A novel neuroprotective compound FR901459 with dual inhibition of calcineurin and cyclophilins

Acta Neurochirurgica, Supplementum

Volumn , Issue 96, 2006, Pages 157-162

  Uchino, H ^a,b   Morota, S ^c   Takahashi, T ^a   Ikeda, Y ^a   Kudo, Y ^c   Ishii, N ^a   Siesjo B K ^d   Shibasaki, F ^b  

^a TOKYO MEDICAL UNIVERSITY   (Japan)

^b TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE   (Japan)

^c TOKYO UNIVERSITY OF PHARMACY AND LIFE SCIENCES   (Japan)

^d NONE   (Sweden)

Author keywords

calcineurin; cyclophilin D; FR901495; Ischemic brain damage; mitochondrial permeability transition

Indexed keywords

CALCINEURIN; CARRIER PROTEIN; CYCLOPHILIN; CYCLOSPORIN; FR 901459; MITOCHONDRIAL PERMEABILITY TRANSITION PORE; NEUROPROTECTIVE AGENT;

ANIMAL; ARTICLE; BRAIN INJURY; BRAIN ISCHEMIA; DISEASE MODEL; DOSE RESPONSE; DRUG EFFECT; FOREBRAIN; INJURY; METABOLISM; RAT; TREATMENT OUTCOME; WISTAR RAT;

ANIMALS; BRAIN INJURIES; BRAIN ISCHEMIA; CALCINEURIN; CYCLOPHILINS; CYCLOSPORINE; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; MITOCHONDRIAL MEMBRANE TRANSPORT PROTEINS; NEUROPROTECTIVE AGENTS; PROSENCEPHALON; RATS; RATS, WISTAR; TREATMENT OUTCOME;

EID: 85052610420     PISSN: 00651419     EISSN: None     Source Type: Book Series    
DOI: 10.1007/3-211-30714-1_35     Document Type: Article

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