-
1
-
-
33846457870
-
Cancer Statistics, 2007
-
Jemal A, Siegel R, Ward F, et al. Cancer Statistics, 2007. CA Cancer J Clin 2007;57:43-66
-
(2007)
CA Cancer J Clin
, vol.57
, pp. 43-66
-
-
Jemal, A.1
Siegel, R.2
Ward, F.3
-
2
-
-
44949096149
-
-
Ferlay J, Bray F, Pisani P, et al. Globocan 2000: cancer incidence, mortality and prevalence worldwide, Version 1.0 Lyon: IARC Cancer Base No. 5. IARC Press; 2001
-
Ferlay J, Bray F, Pisani P, et al. Globocan 2000: cancer incidence, mortality and prevalence worldwide, Version 1.0 Lyon: IARC Cancer Base No. 5. IARC Press; 2001
-
-
-
-
3
-
-
34247241630
-
The decrease in breast cancer incidence in 2003 in the United States
-
Ravdin PM, Cronin KA, Howlandr N, et al. The decrease in breast cancer incidence in 2003 in the United States. N Engl J Med 2007;356:1670-4
-
(2007)
N Engl J Med
, vol.356
, pp. 1670-1674
-
-
Ravdin, P.M.1
Cronin, K.A.2
Howlandr, N.3
-
4
-
-
33847172907
-
Recent declines in hormone therapy utilization and breast cancer incidence: Clinical and population-based evidence
-
Clarke CA, Glaser SL, Uratsu CS, et al. Recent declines in hormone therapy utilization and breast cancer incidence: clinical and population-based evidence. J Clin Oncol 2006;24:e49-50
-
(2006)
J Clin Oncol
, vol.24
-
-
Clarke, C.A.1
Glaser, S.L.2
Uratsu, C.S.3
-
5
-
-
0037125379
-
Risk and benefits of estrogen plus progestin in healthy postmenopausal women: Principal results from the Women's Health Initiative randomized controlled trial
-
Rossouw JE, Anderson JL, Prentice RL, et al. Risk and benefits of estrogen plus progestin in healthy postmenopausal women: principal results from the Women's Health Initiative randomized controlled trial. JAMA 2002;288:321-3
-
(2002)
JAMA
, vol.288
, pp. 321-323
-
-
Rossouw, J.E.1
Anderson, J.L.2
Prentice, R.L.3
-
6
-
-
50549123220
-
On the treatment of inoperable cases of carcinoma of the mamma: Suggestions for a new method of treatment with illustrative cases
-
Beatson GT. On the treatment of inoperable cases of carcinoma of the mamma: suggestions for a new method of treatment with illustrative cases. Lancet 1896;2:104-7
-
(1896)
Lancet
, vol.2
, pp. 104-107
-
-
Beatson, G.T.1
-
7
-
-
0001733527
-
On oophorectomy in cancer of the breast
-
Boyd S. On oophorectomy in cancer of the breast. BMJ 1900;2:1161-7
-
(1900)
BMJ
, vol.2
, pp. 1161-1167
-
-
Boyd, S.1
-
10
-
-
0035945656
-
-
Clemons M, Goss P. Estrogen and the risk of breast cancer. N Engl J Med 2001;344:276-85. Erratum in: N Engl J Med 2001;344:1804
-
Clemons M, Goss P. Estrogen and the risk of breast cancer. N Engl J Med 2001;344:276-85. Erratum in: N Engl J Med 2001;344:1804
-
-
-
-
11
-
-
0022259725
-
Regulation of epidermal growth factor receptor by estrogen
-
Mukku VR, Stancel GM. Regulation of epidermal growth factor receptor by estrogen. J Biol Chem 1985;260:9820-4
-
(1985)
J Biol Chem
, vol.260
, pp. 9820-9824
-
-
Mukku, V.R.1
Stancel, G.M.2
-
12
-
-
0033842834
-
Crosstalk between the insulin-like growth factors and estrogens in breast cancer
-
Yee D, Lee AM. Crosstalk between the insulin-like growth factors and estrogens in breast cancer. J Mammary Gland Biol Neoplasia 2000;5:107-15
-
(2000)
J Mammary Gland Biol Neoplasia
, vol.5
, pp. 107-115
-
-
Yee, D.1
Lee, A.M.2
-
13
-
-
0026718269
-
Pregnancy-related factors and risk of breast cancer in a prospective study of 29981 Norwegian women
-
Vatten LJ, Kvinnsland S. Pregnancy-related factors and risk of breast cancer in a prospective study of 29981 Norwegian women. Eur J Cancer 1992;28A:1148-53
-
(1992)
Eur J Cancer
, vol.28 A
, pp. 1148-1153
-
-
Vatten, L.J.1
Kvinnsland, S.2
-
14
-
-
0037434618
-
Selective estrogen-receptor modulators: Mechanisms of action and application to clinical practice
-
Riggs L, Hartmann LC. Selective estrogen-receptor modulators: mechanisms of action and application to clinical practice. N Engl J Med 2003;348:618-29
-
(2003)
N Engl J Med
, vol.348
, pp. 618-629
-
-
Riggs, L.1
Hartmann, L.C.2
-
15
-
-
0032446607
-
The structural basis of estrogen receptor/coactivator recognition and the antagonism of this interaction by tamoxifen
-
Shiau AK, Barstad D, Loria PM, et al. The structural basis of estrogen receptor/coactivator recognition and the antagonism of this interaction by tamoxifen. Cell 1998;95:927-37
-
(1998)
Cell
, vol.95
, pp. 927-937
-
-
Shiau, A.K.1
Barstad, D.2
Loria, P.M.3
-
16
-
-
0030667676
-
Molecular basis of agonism and antagonism in the oestrogen receptor
-
Brzozowski AM, Pike AC, Dauter Z, et al. Molecular basis of agonism and antagonism in the oestrogen receptor. Nature 1997;389:753-8
