메뉴 건너뛰기




Volumn 25, Issue 3, 2009, Pages 139-152

The mechanisms of brain ischemic insult and potential protective interventions

Author keywords

Brain ischemia; Calcium toxicity; Endoplasmic reticulum stress; Glutamate receptors; Neuroprotection

Indexed keywords

4 AMINOBUTYRIC ACID; AMPA RECEPTOR; BRAIN DERIVED NEUROTROPHIC FACTOR; CALCIUM; FREE RADICAL; GLUTAMATE RECEPTOR; GLUTAMIC ACID; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1; INTERLEUKIN 6; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NITRIC OXIDE; TUMOR NECROSIS FACTOR ALPHA;

EID: 67650735624     PISSN: 16737067     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12264-009-0104-3     Document Type: Short Survey
Times cited : (25)

References (97)
  • 1
    • 0037224703 scopus 로고    scopus 로고
    • Adventures in the pathophysiology of brain ischemia: Penumbra, gene expression, neuroprotection: The 2002 Thomas Willis lecture
    • DOI 10.1161/01.STR.0000048846.09677.62
    • M.D. Ginsberg 2003 Adventures in the pathophysiology of brain ischemia: penumbra, gene expression, neuroprotection: the 2002 Thomas Willis Lecture Stroke 34 1 214 223 (Pubitemid 36070826)
    • (2003) Stroke , vol.34 , Issue.1 , pp. 214-223
    • Ginsberg, M.D.1
  • 2
    • 0035186833 scopus 로고    scopus 로고
    • Penumbral probability thresholds of cortical flumazenil binding and blood flow predicting tissue outcome in patients with cerebral ischaemia
    • W.D. Heiss L.W. Kracht A. Thiel M. Grond G. Pawlik 2001 Penumbral probability thresholds of cortical flumazenil binding and blood flow predicting tissue outcome in patients with cerebral ischaemia Brain 124 Pt1 20 29 (Pubitemid 32055986)
    • (2001) Brain , vol.124 , Issue.1 , pp. 20-29
    • Heiss, W.-D.1    Kracht, L.W.2    Thiel, A.3    Grond, M.4    Pawlik, G.5
  • 3
    • 33845547792 scopus 로고    scopus 로고
    • Pathophysiology and therapy of experimental stroke
    • K.A. Hossmann 2006 Pathophysiology and therapy of experimental stroke Cell Mol Neurobiol 26 7-8 1057 1083
    • (2006) Cell Mol Neurobiol , vol.26 , Issue.78 , pp. 1057-1083
    • Hossmann, K.A.1
  • 4
    • 0031546022 scopus 로고    scopus 로고
    • The new language of cerebral ischemia
    • M.D. Ginsberg 1997 The New Language of Cerebral Ischemia Am J Neuroradiol 18 8 1435 1445 (Pubitemid 30413958)
    • (1997) American Journal of Neuroradiology , vol.18 , Issue.8 , pp. 1435-1445
    • Ginsberg, M.D.1
  • 5
    • 33947628060 scopus 로고    scopus 로고
    • Molecular targets in cerebral ischemia for developing novel therapeutics
    • DOI 10.1016/j.brainresrev.2006.11.003, PII S0165017306001172
    • S.L. Mehta N. Manhas R. Raghubir 2007 Molecular targets in cerebral ischemia for developing novel therapeutics Brain Res Rev 54 1 34 66 (Pubitemid 46498164)
    • (2007) Brain Research Reviews , vol.54 , Issue.1 , pp. 34-66
    • Mehta, S.L.1    Manhas, N.2    Raghubir, R.3
  • 6
    • 0031953601 scopus 로고    scopus 로고
    • Calcium in ischemic cell death
    • T. Kristián B.K. Siesjö 1998 Calcium in ischemic cell death Stroke 29 3 705 718 (Pubitemid 28145802)
    • (1998) Stroke , vol.29 , Issue.3 , pp. 705-718
    • Kristian, T.1    Siesjo, B.K.2
  • 7
    • 55749108180 scopus 로고    scopus 로고
    • Differential roles of NMDA receptor subtypes in ischemic neuronal cell death and ischemic tolerance
    • M. Chen T.J. Lu X.J. Chen Y. Zhou Q. Chen X.Y. Feng 2008 Differential roles of NMDA receptor subtypes in ischemic neuronal cell death and ischemic tolerance Stroke 39 11 3042 3048
    • (2008) Stroke , vol.39 , Issue.11 , pp. 3042-3048
    • Chen, M.1    Lu, T.J.2    Chen, X.J.3    Zhou, Y.4    Chen, Q.5    Feng, X.Y.6
  • 8
    • 0027926582 scopus 로고
    • Cell signalling. A tale of two messengers
    • M.J. Berridge 1993 Cell signalling. A tale of two messengers Nature 365 6445 388 389
    • (1993) Nature , vol.365 , Issue.6445 , pp. 388-389
    • Berridge, M.J.1
  • 9
    • 0029851855 scopus 로고    scopus 로고
    • Disturbances of calcium homeostasis within the endoplasmic reticulum may contribute to the development of ischemic-cell damage
    • DOI 10.1016/S0306-9877(96)90068-7
    • W. Paschen 1996 Disturbances of calcium homeostasis within the endoplasmic reticulum may contribute to the development of ischemic-cell damage Med Hypotheses 47 4 283 288 (Pubitemid 26354403)
    • (1996) Medical Hypotheses , vol.47 , Issue.4 , pp. 283-288
    • Paschen, W.1
  • 10
    • 0037449409 scopus 로고    scopus 로고
    • Delayed effect of administration of COX-2 inhibitor in mice with acute cerebral ischemia
    • DOI 10.1016/S0006-8993(02)03805-2, PII S0006899302038052
    • K. Sugimoto C. Iadecola 2003 Delayed effect of administration of COX-2 inhibitor in mice with acute cerebral ischemia Brain Res 960 1-2 273 276 (Pubitemid 36044587)
    • (2003) Brain Research , vol.960 , Issue.1-2 , pp. 273-276
    • Sugimoto, K.1    Iadecola, C.2
  • 12
    • 46549089415 scopus 로고    scopus 로고
    • Isoflurane preconditioning reduces mouse microglial activation and injury induced by lipopolysaccharide and interferon-gamma
