메뉴 건너뛰기




Volumn 85, Issue 6, 2003, Pages 1402-1411

Brain edema induced by in vitro ischemia: Causal factors and neuroprotection

Author keywords

Brain slices; Ca2+; Cerebral edema; Excitotoxicity; Mitochondria; Oxidative stress

Indexed keywords

2 [2 [4 (4 NITROBENZYLOXY)PHENYL]ETHYL]ISOTHIOUREA METHANESULFONATE; 2 AMINO 5 PHOSPHONOVALERIC ACID; 6 CYANO 7 NITRO 2,3 QUINOXALINEDIONE; ASCORBIC ACID; CYCLOSPORIN A; DIMETHYLUREA; GLUCOSE; GLUTAMATE RECEPTOR ANTAGONIST; OXYGEN; REACTIVE OXYGEN METABOLITE; TACROLIMUS; TEMPOL; TROLOX C;

EID: 0038810306     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.2003.01772.x     Document Type: Article
Times cited : (103)

References (85)
  • 1
    • 0033913949 scopus 로고    scopus 로고
    • Mitochondrial and intrinsic optical signals imaged during hypoxia and spreading depression in rat hippocampal slices
    • Bahar S., Fayuk D., Somjen G. G. and Aitken P. G. and Turner D. A. (2000) Mitochondrial and intrinsic optical signals imaged during hypoxia and spreading depression in rat hippocampal slices. J. Neurophysiol. 84, 311-324.
    • (2000) J. Neurophysiol. , vol.84 , pp. 311-324
    • Bahar, S.1    Fayuk, D.2    Somjen, G.G.3    Aitken, P.G.4    Turner, D.A.5
  • 2
    • 0023103464 scopus 로고
    • Double-blind randomised trial of intravenous glycerol in acute stroke
    • Bayer A. J., Pathy M. S. and Newcombe R. (1987) Double-blind randomised trial of intravenous glycerol in acute stroke. Lancet 1, 405-408.
    • (1987) Lancet , vol.1 , pp. 405-408
    • Bayer, A.J.1    Pathy, M.S.2    Newcombe, R.3
  • 3
    • 0033761104 scopus 로고    scopus 로고
    • Cochran Report: A systematic review of mannitol therapy for acute ischemic stroke and cerebral parenchymal hemorrhage
    • Bereczki D., Liu M., do Prado G. F. and Fekete I. (2000) Cochran Report: a systematic review of mannitol therapy for acute ischemic stroke and cerebral parenchymal hemorrhage. Stroke 31, 2719-2722.
    • (2000) Stroke , vol.31 , pp. 2719-2722
    • Bereczki, D.1    Liu, M.2    Do Prado, G.F.3    Fekete, I.4
  • 4
    • 0034535252 scopus 로고    scopus 로고
    • Quantitative biochemical and ultrastructural comparison of mitochondrial permeability transition in isolated brain and liver mitochondria: Evidence for reduced sensitivity of brain mitochondria
    • Berman S. B., Watkins S. C. and Hastings T. G. (2000) Quantitative biochemical and ultrastructural comparison of mitochondrial permeability transition in isolated brain and liver mitochondria: evidence for reduced sensitivity of brain mitochondria. Exp. Neurol. 164, 415-425.
    • (2000) Exp. Neurol. , vol.164 , pp. 415-425
    • Berman, S.B.1    Watkins, S.C.2    Hastings, T.G.3
  • 5
    • 0035870630 scopus 로고    scopus 로고
    • Calcium dependence of rapid astrocyte death induced by transient hypoxia, acidosis, and extra-cellular ion shifts
    • Bondarenko A. and Chesler M. (2001) Calcium dependence of rapid astrocyte death induced by transient hypoxia, acidosis, and extra-cellular ion shifts. Glia 34, 143-149.
    • (2001) Glia , vol.34 , pp. 143-149
    • Bondarenko, A.1    Chesler, M.2
  • 6
    • 0019455594 scopus 로고
    • Mechanisms and timing of deaths from cerebral infarction
    • Bounds J. V., Wiebers D. O., Whisnant J. P. and Okazaki H. (1981) Mechanisms and timing of deaths from cerebral infarction. Stroke 12, 474-477.
    • (1981) Stroke , vol.12 , pp. 474-477
    • Bounds, J.V.1    Wiebers, D.O.2    Whisnant, J.P.3    Okazaki, H.4
  • 9
    • 0000279124 scopus 로고
    • The effect of prolonged hypothermia and mannitol infusion upon the neurologic sequelae of total cerebral ischemia
    • Brient B. W., Zimmerman J. M. and King T. C. (1965) The effect of prolonged hypothermia and mannitol infusion upon the neurologic sequelae of total cerebral ischemia. Surg. Forum 16, 407-408.
