Recruitment of the SWI-SNF chromatin remodeling complex as a mechanism of gene activation by the glucocorticoid receptor τ1 activation domain

Molecular and Cellular Biology

Volumn 20, Issue 6, 2000, Pages 2004-2013

  Wallberg, Annika E ^a,d   Neely, Kristen E ^c   Hassan, Ahmed H ^c   Gustafsson, Jan åke ^a   Workman, Jerry L ^c   Wright, Anthony P H ^b  

^a KAROLINSKA INSTITUTE   (Sweden)

^b SÖDERTÖRN UNIVERSITY   (Sweden)

^c PENNSYLVANIA STATE UNIVERSITY   (United States)

^d ROCKEFELLER UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOCORTICOID RECEPTOR; TRANSCRIPTION FACTOR;

ARTICLE; CHROMATIN STRUCTURE; CONTROLLED STUDY; GENE ACTIVATION; HELA CELL; HUMAN; HUMAN CELL; NUCLEOSOME; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DNA BINDING; TRANSACTIVATION;

AMINO ACID SEQUENCE; CELL LINE; CHROMATIN; FUNGAL PROTEINS; GENE EXPRESSION REGULATION; HUMANS; MOLECULAR SEQUENCE DATA; RECEPTORS, GLUCOCORTICOID; SACCHAROMYCES CEREVISIAE; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS; TRANSFECTION;

MAMMALIA;

EID: 0033999965     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.20.6.2004-2013.2000     Document Type: Article

References (50)