    • X. Xu J.A. Kim Z. Zuo 2008 Isoflurane preconditioning reduces mouse microglial activation and injury induced by lipopolysaccharide and interferon-gamma Neuroscience 154 3 1002 1008
    • (2008) Neuroscience , vol.154 , Issue.3 , pp. 1002-1008
    • Xu, X.1    Kim, J.A.2    Zuo, Z.3
  • 13
    • 0035876916 scopus 로고    scopus 로고
    • Minocycline provides neuroprotection against N-methyl-D-aspartate neurotoxicity by inhibiting microglia
    • T.M. Tikka J.E. Koistinaho 2001 Minocycline provides neuroprotection against N-methyl-D-aspartate neurotoxicity by inhibiting microglia J Immunol 166 12 7527 7533 (Pubitemid 32525632)
    • (2001) Journal of Immunology , vol.166 , Issue.12 , pp. 7527-7533
    • Tikka, T.M.1    Koistinaho, J.E.2
  • 14
    • 1842587600 scopus 로고    scopus 로고
    • Astrocyte influences on ischemic neuronal-death
    • DOI 10.2174/1566524043479185
    • R.A. Swanson W. Ying T.M. Kauppinen 2004 Astrocyte influences on ischemic neuronal death Curr Mol Med 4 2 193 205 (Pubitemid 38425914)
    • (2004) Current Molecular Medicine , vol.4 , Issue.2 , pp. 193-205
    • Swanson, R.A.1    Ying, W.2    Kauppinen, T.M.3
  • 15
    • 24644487812 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress response and neurodegeneration
    • DOI 10.1016/j.ceca.2005.06.019, PII S0143416005001065
    • W. Paschen T. Mengesdorf 2005 Endoplasmic reticulum stress response and neurodegeneration Cell Calcium 38 3-4 409 415 (Pubitemid 41283279)
    • (2005) Cell Calcium , vol.38 , Issue.3-4 SPEC. ISS. , pp. 409-415
    • Paschen, W.1    Mengesdorf, T.2
  • 16
    • 0030825675 scopus 로고    scopus 로고
    • Release and sequestration of calcium by ryanodine-sensitive stores in rat hippocampal neurones
    • DOI 10.1111/j.1469-7793.1997.013bl.x
    • O. Garaschuk Y. Yaari A. Konnerth 1997 Release and sequestration of calcium by ryanodine-sensitive stores in rat hippocampal neurones J Physiol 502 Pt1 13 30 (Pubitemid 27322973)
    • (1997) Journal of Physiology , vol.502 , Issue.1 , pp. 13-30
    • Garaschuk, O.1    Yaari, Y.2    Konnerth, A.3
  • 17
    • 12944314765 scopus 로고    scopus 로고
    • Physiology and pathophysiology of the calcium store in the endoplasmic reticulum of neurons
    • DOI 10.1152/physrev.00004.2004
    • A. Verkhratsky 2005 Physiology and pathophysiology of the calcium store in the endoplasmic reticulum of neurons Physiol Rev 85 1 201 279 (Pubitemid 40173995)
    • (2005) Physiological Reviews , vol.85 , Issue.1 , pp. 201-279
    • Verkhratsky, A.1
  • 18
    • 0033562966 scopus 로고    scopus 로고
    • Stress signaling from the lumen of the endoplasmic reticulum: Coordination of gene transcriptional and translational controls
    • R.J. Kaufman 1999 Stress signaling from the lumen of the endoplasmic reticulum: coordination of gene transcriptional and translational controls Genes Dev 13 10 1211 1233 (Pubitemid 29250189)
    • (1999) Genes and Development , vol.13 , Issue.10 , pp. 1211-1233
    • Kaufman, R.J.1
  • 19
    • 28144448251 scopus 로고    scopus 로고
    • Cellular abnormalities linked to endoplasmic reticulum dysfunction in cerebrovascular disease-therapeutic potential
    • DOI 10.1016/j.pharmthera.2005.05.008, PII S016372580500118X
    • W. Paschen T. Mengesdorf 2005 Cellular abnormalities linked to endoplasmic reticulum dysfunction in cerebrovascular disease-therapeutic potential Pharmacol Ther 108 3 362 375 (Pubitemid 41693766)
    • (2005) Pharmacology and Therapeutics , vol.108 , Issue.3 , pp. 362-375
    • Paschen, W.1    Mengesdorf, T.2
  • 20
    • 0033590451 scopus 로고    scopus 로고
    • Protein translation and folding are coupled by an endoplasmic- reticulum-resident kinase
    • DOI 10.1038/16729
    • H.P. Harding Y. Zhang D. Ron 1999 Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase Nature 397 6716 271 274 (Pubitemid 29051178)
    • (1999) Nature , vol.397 , Issue.6716 , pp. 271-274
    • Harding, H.P.1    Zhang, Y.2    Ron, D.3
  • 22
    • 0035966269 scopus 로고    scopus 로고
    • XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor
    • DOI 10.1016/S0092-8674(01)00611-0
    • H. Yoshida T. Matsui A. Yamamoto T. Okada K. Mori 2001 XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor Cell 107 7 881 891 (Pubitemid 34084979)
    • (2001) Cell , vol.107 , Issue.7 , pp. 881-891
    • Yoshida, H.1    Matsui, T.2    Yamamoto, A.3    Okada, T.4    Mori, K.5
  • 23
    • 0037011917 scopus 로고    scopus 로고
    • IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA
    • DOI 10.1038/415092a
    • M. Calfon H. Zeng F. Urano J.H. Till S.R. Hubbard H.P. Harding 2002 IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA Nature 415 6867 92 96 (Pubitemid 34062456)
    • (2002) Nature , vol.415 , Issue.6867 , pp. 92-96
    • Calfon, M.1    Zeng, H.2    Urano, F.3    Till, J.H.4    Hubbard, S.R.5    Harding, H.P.6    Clark, S.G.7    Ron, D.8
  • 24
    • 0033634654 scopus 로고    scopus 로고
    • Regulated translation initiation controls stress-induced gene expression in mammalian cells
    • H.P. Harding I. Novoa Y. Zhang H. Zeng R. Wek M. Schapira 2000 Regulated translation initiation controls stress-induced gene expression in mammalian cells Mol Cell 6 5 1099 1108
