Neuroprotection of γ-aminobutyric acid receptor agonists via enhancing neuronal nitric oxide synthase (Ser847) phosphorylation through increased neuronal nitric oxide synthase and PSD95 interaction and inhibited protein phosphatase activity in cerebral ischemia

Journal of Neuroscience Research

Volumn 86, Issue 13, 2008, Pages 2973-2983

  Zhou, Cui ^a   Li, Chong ^a   Yu, Hong Min ^a   Zhang, Fa ^a   Han, Dong ^a   Zhang, Guang Yi ^a  

^a XUZHOU MEDICAL UNIVERSITY   (China)

Author keywords

Brain ischemia; GABA receptor; Neuroprotection; NMDA receptor; nNOS; PSD95

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR STIMULATING AGENT; 4 AMINOBUTYRIC ACID B RECEPTOR STIMULATING AGENT; BACLOFEN; CALCINEURIN; DIZOCILPINE; MUSCIMOL; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NEURONAL NITRIC OXIDE SYNTHASE; PHOSPHOPROTEIN PHOSPHATASE 1; PHOSPHOPROTEIN PHOSPHATASE 2A; POSTSYNAPTIC DENSITY PROTEIN 95;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN ISCHEMIA; CEREBROVASCULAR ACCIDENT; CONTROLLED STUDY; DRUG PROTEIN BINDING; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; MALE; MOLECULAR MECHANICS; NERVE CELL NECROSIS; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; RAT; REPERFUSION INJURY;

ANIMALS; BACLOFEN; BLOTTING, WESTERN; BRAIN ISCHEMIA; DIZOCILPINE MALEATE; GABA AGONISTS; IMMUNOHISTOCHEMISTRY; IMMUNOPRECIPITATION; IN SITU NICK-END LABELING; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; MEMBRANE PROTEINS; MUSCIMOL; NEURONS; NEUROPROTECTIVE AGENTS; NITRIC OXIDE SYNTHASE TYPE I; PHOSPHOPROTEIN PHOSPHATASES; PHOSPHORYLATION; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, GABA;

EID: 57049115942     PISSN: 03604012     EISSN: 10974547     Source Type: Journal    
DOI: 10.1002/jnr.21728     Document Type: Article

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