Mechanisms of lysosomal proteases participating in cerebral ischemia-induced neuronal death

Neuroscience Bulletin

Volumn 24, Issue 2, 2008, Pages 117-123

  Qin, Ai Ping ^a   Zhang, Hui Ling ^a   Qin, Zheng Hong ^a  

^a MEDICAL COLLEGE OF SOOCHOW UNIVERSITY   (China)

Author keywords

Apoptosis; Autophagy; Cathepsin; Cerebral ischemia; Lysosomes; Necrosis

Indexed keywords

4 AMINOBUTYRIC ACID RECEPTOR STIMULATING AGENT; ALOXISTATIN ACID; CALCIUM CHANNEL BLOCKING AGENT; CATHEPSIN B INHIBITOR; GLUTAMATE RECEPTOR ANTAGONIST; N (3 PROPYLCARBAMOYLOXIRANE 2 CARBONYL)ISOLEUCYLPROLINE; POTASSIUM CHANNEL BLOCKING AGENT; PROTEINASE; SODIUM CHANNEL BLOCKING AGENT; STEFIN A;

APOPTOSIS; AUTOPHAGY; BRAIN DAMAGE; BRAIN ISCHEMIA; CELL DEATH; CYTOPLASM; LYSOSOME; NECROSIS; NERVE CELL NECROSIS; NEUROPROTECTION; NONHUMAN; SHORT SURVEY; STROKE;

ANIMALS; APOPTOSIS; AUTOPHAGY; BRAIN INFARCTION; BRAIN ISCHEMIA; CATHEPSINS; HUMANS; LYSOSOMES; NECROSIS; NERVE DEGENERATION; PEPTIDE HYDROLASES;

EID: 44349165060     PISSN: 16737067     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12264-008-0117-3     Document Type: Short Survey

References (45)

