-
2
-
-
0024202693
-
Intracerebroventricular infusions of 3-OHB and insulin in a rat model of dietary obesity
-
Arase K., Fisler J.S., Shargill N.S., York D.A., and Bray G.A. Intracerebroventricular infusions of 3-OHB and insulin in a rat model of dietary obesity. Am. J. Physiol. 255 (1988) R974-R981
-
(1988)
Am. J. Physiol.
, vol.255
-
-
Arase, K.1
Fisler, J.S.2
Shargill, N.S.3
York, D.A.4
Bray, G.A.5
-
3
-
-
34547726345
-
Dissecting the molecular function of reggie/flotillin proteins
-
Babuke T., and Tikkanen R. Dissecting the molecular function of reggie/flotillin proteins. Eur. J. Cell Biol. 86 (2007) 525-532
-
(2007)
Eur. J. Cell Biol.
, vol.86
, pp. 525-532
-
-
Babuke, T.1
Tikkanen, R.2
-
4
-
-
4544366537
-
Effect of insulin on caveolin-enriched membrane domains in rat liver
-
Balbis A., Baquiran G., Mounier C., and Posner B.I. Effect of insulin on caveolin-enriched membrane domains in rat liver. J. Biol. Chem. 279 (2004) 39348-39357
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 39348-39357
-
-
Balbis, A.1
Baquiran, G.2
Mounier, C.3
Posner, B.I.4
-
5
-
-
37349104212
-
Type-1 cannabinoid receptors colocalize with caveolin-1 in neuronal cells
-
Bari M., Oddi S., De Simone C., Spagnolo P., Gasperi V., Battista N., Centonze D., and Maccarrone M. Type-1 cannabinoid receptors colocalize with caveolin-1 in neuronal cells. Neuropharmacology 54 (2008) 45-50
-
(2008)
Neuropharmacology
, vol.54
, pp. 45-50
-
-
Bari, M.1
Oddi, S.2
De Simone, C.3
Spagnolo, P.4
Gasperi, V.5
Battista, N.6
Centonze, D.7
Maccarrone, M.8
-
7
-
-
0031010267
-
Flotillin and epidermal surface antigen define a new family of caveolae-associated integral membrane proteins
-
Bickel P.E., Scherer P.E., Schnitzer J.E., Oh P., Lisanti M.P., and Lodish H.F. Flotillin and epidermal surface antigen define a new family of caveolae-associated integral membrane proteins. J. Biol. Chem. 272 (1997) 13793-13802
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 13793-13802
-
-
Bickel, P.E.1
Scherer, P.E.2
Schnitzer, J.E.3
Oh, P.4
Lisanti, M.P.5
Lodish, H.F.6
-
8
-
-
0030921159
-
Reduction of tyrosine kinase activity and protein tyrosine dephosphorylation by anoxic stimulation in vitro
-
Braunton J.L., Wong V., Wang W., Salter M.W., Roder J., Liu M., and Wang Y.T. Reduction of tyrosine kinase activity and protein tyrosine dephosphorylation by anoxic stimulation in vitro. Neuroscience 82 (1998) 161-170
-
(1998)
Neuroscience
, vol.82
, pp. 161-170
-
-
Braunton, J.L.1
Wong, V.2
Wang, W.3
Salter, M.W.4
Roder, J.5
Liu, M.6
Wang, Y.T.7
-
9
-
-
33845309656
-
Lipid rafts, detergent-resistant membranes, and raft targeting signals
-
Brown D.A. Lipid rafts, detergent-resistant membranes, and raft targeting signals. Physiology (Bethesda) 21 (2006) 430-439
-
(2006)
Physiology (Bethesda)
, vol.21
, pp. 430-439
-
-
Brown, D.A.1
-
10
-
-
0034703229
-
Role of brain insulin receptor in control of body weight and reproduction
-
Bruning J.C., Gautam D., Burks D.J., Gillette J., Schubert M., Orban P.C., Klein R., Krone W., Muller-Wieland D., and Kahn C.R. Role of brain insulin receptor in control of body weight and reproduction. Science 289 (2000) 2122-2125
-
(2000)
Science
, vol.289
, pp. 2122-2125
-
-
Bruning, J.C.1
Gautam, D.2
Burks, D.J.3
Gillette, J.4
Schubert, M.5
Orban, P.C.6
Klein, R.7
Krone, W.8
Muller-Wieland, D.9
Kahn, C.R.10
-
11
-
-
0022411646
-
Degradation of insulin receptors by hepatoma cells: insulin-induced down-regulation results from an increase in the rate of basal receptor degradation
-
Capeau J., Lascols O., Flaig-Staedel C., Blivet M.J., Beck J.P., and Picard J. Degradation of insulin receptors by hepatoma cells: insulin-induced down-regulation results from an increase in the rate of basal receptor degradation. Biochimie 67 (1985) 1133-1141
-
(1985)
Biochimie
, vol.67
, pp. 1133-1141
-
-
Capeau, J.1
Lascols, O.2
Flaig-Staedel, C.3
Blivet, M.J.4
Beck, J.P.5
Picard, J.6
-
12
-
-
0031806620
-
Inhibition of clathrin-mediated endocytosis selectively attenuates specific insulin receptor signal transduction pathways
-
Ceresa B.P., Kao A.W., Santeler S.R., and Pessin J.E. Inhibition of clathrin-mediated endocytosis selectively attenuates specific insulin receptor signal transduction pathways. Mol. Cell Biol. 18 (1998) 3862-3870
-
(1998)
Mol. Cell Biol.
