Ligand-dependent transcription activation by nuclear receptors requires the DRIP complex

Nature

Volumn 398, Issue 6730, 1999, Pages 824-828

  Rachez, Christophe ^a   Lemon, Bryan D ^b   Suldan, Zalman ^a   Bromleigh, Virginia ^a   Gamble, Matthew ^a   Näär, Anders M ^b   Erdjument Bromage, Hediye ^a   Tempst, Paul ^a   Freedman, Leonard P ^a  

^a Weill Cornell Graduate School of Biomedical Sciences   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL NUCLEUS RECEPTOR; COMPLEMENTARY DNA; LIGAND; VITAMIN D RECEPTOR;

AMINO ACID SEQUENCE; ARTICLE; COMPLEX FORMATION; GENETIC TRANSCRIPTION; HUMAN; LIGAND BINDING; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RECEPTOR BINDING; REGULATORY MECHANISM; SEQUENCE ANALYSIS; TRANSACTIVATION; TRANSCRIPTION REGULATION;

AMINO ACID SEQUENCE; ANIMALS; CARRIER PROTEINS; CHROMATIN; CLONING, MOLECULAR; DROSOPHILA; HELA CELLS; HUMANS; LIGANDS; MACROMOLECULAR SUBSTANCES; MICE; MOLECULAR SEQUENCE DATA; NUCLEAR PROTEINS; RECEPTORS, CALCITRIOL; SEQUENCE HOMOLOGY, AMINO ACID; TRANS-ACTIVATION (GENETICS); TRANS-ACTIVATORS; TRANSCRIPTION FACTORS;

EID: 0033614417     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/19783     Document Type: Article

References (29)