-
(1997)
Nature
, vol.389
, pp. 753-758
-
-
Brzozowski, A.M.1
Pike, A.C.2
Dauter, Z.3
-
17
-
-
2642544810
-
Estrogen receptor (ER) modulators each induce distinct conformational changes in ERa and ERb
-
Paige LA, Christensen DJ, Gron H, et al. Estrogen receptor (ER) modulators each induce distinct conformational changes in ERa and ERb. Proc Natl Acad Sci USA 1999;96:3999-4004
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 3999-4004
-
-
Paige, L.A.1
Christensen, D.J.2
Gron, H.3
-
18
-
-
0017098034
-
Tamoxifen as an antitumour agent: Oestrogen binding as a predictive test for tumour response
-
Jordan VC, Jaspan T. Tamoxifen as an antitumour agent: oestrogen binding as a predictive test for tumour response. J Endocrinol 1976;68:453-60
-
(1976)
J Endocrinol
, vol.68
, pp. 453-460
-
-
Jordan, V.C.1
Jaspan, T.2
-
19
-
-
0032569831
-
Tamoxifen in the treatment of breast cancer
-
Osborne CK. Tamoxifen in the treatment of breast cancer. N Engl J Med 1998;339:1609-18
-
(1998)
N Engl J Med
, vol.339
, pp. 1609-1618
-
-
Osborne, C.K.1
-
20
-
-
0033549344
-
Tamoxifen in treatment of intraductal breast cancer National Surgical Adjuvant Breast and Bowel Project B-24 randomised controlled trial
-
Fisher B, Dignam J, Wolmark N, et al. Tamoxifen in treatment of intraductal breast cancer National Surgical Adjuvant Breast and Bowel Project B-24 randomised controlled trial. Lancet 1999;353:1993-2000
-
(1999)
Lancet
, vol.353
, pp. 1993-2000
-
-
Fisher, B.1
Dignam, J.2
Wolmark, N.3
-
21
-
-
0024506261
-
A randomized clinical trial evaluating tamoxifen in the treatment of patients with node-negative breast cancer who have estrogen-receptor-positive tumors
-
Fisher B, Costantino J, Redmond C, et al. A randomized clinical trial evaluating tamoxifen in the treatment of patients with node-negative breast cancer who have estrogen-receptor-positive tumors. N Engl J Med 1989;320:479-84
-
(1989)
N Engl J Med
, vol.320
, pp. 479-484
-
-
Fisher, B.1
Costantino, J.2
Redmond, C.3
-
22
-
-
0032537396
-
Tamoxifen for early breast cancer: An overview of the randomised trials
-
Early Breast Cancer Trialists' Collaborative Group
-
Early Breast Cancer Trialists' Collaborative Group. Tamoxifen for early breast cancer: an overview of the randomised trials. Lancet 1998;351:1451-67
-
(1998)
Lancet
, vol.351
, pp. 1451-1467
-
-
-
23
-
-
0017078344
-
Effect of tamoxifen (ICI 46, 474) on initiation and growth of DMBA-induced rat mammary carcinomata
-
Jordan VC. Effect of tamoxifen (ICI 46, 474) on initiation and growth of DMBA-induced rat mammary carcinomata. Eur J Cancer 1976;12:419-24
-
(1976)
Eur J Cancer
, vol.12
, pp. 419-424
-
-
Jordan, V.C.1
-
24
-
-
0032537990
-
Tamoxifen for prevention of breast cancer: Report of the National Surgical Adjuvant Breast and Bowel Project P-1 Study
-
Fisher B, Costantino JP, Wickerham DL, et al. Tamoxifen for prevention of breast cancer: report of the National Surgical Adjuvant Breast and Bowel Project P-1 Study. J Natl Cancer Inst 1998;90:1371-88
-
(1998)
J Natl Cancer Inst
, vol.90
, pp. 1371-1388
-
-
Fisher, B.1
Costantino, J.P.2
Wickerham, D.L.3
-
25
-
-
0032508293
-
Prevention of breast cancer with tamoxifen: Preliminary findings from the Italian randomised trial among hysterectomised women. Italian Tamoxifen Prevention Study
-
Veronesi U, Maisonneuve P, Costa A, et al. Prevention of breast cancer with tamoxifen: preliminary findings from the Italian randomised trial among hysterectomised women. Italian Tamoxifen Prevention Study. Lancet 1998;352:93-7
-
(1998)
Lancet
, vol.352
, pp. 93-97
-
-
Veronesi, U.1
Maisonneuve, P.2
Costa, A.3
-
26
-
-
0032508294
-
Interim analysis of the incidence of breast cancer in the Royal Marsden Hospital tamoxifen randomised chemoprevention trial
-
Powles T, Eeles R, Ashley S, et al. Interim analysis of the incidence of breast cancer in the Royal Marsden Hospital tamoxifen randomised chemoprevention trial. Lancet 1998;352:98-101
-
(1998)
Lancet
, vol.352
, pp. 98-101
-
-
Powles, T.1
Eeles, R.2
Ashley, S.3
-
27
-
-
0037197090
-
Tamoxifen for breast cancer among hysterectomised women
-
Veronesi U, Maisonneuve P, Sacchini V, et al. Tamoxifen for breast cancer among hysterectomised women. Lancet 2002;359:1122-4
-
(2002)
Lancet
, vol.359
, pp. 1122-1124
-
-
Veronesi, U.1
Maisonneuve, P.2
Sacchini, V.3
-
28
-
-
80052059849
-
First results from the International Breast Cancer Intervention Study (IBIS-I): A randomised prevention trial
-