, vol.18
, pp. 3862-3870
-
-
Ceresa, B.P.1
Kao, A.W.2
Santeler, S.R.3
Pessin, J.E.4
-
13
-
-
0036183603
-
Coordinated action of protein tyrosine phosphatases in insulin signal transduction
-
Cheng A., Dube N., Gu F., and Tremblay M.L. Coordinated action of protein tyrosine phosphatases in insulin signal transduction. Eur. J. Biochem. 269 (2002) 1050-1059
-
(2002)
Eur. J. Biochem.
, vol.269
, pp. 1050-1059
-
-
Cheng, A.1
Dube, N.2
Gu, F.3
Tremblay, M.L.4
-
14
-
-
15544374102
-
Reduced anorexic effects of insulin in obesity-prone rats fed a moderate-fat diet
-
Clegg D.J., Benoit S.C., Reed J.A., Woods S.C., Dunn-Meynell A., and Levin B.E. Reduced anorexic effects of insulin in obesity-prone rats fed a moderate-fat diet. Am. J. Physiol. Regul. Integr. Comp. Physiol. 288 (2005) R981-R986
-
(2005)
Am. J. Physiol. Regul. Integr. Comp. Physiol.
, vol.288
-
-
Clegg, D.J.1
Benoit, S.C.2
Reed, J.A.3
Woods, S.C.4
Dunn-Meynell, A.5
Levin, B.E.6
-
15
-
-
15244350991
-
Review of insulin and insulin-like growth factor expression, signaling, and malfunction in the central nervous system: relevance to Alzheimer's disease
-
de la Monte S.M., and Wands J.R. Review of insulin and insulin-like growth factor expression, signaling, and malfunction in the central nervous system: relevance to Alzheimer's disease. J. Alzheimer's Dis. 7 (2005) 45-61
-
(2005)
J. Alzheimer's Dis.
, vol.7
, pp. 45-61
-
-
de la Monte, S.M.1
Wands, J.R.2
-
16
-
-
24944438230
-
Consumption of a fat-rich diet activates a proinflammatory response and induces insulin resistance in the hypothalamus
-
De Souza C.T., Araujo E.P., Bordin S., Ashimine R., Zollner R.L., Boschero A.C., Saad M.J., and Velloso L.A. Consumption of a fat-rich diet activates a proinflammatory response and induces insulin resistance in the hypothalamus. Endocrinology 146 (2005) 4192-4199
-
(2005)
Endocrinology
, vol.146
, pp. 4192-4199
-
-
De Souza, C.T.1
Araujo, E.P.2
Bordin, S.3
Ashimine, R.4
Zollner, R.L.5
Boschero, A.C.6
Saad, M.J.7
Velloso, L.A.8
-
17
-
-
33645863768
-
Transcriptional regulation of metabolism
-
Desvergne B., Michalik L., and Wahli W. Transcriptional regulation of metabolism. Physiol. Rev. 86 (2006) 465-514
-
(2006)
Physiol. Rev.
, vol.86
, pp. 465-514
-
-
Desvergne, B.1
Michalik, L.2
Wahli, W.3
-
18
-
-
0032954778
-
Effects of free fatty acids on glucose transport and IRS-1-associated phosphatidylinositol 3-kinase activity
-
Dresner A., Laurent D., Marcucci M., Griffin M.E., Dufour S., Cline G.W., Slezak L.A., Andersen D.K., Hundal R.S., Rothman D.L., Petersen K.F., and Shulman G.I. Effects of free fatty acids on glucose transport and IRS-1-associated phosphatidylinositol 3-kinase activity. J. Clin. Invest. 103 (1999) 253-259
-
(1999)