    • (2000) Mol Cell , vol.6 , Issue.5 , pp. 1099-1108
    • Harding, H.P.1    Novoa, I.2    Zhang, Y.3    Zeng, H.4    Wek, R.5    Schapira, M.6
  • 26
    • 0035947778 scopus 로고    scopus 로고
    • Feedback inhibition of the unfolded protein response by GADD34-mediated dephosphorylation of eIF2alpha
    • I. Novoa H. Zeng H.P. Harding D. Ron 2001 Feedback inhibition of the unfolded protein response by GADD34-mediated dephosphorylation of eIF2alpha J Cell Biol 153 5 1011 1022
    • (2001) J Cell Biol , vol.153 , Issue.5 , pp. 1011-1022
    • Novoa, I.1    Zeng, H.2    Harding, H.P.3    Ron, D.4
  • 27
    • 0141621215 scopus 로고    scopus 로고
    • Induction of Grp78/BiP by translational block: Activation of the Grp78 promoter by ATF4 through an upstream ATF/CRE site independent of the endoplasmic reticulum stress elements
    • DOI 10.1074/jbc.M303619200
    • S. Luo P. Baumeister S. Yang S.F. Abcouwer A.S. Lee 2003 Induction of Grp78/BiP by translational block: activation of the Grp78 promoter by ATF4 through and upstream ATF/CRE site independent of the endoplasmic reticulum stress elements J Biol Chem 278 39 37375 37385 (Pubitemid 37175256)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.39 , pp. 37375-37385
    • Luo, S.1    Baumeister, P.2    Yang, S.3    Abcouwer, S.F.4    Lee, A.S.5
  • 28
    • 1242272070 scopus 로고    scopus 로고
    • Induction of CHOP Expression by Amino Acid Limitation Requires Both ATF4 Expression and ATF2 Phosphorylation
    • DOI 10.1074/jbc.M311862200
    • J. Averous A. Bruhat C. Jousse V. Carraro G. Thiel P. Fafournoux 2004 Induction of CHOP expression by amino acid limitation requires both ATF4 expression and ATF2 phosphorylation J Biol Chem 279 7 5288 5297 (Pubitemid 38220549)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.7 , pp. 5288-5297
    • Averous, J.1    Bruhat, A.2    Jousse, C.3    Carraro, V.4    Thiel, G.5    Fafournoux, P.6
  • 29
    • 1842791361 scopus 로고    scopus 로고
    • Herp Is Dually Regulated by Both the Endoplasmic Reticulum Stress-specific Branch of the Unfolded Protein Response and A Branch That Is Shared with Other Cellular Stress Pathways
    • DOI 10.1074/jbc.M313724200
    • Y. Ma L.M. Hendershot 2004 Herp is dually regulated by both the endoplasmic reticulum stress-specific branch of the unfolded protein response and a branch that is shared with other cellular stress pathways J Biol Chem 279 14 13792 13799 (Pubitemid 38468910)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.14 , pp. 13792-13799
    • Ma, Y.1    Hendershot, L.M.2
  • 30
    • 1842843855 scopus 로고    scopus 로고
    • Roles of CHOP/GADD153 in endoplasmic reticulum stress
    • DOI 10.1038/sj.cdd.4401373
    • S. Oyadomari M. Mori 2004 Roles of CHOP/GADD153 in endoplasmic reticulum stress Cell Death Differ 11 4 381 389 (Pubitemid 38489416)
    • (2004) Cell Death and Differentiation , vol.11 , Issue.4 , pp. 381-389
    • Oyadomari, S.1    Mori, M.2
  • 31
    • 0034610743 scopus 로고    scopus 로고
    • Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-β
    • DOI 10.1038/47513
    • T. Nakagawa H. Zhu N. Morishima E. Li J. Xu B.A. Yankner 2000 Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta Nature 403 6765 98 103 (Pubitemid 30038529)
    • (2000) Nature , vol.403 , Issue.6765 , pp. 98-103
    • Nakagawa, T.1    Zhu, H.2    Morishima, N.3    Li, E.4    Xu, J.5    Yankner, B.A.6    Yuan, J.7
  • 32
    • 0034604033 scopus 로고    scopus 로고
    • Apoptotic crosstalk between the endoplasmic reticulum and mitochondria controlled by Bcl-2
    • J. Häcki L. Egger L. Monney S. Conus T. Rossé I. Fellay 2000 Apoptotic crosstalk between the endoplasmic reticulum and mitochondria controlled by Bcl-2 Oncogene 19 19 2286 2295 (Pubitemid 30307204)
    • (2000) Oncogene , vol.19 , Issue.19 , pp. 2286-2295
    • Hacki, J.1    Egger, L.2    Monney, L.3    Conus, S.4    Rosse, T.5    Fellay, I.6    Borner, C.7
  • 33
    • 0036312001 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress-induced cell death requires mitochondrial membrane permeabilization
    • DOI 10.1038/sj.cdd.4401006
    • P. Boya I. Cohen N. Zamzami H.L. Vieira G. Kroemer 2002 Endoplasmic reticulum stress-induced cell death requires mitochondrial membrane permeabilization Cell Death Differ 9 4 465 467 (Pubitemid 34814627)
    • (2002) Cell Death and Differentiation , vol.9 , Issue.4 , pp. 465-467
    • Boya, P.1    Cohen, I.2    Zamzami, N.3    Vieira, H.L.A.4    Kroemer, G.5
  • 34
    • 0037124113 scopus 로고    scopus 로고
    • BH-3-only BIK functions at the endoplasmic reticulum to stimulate cytochrome c release from mitochondria
    • DOI 10.1074/jbc.M201235200
    • M. Germain J.P. Mathai G.C. Shore 2002 BH-3-only BIK functions at the endoplasmic reticulum to stimulate cytochrome c release from mitochondria J Biol Chem 277 20 18053 18060 (Pubitemid 34967618)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.20 , pp. 18053-18060
    • Germain, M.1    Mathai, J.P.2    Shore, G.C.3
  • 36
    • 0032845121 scopus 로고    scopus 로고