Cuzick J, Forbes J, Edwards R, et al. First results from the International Breast Cancer Intervention Study (IBIS-I): a randomised prevention trial. Lancet 2002;360:817-24
-
(2002)
Lancet
, vol.360
, pp. 817-824
-
-
Cuzick, J.1
Forbes, J.2
Edwards, R.3
-
29
-
-
27944492407
-
Tamoxifen for the prevention of breast cancer: Current status of the National Surgical Adjuvant Breast and Bowel Project P-1 study
-
Fisher B, Costantino JP, Wickerham DL, et al. Tamoxifen for the prevention of breast cancer: current status of the National Surgical Adjuvant Breast and Bowel Project P-1 study. J Natl Cancer Inst 2005;97:1652-62
-
(2005)
J Natl Cancer Inst
, vol.97
, pp. 1652-1662
-
-
Fisher, B.1
Costantino, J.P.2
Wickerham, D.L.3
-
30
-
-
33847793068
-
Long-term results of tamoxifen prophylaxis for breast cancer - 96-month follow-up of the randomized IBIS-I trial
-
Cuzick J, Forbes JF, Sestak I, et al. Long-term results of tamoxifen prophylaxis for breast cancer - 96-month follow-up of the randomized IBIS-I trial. J Natl Cancer Inst 2007;99:272-82
-
(2007)
J Natl Cancer Inst
, vol.99
, pp. 272-282
-
-
Cuzick, J.1
Forbes, J.F.2
Sestak, I.3
-
31
-
-
34249732092
-
Tamoxifen for the prevention of breast cancer: Late results of the Italian Randomized Tamoxifen Prevention Trial among women with hysterectomy
-
Veronesi U, Maisonneuve P, Rotmensz N, et al. Tamoxifen for the prevention of breast cancer: late results of the Italian Randomized Tamoxifen Prevention Trial among women with hysterectomy. J Natl Cancer Inst 2007;99:727-37
-
(2007)
J Natl Cancer Inst
, vol.99
, pp. 727-737
-
-
Veronesi, U.1
Maisonneuve, P.2
Rotmensz, N.3
-
32
-
-
33847773775
-
Twenty-year follow-up of the Royal Marsden randomized, double-blinded tamoxifen breast cancer prevention trial
-
Powles TJ, Ashley S, Tidy A, et al. Twenty-year follow-up of the Royal Marsden randomized, double-blinded tamoxifen breast cancer prevention trial. J Natl Cancer Inst 2007;99:283-90
-
(2007)
J Natl Cancer Inst
, vol.99
, pp. 283-290
-
-
Powles, T.J.1
Ashley, S.2
Tidy, A.3
-
33
-
-
0037464769
-
Overview of the main outcomes in breast-cancer prevention trials
-
Cuzick J, Powles T, Veronesi U, et al. Overview of the main outcomes in breast-cancer prevention trials. Lancet 2003;361:296-300
-
(2003)
Lancet
, vol.361
, pp. 296-300
-
-
Cuzick, J.1
Powles, T.2
Veronesi, U.3
-
34
-
-
0020582094
-
Effects of a new antiestrogen, keoxifene (LY156758), on growth of carcinogen-induced mammary tumors and on LH and prolactin levels
-
Clemens JA, Bennett DR, Black LJ, Jones CD. Effects of a new antiestrogen, keoxifene (LY156758), on growth of carcinogen-induced mammary tumors and on LH and prolactin levels. Life Sci 1983;32:2869-75
-
(1983)
Life Sci
, vol.32
, pp. 2869-2875
-
-
Clemens, J.A.1
Bennett, D.R.2
Black, L.J.3
Jones, C.D.4
-
35
-
-
33646473146
-
Evaluation of ligand selectivity using reporter cell lines stably expressing estrogen receptor alpha or beta
-
Escande A, Pillon A, Servant N, et al. Evaluation of ligand selectivity using reporter cell lines stably expressing estrogen receptor alpha or beta. Biochem Pharmacol 2006;71:1459-69
-
(2006)
Biochem Pharmacol
, vol.71
, pp. 1459-1469
-
-
Escande, A.1
Pillon, A.2
Servant, N.3
-
36
-
-
0345567604
-
Molecular determinants of tissue selectivity in estrogen receptor modulators
-
Grese TA, Sluka JP, Bryant HU, et al. Molecular determinants of tissue selectivity in estrogen receptor modulators. Proc Natl Acad Sci USA 1997;94:14105-10
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 14105-14110
-
-
Grese, T.A.1
Sluka, J.P.2
Bryant, H.U.3
-
37
-
-
3242732349
-
Role of raloxifene in breast cancer prevention in postmenopausal women: Clinical evidence and potential mechanisms of action
-
Sporne MB, Dowsett SA, Mershon J, Bryant HU. Role of raloxifene in breast cancer prevention in postmenopausal women: clinical evidence and potential mechanisms of action. Clin Ther 2004;26:830-40
-
(2004)
Clin Ther
, vol.26
, pp. 830-840
-
-
Sporne, M.B.1
Dowsett, S.A.2
Mershon, J.3
Bryant, H.U.4
-
38
-
-
0024210084
-
Differential regulation of growth and invasiveness of MCF-7 breast cancer cells by antiestrogens
-
Thompson EW, Reich R, Shima TB, et al. Differential regulation of growth and invasiveness of MCF-7 breast cancer cells by antiestrogens. Cancer Res 1988;48:6764-8
-
(1988)
Cancer Res
, vol.48
, pp. 6764-6768
-
-
Thompson, E.W.1
Reich, R.2
Shima, T.B.3
-
39
-
-
0033005354
-
Influence of antiestrogens on the invasiveness and laminin attachment of breast cancer cells
-
Rajah TT, Pento JT. Influence of antiestrogens on the invasiveness and laminin attachment of breast cancer cells. Cancer Invest 1999;17:10-8
