Estrogen and progesterone receptors: From molecular structures to clinical targets

Cellular and Molecular Life Sciences

Volumn 66, Issue 15, 2009, Pages 2405-2426

  Ellmann, Stephan ^a   Sticht, Heinrich ^b   Thiel, Falk ^a   Beckmann, Matthias W ^a   Strick, Reiner ^a   Strissel, Pamela L ^a  

^a UNIVERSITY HOSPITAL ERLANGEN   (Germany)

^b UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

Author keywords

Breast and endometrial carcinoma; Crystal structures; Estrogen and progesterone receptors; SERMs and tamoxifen

Indexed keywords

6 HYDROXY 2 (4 HYDROXYPHENYL) 3 [4 [2 (1 PYRROLIDINYL)ETHOXY]BENZOYL]BENZO[B]THIOPHENE; ACOLBIFENE; ANTIESTROGEN; ARZOXIFENE; ASOPRISNIL; BAZEDOXIFENE; CLOMIFENE; CLOMIFENE CITRATE; CYCLIC AMP DEPENDENT PROTEIN KINASE; DROLOXIFENE; DROSPIRENONE; DROSPIRENONE PLUS ETHINYLESTRADIOL; ESTRADIOL; ESTROGEN RECEPTOR; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; ETHINYLESTRADIOL PLUS LEVONORGESTREL; FABLYN; FULVESTRANT; IC 182 780; ICI 164 384; LASOFOXIFENE; MIFEPRISTONE; NORGESTIMATE; NORGESTREL; ONAPRISTONE; ORTHO CYCLEN 21; OSPEMIFENE; PIPENDOXIFENE; PROGESTERONE; PROGESTERONE RECEPTOR; PROGESTERONE RECEPTOR MODULATOR; RALOXIFENE; SELECTIVE ESTROGEN RECEPTOR MODULATOR; TAMOXIFEN; TAMOXIFEN CITRATE; TOREMIFENE; UNCLASSIFIED DRUG; UNINDEXED DRUG;

BREAST CANCER; BREAST CARCINOMA; CLINICAL TRIAL; DRUG EFFECT; DRUG RECEPTOR BINDING; DRUG TARGETING; ENDOMETRIOSIS; ENDOMETRIUM CANCER; GENE CONTROL; HORMONE ACTION; HUMAN; HYPERCORTISOLISM; INFERTILITY; LEIOMYOMA; LOW DRUG DOSE; NONHUMAN; OSTEOPOROSIS; PROSTATE CANCER; PROTEIN DOMAIN; PROTEIN STRUCTURE; RECEPTOR INTRINSIC ACTIVITY; REVIEW; SIGNAL TRANSDUCTION; STRUCTURE ANALYSIS; UTERUS MYOMA; VAGINA ATROPHY;

AMINO ACID SEQUENCE; ANIMALS; COMPUTATIONAL BIOLOGY; ESTRADIOL; HUMANS; LIGANDS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PHYLOGENY; PROGESTERONE; PROTEIN ISOFORMS; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, ESTROGEN; RECEPTORS, PROGESTERONE; RECEPTORS, STEROID; SELECTIVE ESTROGEN RECEPTOR MODULATORS; SEQUENCE ALIGNMENT; SIGNAL TRANSDUCTION;

EID: 67650803266     PISSN: 1420682X     EISSN: 15691632     Source Type: Journal    
DOI: 10.1007/s00018-009-0017-3     Document Type: Review

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