    • Ischemic cell death in brain neurons
    • P. Lipton 1999 Ischemic cell death in brain neurons Physiol Rev 79 4 1431 1568 (Pubitemid 29473320)
    • (1999) Physiological Reviews , vol.79 , Issue.4 , pp. 1431-1568
    • Lipton, P.1
  • 37
    • 0029741890 scopus 로고    scopus 로고
    • Active cell death induced by the anti-estrogens tamoxifen and ICI 164 384 in human mammary carcinoma cells (MCF-7) in culture: The role of autophagy
    • W. Bursch A. Ellinger H. Kienzl L. Török S. Pandey M. Sikorska 1996 Active cell death induced by the anti-estrogens tamoxifen and ICI 164 384 in human mammary carcinoma cells (MCF-7) in culture: the role of autophagy Carcinogenesis 17 8 1595 1607 (Pubitemid 26280381)
    • (1996) Carcinogenesis , vol.17 , Issue.8 , pp. 1595-1607
    • Bursch, W.1    Ellinger, A.2    Kienzl, H.3    Torok, L.4    Pandey, S.5    Sikorska, M.6    Walker, R.7    Hermann, R.S.8
  • 38
    • 0027182917 scopus 로고
    • Protein kinases modulate the sensitivity of hippocampal neurons to nitric oxide toxicity and anoxia
    • K. Maiese I.R. Boniece K. Skurat J.A. Wagner 1993 Protein kinases modulate the sensitivity of hippocampal neurons to nitric oxide toxicity and anoxia J Neurosci Res 36 1 77 87 (Pubitemid 23260464)
    • (1993) Journal of Neuroscience Research , vol.36 , Issue.1 , pp. 77-87
    • Maiese, K.1    Boniece, I.R.2    Skurat, K.3    Wagner, J.A.4
  • 39
    • 33846565429 scopus 로고    scopus 로고
    • Ca2+ signals and neuronal death in brain ischemia
    • DOI 10.1161/01.STR.0000256294.46009.29, PII 0000767020070200100015
    • 2+ signals and neuronal death in brain ischemia Stroke 38 2Suppl 674 676 (Pubitemid 46184239)
    • (2007) Stroke , vol.38 , Issue.2 PART 2 , pp. 674-676
    • Bano, D.1    Nicotera, P.2
  • 40
    • 44349165060 scopus 로고    scopus 로고
    • Mechanisms of lysosomal proteases participating in cerebral ischemia-induced neuronal death
    • A.P. Qin H.L. Zhang Z.H. Qin 2008 Mechanisms of lysosomal proteases participating in cerebral ischemia-induced neuronal death Neurosci Bull 24 2 117 123
    • (2008) Neurosci Bull , vol.24 , Issue.2 , pp. 117-123
    • Qin, A.P.1    Zhang, H.L.2    Qin, Z.H.3
  • 42
    • 0042574218 scopus 로고    scopus 로고
    • Therapeutic induction of arteriogenesis in hypoperfused rat brain via granulocyte-macrophage colony-stimulating factor
    • DOI 10.1161/01.CIR.0000074209.17561.99
    • I.R. Buschmann H.J. Busch G. Mies K.A. Hossmann 2003 Therapeutic induction of arteriogenesis in hypoperfused rat brain via granulocyte-macrophage colony-stimulating factor Circulation 108 5 610 615 (Pubitemid 36961178)
    • (2003) Circulation , vol.108 , Issue.5 , pp. 610-615
    • Buschmann, I.R.1    Busch, H.-J.2    Mies, G.3    Hossmann, K.-A.4
  • 43
    • 32944479455 scopus 로고    scopus 로고
    • Therapeutically induced arteriogenesis in the brain. A new approach for the prevention of cerebral ischemia with vascular stenosis
    • H.J. Busch I. Buschmann E. Schneeloch C. Bode G. Mies K.A. Hossmann 2006 Therapeutically induced arteriogenesis in the brain. A new approach for the prevention of cerebral ischemia with vascular stenosis Nervenarzt 77 2 215 220
    • (2006) Nervenarzt , vol.77 , Issue.2 , pp. 215-220
    • Busch, H.J.1    Buschmann, I.2    Schneeloch, E.3    Bode, C.4    Mies, G.5    Hossmann, K.A.6
  • 44
    • 0030666876 scopus 로고    scopus 로고
    • Cerestat and other NMDA antagonists in ischemic stroke
    • K.R. Lees 1997 Cerestat and other NMDA antagonists in ischemic stroke Neurology 49 5Suppl4 S66 69
    • (1997) Neurology , vol.49 , Issue.5 SUPPL4 , pp. 66-69
    • Lees, K.R.1
  • 45
    • 0028897733 scopus 로고
    • Clinical experience with excitatory amino acid antagonist drugs
    • K.W. Muir K.R. Lees 1995 Clinical experience with excitatory amino acid antagonist drugs Stroke 26 3 503 513
    • (1995) Stroke , vol.26 , Issue.3 , pp. 503-513
    • Muir, K.W.1    Lees, K.R.2
  • 47
    • 16644384790 scopus 로고    scopus 로고
    • Role of magnesium ions on the regulation of NMDA receptor-a pharmacopathology of memantine
    • T. Kato 2004 Role of magnesium ions on the regulation of NMDA receptor-a pharmacopathology of memantine Clin Calcium 14 8 76 80
    • (2004) Clin Calcium , vol.14 , Issue.8 , pp. 76-80
    • Kato, T.1
  • 48
    • 0033429415 scopus 로고    scopus 로고
    • Novel targets for therapeutic intervention against ischemic brain injury
    • A. Sun J. Cheng 1999 Novel targets for therapeutic intervention against ischemic brain injury Clin Neuropharmacol 22 3 164 171 (Pubitemid 30002782)
    • (1999) Clinical Neuropharmacology , vol.22 , Issue.3 , pp. 164-171
    • Sun, A.1    Cheng, J.2
  • 49
    • 0028500548 scopus 로고
    • The pharmacology of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA)/kainate antagonists and their role in cerebral ischaemia
    • R. Gill 1994 The pharmacology of alpha-amino-3-hydroxy-5-methyl-4- isoxazole propionate (AMPA)/kainate antagonists and their role in cerebral ischaemia Cerebrovasc Brain Metab Rev 6 3 225 256 (Pubitemid 2131357)
    • (1994) CEREBROVASC.BRAIN METAB.REV. , vol.6 , Issue.3 , pp. 225-256