-
(1999)
Cancer Invest
, vol.17
, pp. 10-18
-
-
Rajah, T.T.1
Pento, J.T.2
-
40
-
-
44949143674
-
Anti-growth factor activities of benzothiophenes in breast cancer cells
-
2002 Apr. Contract No.:00251
-
Fries G, Chalbos D, Vignon F. Anti-growth factor activities of benzothiophenes in breast cancer cells. Lilly Nonclinical Study Report. 2002 Apr. Contract No.:00251
-
Lilly Nonclinical Study Report
-
-
Fries, G.1
Chalbos, D.2
Vignon, F.3
-
41
-
-
0001536503
-
Distinct effects of selective estrogen receptor modulators on estrogen dependent and estrogen independent human breast cancer cell proliferation
-
Short LL, Glasebrook AL, Adrian MD, et al. Distinct effects of selective estrogen receptor modulators on estrogen dependent and estrogen independent human breast cancer cell proliferation. J Bone Miner Res 1996;1(1):5482
-
(1996)
J Bone Miner Res
, vol.1
, Issue.1
, pp. 5482
-
-
Short, L.L.1
Glasebrook, A.L.2
Adrian, M.D.3
-
42
-
-
0032081174
-
The selective estrogen receptor modulator, raloxifene: An overview on nonclinical pharmacology and reproductive and developmental testing
-
Buelke-Sam J, Bryant HU, Francio PC. The selective estrogen receptor modulator, raloxifene: an overview on nonclinical pharmacology and reproductive and developmental testing. Reprod Toxicol 1998;12:217-21
-
(1998)
Reprod Toxicol
, vol.12
, pp. 217-221
-
-
Buelke-Sam, J.1
Bryant, H.U.2
Francio, P.C.3
-
44
-
-
13344259303
-
Chemoprevention of mammary carcinogenesis in the rat: Combined use of raloxifene and 9-cis-retinoic acid
-
Anzano MA, Peer CW, Smith JM, et al. Chemoprevention of mammary carcinogenesis in the rat: Combined use of raloxifene and 9-cis-retinoic acid. J Natl Cancer Inst 1996;88:123-5
-
(1996)
J Natl Cancer Inst
, vol.88
, pp. 123-125
-
-
Anzano, M.A.1
Peer, C.W.2
Smith, J.M.3
-
45
-
-
0034878698
-
Preventive effects of raloxifene and melatonin in N-methyl-N-nitrosourea-induced mammary carcinogenesis in female rats
-
Kubatka P, Bojkova B, Kaficka K, et al. Preventive effects of raloxifene and melatonin in N-methyl-N-nitrosourea-induced mammary carcinogenesis in female rats. Neoplasma 2001;48:313-9
-
(2001)
Neoplasma
, vol.48
, pp. 313-319
-
-
Kubatka, P.1
Bojkova, B.2
Kaficka, K.3
-
46
-
-
0023229345
-
Antitumor actions of keoxifene and tamoxifen in the N-nitrosomethylurea-induced rat mammary carcinoma model
-
Gottardis MM, Jordan VC. Antitumor actions of keoxifene and tamoxifen in the N-nitrosomethylurea-induced rat mammary carcinoma model. Cancer Res 1987;47:4020-4
-
(1987)
Cancer Res
, vol.47
, pp. 4020-4024
-
-
Gottardis, M.M.1
Jordan, V.C.2
-
47
-
-
0021038981
-
Antioestrogenic and antitumour activities of a series of non-steroidal antioestrogens
-
Wakeling AE, Valcaccia B. Antioestrogenic and antitumour activities of a series of non-steroidal antioestrogens. J Endocrinol 1983;99:455-64
-
(1983)
J Endocrinol
, vol.99
, pp. 455-464
-
-
Wakeling, A.E.1
Valcaccia, B.2
-
48
-
-
0021958425
-
Effect of estrogens and antiestrogens on growths of human breast cancer cells in athymic nude mice
-
Osborne CK, Hobbs K, Clark GM. Effect of estrogens and antiestrogens on growths of human breast cancer cells in athymic nude mice. Cancer Res 1985;45:584-90
-
(1985)
Cancer Res
, vol.45
, pp. 584-590
-
-
Osborne, C.K.1
Hobbs, K.2
Clark, G.M.3
-
49
-
-
0036744793
-
Selective estrogen receptor modulators
-
Bryant HU. Selective estrogen receptor modulators. Rev Endocr Metab Dis 2002;3:231-41
-
(2002)
Rev Endocr Metab Dis
, vol.3
, pp. 231-241
-
-
Bryant, H.U.1
-
50
-
-
0033304703
-
Tamoxifen, raloxifene, and the prevention of breast cancer
-
Jordan VC, Morrow M. Tamoxifen, raloxifene, and the prevention of breast cancer. Endocr Rev 1999;20:253-78
-
(1999)
Endocr Rev
, vol.20
, pp. 253-278
-
-
Jordan, V.C.1
Morrow, M.2
-
51
-
-
0028167482
-
Raloxifene (LY139481 HCI) prevents bone loss and reduces serum cholesterol without causing uterine hypertrophy in ovariectomized rats
-
Black LJ, Sato M, Rowley ER, et al. Raloxifene (LY139481 HCI) prevents bone loss and reduces serum cholesterol without causing uterine hypertrophy in ovariectomized rats. J Clin Invest 1994;93:63-9
-
(1994)
J Clin Invest
, vol.93
, pp. 63-69
-
-
Black, L.J.1
Sato, M.2
Rowley, E.R.3
-
52
-
-
0029994748
-
-
Sato M, Rippy MK, Bryant HU. Raloxifene, tamoxifen, nafoxidine, or estrogen effects on reproductive and nonreproductive tissues in ovariectomized rats. FASEB J 1996;10:905-12
-
Sato M, Rippy MK, Bryant HU. Raloxifene, tamoxifen, nafoxidine, or estrogen effects on reproductive and nonreproductive tissues in ovariectomized rats. FASEB J 1996;10:905-12