J. Clin. Invest.
, vol.103
, pp. 253-259
-
-
Dresner, A.1
Laurent, D.2
Marcucci, M.3
Griffin, M.E.4
Dufour, S.5
Cline, G.W.6
Slezak, L.A.7
Andersen, D.K.8
Hundal, R.S.9
Rothman, D.L.10
Petersen, K.F.11
Shulman, G.I.12
-
20
-
-
0035936527
-
Pravastatin and the development of diabetes mellitus: evidence for a protective treatment effect in the West of Scotland Coronary Prevention Study
-
Freeman D.J., Norrie J., Sattar N., Neely R.D., Cobbe S.M., Ford I., Isles C., Lorimer A.R., Macfarlane P.W., McKillop J.H., Packard C.J., Shepherd J., and Gaw A. Pravastatin and the development of diabetes mellitus: evidence for a protective treatment effect in the West of Scotland Coronary Prevention Study. Circulation 103 (2001) 357-362
-
(2001)
Circulation
, vol.103
, pp. 357-362
-
-
Freeman, D.J.1
Norrie, J.2
Sattar, N.3
Neely, R.D.4
Cobbe, S.M.5
Ford, I.6
Isles, C.7
Lorimer, A.R.8
Macfarlane, P.W.9
McKillop, J.H.10
Packard, C.J.11
Shepherd, J.12
Gaw, A.13
-
21
-
-
33749033095
-
Rafts in oligodendrocytes: evidence and structure-function relationship
-
Gielen E., Baron W., Vandeven M., Steels P., Hoekstra D., and Ameloot M. Rafts in oligodendrocytes: evidence and structure-function relationship. Glia 54 (2006) 499-512
-
(2006)
Glia
, vol.54
, pp. 499-512
-
-
Gielen, E.1
Baron, W.2
Vandeven, M.3
Steels, P.4
Hoekstra, D.5
Ameloot, M.6
-
22
-
-
85047684646
-
Protein-tyrosine phosphatases: emerging targets for therapeutic intervention in type 2 diabetes and related states of insulin resistance
-
Goldstein B.J. Protein-tyrosine phosphatases: emerging targets for therapeutic intervention in type 2 diabetes and related states of insulin resistance. J. Clin. Endocrinol. Metab. 87 (2002) 2474-2480
-
(2002)
J. Clin. Endocrinol. Metab.
, vol.87
, pp. 2474-2480
-
-
Goldstein, B.J.1
-
23
-
-
0018090354
-
Insulin receptors are widely distributed in the central nervous system of the rat
-
Havrankova J., Roth J., and Brownstein M. Insulin receptors are widely distributed in the central nervous system of the rat. Nature 272 (1978) 827-829
-
(1978)
Nature
, vol.272
, pp. 827-829
-
-
Havrankova, J.1
Roth, J.2
Brownstein, M.3
-
24
-
-
0037996880
-
Lipid rafts in the maintenance of synapses, dendritic spines, and surface AMPA receptor stability
-
Hering H., Lin C.C., and Sheng M. Lipid rafts in the maintenance of synapses, dendritic spines, and surface AMPA receptor stability. J. Neurosci. 23 (2003) 3262-3271
-
(2003)
J. Neurosci.
, vol.23
, pp. 3262-3271
-
-
Hering, H.1
Lin, C.C.2
Sheng, M.3
-
26
-
-
43449107449
-
Regulation of AMPA receptor localization in lipid rafts
-
Hou Q., Huang Y., Amato S., Snyder S.H., Huganir R.L., and Man H.Y. Regulation of AMPA receptor localization in lipid rafts. Mol. Cell Neurosci. 38 (2008) 213-223
-
(2008)
Mol. Cell Neurosci.
, vol.38
, pp. 213-223
-
-
Hou, Q.1
Huang, Y.2
Amato, S.3
Snyder, S.H.4
Huganir, R.L.5
Man, H.Y.6
-
27
-
-
27744556268
-
Lipid microdomains and insulin resistance: is there a connection?
-
Ikonen E., and Vainio S. Lipid microdomains and insulin resistance: is there a connection?. Sci. STKE 2005 (2005) pe3
-
(2005)
Sci. STKE
, vol.2005
-
-
Ikonen, E.1
Vainio, S.2
-
28
-
-
33845903638
-
Altered hypothalamic leptin, insulin, and melanocortin binding associated with moderate-fat diet and predisposition to obesity
-
Irani B.G., Dunn-Meynell A.A., and Levin B.E. Altered hypothalamic leptin, insulin, and melanocortin binding associated with moderate-fat diet and predisposition to obesity. Endocrinology 148 (2007) 310-316
-
(2007)
Endocrinology
, vol.148
, pp. 310-316
-
-
Irani, B.G.1
Dunn-Meynell, A.A.2
Levin, B.E.3
-
29
-
-
2142710163
-
Altered lipid raft-associated signaling and ganglioside expression in T lymphocytes from patients with systemic lupus erythematosus
-
Jury E.C., Kabouridis P.S., Flores-Borja F., Mageed R.A., and Isenberg D.A. Altered lipid raft-associated signaling and ganglioside expression in T lymphocytes from patients with systemic lupus erythematosus. J. Clin. Invest. 113 (2004) 1176-1187
-
(2004)