    • Gill, R.1
  • 51
    • 49849105694 scopus 로고    scopus 로고
    • Dopamine D1-like receptors depress excitatory synaptic transmissions in striatal neurons after transient forebrain ischemia
    • Y. Zhang P. Deng Y. Ruan Z.C. Xu 2008 Dopamine D1-like receptors depress excitatory synaptic transmissions in striatal neurons after transient forebrain ischemia Stroke 39 8 2370 2376
    • (2008) Stroke , vol.39 , Issue.8 , pp. 2370-2376
    • Zhang, Y.1    Deng, P.2    Ruan, Y.3    Xu, Z.C.4
  • 53
    • 0030768341 scopus 로고    scopus 로고
    • Neuroprotective effects of dexmedetomidine in the gerbil hippocampus after transient global ischemia
    • DOI 10.1097/00000542-199708000-00025
    • J. Kuhmonen J. Pokorný R. Miettinen A. Haapalinna J. Jolkkonen P. Riekkinen Sr 1997 Neuroprotective effects of dexmedetomidine in the gerbil hippocampus after transient global ischemia Anesthesiology 87 2 371 377 (Pubitemid 27435380)
    • (1997) Anesthesiology , vol.87 , Issue.2 , pp. 371-377
    • Kuhmonen, J.1    Pokorny, J.2    Miettinen, R.3    Haapalinna, A.4    Jolkkonen, J.5    Riekkinen Sr., P.6    Sivenius, J.7
  • 54
    • 3042687473 scopus 로고    scopus 로고
    • 5-HT control of ischemia-evoked glutamate efflux from human cerebrocortical slices
    • DOI 10.1016/j.neuint.2004.03.004, PII S0197018604000518
    • M. Marcoli C. Cervetto M. Castagnetta P. Sbaffi G. Maura 2004 5-HT control of ischemia-evoked glutamate efflux from human cerebrocortical slices Neurochem Int 45 5 687 691 (Pubitemid 38844890)
    • (2004) Neurochemistry International , vol.45 , Issue.5 , pp. 687-691
    • Marcoli, M.1    Cervetto, C.2    Castagnetta, M.3    Sbaffi, P.4    Maura, G.5
  • 55
    • 57049115942 scopus 로고    scopus 로고
    • Neuroprotection of gamma-aminobutyric acid receptor agonists via enhancing neuronal nitric oxide synthase (Ser847) phosphorylation through increased neuronal nitric oxide synthase and PSD95 interaction and inhibited protein phosphatase activity in cerebral ischemia
    • C. Zhou C. Li H.M. Yu F. Zhang D. Han G.Y. Zhang 2008 Neuroprotection of gamma-aminobutyric acid receptor agonists via enhancing neuronal nitric oxide synthase (Ser847) phosphorylation through increased neuronal nitric oxide synthase and PSD95 interaction and inhibited protein phosphatase activity in cerebral ischemia J Neurosci Res 86 13 2973 2983
    • (2008) J Neurosci Res , vol.86 , Issue.13 , pp. 2973-2983
    • Zhou, C.1    Li, C.2    Yu, H.M.3    Zhang, F.4    Han, D.5    Zhang, G.Y.6
  • 56
    • 33947111868 scopus 로고    scopus 로고
    • The effects of Shuxuetong on the pathology of cerebral ischemia-reperfusion injury and GABA and TNF-alpha expression in gerbil models
    • D.J. Zhang G.R. Xu Z.Y. Li Y.Z. Li L.X. Xu F.Y. Lu 2006 The effects of Shuxuetong on the pathology of cerebral ischemia-reperfusion injury and GABA and TNF-alpha expression in gerbil models Neurosci Bull 22 1 41 46
    • (2006) Neurosci Bull , vol.22 , Issue.1 , pp. 41-46
    • Zhang, D.J.1    Xu, G.R.2    Li, Z.Y.3    Li, Y.Z.4    Xu, L.X.5    Lu, F.Y.6
  • 58
    • 4544386279 scopus 로고    scopus 로고
    • Neuroprotection against ischemic/hypoxic brain damage: Blockers of ionotropic glutamate receptor and voltage sensitive calcium channels
    • DOI 10.2174/1389450043345209
    • A. Schurr 2004 Neuroprotection against ischemic/hypoxic brain damage: blockers of ionotropic glutamate receptor and voltage sensitive calcium channels Curr Drug Targets 5 7 603 618 (Pubitemid 39242869)
    • (2004) Current Drug Targets , vol.5 , Issue.7 , pp. 603-618
    • Schurr, A.1
  • 59
    • 0030580427 scopus 로고    scopus 로고
    • Time-course and treatment response with SNX-111, an N-type calcium channel blocker, in a rodent model of focal cerebral ischemia using diffusion-weighted MRI
    • DOI 10.1016/S0006-8993(96)00808-6, PII S0006899396008086
    • M.A. Yenari J.T. Palmer G.H. Sun A. de Crespigny M.E. Mosely G.K. Steinberg 1996 Time-course and treatment response with SNX-111, an N-type calcium channel blocker, in a rodent model of focal cerebral ischemia using diffusion-weighted MRI Brain Res 739 1-2 36 45 (Pubitemid 26387360)
    • (1996) Brain Research , vol.739 , Issue.1-2 , pp. 36-45
    • Yenari, M.A.1    Palmer, J.T.2    Sun, G.H.3    De Crespigny, A.4    Moseley, M.E.5    Steinberg, G.K.6
  • 60
    • 0031266451 scopus 로고    scopus 로고
    • Effects of Isradipine, an L-Type Calcium Channel Blocker on Permanent and Transient Focal Cerebral Ischemia in Spontaneously Hypertensive Rats
    • C.A. Campbell K.B. Mackay S. Patel P.D. King J.L. Stretton S.J. Hadingham 1997 Effects of isradipine, an L-type calcium channel blocker on permanent and transient focal cerebral ischemia in spontaneously hypertensive rats Exp Neurol 148 1 45 50 (Pubitemid 127445113)
    • (1997) Experimental Neurology , vol.148 , Issue.1 , pp. 45-50
    • Campbell, C.A.1    Mackay, K.B.2    Patel, S.3    King, P.D.4    Stretton, J.L.5    Hadingham, S.J.6    Hamilton, T.C.7
  • 62
    • 34547128100 scopus 로고    scopus 로고