    • (1965) Surg. Forum , vol.16 , pp. 407-408
    • Brient, B.W.1    Zimmerman, J.M.2    King, T.C.3
  • 10
    • 0023887866 scopus 로고
    • Oxygen free radical involvement in ischemia and reperfusion injury to brain
    • Cao W., Carney J. M., Duchon A., Floyd R. A. and Chevion M. (1988) Oxygen free radical involvement in ischemia and reperfusion injury to brain. Neurosci. Lett. 88, 233-238.
    • (1988) Neurosci. Lett. , vol.88 , pp. 233-238
    • Cao, W.1    Carney, J.M.2    Duchon, A.3    Floyd, R.A.4    Chevion, M.5
  • 11
    • 0020067944 scopus 로고
    • Phospholipid degradation and cellular edema induced by free radicals in brain cortical slices
    • Chan P. H., Yurko M. and Fishman R. A. (1982) Phospholipid degradation and cellular edema induced by free radicals in brain cortical slices. J. Neurochem. 38, 525-531.
    • (1982) J. Neurochem. , vol.38 , pp. 525-531
    • Chan, P.H.1    Yurko, M.2    Fishman, R.A.3
  • 12
    • 0035449886 scopus 로고    scopus 로고
    • 2+ and ATP in native reactive astrocytes from adult rat brain
    • 2+ and ATP in native reactive astrocytes from adult rat brain. J. Neurosci. 21, 6512-6521.
    • (2001) J. Neurosci. , vol.21 , pp. 6512-6521
    • Chen, M.1    Simard, J.M.2
  • 13
    • 0023137252 scopus 로고
    • Ionic dependence of glutamate neurotoxicity
    • Choi D. W. (1987) Ionic dependence of glutamate neurotoxicity. J. Neurosci. 7, 369-379.
    • (1987) J. Neurosci. , vol.7 , pp. 369-379
    • Choi, D.W.1
  • 14
    • 0028118703 scopus 로고
    • Trolox attenuates cortical neuronal injury induced by iron, ultraviolet light, glucose deprivation, or AMPA
    • Chow H. S., Lynch J. J., 3rd Rose K. and Choi D. W. (1994) Trolox attenuates cortical neuronal injury induced by iron, ultraviolet light, glucose deprivation, or AMPA. Brain Res. 639, 102-108.
    • (1994) Brain Res. , vol.639 , pp. 102-108
    • Chow, H.S.1    Lynch J.J. III2    Rose, K.3    Choi, D.W.4
  • 15
    • 0028650399 scopus 로고
    • Enzymatic/nonenzymatic sources of oxyradicals and regulation of antioxidant defenses
    • Cohen G. (1994) Enzymatic/nonenzymatic sources of oxyradicals and regulation of antioxidant defenses. Ann. NY Acad. Sci. 738, 8-15.
    • (1994) Ann. NY Acad. Sci. , vol.738 , pp. 8-15
    • Cohen, G.1
  • 16
    • 0028075423 scopus 로고
    • Recruitment of mitochondrial cyclophilin to the mitochondrial outer membrane under conditions of oxidative stress that enhance the opening of a calcium-sensifive non-specific channel
    • Connem C. P. and Halestrap A. P. (1994) Recruitment of mitochondrial cyclophilin to the mitochondrial outer membrane under conditions of oxidative stress that enhance the opening of a calcium-sensifive non-specific channel. Biochem. J. 302, 321-324.
    • (1994) Biochem. J. , vol.302 , pp. 321-324
    • Connem, C.P.1    Halestrap, A.P.2
  • 17
    • 0026076810 scopus 로고
    • Extracellular volume decreases while cell volume is maintained by ion uptake in rat brain during acute hypematremia
    • Cserr H. F., DePasquale M., Nicholson C., Patlak C. S., Pettigrew K. D. and Rice M. E. (1991) Extracellular volume decreases while cell volume is maintained by ion uptake in rat brain during acute hypematremia. J. Physiol. (Lond.) 442, 277-295.
    • (1991) J. Physiol. (Lond.) , vol.442 , pp. 277-295
    • Cserr, H.F.1    DePasquale, M.2    Nicholson, C.3    Patlak, C.S.4    Pettigrew, K.D.5    Rice, M.E.6
  • 18
    • 0036319443 scopus 로고    scopus 로고
    • + in NMDA excitotoxicity in glucose-deprived and depolarized cerebellar granule cells
    • + in NMDA excitotoxicity in glucose-deprived and depolarized cerebellar granule cells. J. Neurochem. 81, 379-389.
    • (2002) J. Neurochem. , vol.81 , pp. 379-389
    • Czyz, A.1    Baranauskas, G.2    Kiedrowski, L.3
  • 19
    • 0344560643 scopus 로고    scopus 로고
    • Neurological deterioration in acute ischemic stroke: Potential predictors and associated factors in the European cooperative acute stroke study (ECASS) I
    • Davalos A., Toni D., Iweins F., Lesaffre E., Bastianello S. and Castillo J. (1999) Neurological deterioration in acute ischemic stroke: potential predictors and associated factors in the European cooperative acute stroke study (ECASS) I. Stroke 30, 2631-2636.