-
-
-
-
53
-
-
0001883015
-
Raloxifene is a tissue-specific anti-estrogen that blocks tamoxifen or estrogen stimulate uterotrophic effects
-
Fuchs-Young R, Magee DE, et al. Raloxifene is a tissue-specific anti-estrogen that blocks tamoxifen or estrogen stimulate uterotrophic effects. Endocrinology 1995;136:S57
-
(1995)
Endocrinology
, vol.136
-
-
Fuchs-Young, R.1
Magee, D.E.2
-
54
-
-
0023683229
-
Phase II evaluation of LY156758 in metastatic breast cancer
-
Buzdar AU, Marcus C, Holmes F, et al. Phase II evaluation of LY156758 in metastatic breast cancer. Oncology 1988;45:344-5
-
(1988)
Oncology
, vol.45
, pp. 344-345
-
-
Buzdar, A.U.1
Marcus, C.2
Holmes, F.3
-
55
-
-
0034193122
-
Effects of high dose raloxifene in selected patients with advanced breast carcinoma
-
Gradishar W, Glusman J, Lu Y, et al. Effects of high dose raloxifene in selected patients with advanced breast carcinoma. Cancer 2000;88:2047-53
-
(2000)
Cancer
, vol.88
, pp. 2047-2053
-
-
Gradishar, W.1
Glusman, J.2
Lu, Y.3
-
56
-
-
0029741919
-
Aromatase inhibitors and breast cancer
-
Brodie AM, Njar VC. Aromatase inhibitors and breast cancer. Semin Oncol 1996;23:10-20
-
(1996)
Semin Oncol
, vol.23
, pp. 10-20
-
-
Brodie, A.M.1
Njar, V.C.2
-
57
-
-
0031299490
-
Pure antiestrogens as a new therapy for breast cancer
-
England GM, Jordan VC. Pure antiestrogens as a new therapy for breast cancer. Oncol Res 1997;9:397-402
-
(1997)
Oncol Res
, vol.9
, pp. 397-402
-
-
England, G.M.1
Jordan, V.C.2
-
58
-
-
10944253019
-
Chemopreventive effect of the aromatase inactivator exemestane combined with the antiestrogen raloxifene in the dimethylbenzanthracene (DMBA)-induced mammary tumors in rats
-
di Salle E, Geroni C, Lamparelli M, et al. Chemopreventive effect of the aromatase inactivator exemestane combined with the antiestrogen raloxifene in the dimethylbenzanthracene (DMBA)-induced mammary tumors in rats. Am Soc Clin Oncol 2002;21:117a
-
(2002)
Am Soc Clin Oncol
, vol.21
-
-
di Salle, E.1
Geroni, C.2
Lamparelli, M.3
-
59
-
-
43449105987
-
Pharmacokinetics and tolerability of exemestane in combination with raloxifene in postmenopausal women with a history of breast cancer
-
Epub ahead of print
-
Traina TA, Poggesi I, Robson M, et al. Pharmacokinetics and tolerability of exemestane in combination with raloxifene in postmenopausal women with a history of breast cancer. Breast Cancer Res Treat 2007 [Epub ahead of print]
-
(2007)
Breast Cancer Res Treat
-
-
Traina, T.A.1
Poggesi, I.2
Robson, M.3
-
60
-
-
0028853923
-
Estrogen deprivation causes estradiol hypersensitivity in human breast cancer cells
-
Masamura S, Santner SJ, Heitjan DF, et al. Estrogen deprivation causes estradiol hypersensitivity in human breast cancer cells. J Clin Endocrinol Metab 1995;80:2918-25
-
(1995)
J Clin Endocrinol Metab
, vol.80
, pp. 2918-2925
-
-
Masamura, S.1
Santner, S.J.2
Heitjan, D.F.3
-
61
-
-
0037157603
-
-
Baum M, Budzar AU, Cuzick J, et al. Anastrozole alone or in combination with tamoxifen versus tamoxifen alone for adjuvant treatment of postmenopausal women with early breast cancer: first results of the ATAC randomised trial. Lancet 2002;359:2131-9. Erratum in: Lancet 2002;360:1520
-
Baum M, Budzar AU, Cuzick J, et al. Anastrozole alone or in combination with tamoxifen versus tamoxifen alone for adjuvant treatment of postmenopausal women with early breast cancer: first results of the ATAC randomised trial. Lancet 2002;359:2131-9. Erratum in: Lancet 2002;360:1520
-
-
-
-
62
-
-
0034846422
-
Effect of raloxifene on breast cancer cell Ki67 and apoptosis: A double-blind, placebo-controlled, randomized clinical trial in postmenopausal patients
-
Dowsett M, Bundred NJ, Decensi A, et al. Effect of raloxifene on breast cancer cell Ki67 and apoptosis: a double-blind, placebo-controlled, randomized clinical trial in postmenopausal patients. Cancer Epidemiol Biomarkers Prev 2001;10:961-6
-
(2001)
Cancer Epidemiol Biomarkers Prev
, vol.10
, pp. 961-966
-
-
Dowsett, M.1
Bundred, N.J.2
Decensi, A.3
-
63
-
-
0030664688
-
Effects of raloxifene on bone mineral density, serum cholesterol concentrations, and uterine endometrium in postmenopausal women
-
Delmas PD, Bjarnason NH, Mitlak BH, et al. Effects of raloxifene on bone mineral density, serum cholesterol concentrations, and uterine endometrium in postmenopausal women. N Engl J Med 1997;337:1641-7
-
(1997)
N Engl J Med
, vol.337
, pp. 1641-1647
-
-
Delmas, P.D.1
Bjarnason, N.H.2
Mitlak, B.H.3
-
64
-
-
0033581212
-
-
