Karin, M.9
  • 21
    • 0024545638 scopus 로고
    • Gene regulation by steroid hormones
    • Beato, M. 1989. Gene regulation by steroid hormones. Cell 56:335-344.
    • (1989) Cell , vol.56 , pp. 335-344
    • Beato, M.1
  • 22
    • 0023522614 scopus 로고
    • Transcription from the stromelysin promoter is induced by interleukin-1 and repressed by dexamethasone
    • Frisch, S. M., and H. E. Ruley. 1987. Transcription from the stromelysin promoter is induced by interleukin-1 and repressed by dexamethasone. J. Biol. Chem. 262:3535-3542.
    • (1987) J. Biol. Chem. , vol.262 , pp. 3535-3542
    • Frisch, S.M.1    Ruley, H.E.2
  • 23
    • 0024211959 scopus 로고
    • Similar effect of adenovirus E1A and glucocorticoid hormones on the expression of the metalloproteinase stromelysin
    • Offringa, R., A. M. Smis, A. Houling, J. L. Bos and A. J. van der Eb. 1988. Similar effect of adenovirus E1A and glucocorticoid hormones on the expression of the metalloproteinase stromelysin. Nucl. Acids Res. 16:10974-10983.
    • (1988) Nucl. Acids Res. , vol.16 , pp. 10974-10983
    • Offringa, R.1    Smis, A.M.2    Houling, A.3    Bos, J.L.4    Van Der Eb, A.J.5
  • 24
    • 0022976481 scopus 로고
    • Half-life of synovial cell collagenase mRNA is modulated by phorbol myristate acetate but not by all trans-retinoic acid or dexamethasone
    • Brinkerhotf, C. E., I. M. Plucinska, L. A. Sheldon, and G. T. O'Connor. 1986. Half-life of synovial cell collagenase mRNA is modulated by phorbol myristate acetate but not by all trans-retinoic acid or dexamethasone. Biochemistry 25:6378-6384.
    • (1986) Biochemistry , vol.25 , pp. 6378-6384
    • Brinkerhotf, C.E.1    Plucinska, I.M.2    Sheldon, L.A.3    O'Connor, G.T.4
  • 25
    • 0025188132 scopus 로고
    • Transcriptional intererence between c-Jun and the glucocorticoid receptor: Mutual inhibition of DNA binding due to direct protein-protein interaction
    • Yang-Yen, H. F., J. C. Chambard, Y. F. Sun, T. Smeal, T. J. Schmidt, J. Druin, and M. Karin. 1990. Transcriptional intererence between c-Jun and the glucocorticoid receptor: mutual inhibition of DNA binding due to direct protein-protein interaction. Cell 62:1205-1215.
    • (1990) Cell , vol.62 , pp. 1205-1215
    • Yang-Yen, H.F.1    Chambard, J.C.2    Sun, Y.F.3    Smeal, T.4    Schmidt, T.J.5    Druin, J.6    Karin, M.7
  • 26
    • 0025130179 scopus 로고
    • Functional antagonism between oncoprotein c-Jun and the glucocorticoid receptor
    • Schule, R., P. Rangarajan, S. Kliewer, L. J. Ransone, N. Yang, I. M. Verma, and R. M. Evans. 1990. Functional antagonism between oncoprotein c-Jun and the glucocorticoid receptor. Cell 62:1217-1226.
    • (1990) Cell , vol.62 , pp. 1217-1226
    • Schule, R.1    Rangarajan, P.2    Kliewer, S.3    Ransone, L.J.4    Yang, N.5    Verma, I.M.6    Evans, R.M.7
  • 27
    • 0026316847 scopus 로고
    • Antagonism between retinoic acid and AP-1: Implications for tumor promotion and inflammation
    • Yang-Yen, H. F., X. F. Zhang, G. Graupner, M. Pfahl, and M. Karin. 1991. Antagonism between retinoic acid and AP-1: implications for tumor promotion and inflammation. New Biologist 3:1209-1219.
    • (1991) New Biologist , vol.3 , pp. 1209-1219
    • Yang-Yen, H.F.1    Zhang, X.F.2    Graupner, G.3    Pfahl, M.4    Karin, M.5
  • 28
    • 0026579203 scopus 로고
    • Interference between pathway-specific transcription factors glucocorticoids antagonize phorbol ester-induced AP-1 activity without altering AP-1 site occupation in vivo
    • Konig, H., H. Ponta, H. J. Rahmsdorf, and P. Herrlich. 1992. Interference between pathway-specific transcription factors glucocorticoids antagonize phorbol ester-induced AP-1 activity without altering AP-1 site occupation in vivo. EMBO J. 11:2241-2246.
    • (1992) EMBO J. , vol.11 , pp. 2241-2246
    • Konig, H.1    Ponta, H.2    Rahmsdorf, H.J.3    Herrlich, P.4
  • 29
    • 0025865317 scopus 로고
    • The inducible transcriptional activator NF-κB: Regulation by distinct protein subunits
    • Baeuerle, P. A. 1991. The inducible transcriptional activator NF-κB: regulation by distinct protein subunits. Biochim. Biophys. Acta 1072: 63-80.
    • (1991) Biochim. Biophys. Acta , vol.1072 , pp. 63-80
    • Baeuerle, P.A.1
  • 31
    • 0028972845 scopus 로고
    • Mechanistic aspects of NF-κB regulation: The emerging role of phosphorylation and proteolysis
    • Finco, T. S., and A. S. Baldwin. 1995. Mechanistic aspects of NF-κB regulation: the emerging role of phosphorylation and proteolysis. Immunity 3:263-273.
    • (1995) Immunity , vol.3 , pp. 263-273
    • Finco, T.S.1    Baldwin, A.S.2
  • 33
    • 0028365496 scopus 로고
    • Qualitative changes in the subunit composition of kappa B-binding complexes during murine B-cell differentiation
    • Miyamoto, S., M. J. Schmitt, and I. M. Verma. 1994. Qualitative changes in the subunit composition of kappa B-binding complexes during murine B-cell differentiation. Mol. Cell Biol. 11:5056-5060.
    • (1994) Mol. Cell Biol. , vol.11 , pp. 5056-5060
    • Miyamoto, S.1    Schmitt, M.J.2    Verma, I.M.3
  • 34
    • 0027176524 scopus 로고
    • Rapid proteolysis of IκBα is necessary for activation of transcription factor NF-κB
    • Henkel, T., T. Machleidt, I. Alkalay, M. Kronkem, Y. Ben-Neriah, and P. Baeuerle. 1993. Rapid proteolysis of IκBα is necessary for activation of transcription factor NF-κB. Nature 365:182-185.
    • (1993) Nature , vol.365 , pp. 182-185
    • Henkel, T.1    Machleidt, T.2    Alkalay, I.3    Kronkem, M.4    Ben-Neriah, Y.5    Baeuerle, P.6
  • 35
    • 0028967819 scopus 로고
    • Inducible nuclear expression of newly synthesized Iκbα negatively regulates DNA-binding and transcriptional activities of NF-κB
    • Arenza-Seisdedos, F., J. Thomspon, M. S. Rodriguez, F. Bachelerie, D. Thomas, and R. Hay. 1995. Inducible nuclear expression of newly synthesized Iκbα negatively regulates DNA-binding and transcriptional activities of NF-κB. Mol. Cell Biol. 15:2689-2696.
    • (1995) Mol. Cell Biol. , vol.15 , pp. 2689-2696
    • Arenza-Seisdedos, F.1    Thomspon, J.2    Rodriguez, M.S.3    Bachelerie, F.4    Thomas, D.5    Hay, R.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.