    • (1999) Stroke , vol.30 , pp. 2631-2636
    • Davalos, A.1    Toni, D.2    Iweins, F.3    Lesaffre, E.4    Bastianello, S.5    Castillo, J.6
  • 20
    • 0035451524 scopus 로고    scopus 로고
    • Neuro-protective adaptations in hibernation: Therapeutic implications for ischemia-reperfusion, traumatic brain injury and neurodegenerative diseases
    • Drew K. L., Rice M. E., Kuhn T. B. and Smith M. A. (2001) Neuro-protective adaptations in hibernation: therapeutic implications for ischemia-reperfusion, traumatic brain injury and neurodegenerative diseases. Free. Rad. Biol. Med. 31, 563-573.
    • (2001) Free. Rad. Biol. Med. , vol.31 , pp. 563-573
    • Drew, K.L.1    Rice, M.E.2    Kuhn, T.B.3    Smith, M.A.4
  • 23
    • 0033253497 scopus 로고    scopus 로고
    • The puzzle of neuronal death and life: Is mannitol the right drug for the treatment of brain edema associated with ischaemic stroke?
    • Famularo G. (1999) The puzzle of neuronal death and life: is mannitol the right drug for the treatment of brain edema associated with ischaemic stroke? Eur. J. Emerg. Med. 6, 363-368.
    • (1999) Eur. J. Emerg. Med. , vol.6 , pp. 363-368
    • Famularo, G.1
  • 24
    • 0035890197 scopus 로고    scopus 로고
    • Dynamics of intracellular calcium and free radical production during ischemia in pyramidal neurons
    • Frantseva M. V., Carlen P. L. and Perez Velazquez J. L. (2001) Dynamics of intracellular calcium and free radical production during ischemia in pyramidal neurons. Free Rad. Biol. Med. 31, 1216-1227.
    • (2001) Free Rad. Biol. Med. , vol.31 , pp. 1216-1227
    • Frantseva, M.V.1    Carlen, P.L.2    Perez Velazquez, J.L.3
  • 25
    • 0036479054 scopus 로고    scopus 로고
    • Mitochondrial permeability transition in acute neurodegeneration
    • Friberg H. and Wieloch T. (2002) Mitochondrial permeability transition in acute neurodegeneration. Biochimie 84, 241-250.
    • (2002) Biochimie , vol.84 , pp. 241-250
    • Friberg, H.1    Wieloch, T.2
  • 26
    • 0032528154 scopus 로고    scopus 로고
    • Cyclosporin A, but not FK 506, protects mitochondria and neurons against hypoglycemic damage and implicates the mitochondrial permeability transition in cell death
    • Friberg H., Ferrand-Drake M., Bengtsson F., Halestrap A. P. and Wieloch T. (1998) Cyclosporin A, but not FK 506, protects mitochondria and neurons against hypoglycemic damage and implicates the mitochondrial permeability transition in cell death. J. Neurosci. 18, 5151-5159.
    • (1998) J. Neurosci. , vol.18 , pp. 5151-5159
    • Friberg, H.1    Ferrand-Drake, M.2    Bengtsson, F.3    Halestrap, A.P.4    Wieloch, T.5
  • 27
    • 0029914446 scopus 로고    scopus 로고
    • Malignant middle cerebral artery infarction: Clinical course and prognostic signs
    • Hacke W., Schwab S., Horn M., Spranger M., De Georgia M. and von Kummer R. (1996) Malignant middle cerebral artery infarction: clinical course and prognostic signs. Arch. Neurol. 53, 309-315.
    • (1996) Arch. Neurol. , vol.53 , pp. 309-315
    • Hacke, W.1    Schwab, S.2    Horn, M.3    Spranger, M.4    De Georgia, M.5    Von Kummer, R.6
  • 29
    • 0021981842 scopus 로고
    • Effect of anoxia on ion distribution in the brain
    • Hansen A. J. (1985) Effect of anoxia on ion distribution in the brain. Physiol. Rev. 65, 101-148.
    • (1985) Physiol. Rev. , vol.65 , pp. 101-148
    • Hansen, A.J.1
  • 31
    • 0027932457 scopus 로고
    • Selective potentiation of NMDA-induced neuronal injury following induction of astrocytic iNOS
    • Hewett S. J., Csernansky C. A. and Choi D. W. (1994) Selective potentiation of NMDA-induced neuronal injury following induction of astrocytic iNOS. Neuron 13, 487-494.
    • (1994) Neuron , vol.13 , pp. 487-494
    • Hewett, S.J.1    Csernansky, C.A.2    Choi, D.W.3
  • 33
    • 0036138264 scopus 로고    scopus 로고
    • Water compartmentalization and spread of ischemic injury in thick-slice ischemia model
    • Hrabětová S., Chen K. C., Masri D. and Nicholson C. (2002) Water compartmentalization and spread of ischemic injury in thick-slice ischemia model. J. Cereb. Blood Flow Metab. 22, 80-88.