J. Clin. Invest.
, vol.113
, pp. 1176-1187
-
-
Jury, E.C.1
Kabouridis, P.S.2
Flores-Borja, F.3
Mageed, R.A.4
Isenberg, D.A.5
-
30
-
-
13444251524
-
TNFalpha-induced insulin resistance in adipocytes as a membrane microdomain disorder: involvement of ganglioside GM3
-
Kabayama K., Sato T., Kitamura F., Uemura S., Kang B.W., Igarashi Y., and Inokuchi J. TNFalpha-induced insulin resistance in adipocytes as a membrane microdomain disorder: involvement of ganglioside GM3. Glycobiology 15 (2005) 21-29
-
(2005)
Glycobiology
, vol.15
, pp. 21-29
-
-
Kabayama, K.1
Sato, T.2
Kitamura, F.3
Uemura, S.4
Kang, B.W.5
Igarashi, Y.6
Inokuchi, J.7
-
31
-
-
35548958819
-
Regulation of D1 dopamine receptor trafficking and signaling by caveolin-1
-
Kong M.M., Hasbi A., Mattocks M., Fan T., O'Dowd B.F., and George S.R. Regulation of D1 dopamine receptor trafficking and signaling by caveolin-1. Mol. Pharmacol. 72 (2007) 1157-1170
-
(2007)
Mol. Pharmacol.
, vol.72
, pp. 1157-1170
-
-
Kong, M.M.1
Hasbi, A.2
Mattocks, M.3
Fan, T.4
O'Dowd, B.F.5
George, S.R.6
-
32
-
-
56249124005
-
Lipid rafts, cholesterol, and the brain
-
Korade Z., and Kenworthy A.K. Lipid rafts, cholesterol, and the brain. Neuropharmacology 55 (2008) 1265-1273
-
(2008)
Neuropharmacology
, vol.55
, pp. 1265-1273
-
-
Korade, Z.1
Kenworthy, A.K.2
-
33
-
-
36849086456
-
Statin modulates insulin signaling and insulin resistance in liver and muscle of rats fed a high-fat diet
-
Lalli C.A., Pauli J.R., Prada P.O., Cintra D.E., Ropelle E.R., Velloso L.A., and Saad M.J. Statin modulates insulin signaling and insulin resistance in liver and muscle of rats fed a high-fat diet. Metabolism 57 (2008) 57-65
-
(2008)
Metabolism
, vol.57
, pp. 57-65
-
-
Lalli, C.A.1
Pauli, J.R.2
Prada, P.O.3
Cintra, D.E.4
Ropelle, E.R.5
Velloso, L.A.6
Saad, M.J.7
-
34
-
-
0036479204
-
Caveolin-1 is a negative regulator of caveolae-mediated endocytosis to the endoplasmic reticulum
-
Le P.U., Guay G., Altschuler Y., and Nabi I.R. Caveolin-1 is a negative regulator of caveolae-mediated endocytosis to the endoplasmic reticulum. J. Biol. Chem. 277 (2002) 3371-3379
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 3371-3379
-
-
Le, P.U.1
Guay, G.2
Altschuler, Y.3
Nabi, I.R.4
-
35
-
-
28444493002
-
Factors promoting and ameliorating the development of obesity
-
Levin B.E. Factors promoting and ameliorating the development of obesity. Physiol. Behav. 86 (2005) 633-639
-
(2005)
Physiol. Behav.
, vol.86
, pp. 633-639
-
-
Levin, B.E.1
-
37
-
-
19644371019
-
Localization of receptors in lipid rafts can inhibit signal transduction
-
Lim K.I., and Yin J. Localization of receptors in lipid rafts can inhibit signal transduction. Biotechnol. Bioeng. 90 (2005) 694-702
-
(2005)
Biotechnol. Bioeng.
, vol.90
, pp. 694-702
-
-
Lim, K.I.1
Yin, J.2
-
38
-
-
0038673369
-
Ligand-dependent recruitment of the ErbB4 signaling complex into neuronal lipid rafts
-
Ma L., Huang Y.Z., Pitcher G.M., Valtschanoff J.G., Ma Y.H., Feng L.Y., Lu B., Xiong W.C., Salter M.W., Weinberg R.J., and Mei L. Ligand-dependent recruitment of the ErbB4 signaling complex into neuronal lipid rafts. J. Neurosci. 23 (2003) 3164-3175
-
(2003)