    • Pinacidil reduces neuronal apoptosis following cerebral ischemia-reperfusion in rats through both mitochondrial and death-receptor signal pathways
    • H. Zhang L.C. Song Y.Y. Liu Y. Ma Y.L. Lu 2007 Pinacidil reduces neuronal apoptosis following cerebral ischemia-reperfusion in rats through both mitochondrial and death-receptor signal pathways Neurosci Bull 23 3 145 150
    • (2007) Neurosci Bull , vol.23 , Issue.3 , pp. 145-150
    • Zhang, H.1    Song, L.C.2    Liu, Y.Y.3    Ma, Y.4    Lu, Y.L.5
  • 63
    • 33947356269 scopus 로고    scopus 로고
    • Neuroprotective effect of MnTMPyP, a superoxide dismutase/catalase mimetic in global cerebral ischemia is mediated through reduction of oxidative stress and DNA fragmentation
    • DOI 10.1016/j.ejphar.2006.12.039, PII S0014299907000581
    • S.S. Sharma S. Gupta 2007 Neuroprotective effect of MnTMPyP, a superoxide dismutase/catalase mimetic in global cerebral ischemia is mediated through reduction of oxidative stress and DNA fragmentation Eur J Pharmacol 561 1-3 72 79 (Pubitemid 46454227)
    • (2007) European Journal of Pharmacology , vol.561 , Issue.1-3 , pp. 72-79
    • Sharma, S.S.1    Gupta, S.2
  • 64
    • 0028271830 scopus 로고
    • Dose-response analysis of the effect of 21-aminosteroid tirilazad mesylate (U-74006F) upon neurological outcome and ischemic brain damage in permanent focal cerebral ischemia
    • C.K. Park E.D. Hall 1994 Dose-response analysis of the effect of 21-aminosteroid tirilazad mesylate (U-74006F) upon neurological outcome and ischemic brain damage in permanent focal cerebral ischemia Brain Res 645 1-2 157 163 (Pubitemid 24140122)
    • (1994) Brain Research , vol.645 , Issue.1-2 , pp. 157-163
    • Park, C.K.1    Hall, E.D.2
  • 65
    • 0030976073 scopus 로고    scopus 로고
    • Pharmacology of lazaroids and brain energy metabolism: A review
    • R.F. Villa A. Gorini 1997 Pharmacology of lazaroids and brain energy metabolism: a review Pharmacol Rev 49 1 99 136 (Pubitemid 27142418)
    • (1997) Pharmacological Reviews , vol.49 , Issue.1 , pp. 99-136
    • Villa, R.F.1    Gorini, A.2
  • 66
    • 33746549327 scopus 로고    scopus 로고
    • Neuroprotective effects of edaravone: A novel free radical scavenger in cerebrovascular injury
    • DOI 10.1111/j.1527-3458.2006.00009.x
    • H. Yoshida H. Yanai Y. Namiki K. Fukatsu-Sasaki N. Furutani N. Tada 2006 Neuroprotective effects of edaravone: a novel free radical scavenger in cerebrovascular injury CNS Drug Rev 12 1 9 20 (Pubitemid 44133577)
    • (2006) CNS Drug Reviews , vol.12 , Issue.1 , pp. 9-20
    • Yoshida, H.1    Yanai, H.2    Namiki, Y.3    Fukatsu-Sasaki, K.4    Furutani, N.5    Tada, N.6
  • 67
    • 0038810306 scopus 로고    scopus 로고
    • Brain edema induced by in vitro ischemia: Causal factors and neuroprotection
    • DOI 10.1046/j.1471-4159.2003.01772.x
    • D.G. [tmp] MacGregor M.V. Avshalumov M.E. Rice 2003 Brain edema induced by in vitro ischemia: causal factors and neuroprotection J Neurochem 85 6 1402 1411 (Pubitemid 36702553)
    • (2003) Journal of Neurochemistry , vol.85 , Issue.6 , pp. 1402-1411
    • MacGregor, D.G.1    Avshalumov, M.V.2    Rice, M.E.3
  • 68
    • 0036098259 scopus 로고    scopus 로고
    • Neuroprotective effects of the spin trap agent disodium-[(tert- butylimino)methyl]benzene-1,3-disulfonate N-oxide (generic NXY-059) in a rabbit small clot embolic stroke model: Combination studies with the thrombolytic tissue plasminogen activator
    • DOI 10.1161/01.STR.0000015346.00054.8B
    • P.A. Lapchak D.M. Araujo D. Song J. Wei J.A. Zivin 2002 Neuroprotective effects of the spin trap agent disodium-[(tert-butylimino)methyl] benzene-1,3-disulfonate N-oxide (generic NXY-059) in a rabbit small clot embolic stroke model: combination studies with the thrombolytic tissue plasminogen activator Stroke 33 5 1411 1415 (Pubitemid 34517068)
    • (2002) Stroke , vol.33 , Issue.5 , pp. 1411-1415
    • Lapchak, P.A.1    Araujo, D.M.2    Song, D.3    Wei, J.4    Zivin, J.A.5
  • 69
    • 0032826065 scopus 로고    scopus 로고
    • Neuroprotective properties of statins in cerebral ischemia and stroke
    • C.J. Vaughan N. Delanty 1999 Neuroprotective properties of statins in cerebral ischemia and stroke Stroke 30 9 1969 1973 (Pubitemid 29411843)
    • (1999) Stroke , vol.30 , Issue.9 , pp. 1969-1973
    • Vaughan, C.J.1    Delanty, N.2
  • 70
    • 53949090120 scopus 로고    scopus 로고
    • Minocycline attenuates cognitive impairment and restrains oxidative stress in the hippocampus of rats with chronic cerebral hypoperfusion
    • Z.Y. Cai Y. Yan S.Q. Sun J. Zhang L.G. Huang N. Yan 2008 Minocycline attenuates cognitive impairment and restrains oxidative stress in the hippocampus of rats with chronic cerebral hypoperfusion Neurosci Bull 24 5 305 313
    • (2008) Neurosci Bull , vol.24 , Issue.5 , pp. 305-313
    • Cai, Z.Y.1    Yan, Y.2    Sun, S.Q.3    Zhang, J.4    Huang, L.G.5    Yan, N.6
  • 72
    • 0037756715 scopus 로고    scopus 로고
    • Neuroprotection of naloxone against ischemic injury in rats: Role of mu receptor antagonism
    • S.L. Liao W.Y. Chen S.L. Raung C.J. Chen 2003 Neuroprotection of naloxone against ischemic injury in rats: role of mu receptor antagonism Neurosci Lett 345 3 169 172