    • (2002) J. Cereb. Blood Flow Metab. , vol.22 , pp. 80-88
    • Hrabětová, S.1    Chen, K.C.2    Masri, D.3    Nicholson, C.4
  • 34
    • 0034986981 scopus 로고    scopus 로고
    • Up-regulation of TNF-alpha convertase (TACE/ADAM17) after oxygen-glucose deprivation in rat forebrain slices
    • Hurtado O., Cardenas A., Lizasoain I., Bosca L., Leza J. C., Lorenzo P. and Moro M. A. (2001) Up-regulation of TNF-alpha convertase (TACE/ADAM17) after oxygen-glucose deprivation in rat forebrain slices. Neuropharmacology 40, 1094-1102.
    • (2001) Neuropharmacology , vol.40 , pp. 1094-1102
    • Hurtado, O.1    Cardenas, A.2    Lizasoain, I.3    Bosca, L.4    Leza, J.C.5    Lorenzo, P.6    Moro, M.A.7
  • 36
    • 0035094866 scopus 로고    scopus 로고
    • Anoxic, depolarization mediates acute damage independent of glutamate in neocortical brain slices
    • Jarvis C. R., Anderson T. R. and Andrew R. D. (2001) Anoxic, depolarization mediates acute damage independent of glutamate in neocortical brain slices. Cereb. Cortex 11, 249-259.
    • (2001) Cereb. Cortex , vol.11 , pp. 249-259
    • Jarvis, C.R.1    Anderson, T.R.2    Andrew, R.D.3
  • 37
    • 0031041262 scopus 로고    scopus 로고
    • Mechanisms that result in damage during and following cerebral ischemia
    • Juurlink B. H. and Sweeney M. I. (1997) Mechanisms that result in damage during and following cerebral ischemia. Neurosci. Biobehav. Rev. 21, 121-128.
    • (1997) Neurosci. Biobehav. Rev. , vol.21 , pp. 121-128
    • Juurlink, B.H.1    Sweeney, M.I.2
  • 39
    • 0024785709 scopus 로고
    • Oxygen radicals in CNS damage
    • Kontos H. A. (1989) Oxygen radicals in CNS damage. Chem.-Biol. Interact. 72, 229-255.
    • (1989) Chem.-Biol. Interact. , vol.72 , pp. 229-255
    • Kontos, H.A.1
  • 40
    • 0023801195 scopus 로고
    • Functional recovery after decompressive craneitomy for cerebral infraction
    • Konzdiola D. and Fazl M. (1988) Functional recovery after decompressive craneitomy for cerebral infraction. Neurosurgery 23, 143-147.
    • (1988) Neurosurgery , vol.23 , pp. 143-147
    • Konzdiola, D.1    Fazl, M.2
  • 41
    • 0033965533 scopus 로고    scopus 로고
    • Regional differences in hypoxic depolarization and swelling in hippocampal slices
    • Kreisman N. R., Soliman S. and Gozal D. (2000) Regional differences in hypoxic depolarization and swelling in hippocampal slices. J. Neurophysiol. 83, 1031-1038.
    • (2000) J. Neurophysiol. , vol.83 , pp. 1031-1038
    • Kreisman, N.R.1    Soliman, S.2    Gozal, D.3
  • 42
    • 0033600482 scopus 로고    scopus 로고
    • The immunosuppressants cyclosporin A and FK506 equally ameliorate brain damage due to 30-min middle cerebral artery occlusion in hyperglycemic rats
    • Kuroda S. and Janelidze S. and Siesjo B. K. (1999) The immunosuppressants cyclosporin A and FK506 equally ameliorate brain damage due to 30-min middle cerebral artery occlusion in hyperglycemic rats. Brain Res. 835, 148-153.
    • (1999) Brain Res. , vol.835 , pp. 148-153
    • Kuroda, S.1    Janelidze, S.2    Siesjo, B.K.3
  • 43
    • 0027380609 scopus 로고
    • Nitric oxide, superoxide and peroxynitrite: Putative mediators of NMDA-induced cell death in cerebellar granule cells
    • Lafon-Cazal M., Culcasi M., Gaven F., Pietri S. and Bockaert J. (1993) Nitric oxide, superoxide and peroxynitrite: putative mediators of NMDA-induced cell death in cerebellar granule cells. Neuropharmacology 32, 1259-1266.
    • (1993) Neuropharmacology , vol.32 , pp. 1259-1266
    • Lafon-Cazal, M.1    Culcasi, M.2    Gaven, F.3    Pietri, S.4    Bockaert, J.5
  • 45
    • 0032845121 scopus 로고    scopus 로고
    • Ischemic cell death in brain neurons
    • Lipton P. (1999) Ischemic cell death in brain neurons. Physiol. Rev. 79, 1431-1568.
    • (1999) Physiol. Rev. , vol.79 , pp. 1431-1568
    • Lipton, P.1
  • 46
    • 0035804786 scopus 로고    scopus 로고
    • Effects of ion channel blockade on the distribution of Na, K, Ca and other elements in oxygen-glucose deprived CA1 hippocampal neurons
    • LoPachin R. M., Gaughan C. L., Lehning E. J., Weber M. L. and Taylor C. P. (2001) Effects of ion channel blockade on the distribution of Na, K, Ca and other elements in oxygen-glucose deprived CA1 hippocampal neurons. Neuroscience 103, 971-983.