Ettinger B, Black DM, Mitlak BH, et al. Reduction of vertebral fracture risk in postmenopausal women with osteoporosis treated with raloxifene: results from a 3-year randomized clinical trial. Multiple Outcomes of Raloxifene Evaluation (MORE) Investigators. JAMA 1999;282:637-45. Erratum in: JAMA 1999;282:2124
-
Ettinger B, Black DM, Mitlak BH, et al. Reduction of vertebral fracture risk in postmenopausal women with osteoporosis treated with raloxifene: results from a 3-year randomized clinical trial. Multiple Outcomes of Raloxifene Evaluation (MORE) Investigators. JAMA 1999;282:637-45. Erratum in: JAMA 1999;282:2124
-
-
-
-
66
-
-
0033575083
-
-
Cummings SR, Eckert S, Krueger KA, et al. The effect of raloxifene on risk of breast cancer in postmenopausal women: results from the MORE randomized trial. Multiple Outcomes of Raloxifene Evaluation. JAMA 1999;281: 2189-97. Erratum in: JAMA 1999;281:2124
-
Cummings SR, Eckert S, Krueger KA, et al. The effect of raloxifene on risk of breast cancer in postmenopausal women: results from the MORE randomized trial. Multiple Outcomes of Raloxifene Evaluation. JAMA 1999;281: 2189-97. Erratum in: JAMA 1999;281:2124
-
-
-
-
67
-
-
0035120523
-
-
Cauley JA, Norton L, Lippman ME, et al. Continued breast cancer risk reduction in postmenopausal women treated with raloxifene: 4-year results from the MORE trial. Multiple outcomes of raloxifene evaluation. Breast Cancer Res Treat 2001;65:125-34. Erratum in: Breast Cancer Res Treat 2001;67:191
-
Cauley JA, Norton L, Lippman ME, et al. Continued breast cancer risk reduction in postmenopausal women treated with raloxifene: 4-year results from the MORE trial. Multiple outcomes of raloxifene evaluation. Breast Cancer Res Treat 2001;65:125-34. Erratum in: Breast Cancer Res Treat 2001;67:191
-
-
-
-
68
-
-
0035875830
-
-
Lippman ME, Krueger KA, Eckert S, et al. Indicators of lifetime estrogen exposure: effect on breast cancer incidence and interaction with raloxifene therapy in the multiple outcomes of raloxifene evaluation study participants. J Clin Oncol 2001;19:3111-6. Erratum in: J Clin Oncol 2001;20:1430
-
Lippman ME, Krueger KA, Eckert S, et al. Indicators of lifetime estrogen exposure: effect on breast cancer incidence and interaction with raloxifene therapy in the multiple outcomes of raloxifene evaluation study participants. J Clin Oncol 2001;19:3111-6. Erratum in: J Clin Oncol 2001;20:1430
-
-
-
-
69
-
-
10644283864
-
Continuing outcomes relevant to Evista: Breast cancer incidence in postmenopausal osteoporotic women in a randomized trial of raloxifene
-
Martino S, Cauley JA, Barrett-Connor E, et al. Continuing outcomes relevant to Evista: breast cancer incidence in postmenopausal osteoporotic women in a randomized trial of raloxifene. J Natl Cancer Inst 2004;96:1751-61
-
(2004)
J Natl Cancer Inst
, vol.96
, pp. 1751-1761
-
-
Martino, S.1
Cauley, J.A.2
Barrett-Connor, E.3
-
70
-
-
33749002851
-
Effect of raloxifene on the incidence of invasive breast cancer in postmenopausal women with osteoporosis categorized by breast cancer risk
-
Lippman ME, Cummings SR, Disch DP, et al. Effect of raloxifene on the incidence of invasive breast cancer in postmenopausal women with osteoporosis categorized by breast cancer risk. Clin Cancer Res 2006;12:5242-7
-
(2006)
Clin Cancer Res
, vol.12
, pp. 5242-5247
-
-
Lippman, M.E.1
Cummings, S.R.2
Disch, D.P.3
-
71
-
-
33745876266
-
Effects of raloxifene on cardiovascular events and breast cancer in postmenopausal women
-
Barrett-Connor E, Mosca L, Collins P, et al. Effects of raloxifene on cardiovascular events and breast cancer in postmenopausal women. N Engl J Med 2006;355:125-37
-
(2006)
N Engl J Med
, vol.355
, pp. 125-137
-
-
Barrett-Connor, E.1
Mosca, L.2
Collins, P.3
-
72
-
-
0033714107
-
first-year recruitment efforts set brisk pace for future
-
STAR
-
STAR: first-year recruitment efforts set brisk pace for future. CA Cancer J Clin 2000;50:271-2
-
(2000)
CA Cancer J Clin
, vol.50
, pp. 271-272
-
-
-
73
-
-
0034931645
-
From adjuvant therapy to breast cancer prevention: BCPT and STAR
-
Dunn BK, Ford LG. From adjuvant therapy to breast cancer prevention: BCPT and STAR. Breast J 2001;7:144-57
-
(2001)
Breast J
, vol.7
, pp. 144-157
-
-
Dunn, B.K.1
Ford, L.G.2
-
74
-
-
85136388508
-
-
Vogel VG, Costantino JP, Wickerham DL, et al. Effects of tamoxifen vs raloxifene on the risk of developing invasive breast cancer and other disease outcomes: the NSABP Study of Tamoxifen and Raloxifene (STAR) P-2 trial. JAMA 2006;295:2727-41. Erratum in: JAMA 2006;296:2926 and JAMA 2007;298:973
-