1. Torchia, J., Glass, C. & Rosenfeld, M. G. Co-activators and co-repressors in the integration of transcriptional responses. Curr. Opin. Cell Biol. 10, 373-383 (1998).
2. Rachez, C. et al. A novel protein complex that interacts with the vitamin D3 receptor in a ligand-dependent manner and enhances VDR transactivation in a cell-free system. Genes Dev. 12, 1787-1800 (1998).
3. Fondell, J. D., Ge, H. & Roeder, R. G. Ligand induction of a transcriptionally active thyroid hormone receptor coactivator comples. Proc. Natl Acad. Sci. USA 93, 8329-8333 (1996).
4. Nään A. M. et al. Chromatin, TAFs, and a novel multiprotein coactivator are required for synergistic activation by Sp1 and SREBP-1a in vitro. Genes Dev. 12, 3020-3031 (1998)
5. Näär, A. M. et al. Composite co-activator ARC mediates chromatin-directed transcriptional activation. Nature 398, 828-832 (1999).
6. Ryu, S., Zhou, S., Ladurner, A. G. & Tjian, R. The transcriptional co-factor complex CRSP is required for Sp1 activity. Nature 397, 446-450 (1999).
7. Sun, X. et al. NAT, a human complet containing Srb polypeptides that functions as a negative regulator of activated transcription. Mol. Cell 2, 213-222 (1998).
8. Gu, W. et al. A novel human SRB/MED-containing cofactor complex, SMCC, involved in transcription regulation. Mol. Cell 3, 97-108 (1999).
9. Jiang, Y. W. et al. Mammalian mediator of transcriptional regulation and its possible role as end-point of signal transduction pathways. Proc. Natl Acad. Sci. USA 95, 8538-8543 (1998).
10. Moras, D. & Gronemeyer, H. The nuclear receptor ligand-binding domain: structure and function. Curr. Opin. Cell Biol. 10, 384-391 (1998).
11. Drane, P., Barel, M., Balbo, M. & Frade, R. Identification of RB18A, a 205 kDa new p53 regulatory protein which shares antigenic and functional properties with p53. Oncogene 15, 3013-3024 (1997).
12. Yuan, C. X., Ito, M., Fondell, J. D., Fu, Z. Y. & Roeder, R. G. The TRAP220 component of a thyroid hormone receptor-associated protein (TRAP) coactivator complex interacts directly with nuclear receptors in a ligand-dependent fashion. Proc. Natl Acad. Sci. USA 95, 7939-7944 (1998).
13. 1 a protein that interacts with peroxisome proliferator-activated receptor. J. Biol. Chem. 272, 25500-25506 (1997).
14. Lee, J. W., Choi, H. S., Gyuris, J., Brent, R. & Moore, D. D. Two classes of proteins dependent on either the presence or absence of thyroid hormone for interaction with the thyroid hormone receptor. Mol. Endocrinol. 9, 243-254 (1995).
15. Nagase, T., Seki, N., Tanaka, A., Ishikawa, K. & Nomura, N. Prediction of the coding sequences of unidentified human genes. IV. The coding sequences of 40 new genes (KIAA0121-KIAA0160) deduced by analysis of cDNA clones from human cell line KG-1. DNA Res. 2, 167-174 (1995).
16. Li, Y. et al. Yeast global transcriptional regulators Sin4 and Rgr1 are components of mediator complex/ RNA polymerase II holoenzyme. Proc. Natl Acad. Sci. USA 92, 10864-10868 (1995).
17. Yoshikawa, H., Fujiyama, A., Nakai, K., Inazawa, J. & Matsubara, K. Detection and isolation of a novel human gene located on Xp11.2-p11.4 that escapes X-inactivation using a two-dimensional DNA mapping method. Genomics 49, 237-246 (1998).
18. McInerney, E. M. et al. Determinants of coactivator LXXLL motif specificity in nuclear receptor transcriptional activation. Genes Dev. 12, 3357-3368 (1998).
19. Darimont, B. D. et al. Structure and specificity of nuclear receptor-coactivator interactions. Genes Dev. 12, 3343-3356 (1998).
20. Heery, D. M., Kalkhoven, E., Hoare, S. & Parker, M. G. A signature motif in transcriptional coactivators mediates binding to nuclear receptors. Nature 387, 733-736 (1997).
21. Torchia, J. et al. The transcriptional co-activator p/CIP binds CBP and mediates nuclear-receptor function. Nature 387, 677-686 (1997).
22. Le Douarin, B. et al. A possible involvement of IF1 alpha and TIF1 beta in the epigenetic control of transcription by nuclear receptors. EMBO J. 15, 6701-6715 (1996).
23. Lemon, B. D., Fondell, J. D. & Freedman, L. P. Retinoid X receptor:vitamin D3 receptor heterodimers promote stable preinitiation complex formation and direct 1,25-dihydroxyvitamin D3-dependent cell-free transcription. Mol. Cell. Biol. 17, 1923-1937 (1997).
24. Kraus, W. L. & Kadonaga, J. T. p300 and estrogen receptor cooperatively activate transcription via differential enhancement of initiation and reinitiation. Genes Dev. 12, 331-342 (1998).
25. Lui, M., Tempst, P. & Erdjument-Bromage, H. Methodical analysis of protein-nitrocellulose interactions to design a refined digestion protocol. Analyt. Biochem. 241, 156-166 (1996).
26. Erdjument-Bromage, H. et al. Examination of micro-tip reversed-phase liquid chromatographic extraction of peptide pools for mass spectrometric analysis. J. Chromatogr. 826, 167-181 (1998).
27. Geromanos, S., Philip, J., Freckleton, G. & Tempst, P. Injection adaptable fine ionization source ('JaFIS') for continuous flow nano-electrospray. Rapid Commun. Mass Spectrom. 12, 551-556 (1998).
28. Mann, M. & Wilm, M. Error-tolerant identification of peptides in sequence databases by peptide sequence tags. Analyt. Chem. 66, 4390-4399 (1994).
29. Kamakaka, R. T., Bulger, M. & Kadonaga, J. T. Potentiation of RNA polymerase II transcription by Gal4-VP16 during but not after DNA replication and chromatin assembly. Genes Dev. 7, 1779-1795 (1993).