1. Almlöf, T., A. P. H. Wright, and J.-Å. Gustafsson. 1995. Role of acidic and phosphorylated residues in gene activation by the glucocorticoid receptor. J. Biol. Chem. 270:17535-17540.
2. Almlöf, T., J.-Å. Gustafsson, and A. P. H. Wright. 1997. Role of hydrophobic amino acid clusters in the transactivation activity of the human glucocorticoid receptor. Mol. Cell. Biol. 17:934-945.
3. Almlöf, T., A. E. Wallberg, J.-Å. Gustafsson, and A. P. H. Wright. 1998. Role of important hydrophobic amino acids in the interaction between the glucocorticoid receptor τ1-core activation domain and target factors. Biochemistry 37:9585-9594.
4. Biggar, S. R., and G. R. Crabtree. 1999. Continuous and widespread roles for the Swi-Snf complex in transcription. EMBO J. 18:2254-2264.
5. Bohen, S. P., and K. R. Yamamoto. 1993. Isolation of Hsp90 mutants by screening for decreased steroid receptor function. Proc. Natl. Acad. Sci. USA 90:11424-11428.
6. Burns, L. G., and C. L. Peterson. 1997. The yeast SWI-SNF complex facilitates binding of a transcriptional activator to nucleosomal sites in vivo. Mol. Cell. Biol. 17:4811-4819.
7. Cairns, B. R., Y. J. Kim, M. H. Sayre, B. C. Laurent, and R. D. Kornberg. 1994. A multisubunit complex containing the Swi1/Adr6, Swi2/Snf2, Swi3, Snf5, and Snf6 gene products isolated from yeast. Proc. Natl. Acad. Sci. USA 91:1950-1954.
8. Chiang, Y. C., P. Komarnitsky, D. Chase, and C. L. Denis. 1996. ADR1 activation domains contact the histone acetyltransferase GCN5 and the core transcriptional factor TFIIB. J. Biol. Chem. 271:32359-32365.
9. Cosma, M.-P., T. Tanaka, and K. Nasmyth. 1999. Ordered recruitment of transcription and chromatin remodelling factors to a cell cycle and developmentally regulated promoter. Cell 97:299-311.
10. Côte, J., J. Quinn, J. L. Workman, and C. L. Peterson. 1994. Stimulation of Ga14 derivative binding to nucleosomal DNA by the yeast Swi/Snf complex. Science 265:53-60.
11. Côte, J., R. T. Utley, and J. L. Workman. 1995. Basic analysis of transcription factor binding to nucleosomes. Methods Mol. Genet. 6:108-129.
12. Dahlman-Wright, K., T. Almlöf, I. J. McEwan, J.-Å. Gustafsson, and A. P. H. Wright. 1994. Delination of a small region within the major transactivation domain of the human glucocorticoid receptor that mediates transactivation of gene expression. Proc. Natl. Acad. Sci. USA 91:1619-1623.
13. Dahlman-Wright, K., H. Baumann, I. J. McEwan, T. Almlöf, A. P. H. Wright, J.-Å. Gustafsson, and T. Härd. 1995. Structural characterization of a minimal functional transactivation domain from the human glucocorticoid receptor. Proc. Natl. Acad. Sci. USA 92:1699-1703.
14. Di Crose, L., R. Koop, P. Venditti, H. M. Westphal, K. P. Nightingale, D. F. V. Corona, P. B. Becker, and M. Beato. 1999. Two-step synergism between the progesterone receptor and the DNA-binding domain of nuclear factor 1 on MMTV minichromosomes. Mol. Cell 4:45-54.
15. Ford, J., I. J. McEwan, A. P. H. Wright, and J.-Å. Gustafsson. 1997. Involvement of the TFIID protein complex in gene activation by the N-terminal transactivation domain of the glucocorticoid receptor in vitro. Mol. Endocrinol. 11:1467-1475.
16. Fryer, C. J., and T. K. Archer. 1998. Chromatin remodelling by the glucocorticoid receptor requires the BRG1 complex. Nature 393:88-91.
17. Gavin, I. M., and R. T. Simpson. 1997. Interplay of yeast global transcriptional regulators Ssn6p-Tup1p and Swi-Snf and their effect on chromatin structure. EMBO J. 16:6263-6271.
18. Gietz, R. D., and R. H. Schiestl. 1991. Applications of high efficiency lithium acetate transformation of intact yeast cells using single stranded nucleic acids as carrier. Yeast 7:253-263.
19. Grant, P. A., L. Duggan, J. Côte, S. M. Roberts, J. E. Brownell, R. Candau, R. Ohba, T. Owenhughes, C. D. Allis, F. Winston, S. L. Berger, and J. L. Workman. 1997. Yeast Gcn5 functions in two multisubunit complexes to acetylate nucleosomal histones: characterization of an Ada complex and the SAGA (Spt/Ada) complex. Genes Dev. 11:1640-1650.
20. Hagemeier, C., A. Cook, and T. Kouzarides. 1993. The retinoblastoma protein binds E2F residues required for activation in vivo and TBP binding in vitro. Nucleic Acids Res. 21:4998-5004.
21. Henriksson, A., T. Almlöf, J. Ford, I. J. McEwan, J.-Å. Gustafsson, and A. P. H. Wright. 1997. Role of the Ada adaptor complex in gene activation by the glucocorticoid receptor. Mol. Cell. Biol. 17:3065-3073.
22. Horvath, A., and H. Riezman. 1994. Rapid protein extraction from Saccharomyces cerevisiae. Yeast 10:1305-1310.
23. Ichinose, H., J.-M. Garnier, P. Chambon, and R. Losson. 1997. Ligand-dependent interaction between the estrogen receptor and the human homologues of SWI2/SNF2. Gene 188:95-100.
24. Ikeda, K., D. Steger, A. Eberharter, and J. L. Workman. 1999. Activation domain-specific and general transcription stimulation by native histone acetyltransferase complexes. Mol. Cell. Biol. 19:855-863.
25. Imbalzano, A. N., H. Kwon, M. R. Green, and R. E. Kingston. 1994. Facilitated binding of TATA-binding protein to nucleosomal DNA. Nature 370: 481-485.
26. Iniguez-Lluhi, J. A., D. Y. Lou, and K. R. Yamamoto. 1997. Three amino acid substitutions selectively disrupt the activation but not the repression function of the glucocorticoid receptor N terminus. J. Biol. Chem. 272:4149-4156.