    • (2001) Neuroscience , vol.103 , pp. 971-983
    • LoPachin, R.M.1    Gaughan, C.L.2    Lehning, E.J.3    Weber, M.L.4    Taylor, C.P.5
  • 47
    • 0032924640 scopus 로고    scopus 로고
    • Oxidative stress in brain ischemia
    • Love S. (1999) Oxidative stress in brain ischemia. Brain Pathol. 9, 119-131.
    • (1999) Brain Pathol. , vol.9 , pp. 119-131
    • Love, S.1
  • 48
    • 0032941253 scopus 로고    scopus 로고
    • Potential role of calcineurin for brain ischemia and traumatic injury
    • Morioka M., Hamada J., Ushio Y. and Miyamoto E. (1999) Potential role of calcineurin for brain ischemia and traumatic injury. Prog. Neurobiol. 58, 1-30.
    • (1999) Prog. Neurobiol. , vol.58 , pp. 1-30
    • Morioka, M.1    Hamada, J.2    Ushio, Y.3    Miyamoto, E.4
  • 49
    • 0034176843 scopus 로고    scopus 로고
    • Mitochondrial membrane potential and neuronal glutamate excitotoxicity: Mortality and millivolts
    • Nicholls D. G. and Ward M. W. (2000) Mitochondrial membrane potential and neuronal glutamate excitotoxicity: mortality and millivolts. Trends Neurosci. 23, 166-174.
    • (2000) Trends Neurosci. , vol.23 , pp. 166-174
    • Nicholls, D.G.1    Ward, M.W.2
  • 51
    • 0025923211 scopus 로고
    • Interaction between free radicals and excitatory amino acids in the formation of ischemic brain edema in rats
    • Oh S. M. and Betz A. L. (1991) Interaction between free radicals and excitatory amino acids in the formation of ischemic brain edema in rats. Stroke 22, 915-921.
    • (1991) Stroke , vol.22 , pp. 915-921
    • Oh, S.M.1    Betz, A.L.2
  • 52
    • 0031012574 scopus 로고    scopus 로고
    • Osmotherapy: Basic concepts and controversies
    • Paczynski R. P. (1997) Osmotherapy: basic concepts and controversies. Crit. Care Clin. 13, 105-129.
    • (1997) Crit. Care Clin. , vol.13 , pp. 105-129
    • Paczynski, R.P.1
  • 53
    • 0028195028 scopus 로고
    • Pretreatment with a competitive NMDA antagonist D-CPPene attenuates focal cerebral infarction and brain swelling in awake rats
    • Park C. K., McCulloch J., Kang J. K. and Choi C. R. (1994) Pretreatment with a competitive NMDA antagonist D-CPPene attenuates focal cerebral infarction and brain swelling in awake rats. Acta Neurochir. (Wien) 127, 220-226.
    • (1994) Acta Neurochir. (Wien) , vol.127 , pp. 220-226
    • Park, C.K.1    McCulloch, J.2    Kang, J.K.3    Choi, C.R.4
  • 54
    • 0031826377 scopus 로고    scopus 로고
    • Hypoglycemia, hypoxia, and ischemia in a corticostriatal slice preparation: Electrophysiologic changes and ascorbyl radical formation
    • Pedersen J. Z., Bernardi G., Centonze D., Pisani A., Rossi L., Rotilio G. and Calabresi P. (1998) Hypoglycemia, hypoxia, and ischemia in a corticostriatal slice preparation: electrophysiologic changes and ascorbyl radical formation. J. Cereb. Blood Flow Metab. 18, 868-875.
    • (1998) J. Cereb. Blood Flow Metab. , vol.18 , pp. 868-875
    • Pedersen, J.Z.1    Bernardi, G.2    Centonze, D.3    Pisani, A.4    Rossi, L.5    Rotilio, G.6    Calabresi, P.7
  • 55
    • 0000236120 scopus 로고    scopus 로고
    • In vitro ischemia promotes glutamate-mediated free radical generation and intracellular calcium accumulation in hippocampal pyramidal neurons
    • Perez Velazquez J. L., Frantseva M. V. and Carlen P. L. (1997) In vitro ischemia promotes glutamate-mediated free radical generation and intracellular calcium accumulation in hippocampal pyramidal neurons. J. Neurosci. 17, 9085-9094.
    • (1997) J. Neurosci. , vol.17 , pp. 9085-9094
    • Perez Velazquez, J.L.1    Frantseva, M.V.2    Carlen, P.L.3
  • 56
    • 0029093894 scopus 로고
    • Extracellular potassium, volume fraction, and tortuosity in rat hippocampal CA1, CA3, and cortical slices during ischemia
    • Pérez-Pinzón M. A., Tao L. and Nicholson C. (1995) Extracellular potassium, volume fraction, and tortuosity in rat hippocampal CA1, CA3, and cortical slices during ischemia. J. Neurophysiol. 74, 565-573.