J. Neurosci.
, vol.23
, pp. 3164-3175
-
-
Ma, L.1
Huang, Y.Z.2
Pitcher, G.M.3
Valtschanoff, J.G.4
Ma, Y.H.5
Feng, L.Y.6
Lu, B.7
Xiong, W.C.8
Salter, M.W.9
Weinberg, R.J.10
Mei, L.11
-
39
-
-
0033681557
-
Regulation of AMPA receptor-mediated synaptic transmission by clathrin-dependent receptor internalization
-
Man H.Y., Lin J.W., Ju W.H., Ahmadian G., Liu L., Becker L.E., Sheng M., and Wang Y.T. Regulation of AMPA receptor-mediated synaptic transmission by clathrin-dependent receptor internalization. Neuron 25 (2000) 649-662
-
(2000)
Neuron
, vol.25
, pp. 649-662
-
-
Man, H.Y.1
Lin, J.W.2
Ju, W.H.3
Ahmadian, G.4
Liu, L.5
Becker, L.E.6
Sheng, M.7
Wang, Y.T.8
-
40
-
-
0036114024
-
Treatment with atorvastatin ameliorates hepatic very-low-density lipoprotein overproduction in an animal model of insulin resistance, the fructose-fed Syrian golden hamster: evidence that reduced hypertriglyceridemia is accompanied by improved hepatic insulin sensitivity
-
Mangaloglu L., Cheung R.C., Van Iderstine S.C., Taghibiglou C., Pontrelli L., and Adeli K. Treatment with atorvastatin ameliorates hepatic very-low-density lipoprotein overproduction in an animal model of insulin resistance, the fructose-fed Syrian golden hamster: evidence that reduced hypertriglyceridemia is accompanied by improved hepatic insulin sensitivity. Metabolism 51 (2002) 409-418
-
(2002)
Metabolism
, vol.51
, pp. 409-418
-
-
Mangaloglu, L.1
Cheung, R.C.2
Van Iderstine, S.C.3
Taghibiglou, C.4
Pontrelli, L.5
Adeli, K.6
-
41
-
-
33751268368
-
Protein serine/threonine phosphatases in neuronal plasticity and disorders of learning and memory
-
Mansuy I.M., and Shenolikar S. Protein serine/threonine phosphatases in neuronal plasticity and disorders of learning and memory. Trends Neurosci. 29 (2006) 679-686
-
(2006)
Trends Neurosci.
, vol.29
, pp. 679-686
-
-
Mansuy, I.M.1
Shenolikar, S.2
-
42
-
-
0029365123
-
Effects of obesity and gender on insulin receptor expression in liver of SHHF/Mcc-FAcp rats
-
Meier D.A., Hennes M.M., McCune S.A., and Kissebah A.H. Effects of obesity and gender on insulin receptor expression in liver of SHHF/Mcc-FAcp rats. Obes. Res. 3 (1995) 465-470
-
(1995)
Obes. Res.
, vol.3
, pp. 465-470
-
-
Meier, D.A.1
Hennes, M.M.2
McCune, S.A.3
Kissebah, A.H.4
-
43
-
-
33847706096
-
Lipid rafts in health and disease
-
Michel V., and Bakovic M. Lipid rafts in health and disease. Biol. Cell 99 (2007) 129-140
-
(2007)
Biol. Cell
, vol.99
, pp. 129-140
-
-
Michel, V.1
Bakovic, M.2
-
44
-
-
20744444237
-
A biochemical and functional characterization of diet-induced brain insulin resistance
-
Mielke J.G., Taghibiglou C., Liu L., Zhang Y., Jia Z., Adeli K., and Wang Y.T. A biochemical and functional characterization of diet-induced brain insulin resistance. J. Neurochem. 93 (2005) 1568-1578
-
(2005)