27. Krebs, J. E., M.-H. Kuo, C. D. Allis, and C. L. Peterson. 1999. Cell cycle-regulated histone acetylation required for expression of the yeast HO gene. Genes Dev. 13:1412-1421.
28. Lind, U., J. Carlstedt-Duke, J.-Å. Gustafsson, and A. P. H. Wright. 1996. Identification of single amino acid substitutions of Cys-736 that affect the steroid-binding affinity and specificity of the glucocorticoid receptor using phenotypic screening in yeast. Mol. Endocrinol. 10:1358-1370.
29. McEwan, I. J., A. P. Wright, K. Dahlman-Wright, J. Carlstedt-Duke, and J.-Å. Gustafsson. 1993. Direct interaction of the tau 1 transactivation domain of the human glucocorticoid receptor with the basal transcription machinery. Mol. Cell. Biol. 13:399-407.
30. McEwan, I. J., T. Almlöf, A.-C. Wikström, K. Dahlman-Wright, A. P. Wright, and J.-Å. Gustafsson. 1994. The glucocorticoid receptor functions at multiple steps during transcription initiation by RNA polymerase II. J. Biol. Chem. 269:25629-25636.
31. Melcher, K., and S. A. Johnston. 1995. GAL4 interacts with TATA-binding protein and coactivators. Mol. Cell. Biol. 15:2839-2848.
32. Muchardt, C., and M. Yaniv. 1993. A human homologue of Saccharomyces cerevisiae SNF2/SWI2 and Drosophila brm genes potentiates transcriptional activation by the glucocorticoid receptor. EMBO J. 12:4279-4290.
33. Natarajan, K., B. M. Jackson, H. Zhou, F. Winston, and A. G. Hinnebusch. 1999. Transcriptional activation by Gcn4p involves independent interactions with the SWI/SNF complex and the SRB/Mediator. Mol. Cell 4:657-664.
34. Neely, K. E., A. H. Hassan, A. E. Wallberg, D. J. Steger, B. R. Cairns, A. P. H. Wright, and J. L. Workman. 1999. Activation domain-mediated targeting of the SWI/SNF complex to promoters stimulates transcription from nucleosome arrays. Mol. Cell 4:649-655.
35. Östlund-Farrants, A.-K., P. Blomquist, H. Kwon, and Ö. Wrange. 1997. Glucocorticoid receptor-glucocorticoid response element binding stimulates nucleosome disruption by the SWI/SNF complex. Mol. Cell. Biol. 17:895-905.
36. Paranjape, S. M., R. T. Kamakaka, and J. T. Kadonaga. 1994. Role of chromatin structure in the regulation of transcription by RNA polymerase II. Annu. Rev. Biochem. 63:265-297.
37. Pollard, K. J., and C. L. Peterson. 1997. Role for ADA/GCN5 products in antagonizing chromatin-mediated transcriptional repression. Mol. Cell. Biol. 17:6212-6222.
38. Roberts, S. M., and F. Winston. 1997. Essential functional interactions of SAGA, a Saccharomyces cerevisiae complex of Spt, Ada, and Gcn5 proteins, with the Snf/Swi and Srb/Mediator complexes. Genetics 147:451-465.
39. Silverman, N., J. Agapite, and L. Guarente. 1994. Yeast Ada2 protein binds to the VP16 protein activation domain and activates transcription. Proc. Natl. Acad. Sci. USA 91:11665-11668.
40. Steger, D. J., A. Eberharter, S. John, P. A. Grant, and J. L. Workman. 1998. Purified histone acetyltransferase complexes stimulate HIV-1 transcription from preassembled nucleosomal arrays. Proc. Natl. Acad. Sci. USA 95: 12924-12929.
41. Steger, D. J., and J. L. Workman. Transcriptional analysis of purified histone acetyltransferase complexes. Methods, in press.
42. Utley, R. T., K. Ikeda, P. A. Grant, J. Côte, D. J. Steger, A. Eberharter, S. John, and J. L. Workman. 1998. Transcriptional activators target histone acetyltransferase complexes to nucieosomes. Nature 394:498-502.
43. Wallberg, A. E., K. E. Neely, J.-Å. Gustafsson, J. L. Workman, A. P. H. Wright, and P. A. Grant. 1999. Histone acetyltransferase complexes can mediate transcriptional activation by the major glucocorticoid receptor activation domain. Mol. Cell. Biol. 19:5952-5959.
44. Wilson, C. J., D. M. Chao, A. N. Imbalzano, G. R. Schnitzler, R. E. Kingston, and R. A. Young. 1996. RNA polymerase II holoenzyme contains SWI/SNF regulators involved in chromatin remodelling. Cell 84:235-244.
45. Wright, A. P. H., J. Carlstedt-Duke, and J.-Å. Gustafsson. 1990. Ligand-specific transactivation of gene expression by a derivative of the human glucocorticoid receptor expressed in yeast. J. Biol. Chem. 265:14763-14769.
46. Wright, A. P. H., I. J. McEwan, K. Dahlman-Wright, and J.-Å. Gustafsson. 1991. High level expression of the major transactivation domain of the human glucocorticoid receptor in yeast cells inhibits endogenous gene expression and cell growth. Mol. Endocrinol. 5:1366-1372.
47. Wright, A. P. H., and J.-Å. Gustafsson. 1991. Mechanism of synergistic transcriptional transactivation by the human glucocorticoid receptor. Proc. Natl. Acad. Sci. USA 88:8283-8287.
48. Wu, L., and F. Winston. 1997. Evidence that Snf-Swi controls chromatin structure over both the TATA and UAS regions of the SUC2 promoter in Saccharomyces cerevisiae. Nucleic Acids Res. 25:4230-4234.
49. Yoshinaga, S. K., C. L. Peterson, I. Herskowitz, and K. R. Yamamoto. 1992. Roles of SWIl, SWI2, and SWI3 proteins for transcriptional enhancement by steroid receptors. Science 258:1598-1604.
50. Yudkovsky, N., C. Logie, S. Hahn, and C. L. Peterson. 1999. Recruitment of the SWI/SNF chromatin complex by transcriptional activators. Genes Dev. 13:2369-2374.