1. Schweichel JU, Merker HJ. The morphology of various types of cell death in prenatal tissues. Teratology 1973, 7: 253-266.
2. de Duve C. Lysosomes revisited. Eur J Biochem 1983, 137: 391-397.
3. Tardy C, Codogno P, Autefage H, Levade T, Andrieu-Abadie N. Lysosomes and lysosomal proteins in cancer cell death (new players of an old struggle). Biochim Biophys Acta 2006, 1765:101-125.
4. Yamashima T. Implication of cysteine proteases calpain, cathepsin and caspase in ischemic neuronal death of primates. Prog Neurobiol 2000, 62: 273-295.
5. Nitatori T, Sato N, Waguri S, Karasawa Y, Araki H, Shibanai K, et al. Delayed neuronal death in the CA1 pyramidal cell layer of the gerbil hippocampus following transient ischemia is apoptosis. J Neurosci 1995, 15: 1001-1011.
6. Seyfried D, Han Y, Zheng Z, Day N, Moin K, Rempel S, et al. Cathepsin B and middle cerebral artery occlusion in the rat. J Neurosurg 1997, 87: 716-723.
7. Benchoua A, Braudeau J, Reis A, Couriaud C, Onténiente B. Activation of proinflammatory caspases by cathepsin B in focal cerebral ischemia. J Cereb Blood Flow Metab 2004, 24: 1272-1279.
8. Tsubokawa T, Solaroglu I, Yatsushige H, Cahill J, Yata K, Zhang JH. Cathepsin and calpain inhibitor E64d attenuates matrix metalloproteinase-9 activity after focal cerebral ischemia in rats. Stroke 2006, 37: 1888-1894.
9. Kagedal K, Zhao M, Svensson I, Brunk UT. Sphingosine-induced apoptosis is dependent on lysosomal proteases. Biochem J 2001, 359: 335-343.
10. Imagawa DK, Osifchin NE, Paznekas WA, Shin ML, Mayer MM. Consequences of cell membrane attack by complement: release of arachidonate and formation of inflammatory derivatives. Proc Natl Acad Sci USA 1983, 80: 6647-6651.
11. İlekel H, İlekel S, Güner G, Özdamar N. Evaluation of lipid peroxidation, cathepsin L and acid phosphatase activities in experimental brain ischemia-reperfusion. Brain Res 1999, 843:18-24.
12. 2+, PIP2 and calpain responses prior to delayed neuronal death in monkeys. Eur J Neurosci 1996, 8: 1932-1944.
13. Kagedal K, Johansson AC, Johansson U, Heimlich G, Roberg K, Wang NS, et al. Lysosomal membrane permeabilization during apoptosis-involvement of Bax? Int J Exp Pathol 2005, 86:309-321.
14. Zhao M, Eaton JW, Brunk UT. Protection against oxidant-mediated lysosomal rupture: a new anti-apoptotic activity of Bcl-2? FEBS Lett 2000, 485: 104-108.
15. Zhao M, Eaton JW, Brunk UT. Bcl-2 phosphorylation is required for inhibition of oxidative stress-induced lysosomal leak and ensuing apoptosis. FEBS Lett 2001, 509: 405-412.
16. Werneburg NW, Guicciardi ME, Bronk SF, Gores GJ. Tumor necrosis factor-alpha-associated lysosomal permeabilization is cathepsin B dependent. Am J Physiol Gastrointest Liver Physiol 2002, 283: G947-G956.
17. Liu N, Raja SM, Zazzeroni F, Metkar SS, Shah R, Zhang M, et al. NF-kappaB protects from the lysosomal pathway of cell death. EMBO J 2003, 22: 5313-5322.
18. Zeng YS, Xu ZC. Co-existence of necrosis and apoptosis in rat hippocampus following transient forebrain ischemia. Neurosci Res 2000, 37: 113-125.
19. Ünal-Çevik I, Kilinç M, Can A, Gürsoy- Özdemir Y, Dalkara T. Apoptotic and Necrotic Death Mechanisms Are Concomitantly Activated in the Same Cell After Cerebral Ischemia. Stroke 2004, 35: 2189-2194.
20. Wei L, Ying DJ, Cui L, Langsdorf J, Yu SP. Necrosis, apoptosis and hybrid death in the cortex and thalamus after barrel cortex ischemia in rats. Brain Res 2004, 1022: 54-61.
21. Li W, Yuan X, Nordgren G, Dalen H, Dubowchik GM, Firestone RA, et al. Induction of cell death by the lysosomotropic detergent MSDH. FEBS Lett 2000, 470: 35-39.
22. Brunk UT, Neuzil J, Eaton JW. Lysosomal involvement in apoptosis. Redox Rep 2001, 6: 91-97.
23. Cirman T, Oresiæ K, Mazovec GD, Turk V, Reed JC, Myers RM, et al. Selective disruption of lysosomes in HeLa cells triggers apoptosis mediated by cleavage of Bid by multiple papain-like lysosomal cathepsins. J Biol Chem 2004, 279: 3578-3587.
24. Guicciardi ME, Leist M, Gores GJ. Lysosomes in cell death. Oncogene 2004, 23: 2881-2890.