Vogel VG, Costantino JP, Wickerham DL, et al. Effects of tamoxifen vs raloxifene on the risk of developing invasive breast cancer and other disease outcomes: the NSABP Study of Tamoxifen and Raloxifene (STAR) P-2 trial. JAMA 2006;295:2727-41. Erratum in: JAMA 2006;296:2926 and JAMA 2007;298:973
-
-
-
-
75
-
-
0033568691
-
Validation studies for models projecting the risk of invasive and total breast cancer incidence
-
Costantino JP, Gail MH, Pee D, et al. Validation studies for models projecting the risk of invasive and total breast cancer incidence. J Natl Cancer Inst 1999;91:1541-8
-
(1999)
J Natl Cancer Inst
, vol.91
, pp. 1541-1548
-
-
Costantino, J.P.1
Gail, M.H.2
Pee, D.3
-
76
-
-
0034650419
-
Characterization of hot flashes reported by healthy postmenopausal women receiving raloxifene or placebo during osteoporosis prevention trials
-
Cohen FJ, Lu Y. Characterization of hot flashes reported by healthy postmenopausal women receiving raloxifene or placebo during osteoporosis prevention trials. Maturitas 2000;34:65-73
-
(2000)
Maturitas
, vol.34
, pp. 65-73
-
-
Cohen, F.J.1
Lu, Y.2
-
77
-
-
25444486711
-
Safety assessment of raloxifene over eight years in clinical trial setting
-
Martino S, Disch D, Dowsett SA, et al. Safety assessment of raloxifene over eight years in clinical trial setting. Curr Med Res Opin 2005;21:1441-52
-
(2005)
Curr Med Res Opin
, vol.21
, pp. 1441-1452
-
-
Martino, S.1
Disch, D.2
Dowsett, S.A.3
-
78
-
-
0031445808
-
Effects of raloxifrne hydrochloride on the endometrium of postmenopausal women
-
Boss SM, Huster WJ, Neild JA, et al. Effects of raloxifrne hydrochloride on the endometrium of postmenopausal women. Am J Obstet Gynecol 1997;177:1458-64
-
(1997)
Am J Obstet Gynecol
, vol.177
, pp. 1458-1464
-
-
Boss, S.M.1
Huster, W.J.2
Neild, J.A.3
-
79
-
-
0032547326
-
Randomized trial of estrogen plus progestin for secondary prevention of coronary heart disease in postmenopausal women. Heart and Estrogen/Progestin Replacement Study (HERS) Research Group
-
Hulley S, Grady D, Bush T, et al. Randomized trial of estrogen plus progestin for secondary prevention of coronary heart disease in postmenopausal women. Heart and Estrogen/Progestin Replacement Study (HERS) Research Group. JAMA 1998;280:605-13
-
(1998)
JAMA
, vol.280
, pp. 605-613
-
-
Hulley, S.1
Grady, D.2
Bush, T.3
-
80
-
-
0037534909
-
Effect of estrogen plus progestin on stroke in postmenopausal women: The Women's Health Initiative: a randomized trial
-
Wassertheil-Smoller S, Hendrix S, Limacher M, et al. Effect of estrogen plus progestin on stroke in postmenopausal women: the Women's Health Initiative: a randomized trial. JAMA 2003;289:2673-84
-
(2003)
JAMA
, vol.289
, pp. 2673-2684
-
-
Wassertheil-Smoller, S.1
Hendrix, S.2
Limacher, M.3
-
81
-
-
1842557428
-
The role of selective estrogen receptor modulators in the prevention of breast cancer: Comparison of the clinical trials
-
Martino S, Costantino J, McNabb M, et al. The role of selective estrogen receptor modulators in the prevention of breast cancer: comparison of the clinical trials. Oncologist 2004;9:116-25
-
(2004)
Oncologist
, vol.9
, pp. 116-125
-
-
Martino, S.1
Costantino, J.2
McNabb, M.3
-
82
-
-
85136448976
-
-
Land SR, Wickerham DL, Costantino JP, et al. Patient-reported symptoms and quality of life during treatment with tamoxifen or raloxifene for breast cancer prevention: the NSABP Study of Tamoxifen and Raloxifene (STAR) P-2 Trial. JAMA 2006;295:2742-51. Erratum in: JAMA 2007;298:973
-
Land SR, Wickerham DL, Costantino JP, et al. Patient-reported symptoms and quality of life during treatment with tamoxifen or raloxifene for breast cancer prevention: the NSABP Study of Tamoxifen and Raloxifene (STAR) P-2 Trial. JAMA 2006;295:2742-51. Erratum in: JAMA 2007;298:973
-
-
-
-
84
-
-
33845202059
-
Prevention of breast cancer: Current state of the science and future opportunities
-
Uray IP, Brown PH. Prevention of breast cancer: current state of the science and future opportunities. Expert Opin Investig Drugs 2006;15:1583-600
-
(2006)
Expert Opin Investig Drugs
, vol.15
, pp. 1583-1600
-
-
Uray, I.P.1
Brown, P.H.2
-
85
-
-
33745234130
-
Selective estrogen receptor modulators and prevention of invasive breast cancer
-
Gradishar WJ, Cella D. Selective estrogen receptor modulators and prevention of invasive breast cancer. JAMA 2006;295:2784-6
-
(2006)
JAMA
, vol.295
, pp. 2784-2786
-
-
Gradishar, W.J.1
Cella, D.2
-
86
-
-
0037414209
-
Estimates of the number of US women who could benefit from tamoxifen for breast cancer chemoprevention