    • (2003) Neurosci Lett , vol.345 , Issue.3 , pp. 169-172
    • Liao, S.L.1    Chen, W.Y.2    Raung, S.L.3    Chen, C.J.4
  • 73
    • 0032192489 scopus 로고    scopus 로고
    • Hu23F2G, an antibody recognizing the leukocyte CD 11/CD 18 integrin, reduces injury in a rabbit model of transient focal cerebral ischemia
    • DOI 10.1006/exnr.1998.6876
    • M.A. Yenari D. Kunis G.H. Sun D. Onley L. Watson S. Turner 1998 Hu23F2G, an antibody recognizing the leukocyte CD11/CD18 integrin, reduces injury in a rabbit model of transient focal cerebral ischemia Exp Neurol 153 2 223 233 (Pubitemid 28489889)
    • (1998) Experimental Neurology , vol.153 , Issue.2 , pp. 223-233
    • Yenari, M.A.1    Kunis, D.2    Sun, G.H.3    Onley, D.4    Watson, L.5    Turner, S.6    Whitaker, S.7    Steinberg, G.K.8
  • 74
    • 54049115560 scopus 로고    scopus 로고
    • Activation of liver X receptors promotes neuroprotection and reduces brain inflammation in experimental stroke
    • J.R. Morales I. Ballesteros J.M. Deniz O. Hurtado J. Vivancos F. Nombela 2008 Activation of liver X receptors promotes neuroprotection and reduces brain inflammation in experimental stroke Circulation 118 14 1450 1459
    • (2008) Circulation , vol.118 , Issue.14 , pp. 1450-1459
    • Morales, J.R.1    Ballesteros, I.2    Deniz, J.M.3    Hurtado, O.4    Vivancos, J.5    Nombela, F.6
  • 75
    • 33750085875 scopus 로고    scopus 로고
    • Neuroprotectant FK506 inhibits glutamate-induced apoptosis of astrocytes in vitro and in vivo
    • DOI 10.1111/j.1471-4159.2006.04136.x
    • K. Szydlowska M. Zawadzka B. Kaminska 2006 Neuroprotectant FK506 inhibits glutamate-induced apoptosis of astrocytes in vitro and in vivo J Neurochem 99 3 965 975 (Pubitemid 44583453)
    • (2006) Journal of Neurochemistry , vol.99 , Issue.3 , pp. 965-975
    • Szydlowska, K.1    Zawadzka, M.2    Kaminska, B.3
  • 77
    • 85052610420 scopus 로고    scopus 로고
    • A novel neuroprotective compound FR901459 with dual inhibition of calcineurin and cyclophilins
    • H. Uchino S. Morota T. Takahashi Y. Ikeda Y. Kudo N. Ishii 2006 A novel neuroprotective compound FR901459 with dual inhibition of calcineurin and cyclophilins Acta Neurochir Suppl 96 157 162
    • (2006) Acta Neurochir Suppl , vol.96 , pp. 157-162
    • Uchino, H.1    Morota, S.2    Takahashi, T.3    Ikeda, Y.4    Kudo, Y.5    Ishii, N.6
  • 79
    • 15244351970 scopus 로고    scopus 로고
    • 2A receptor antagonism in cerebral ischemia
    • DOI 10.1179/016164105X21913
    • F. Pedata M. Gianfriddo D. Turchi A. Melani 2005 The protective effect of adenosine A2A receptor antagonism in cerebral ischemia Neurol Res 27 2 169 174 (Pubitemid 40388422)
    • (2005) Neurological Research , vol.27 , Issue.2 , pp. 169-174
    • Pedata, F.1    Gianfriddo, M.2    Turchi, D.3    Melani, A.4
  • 80
    • 0042305247 scopus 로고    scopus 로고
    • 2A adenosine receptors prevents basic fibroblast growth factor-induced reactive astrogliosis in rat striatal primary astrocytes
    • DOI 10.1002/glia.10243
    • R. Brambilla L. Cottini M. Fumagalli S. Ceruti M.P. Abbracchio 2003 Blockade of A2A adenosine receptors prevents basic fibroblast growth factor-induced reactive astrogliosis in rat striatal primary astrocytes Glia 43 2 190 194 (Pubitemid 36897280)
    • (2003) GLIA , vol.43 , Issue.2 , pp. 190-194
    • Brambilla, R.1    Cottini, L.2    Fumagalli, M.3    Ceruti, S.4    Abbracchio, M.P.5
  • 81
    • 0034255042 scopus 로고    scopus 로고
    • BDNF protects the neonatal brain from hypoxic-ischemic injury in vivo via the ERK pathway
    • B.H. Han D.M. Holtzman 2000 BDNF protects the neonatal brain from hypoxic-ischemic injury in vivo via the ERK pathway J Neurosci 20 15 5775 5781 (Pubitemid 30636906)
    • (2000) Journal of Neuroscience , vol.20 , Issue.15 , pp. 5775-5781
    • Han, B.H.1    Holtzman, D.M.2
  • 83
    • 33746191796 scopus 로고    scopus 로고
    • Neuroprotection by ovarian hormones in animal models of neurological disease
    • DOI 10.1385/ENDO:29:2:217, PII ENDO292217
    • G.E. Hoffman I. Merchenthaler S.L. Zup 2006 Neuroprotection by ovarian hormones in animal models of neurological disease Endocrine 29 2 217 231 (Pubitemid 44097365)
    • (2006) Endocrine , vol.29 , Issue.2 , pp. 217-231
    • Hoffman, G.E.1    Merchenthaler, I.2    Zup, S.L.3
  • 84
    • 44049100503 scopus 로고    scopus 로고
    • The experimental and clinical pharmacology of propofol, an anesthetic agent with neuroprotective properties
    • DOI 10.1111/j.1527-3458.2008.00043.x
    • Y. Kotani M. Shimazawa S. Yoshimura T. Iwama H. Hara 2008 The experimental and clinical pharmacology of propofol, an anesthetic agent with neuroprotective properties CNS Neurosci Ther 14 2 95 106 (Pubitemid 351713319)
    • (2008) CNS Neuroscience and Therapeutics , vol.14 , Issue.2 , pp. 95-106
    • Kotani, Y.1    Shimazawa, M.2    Yoshimura, S.3    Iwama, T.4    Hara, H.5
  • 85
    • 56149093066 scopus 로고    scopus 로고
    • Xenon and sevoflurane protect against brain injury in a neonatal asphyxia model
