Surface cathepsin B protects cytotoxic lymphocytes from self-destruction after degranulation

Journal of Experimental Medicine

Volumn 196, Issue 4, 2002, Pages 493-503

  Balaji, Kithiganahalli N ^a   Schaschke, Norbert ^b   Machleidt, Werner ^c   Catalfamo, Marta ^a   Henkart, Pierre A ^a,d  

^a NATIONAL CANCER INSTITUTE   (United States)

^b MAX PLANCK INSTITUTE OF BIOCHEMISTRY   (Germany)

^c UNIVERSITY OF MUNICH   (Germany)

^d NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

CTL; Cytotoxicity; Exocytosis; Granule; Protease

Indexed keywords

CALCIUM; CATHEPSIN B; PERFORIN; PROTEINASE; PROTEINASE INHIBITOR;

ANIMAL CELL; ARTICLE; BIOTINYLATION; CELL PROTECTION; CELL SURFACE; CHELATION; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; CYTOTOXICITY; DEGRANULATION; EXOCYTOSIS; FLOW CYTOMETRY; HUMAN; HUMAN CELL; KNOCKOUT MOUSE; MODEL; MOUSE; NATURAL KILLER CELL; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; ANTIGENS, CD3; CATHEPSIN B; CELL DEGRANULATION; CELL MEMBRANE; CYSTATINS; CYSTEINE PROTEINASE INHIBITORS; CYTOTOXICITY TESTS, IMMUNOLOGIC; DIAZOMETHANE; DIPEPTIDES; EXOCYTOSIS; HUMANS; KETONES; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, KNOCKOUT; OLIGOPEPTIDES; T-LYMPHOCYTES, CYTOTOXIC;

EID: 0037136311     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.20011836     Document Type: Article

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