J. Neurochem.
, vol.93
, pp. 1568-1578
-
-
Mielke, J.G.1
Taghibiglou, C.2
Liu, L.3
Zhang, Y.4
Jia, Z.5
Adeli, K.6
Wang, Y.T.7
-
45
-
-
33750495607
-
Endogenous insulin signaling protects cultured neurons from oxygen-glucose deprivation-induced cell death
-
Mielke J.G., Taghibiglou C., and Wang Y.T. Endogenous insulin signaling protects cultured neurons from oxygen-glucose deprivation-induced cell death. Neuroscience 143 (2006) 165-173
-
(2006)
Neuroscience
, vol.143
, pp. 165-173
-
-
Mielke, J.G.1
Taghibiglou, C.2
Wang, Y.T.3
-
46
-
-
9244219587
-
Region-specific leptin resistance within the hypothalamus of diet-induced obese mice
-
Munzberg H., Flier J.S., and Bjorbaek C. Region-specific leptin resistance within the hypothalamus of diet-induced obese mice. Endocrinology 145 (2004) 4880-4889
-
(2004)
Endocrinology
, vol.145
, pp. 4880-4889
-
-
Munzberg, H.1
Flier, J.S.2
Bjorbaek, C.3
-
47
-
-
33646865041
-
Insulin resistance and improvements in signal transduction
-
Musi N., and Goodyear L.J. Insulin resistance and improvements in signal transduction. Endocrine 29 (2006) 73-80
-
(2006)
Endocrine
, vol.29
, pp. 73-80
-
-
Musi, N.1
Goodyear, L.J.2
-
48
-
-
40949136571
-
Effect of rosuvastatin on insulin sensitivity in an animal model of insulin resistance: evidence for statin-induced hepatic insulin sensitization
-
Naples M., Federico L.M., Xu E., Nelken J., and Adeli K. Effect of rosuvastatin on insulin sensitivity in an animal model of insulin resistance: evidence for statin-induced hepatic insulin sensitization. Atherosclerosis 198 (2008) 94-103
-
(2008)
Atherosclerosis
, vol.198
, pp. 94-103
-
-
Naples, M.1
Federico, L.M.2
Xu, E.3
Nelken, J.4
Adeli, K.5
-
49
-
-
0034720181
-
Absence of TrkB and insulin receptor beta in the triton insoluble low-density fraction (raft)
-
Ohira K., Maekawa S., and Hayashi M. Absence of TrkB and insulin receptor beta in the triton insoluble low-density fraction (raft). Neuroreport 11 (2000) 1307-1311
-
(2000)
Neuroreport
, vol.11
, pp. 1307-1311
-
-
Ohira, K.1
Maekawa, S.2
Hayashi, M.3
-
50
-
-
1542723726
-
Insulin resistance is associated with increased cholesterol synthesis and decreased cholesterol absorption in normoglycemic men
-
Pihlajamaki J., Gylling H., Miettinen T.A., and Laakso M. Insulin resistance is associated with increased cholesterol synthesis and decreased cholesterol absorption in normoglycemic men. J. Lipid Res. 45 (2004) 507-512
-
(2004)
J. Lipid Res.
, vol.45
, pp. 507-512
-
-
Pihlajamaki, J.1
Gylling, H.2
Miettinen, T.A.3
Laakso, M.4
-
51
-
-
0037072273
-
Cholesterol levels modulate EGF receptor-mediated signaling by altering receptor function and trafficking
-
Pike L.J., and Casey L. Cholesterol levels modulate EGF receptor-mediated signaling by altering receptor function and trafficking. Biochemistry 41 (2002) 10315-10322
-
(2002)
Biochemistry
, vol.41
, pp. 10315-10322
-
-
Pike, L.J.1
Casey, L.2
-
54
-
-
67650650441
-
Hypothalamic proinflammatory lipid accumulation, inflammation, and insulin resistance in rats fed a high-fat diet
-
Posey K., Clegg D.J., Printz R.L., Byun J., Morton G.J., Vivekanandan-Giri A., Pennathur S., Baskin D.G., Heinecke J.W., Woods S.C., Schwartz M.W., and Niswender K.D. Hypothalamic proinflammatory lipid accumulation, inflammation, and insulin resistance in rats fed a high-fat diet. Am. J. Physiol. Endocrinol. Metab. (2008)
-
(2008)
Am. J. Physiol. Endocrinol. Metab.
-
-
Posey, K.1
Clegg, D.J.2
Printz, R.L.3
Byun, J.4
Morton, G.J.5
Vivekanandan-Giri, A.6
Pennathur, S.7
Baskin, D.G.8
Heinecke, J.W.9
Woods, S.C.10
Schwartz, M.W.11
Niswender, K.D.12
-
55
-
-
0037166323
-
Sequestration of epidermal growth factor receptors in non-caveolar lipid rafts inhibits ligand binding
-
Roepstorff K., Thomsen P., Sandvig K., and van Deurs B. Sequestration of epidermal growth factor receptors in non-caveolar lipid rafts inhibits ligand binding. J. Biol. Chem. 277 (2002) 18954-18960
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 18954-18960
-
-
Roepstorff, K.1
Thomsen, P.2
Sandvig, K.3
van Deurs, B.4
-
56
-
-
0242268533
-
Insulin signaling in microdomains of the plasma membrane
-
Saltiel A.R., and Pessin J.E. Insulin signaling in microdomains of the plasma membrane. Traffic 4 (2003) 711-716
-
(2003)
Traffic
, vol.4
, pp. 711-716
-
-
Saltiel, A.R.1
Pessin, J.E.2
-
57
-
-
12144290448
-
Role for neuronal insulin resistance in neurodegenerative diseases
-
Schubert M., Gautam D., Surjo D., Ueki K., Baudler S., Schubert D., Kondo T., Alber J., Galldiks N., Kustermann E., Arndt S., Jacobs A.H., Krone W., Kahn C.R., and Bruning J.C. Role for neuronal insulin resistance in neurodegenerative diseases. Proc. Natl. Acad. Sci. U.S.A. 101 (2004) 3100-3105
-
(2004)
Proc. Natl. Acad. Sci. U.S.A.