    • Y. Luo D. Ma E. Ieong R.D. Sanders B. Yu M. Hossain 2008 Xenon and sevoflurane protect against brain injury in a neonatal asphyxia model Anesthesiology 109 5 782 789
    • (2008) Anesthesiology , vol.109 , Issue.5 , pp. 782-789
    • Luo, Y.1    Ma, D.2    Ieong, E.3    Sanders, R.D.4    Yu, B.5    Hossain, M.6
  • 86
    • 0032876536 scopus 로고    scopus 로고
    • Combination drug therapy and mild hypothermia: A promising treatment strategy for reversible, focal cerebral ischemia
    • R. Schmid-Elsaesser E. Hungerhuber S. Zausinger A. Baethmann H.J. Reulen 1999 Combination drug therapy and mild hypothermia: a promising treatment strategy for reversible, focal cerebral ischemia Stroke 30 9 1891 1899 (Pubitemid 29411833)
    • (1999) Stroke , vol.30 , Issue.9 , pp. 1891-1899
    • Schmid-Elsaesser, R.1    Hungerhuber, E.2    Zausinger, S.3    Baethmann, A.4    Reulen, H.-J.5
  • 87
    • 33847057983 scopus 로고    scopus 로고
    • Protective Effect of Ginkgo Biloba Extract on Brain Injury Induced by Ischemia/Reperfusion in Rats
    • X.S. Wang X.Z. Ruan W. Wang 2003 Protective Effect of Ginkgo Biloba Extract on Brain Injury Induced by Ischemia/Reperfusion in Rats J Huazhong Univ Sci Tech[Health Sci] 32 5 500 502
    • (2003) J Huazhong Univ Sci Tech[Health Sci] , vol.32 , Issue.5 , pp. 500-502
    • Wang, X.S.1    Ruan, X.Z.2    Wang, W.3
  • 88
    • 67650731185 scopus 로고    scopus 로고
    • Protective effects of PTS on cerebral ischemia-reperfusion injury in rat
    • X.S. Hu D. Zhou D.M. Zhou 2004 Protective effects of PTS on cerebral ischemia-reperfusion injury in rat J Apoplexy and Nervous Disease 21 4 354 356
    • (2004) J Apoplexy and Nervous Disease , vol.21 , Issue.4 , pp. 354-356
    • Hu, X.S.1    Zhou, D.2    Zhou, D.M.3
  • 89
    • 67650724421 scopus 로고    scopus 로고
    • The mechanism of protective effects of puerarin on learning-memory disorder after global cerebral ischemic reperfusive injury in rats
    • H.Q. Wu M.Z. Chang G.L. Zhang Y.X. Zhao 2004 The mechanism of protective effects of puerarin on learning-memory disorder after global cerebral ischemic reperfusive injury in rats J Apoplexy and Nervous Disease 21 4 350 353
    • (2004) J Apoplexy and Nervous Disease , vol.21 , Issue.4 , pp. 350-353
    • Wu, H.Q.1    Chang, M.Z.2    Zhang, G.L.3    Zhao, Y.X.4
  • 92
    • 0038060334 scopus 로고    scopus 로고
    • Ischemic tolerance and endogenous neuroprotection
    • DOI 10.1016/S0166-2236(03)00071-7
    • U. Dirnagl R.P. Simon J.M. Hallenbeck 2003 Ischemic tolerance and endogenous neuroprotection Trends Neurosci 26 5 248 254 (Pubitemid 36556155)
    • (2003) Trends in Neurosciences , vol.26 , Issue.5 , pp. 248-254
    • Dirnagl, U.1    Simon, R.P.2    Hallenbeck, J.M.3
  • 93
    • 53949095181 scopus 로고    scopus 로고
    • Ischemic preconditioning induces chaperone hsp70 expression and inhibits protein aggregation in the CA1 neurons of rats
    • P.F. Ge T.F. Luo J.Z. Zhang D.W. Chen Y.X. Luan S.L. Fu 2008 Ischemic preconditioning induces chaperone hsp70 expression and inhibits protein aggregation in the CA1 neurons of rats Neurosci Bull 24 5 288 296
    • (2008) Neurosci Bull , vol.24 , Issue.5 , pp. 288-296
    • Ge, P.F.1    Luo, T.F.2    Zhang, J.Z.3    Chen, D.W.4    Luan, Y.X.5    Fu, S.L.6
  • 94
    • 38349124184 scopus 로고    scopus 로고
    • Molecular physiology of preconditioning-induced brain tolerance to ischemia
    • T.P. Obrenovitch 2008 Molecular physiology of preconditioning-induced brain tolerance to ischemia Physiol Rev 88 1 211 247
    • (2008) Physiol Rev , vol.88 , Issue.1 , pp. 211-247
    • Obrenovitch, T.P.1
  • 95
    • 49849103054 scopus 로고    scopus 로고
    • Ischemic postconditioning inhibits apoptosis after focal cerebral ischemia/reperfusion injury in the rat
    • B. Xing H. Chen M. Zhang D. Zhao R. Jiang X. Liu 2008 Ischemic postconditioning inhibits apoptosis after focal cerebral ischemia/reperfusion injury in the rat Stroke 39 8 2362 2369
    • (2008) Stroke , vol.39 , Issue.8 , pp. 2362-2369
    • Xing, B.1    Chen, H.2    Zhang, M.3    Zhao, D.4    Jiang, R.5    Liu, X.6
  • 96
    • 41249084455 scopus 로고    scopus 로고
    • Ischemic postconditioning protects against global cerebral ischemia/reperfusion-induced injury in rats
    • DOI 10.1161/STROKEAHA.107.499079
    • J.Y. Wang J. Shen Q. Gao Z.G. Ye S.Y. Yang H.W. Liang 2008 Ischemic postconditioning protects against global cerebral ischemia/reperfusion-induced injury in rats Stroke 39 3 983 990 (Pubitemid 351619573)
    • (2008) Stroke , vol.39 , Issue.3 , pp. 983-990
    • Wang, J.-Y.1    Shen, J.2    Gao, Q.3    Ye, Z.-G.4    Yang, S.-Y.5    Liang, H.-W.6    Bruce, I.C.7    Luo, B.-Y.8    Xia, Q.9
  • 97
    • 34250305937 scopus 로고    scopus 로고
    • Neuroprotection: Challenges and opportunities
    • DOI 10.1001/archneur.64.6.794
    • A.I. Faden B. Stoica 2007 Neuroprotection: challenges and opportunities Arch Neurol 64 6 794 800 (Pubitemid 46919833)
    • (2007) Archives of Neurology , vol.64 , Issue.6 , pp. 794-800
    • Faden, A.I.1    Stoica, B.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.