    • (1995) J. Neurophysiol. , vol.74 , pp. 565-573
    • Pérez-Pinzón, M.A.1    Tao, L.2    Nicholson, C.3
  • 57
    • 0343247698 scopus 로고    scopus 로고
    • Antioxidants, mitochondrial hyperoxidation and electrical recovery after anoxia in hippocampal slices
    • Pérez-Pinzón M. A., Mumford P. L., Rosenthal M. and Sick T. J. (1997) Antioxidants, mitochondrial hyperoxidation and electrical recovery after anoxia in hippocampal slices. Brain. Res. 754, 163-170.
    • (1997) Brain. Res. , vol.754 , pp. 163-170
    • Pérez-Pinzón, M.A.1    Mumford, P.L.2    Rosenthal, M.3    Sick, T.J.4
  • 58
    • 0035914207 scopus 로고    scopus 로고
    • 2+ exchange by KB-R7943, a novel selective antagonist, attenuates phosphoethanolamine and free fatty acid efflux in rat cerebral cortex during ischemia-reperfusion injury
    • 2+ exchange by KB-R7943, a novel selective antagonist, attenuates phosphoethanolamine and free fatty acid efflux in rat cerebral cortex during ischemia-reperfusion injury. Brain. Res. 916, 192-198.
    • (2001) Brain. Res. , vol.916 , pp. 192-198
    • Pilitsis, J.G.1    Diaz, F.G.2    O'Regan, M.H.3    Phillis, J.W.4
  • 59
    • 0031891837 scopus 로고    scopus 로고
    • Mitochondrial transmembrane potential and free radical production in excitotoxic neurodegeneration
    • Prehn J. H. (1998) Mitochondrial transmembrane potential and free radical production in excitotoxic neurodegeneration. Naunyn Schmied. Arch. Pharmaco. 1, 316-322.
    • (1998) Naunyn Schmied. Arch. Pharmaco. , vol.1 , pp. 316-322
    • Prehn, J.H.1
  • 60
    • 0035449974 scopus 로고    scopus 로고
    • The mitochondrial permeability transition pore and nitric oxide synthase mediate early mitochondrial depolarization in astrocytes during oxygen-glucose deprivation
    • Reichert S. A., Kim-Han J. S. and Dugan L. L. (2001) The mitochondrial permeability transition pore and nitric oxide synthase mediate early mitochondrial depolarization in astrocytes during oxygen-glucose deprivation. J. Neurosci. 21, 6608-6616.
    • (2001) J. Neurosci. , vol.21 , pp. 6608-6616
    • Reichert, S.A.1    Kim-Han, J.S.2    Dugan, L.L.3
  • 61
    • 0033647043 scopus 로고    scopus 로고
    • Role of glycerol in cerebrovascular disease
    • Restrepo L. and Balish M. (2000) Role of glycerol in cerebrovascular disease. Neurologist 6, 338-347.
    • (2000) Neurologist , vol.6 , pp. 338-347
    • Restrepo, L.1    Balish, M.2
  • 62
    • 0029064518 scopus 로고
    • Glutamate induces the production of reactive oxygen species in cultured forebrain neurons following NMDA receptor activation
    • Reynolds I. J. and Hastings T. G. (1995) Glutamate induces the production of reactive oxygen species in cultured forebrain neurons following NMDA receptor activation. J. Neurosci. 15, 3318-3327.
    • (1995) J. Neurosci. , vol.15 , pp. 3318-3327
    • Reynolds, I.J.1    Hastings, T.G.2
  • 63
    • 0032853938 scopus 로고    scopus 로고
    • The use of ascorbate in preparation and maintenance of brain slices
    • Rice M. E. (1999) The use of ascorbate in preparation and maintenance of brain slices. Methods 18, 144-149.
    • (1999) Methods , vol.18 , pp. 144-149
    • Rice, M.E.1
  • 64
    • 0034194081 scopus 로고    scopus 로고
    • Ascorbate regulation and its neuroprotective role in the brain
    • Rice M. E. (2000) Ascorbate regulation and its neuroprotective role in the brain. Trends Neurosci. 23, 209-216.
    • (2000) Trends Neurosci. , vol.23 , pp. 209-216
    • Rice, M.E.1
  • 65
    • 0029101753 scopus 로고
    • Decompressive surgery in space-occupying hemispheric infarction: Results of an open, prospective trial
    • Rieke K., Schwab S., Kreiger D., von Kummer R., Aschoff A., Schuchardt V. and Hacke W. (1995) Decompressive surgery in space-occupying hemispheric infarction: results of an open, prospective trial. Crit. Care Med. 23, 1576-1587.