, vol.101
, pp. 3100-3105
-
-
Schubert, M.1
Gautam, D.2
Surjo, D.3
Ueki, K.4
Baudler, S.5
Schubert, D.6
Kondo, T.7
Alber, J.8
Galldiks, N.9
Kustermann, E.10
Arndt, S.11
Jacobs, A.H.12
Krone, W.13
Kahn, C.R.14
Bruning, J.C.15
-
58
-
-
33745828640
-
Insulin resistance and atherosclerosis
-
Semenkovich C.F. Insulin resistance and atherosclerosis. J. Clin. Invest. 116 (2006) 1813-1822
-
(2006)
J. Clin. Invest.
, vol.116
, pp. 1813-1822
-
-
Semenkovich, C.F.1
-
59
-
-
0033927667
-
Cellular mechanisms of insulin resistance
-
Shulman G.I. Cellular mechanisms of insulin resistance. J. Clin. Invest. 106 (2000) 171-176
-
(2000)
J. Clin. Invest.
, vol.106
, pp. 171-176
-
-
Shulman, G.I.1
-
60
-
-
0030949124
-
Functional rafts in cell membranes
-
Simons K., and Ikonen E. Functional rafts in cell membranes. Nature 387 (1997) 569-572
-
(1997)
Nature
, vol.387
, pp. 569-572
-
-
Simons, K.1
Ikonen, E.2
-
61
-
-
15244351255
-
Impaired insulin and insulin-like growth factor expression and signaling mechanisms in Alzheimer's disease - is this type 3 diabetes?
-
Steen E., Terry B.M., Rivera E.J., Cannon J.L., Neely T.R., Tavares R., Xu X.J., Wands J.R., and de la Monte S.M. Impaired insulin and insulin-like growth factor expression and signaling mechanisms in Alzheimer's disease - is this type 3 diabetes?. J. Alzheimer's Dis. 7 (2005) 63-80
-
(2005)
J. Alzheimer's Dis.
, vol.7
, pp. 63-80
-
-
Steen, E.1
Terry, B.M.2
Rivera, E.J.3
Cannon, J.L.4
Neely, T.R.5
Tavares, R.6
Xu, X.J.7
Wands, J.R.8
de la Monte, S.M.9
-
62
-
-
0034708682
-
Mechanisms of hepatic very low density lipoprotein overproduction in insulin resistance. Evidence for enhanced lipoprotein assembly, reduced intracellular ApoB degradation, and increased microsomal triglyceride transfer protein in a fructose-fed hamster model
-
Taghibiglou C., Carpentier A., Van Iderstine S.C., Chen B., Rudy D., Aiton A., Lewis G.F., and Adeli K. Mechanisms of hepatic very low density lipoprotein overproduction in insulin resistance. Evidence for enhanced lipoprotein assembly, reduced intracellular ApoB degradation, and increased microsomal triglyceride transfer protein in a fructose-fed hamster model. J. Biol. Chem. 275 (2000) 8416-8425
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 8416-8425
-
-
Taghibiglou, C.1
Carpentier, A.2
Van Iderstine, S.C.3
Chen, B.4
Rudy, D.5
Aiton, A.6
Lewis, G.F.7
Adeli, K.8
-
63
-
-
0037016727
-
Hepatic very low density lipoprotein-ApoB overproduction is associated with attenuated hepatic insulin signaling and overexpression of protein-tyrosine phosphatase 1B in a fructose-fed hamster model of insulin resistance
-
Taghibiglou C., Rashid-Kolvear F., Van Iderstine S.C., Le-Tien H., Fantus I.G., Lewis G.F., and Adeli K. Hepatic very low density lipoprotein-ApoB overproduction is associated with attenuated hepatic insulin signaling and overexpression of protein-tyrosine phosphatase 1B in a fructose-fed hamster model of insulin resistance. J. Biol. Chem. 277 (2002) 793-803
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 793-803
-
-
Taghibiglou, C.1
Rashid-Kolvear, F.2
Van Iderstine, S.C.3
Le-Tien, H.4
Fantus, I.G.5
Lewis, G.F.6
Adeli, K.7
-
64
-
-
0020402102
-
Decreased insulin binding in cultured lymphocytes from two patients with extreme insulin resistance
-
Taylor S.I., Samuels B., Roth J., Kasuga M., Hedo J.A., Gorden P., Brasel D.E., Pokora T., and Engel R.R. Decreased insulin binding in cultured lymphocytes from two patients with extreme insulin resistance. J. Clin. Endocrinol. Metab. 54 (1982) 919-930
-
(1982)
