Glucocorticoid receptor gene and risk of cardiovascular disease

Archives of Internal Medicine

Volumn 168, Issue 1, 2008, Pages 33-39

  Van Den Akker, Erica L T ^a   Koper, Jan W ^a   Van Rossum, Elisabeth F C ^a   Dekker, Marieke J H ^a   Russcher, Henk ^a   De Jong, Frank H ^a   Uitterlinden, Andre G ^a   Hofman, Albert ^a   Pols, Huibert A ^a   Witteman, Jacqueline C M ^a   Lamberts, Steven W J ^a  

^a ERASMUS MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

C REACTIVE PROTEIN; GLUCOCORTICOID RECEPTOR; INTERLEUKIN 6;

ADULT; AGED; ARTERY INTIMA PROLIFERATION; ARTERY MEDIA; ARTICLE; CARDIOVASCULAR DISEASE; CARDIOVASCULAR RISK; CAROTID ARTERY; CONFIDENCE INTERVAL; CORONARY RISK; FEMALE; GENETIC RISK; HEART INFARCTION; HETEROZYGOTE; HOMOZYGOSITY; HUMAN; ISCHEMIC HEART DISEASE; MAJOR CLINICAL STUDY; MALE; POPULATION RESEARCH; PRIORITY JOURNAL; PROSPECTIVE STUDY; PROTEIN BLOOD LEVEL; RECEPTOR GENE; RISK ASSESSMENT;

AGED; C-REACTIVE PROTEIN; CARDIOVASCULAR DISEASES; CORONARY DISEASE; FEMALE; FOLLOW-UP STUDIES; GENETIC PREDISPOSITION TO DISEASE; HAPLOTYPES; HUMANS; HYDROCORTISONE; INTERLEUKIN-6; MALE; MIDDLE AGED; MYOCARDIAL INFARCTION; PROSPECTIVE STUDIES; RECEPTORS, GLUCOCORTICOID;

EID: 38349076030     PISSN: 00039926     EISSN: 15383679     Source Type: Journal    
DOI: 10.1001/archinternmed.2007.41     Document Type: Article

References (23)

1. Schuit SC, Oei HH, Witteman JC, et al. Estrogen receptor alpha gene polymorphisms and risk of myocardial infarction. JAMA. 2004;291(24):2969-2977.
2. Zee RY, Cook NR, Cheng S, Erlich HA, Lindpaintner K, Ridker PM. Multi-locus candidate gene polymorphisms and risk of myocardial infarction: a population-based, prospective genetic analysis. J Thromb Haemost. 2006;4(2):341-348.
3. Libby P. Inflammation in atherosclerosis. Nature. 2002;420(6917):868-874.
4. Ridker PM, Wilson PW, Grundy SM. Should C-reactive protein be added to metabolic syndrome and to assessment of global cardiovascular risk? Circulation. 2004;109(23):2818-2825.
5. Rhen T, Cidlowski JA. Antiinflammatory action of glucocorticoids-new mechanisms for old drugs. N Engl J Med. 2005;353(16):1711-1723.
6. Huizenga NA, Koper JW, de Lange P, et al. Interperson variability but intraperson stability of baseline plasma cortisol concentrations, and its relation to feedback sensitivity of the hypothalamo-pituitary-adrenal axis to a low dose of dexamethasone in elderly individuals. J Clin Endocrinol Metab. 1998;83(1):47-54.
7. van Rossum EF, Lamberts SW. Polymorphisms in the glucocorticoid receptor gene and their associations with metabolic parameters and body composition. Recent Prog Horm Res. 2004;59:333-357.
8. Kuningas M, Mooijaart SP, Slagboom PE, Westendorp RGJ, Heemst D. Genetic variants in the glucocorticoid receptor gene (NR3C1) and cardiovascular disease risk: the Leiden 85-plus study. Biogerontology. 2006;7(4):231-238.
9. Lin RC, Wang XL, Morris BJ. Association of coronary artery disease with glucocorticoid receptor N363S variant. Hypertension. 2003;41(3):404-407.
10. van den Akker EL, Nouwen JL, Melles DC, et al. Staphylococcus aureus nasal carriage is associated with glucocorticoid receptor gene polymorphisms. J Infect Dis. 2006;194(6):814-818.
11. van den Akker EL, Russcher H, van Rossum EF, et al. Glucocorticoid receptor polymorphism affects transrepression but not transactivation. J Clin Endocrinol Metab. 2006;91(7):2800-2803.
12. Hofman A, Grobbee DE, de Jong PT, van den Ouweland FA. Determinants of disease and disability in the elderly: the Rotterdam Elderly Study. Eur J Epidemiol. 1991;7(4):403-422.
13. Guidelines Subcommittee. 1999 World Health Organization-International Society of Hypertension Guidelines for the Management of Hypertension. J Hypertens. 1999;17(2):151-183.
14. World Health Organization. Diabetes Mellitus. Geneva, Switzerland: World Health Organization; 1985. Technical Report Series 727.
15. van der Meer IM, Bots ML, Hofman A, del Sol AI, van der Kuip DA, Witteman JC. Predictive value of noninvasive measures of atherosclerosis for incident myocardial infarction: the Rotterdam Study. Circulation. 2004;109(9):1089-1094.
16. Mattace-Raso FU, van der Cammen TJ, van der Meer IM, et al. C-reactive protein and arterial stiffness in older adults: the Rotterdam Study. Atherosclerosis. 2004;176(1):111-116.
17. Stephens M, Smith NJ, Donnelly P. A new statistical method for haplotype reconstruction from population data. Am J Hum Genet. 2001;68(4):978-989.
18. World Health Organization. International Statistical Classification of Diseases, 10th Revision (ICD-10). Geneva, Switzerland: World Health Organization; 1992.
19. Ridker PM, Brown NJ, Vaughan DE, Harrison DG, Mehta JL. Established and emerging plasma biomarkers in the prediction of first atherothrombotic events. Circulation. 2004;109(25)(suppl 1):IV6-IV19.
20. Schaaf MJ, Cidlowski JA. AUUUA motifs in the 3′UTR of human glucocorticoid receptor alpha and beta mRNA destabilize mRNA and decrease receptor protein expression. Steroids. 2002;67(7):627-636.
21. Derijk RH, Schaaf MJ, Turner G, et al. A human glucocorticoid receptor gene variant that increases the stability of the glucocorticoid receptor beta-isoform mRNA is associated with rheumatoid arthritis. J Rheumatol. 2001;28(11):2383-2388.
22. Ogawa S, Lozach J, Benner C, et al. Molecular determinants of crosstalk between nuclear receptors and toll-like receptors. Cell. 2005;122(5):707-721.
23. Kolek MJ, Carlquist JF, Muhlestein JB, et al. Toll-like receptor 4 gene Asp299Gly polymorphism is associated with reductions in vascular inflammation, angiographic coronary artery disease, and clinical diabetes. Am Heart J. 2004;148(6):1034-1040.