High constitutive glucocorticoid receptor β in human neutrophils enables them to reduce their spontaneous rate of cell death in response to corticosteroids

Journal of Experimental Medicine

Volumn 193, Issue 5, 2001, Pages 585-593

  Strickland, Ian ^a   Kisich, Kevin ^a   Hauk, Pia J ^a   Vottero, Alessandra ^c   Chrousos, George P ^c   Klemm, Dwight J ^a   Leung, Donald Y M ^a,b  

^a NATIONAL JEWISH MEDICAL AND RESEARCH CENTER   (United States)

^b UNIVERSITY OF COLORADO   (United States)

^c EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

Author keywords

Glucocorticoid insensitivity; Glucocorticoid receptor; Inflammation; Interleukin 8; Neutrophils

Indexed keywords

DEXAMETHASONE; GLUCOCORTICOID RECEPTOR; GLUCOCORTICOID RECEPTOR BETA; INTERLEUKIN 8; MESSENGER RNA; RECEPTOR SUBTYPE; UNCLASSIFIED DRUG;

ARTICLE; CELL DEATH; CELL LEVEL; CELL STIMULATION; CELL SURVIVAL; CONTROLLED STUDY; DRUG SENSITIVITY; GENE EXPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE TEST; IMMUNOPRECIPITATION; INFLAMMATION; MONONUCLEAR CELL; NEUTROPHIL; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR UPREGULATION; WESTERN BLOTTING;

ADRENAL CORTEX HORMONES; ANIMALS; BLOTTING, WESTERN; CELL DEATH; CELL SEPARATION; CELLS, CULTURED; DEXAMETHASONE; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; GENE EXPRESSION; HUMANS; INTERLEUKIN-8; LEUKOCYTES, MONONUCLEAR; MICE; MICE, INBRED BALB C; NEUTROPHILS; RECEPTORS, GLUCOCORTICOID; RNA, MESSENGER; SPECIES SPECIFICITY; TRANSFECTION;

EID: 0035809314     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.193.5.585     Document Type: Article

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