    • (1995) Crit. Care Med. , vol.23 , pp. 1576-1587
    • Rieke, K.1    Schwab, S.2    Kreiger, D.3    Von Kummer, R.4    Aschoff, A.5    Schuchardt, V.6    Hacke, W.7
  • 67
    • 0031921894 scopus 로고    scopus 로고
    • Incidence of space-occupying brain edema following sytemic thrombolysis of acute supratentorial ischemia
    • Rudolf J., Grond M., Stenzel C., Neveling M. and Heiss W. D. (1998) Incidence of space-occupying brain edema following sytemic thrombolysis of acute supratentorial ischemia. Cerebrovasc. Dis. 8, 166-167.
    • (1998) Cerebrovasc. Dis. , vol.8 , pp. 166-167
    • Rudolf, J.1    Grond, M.2    Stenzel, C.3    Neveling, M.4    Heiss, W.D.5
  • 68
    • 0032589229 scopus 로고    scopus 로고
    • 2+ exchange inhibitor KB-R7943 protects CA1 neurons in rat hippocampal slices against hypoxic/hypoglycemic injury
    • 2+ exchange inhibitor KB-R7943 protects CA1 neurons in rat hippocampal slices against hypoxic/hypoglycemic injury. Neuropharmacology 38, 319-321.
    • (1999) Neuropharmacology , vol.38 , pp. 319-321
    • Schröder, U.H.1    Breder, J.2    Sabelhaus, C.F.3    Reymann, K.G.4
  • 69
    • 0024356046 scopus 로고
    • Cerebral ischemia revisited: New insights as revealed using in vitro brain slice preparations
    • Schurr A. and Rigor B. M. (1989) Cerebral ischemia revisited: new insights as revealed using in vitro brain slice preparations. Experientia 45, 684-695.
    • (1989) Experientia , vol.45 , pp. 684-695
    • Schurr, A.1    Rigor, B.M.2
  • 70
    • 0032867431 scopus 로고    scopus 로고
    • Study of cerebral energy metabolism in rat hippocampal slice preparation
    • Schurr A., Payne R. S., Miller J. J. and Rigor B. M. (1999) Study of cerebral energy metabolism in rat hippocampal slice preparation. Methods 18, 117-126.
    • (1999) Methods , vol.18 , pp. 117-126
    • Schurr, A.1    Payne, R.S.2    Miller, J.J.3    Rigor, B.M.4
  • 71
    • 0029810018 scopus 로고    scopus 로고
    • The value of intracranial pressure monitoring in acute hemispheric stroke
    • Schwab S., Aschoff A., Spranger M., Albert F. and Hacke W. (1996) The value of intracranial pressure monitoring in acute hemispheric stroke. Neurology 47, 393-398.
    • (1996) Neurology , vol.47 , pp. 393-398
    • Schwab, S.1    Aschoff, A.2    Spranger, M.3    Albert, F.4    Hacke, W.5
  • 72
    • 0027258164 scopus 로고
    • Ischemia/reperfusion-induced injury of forebrain mitochondria and protection by ascorbate
    • Sciamanna M. A. and Lee C. P. (1993) Ischemia/reperfusion-induced injury of forebrain mitochondria and protection by ascorbate. Arch. Biochem. Biophys. 305, 215-224.
    • (1993) Arch. Biochem. Biophys. , vol.305 , pp. 215-224
    • Sciamanna, M.A.1    Lee, C.P.2
  • 73
    • 0019311239 scopus 로고
    • Cerebral edema in a stroke: A common, often fatal complication
    • Sherman D. G. and Easton J. D. (1980) Cerebral edema in a stroke: a common, often fatal complication. Postgrad. Med. 68, 107-120.
    • (1980) Postgrad. Med. , vol.68 , pp. 107-120
    • Sherman, D.G.1    Easton, J.D.2
  • 74
    • 0342313052 scopus 로고
    • Forward
    • Staub C. C. and Taylor A. E., eds, Raven Press, New York
    • Staub C. C. and Taylor A. E. (1984) Forward, in Edema (Staub C. C. and Taylor A. E., eds), pp. v. Raven Press, New York.
    • (1984) Edema
    • Staub, C.C.1    Taylor, A.E.2
  • 75
    • 0035845699 scopus 로고    scopus 로고
    • Treatment options for large hemispheric stroke
    • Steiner T., Ringleb P. and Hacke W. (2001) Treatment options for large hemispheric stroke. Neurology 57, S61-S68.
    • (2001) Neurology , vol.57
    • Steiner, T.1    Ringleb, P.2    Hacke, W.3
  • 76
    • 0034867346 scopus 로고    scopus 로고
    • Effects of tacrolimus on hemispheric water content and cerebrospinal fluid levels of glutamate, hypoxanthine, interleukin-6, and tumor necrosis factor-alpha following controlled cortical impact injury in rats
    • Stover J. F., Schoning B., Sakowitz O. W., Woiciechowsky C. and Unterberg A. W. (2001) Effects of tacrolimus on hemispheric water content and cerebrospinal fluid levels of glutamate, hypoxanthine, interleukin-6, and tumor necrosis factor-alpha following controlled cortical impact injury in rats. J. Neurosurg. 94, 782-787.