25. Bidère N, Lorenzo HK, Carmona S, Laforge M, Harper F, Dumont C, et al. Cathepsin D triggers Bax activation, resulting in selective apoptosis-inducing factor (AIF) relocation in T lymphocytes entering the early commitment phase to apoptosis. J Biol Chem 2003, 278: 31401-31411.
26. Heinrich M, Neumeyer J, Jakob M, Hallas C, Tchikov V, Winoto-Morbach S, et al. Cathepsin D links TNF-induced acid sphingomyelinase to Bid-mediated caspase-9 and-3 activation. Cell Death Differ 2004, 11: 550-563.
27. Li P, Nijhawan D, Budihardjo I, Srinivasula SM, Ahmad M, Alnemri ES, et al. Cytochrome c and dATP-dependent formation of Apaf-1/Caspase-9 complex initiates an apoptotic protease cascade. Cell 1997, 91: 479-489.
28. Zou H, Henzel WJ, Liu X, Lutschg A, Wang X. Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3. Cell 1997, 90: 405-413.
29. Wang Y, Gu ZL, Cao Y, Liang ZQ, Han R, Bennett MC, et al. Lysosomal enzyme cathepsin B is involved in kainic acid-induced excitotoxicity in rat striatum. Brain Res 2006, 1071: 245-249.
30. Klionsky DJ, Emr SD. Autophagy as a regulated pathway of cellular degradation. Science 2000, 290: 1717-1721.
31. Zhu C, Wang X, Xu F, Bahr BA, Shibata M, Uchiyama Y, et al. The influence of age on apoptotic and other mechanisms of cell death after cerebral hypoxia-ischemia. Cell Death Differ 2005, 12: 162-176.
32. Adhami F, Liao G, Morozov YM, Schloemer A, Schmithorst VJ, Lorenz JN, et al. Cerebral ischemia-hypoxia induces intravascular coagulation and autophagy. Am J Pathol 2006, 169: 566-583.
33. Ohsawa Y, Isahara K, Kanamori S, Shibata M, Kametaka S, Gotow T, et al. An ultrastructural and immunohistochemical study of PC12 cells during apoptosis induced by serum deprivation with special reference to autophagy and lysosomal cathepsins. Arch Histol Cytol 1998, 61: 395-403.
34. Xue L, Fletcher GC, Tolkovsky AM. Autophagy is activated by apoptotic signalling in sympathetic neurons: an alternative mechanism of death execution. Mol Cell Neurosci 1999, 14: 180-198.
35. Gozuacik D, Kimchi A. Autophagy as a cell death and tumor suppressor mechanism. Oncogene 2004, 23: 2891-2906.
36. Shimizu S, Kanaseki T, Mizushima N, Mizuta T, Arakawa-Kobayashi S, Thompson CB, et al. Role of Bcl-2 family proteins in a non-apoptotic programmed cell death dependent on autophagy genes. Nat Cell Biol 2004, 6: 1221-1228.
37. Thorburn J, Moore F, Rao A, Barclay WW, Thomas LR, Grant KW, et al. Selective inactivation of a Fas-associated death domain protein (FADD)-dependent apoptosis and autophagy pathway in immortal epithelial cells. Mol Biol Cell 2005, 16: 1189-1199.
38. Scarlatti F, Bauvy C, Ventruti A, Sala G, Cluzeaud F, Vandewalle A, et al. Ceramide-mediated macroautophagy involves inhibition of protein kinase B and up-regulation of beclin 1. J Biol Chem 2004, 279: 18384-18391.
39. Inbal B, Bialik S, Sabanay I, Shani G, Kimchi A. DAP kinase and DRP-1 mediate membrane blebbing and the formation of autophagic vesicles during programmed cell death. J Cell Biol 2002, 157: 455-468.
40. Cardenas-Aguayo Mdel C, Santa-Olalla J, Baizabal JM, Salgado LM, Covarrubias L. Growth factor deprivation induces an alternative non-apoptotic death mechanism that is inhibited by Bcl-2 in cells derived from neural precursor cells. J Hematother Stem Cell Res 2003, 12: 735-748.
41. Lee JM, Zipfel GJ, Choi DW. The changing landscape of ischemic brain injury mechanisms. Nature 1999, 399(6738 Suppl): A7-A14.
42. Seyfried DM, Veyna R, Han Y, Li K, Tang N, Betts RL, et al. A selective cysteine protease inhibitor is non-toxic and cerebroprotective in rats undergoing transient middle cerebral artery ischemia. Brain Res 2001, 901: 94-101.
43. Tsubokawa T, Yamaguchi-Okada M, Calvert JW, Solaroglu I, Shimamura N, Yata K, et al. Neurovascular and neuronal protection by E64d after focal cerebral ischemia in rats. J Neurosci Res 2006, 84: 832-840.
44. Yoshida M, Yamashima T, Zhao L, Tsuchiya K, Kohda Y, Tonchev AB, et al. Primate neurons show different vulnerability to transient ischemia and response to cathepsin inhibition. Acta Neuropathol 2002, 104: 267-272.
45. Luke CJ, Pak SC, Askew YS, Naviglia TL, Askew DJ, Nobar SM, et al. An intracellular serpin regulates necrosis by inhibiting the induction and sequelae of lysosomal injury. Cell 2007, 130: 1108-1119.