-
Freedman AN, Graubard BI, Rao SR, et al. Estimates of the number of US women who could benefit from tamoxifen for breast cancer chemoprevention. J Natl Cancer Inst 2003;95:526-32
-
(2003)
J Natl Cancer Inst
, vol.95
, pp. 526-532
-
-
Freedman, A.N.1
Graubard, B.I.2
Rao, S.R.3
-
87
-
-
33745683516
-
Progress in chemoprevention drug development: The promise of molecular biomarkers for prevention of intraepithelial neoplasia and cancer: a plan to move forward
-
Kelloff GJ, Lippman SM, Dannenberg AJ, et al. Progress in chemoprevention drug development: the promise of molecular biomarkers for prevention of intraepithelial neoplasia and cancer: a plan to move forward. Clin Cancer Res 2006;12:3661-97
-
(2006)
Clin Cancer Res
, vol.12
, pp. 3661-3697
-
-
Kelloff, G.J.1
Lippman, S.M.2
Dannenberg, A.J.3
-
88
-
-
0642375461
-
-
Cuzick J. Aromatase inhibitors in prevention: data from the ATAC (arimidex, tamoxifen alone or in combination) trial and the design of IBIS-II (the second International Breast Cancer Intervention Study). Recent results. Cancer Res 2003;163:96-103
-
Cuzick J. Aromatase inhibitors in prevention: data from the ATAC (arimidex, tamoxifen alone or in combination) trial and the design of IBIS-II (the second International Breast Cancer Intervention Study). Recent results. Cancer Res 2003;163:96-103
-
-
-
-
89
-
-
33746455931
-
Effect of an aromatase inhibitor on BMD and bone turnover markers: 2-year results of the Anastrozole, Tamoxifen, Alone or in Combination (ATAC) trial 18233230
-
Eastell R, Hannon RA, Cuzick J, et al. Effect of an aromatase inhibitor on BMD and bone turnover markers: 2-year results of the Anastrozole, Tamoxifen, Alone or in Combination (ATAC) trial 18233230. J Bone Miner Res 2006;21:1215-23
-
(2006)
J Bone Miner Res
, vol.21
, pp. 1215-1223
-
-
Eastell, R.1
Hannon, R.A.2
Cuzick, J.3
-
91
-
-
34548539122
-
Aromatase inhibitors and arthralgias: A new frontier in symptom management for breast cancer survivals
-
Burstein HJ, Winer EP. Aromatase inhibitors and arthralgias: a new frontier in symptom management for breast cancer survivals. J Clin Oncol 2007;25:3797-9
-
(2007)
J Clin Oncol
, vol.25
, pp. 3797-3799
-
-
Burstein, H.J.1
Winer, E.P.2
-
92
-
-
33947714587
-
-
Jordan VC. SERMs: meeting the promise of multifunctional medicines. J Natl Cancer Inst 2007;99:350-6
-
Jordan VC. SERMs: meeting the promise of multifunctional medicines. J Natl Cancer Inst 2007;99:350-6
-
-
-
-
93
-
-
44949083187
-
-
NDA#022042. Available from: http://www.fda.gov/default.htm
-
NDA#022042. Available from: http://www.fda.gov/default.htm
-
-
-
-
94
-
-
33749573615
-
Effect of raloxifene on bone mineral density in premenopausal women at increased risk of breast cancer
-
Eng-Wong J, Reynolds JC, Venzon D, et al. Effect of raloxifene on bone mineral density in premenopausal women at increased risk of breast cancer. J Clin Endocrinol Metab 2006;91:3941-6
-
(2006)
J Clin Endocrinol Metab
, vol.91
, pp. 3941-3946
-
-
Eng-Wong, J.1
Reynolds, J.C.2
Venzon, D.3
-
95
-
-
33750508737
-
Optimising endocrine approaches for the chemoprevention of breast cancer beyond the Study of Tamoxifen and Raloxifene (STAR) trial
-
Jordan VC. Optimising endocrine approaches for the chemoprevention of breast cancer beyond the Study of Tamoxifen and Raloxifene (STAR) trial. Eur J Cancer 2006;42:2909-13
-
(2006)
Eur J Cancer
, vol.42
, pp. 2909-2913
-
-
Jordan, V.C.1
-
96
-
-
0033520748
-
Weighing the risks and benefits of tamoxifen treatment for preventing breast cancer
-
Gail MH, Castantino JP, Bryant J, et al. Weighing the risks and benefits of tamoxifen treatment for preventing breast cancer. J Natl Cancer Inst 1999;91:1829-46
-
(1999)
J Natl Cancer Inst
, vol.91
, pp. 1829-1846
-
-
Gail, M.H.1
Castantino, J.P.2
Bryant, J.3
-
97
-
-
0034467033
-
Future possibilities in the prevention of breast cancer: Role of genetic variation in breast cancer prevention
-
Feigelson HS, Henderson BE. Future possibilities in the prevention of breast cancer: role of genetic variation in breast cancer prevention. Breast Cancer Res 2000;2:277-82
-
(2000)
Breast Cancer Res
, vol.2
, pp. 277-282
-
-
Feigelson, H.S.1
Henderson, B.E.2
-
98
-
-
34249055240
-
Selective estrogen receptor modulators for postmenopausal osteoporosis: Current state of development
-
Gennari L, Merlotti D, Valleggi F, et al. Selective estrogen receptor modulators for postmenopausal osteoporosis: current state of development. Drugs Aging 2007;24:361-79
-
(2007)
Drugs Aging
, vol.24
, pp. 361-379
-
-
Gennari, L.1
Merlotti, D.2
Valleggi, F.3
|