    • (2001) J. Neurosurg. , vol.94 , pp. 782-787
    • Stover, J.F.1    Schoning, B.2    Sakowitz, O.W.3    Woiciechowsky, C.4    Unterberg, A.W.5
  • 77
    • 0344065373 scopus 로고    scopus 로고
    • Recommendations for standards regarding preclinical neuroprotective and restorative drug development
    • Stroke Therapy Academic Industry Roundtable (STAIR) (1999) Recommendations for standards regarding preclinical neuroprotective and restorative drug development. Stroke 30, 2752-2758.
    • (1999) Stroke , vol.30 , pp. 2752-2758
  • 78
    • 0025925116 scopus 로고
    • 2+ influx during anoxia in mammalian central nervous system white matter
    • 2+ influx during anoxia in mammalian central nervous system white matter. Ann. Neurol. 30, 375-380.
    • (1991) Ann. Neurol. , vol.30 , pp. 375-380
    • Stys, P.K.1    Waxman, S.G.2    Ransom, B.R.3
  • 79
    • 0036403825 scopus 로고    scopus 로고
    • Differential neuroprotection by cyclosporin a and FK506 following ischemia corresponds with differing abilities to inhibit calcineurin and the mitochondrial permeability transition
    • Uchino H., Minamikawa-Tachino R., Kristian T., Perkins G., Narazaki M., Siesjo B. and Shibasaki F. (2002) Differential neuroprotection by cyclosporin a and FK506 following ischemia corresponds with differing abilities to inhibit calcineurin and the mitochondrial permeability transition. Neurobiol. Dis. 10, 219-233.
    • (2002) Neurobiol. Dis. , vol.10 , pp. 219-233
    • Uchino, H.1    Minamikawa-Tachino, R.2    Kristian, T.3    Perkins, G.4    Narazaki, M.5    Siesjo, B.6    Shibasaki, F.7
  • 80
    • 0035865259 scopus 로고    scopus 로고
    • Exploration of the role of reactive oxygen species in glutamate toxicity in rat hippocampal neurons in culture
    • Vergun O., Sobolevsky A. I., Yelshansky M. V., Keelan J., Khodorov B. I. and Duchen M. R. (2001) Exploration of the role of reactive oxygen species in glutamate toxicity in rat hippocampal neurons in culture. J. Physiol. (Lond.) 531, 147-163.
    • (2001) J. Physiol. (Lond.) , vol.531 , pp. 147-163
    • Vergun, O.1    Sobolevsky, A.I.2    Yelshansky, M.V.3    Keelan, J.4    Khodorov, B.I.5    Duchen, M.R.6
  • 81
    • 0025871727 scopus 로고
    • Enhancement of NMDA receptor-mediated neurotoxicity in the hippocampal slice by depolarization and ischemia
    • Vornov J. J. and Coyle J. T. (1991) Enhancement of NMDA receptor-mediated neurotoxicity in the hippocampal slice by depolarization and ischemia. Brain Res. 555, 99-106.
    • (1991) Brain Res. , vol.555 , pp. 99-106
    • Vornov, J.J.1    Coyle, J.T.2
  • 82
    • 0030640779 scopus 로고    scopus 로고
    • A review of earlier clinical studies on neuro-protective agents and current approaches
    • Wahlgren N. G. (1997) A review of earlier clinical studies on neuro-protective agents and current approaches. Int. Rev. Neurobiol. 40, 337-363.
    • (1997) Int. Rev. Neurobiol. , vol.40 , pp. 337-363
    • Wahlgren, N.G.1
  • 83
    • 0032567740 scopus 로고    scopus 로고
    • Excitotoxic swelling occurs in oxygen and glucose deprived human cortical slices
    • Werth J. L., Park T. S., Silbergeld D. L. and Rothman S. M. (1998) Excitotoxic swelling occurs in oxygen and glucose deprived human cortical slices. Brain Res. 782, 248-254.
    • (1998) Brain Res. , vol.782 , pp. 248-254
    • Werth, J.L.1    Park, T.S.2    Silbergeld, D.L.3    Rothman, S.M.4
  • 84
    • 0021272555 scopus 로고
    • An in vitro model of ischemia: Metabolic and electrical alterations in the hippocampal slice
    • Whittingham T. S., Lust W. D. and Passonneau J. V. (1984) An in vitro model of ischemia: metabolic and electrical alterations in the hippocampal slice. J. Neurosci. 4, 793-802.
    • (1984) J. Neurosci. , vol.4 , pp. 793-802
    • Whittingham, T.S.1    Lust, W.D.2    Passonneau, J.V.3
  • 85
    • 0036711851 scopus 로고    scopus 로고
    • Bench to bedside: Brain edema and cerebral resus citation: The present and future
    • Xiao F. (2002) Bench to bedside: brain edema and cerebral resus citation: the present and future. Acad. Emerg. Med. 9, 933-946.
    • (2002) Acad. Emerg. Med. , vol.9 , pp. 933-946
    • Xiao, F.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.