J. Clin. Endocrinol. Metab.
, vol.54
, pp. 919-930
-
-
Taylor, S.I.1
Samuels, B.2
Roth, J.3
Kasuga, M.4
Hedo, J.A.5
Gorden, P.6
Brasel, D.E.7
Pokora, T.8
Engel, R.R.9
-
65
-
-
33748068817
-
The insulin/PI 3-kinase pathway regulates salt chemotaxis learning in Caenorhabditis elegans
-
Tomioka M., Adachi T., Suzuki H., Kunitomo H., Schafer W.R., and Iino Y. The insulin/PI 3-kinase pathway regulates salt chemotaxis learning in Caenorhabditis elegans. Neuron 51 (2006) 613-625
-
(2006)
Neuron
, vol.51
, pp. 613-625
-
-
Tomioka, M.1
Adachi, T.2
Suzuki, H.3
Kunitomo, H.4
Schafer, W.R.5
Iino, Y.6
-
66
-
-
33750299450
-
Protein tyrosine phosphatases: from genes, to function, to disease
-
Tonks N.K. Protein tyrosine phosphatases: from genes, to function, to disease. Nat. Rev. Mol. Cell Biol. 7 (2006) 833-846
-
(2006)
Nat. Rev. Mol. Cell Biol.
, vol.7
, pp. 833-846
-
-
Tonks, N.K.1
-
68
-
-
0347993701
-
Isoform-specific insulin receptor signaling involves different plasma membrane domains
-
Uhles S., Moede T., Leibiger B., Berggren P.O., and Leibiger I.B. Isoform-specific insulin receptor signaling involves different plasma membrane domains. J. Cell Biol. 163 (2003) 1327-1337
-
(2003)
J. Cell Biol.
, vol.163
, pp. 1327-1337
-
-
Uhles, S.1
Moede, T.2
Leibiger, B.3
Berggren, P.O.4
Leibiger, I.B.5
-
69
-
-
0036182137
-
Lipotoxic diseases
-
Unger R.H. Lipotoxic diseases. Annu. Rev. Med. 53 (2002) 319-336
-
(2002)
Annu. Rev. Med.
, vol.53
, pp. 319-336
-
-
Unger, R.H.1
-
70
-
-
27744533916
-
Defective insulin receptor activation and altered lipid rafts in Niemann-Pick type C disease hepatocytes
-
Vainio S., Bykov I., Hermansson M., Jokitalo E., Somerharju P., and Ikonen E. Defective insulin receptor activation and altered lipid rafts in Niemann-Pick type C disease hepatocytes. Biochem. J. 391 (2005) 465-472
-
(2005)
Biochem. J.
, vol.391
, pp. 465-472
-
-
Vainio, S.1
Bykov, I.2
Hermansson, M.3
Jokitalo, E.4
Somerharju, P.5
Ikonen, E.6
-
71
-
-
0036166283
-
Dynamic association of human insulin receptor with lipid rafts in cells lacking caveolae
-
Vainio S., Heino S., Mansson J.E., Fredman P., Kuismanen E., Vaarala O., and Ikonen E. Dynamic association of human insulin receptor with lipid rafts in cells lacking caveolae. EMBO Rep. 3 (2002) 95-100
-
(2002)
EMBO Rep.
, vol.3
, pp. 95-100
-
-
Vainio, S.1
Heino, S.2
Mansson, J.E.3
Fredman, P.4
Kuismanen, E.5
Vaarala, O.6
Ikonen, E.7
-
72
-
-
33748295795
-
Insulin signaling in the central nervous system: learning to survive
-
van der Heide L.P., Ramakers G.M., and Smidt M.P. Insulin signaling in the central nervous system: learning to survive. Prog. Neurobiol. 79 (2006) 205-221
-
(2006)
Prog. Neurobiol.
, vol.79
, pp. 205-221
-
-
van der Heide, L.P.1
Ramakers, G.M.2
Smidt, M.P.3
-
73
-
-
27344446853
-
New twist on neuronal insulin receptor signaling in health, disease, and therapeutics
-
Wada A., Yokoo H., Yanagita T., and Kobayashi H. New twist on neuronal insulin receptor signaling in health, disease, and therapeutics. J. Pharmacol. Sci. 99 (2005) 128-143
-
(2005)
J. Pharmacol. Sci.
, vol.99
, pp. 128-143
-
-
Wada, A.1
Yokoo, H.2
Yanagita, T.3
Kobayashi, H.4
-
74
-
-
0030800192
-
Recruitment of functional GABA(A) receptors to postsynaptic domains by insulin
-
Wan Q., Xiong Z.G., Man H.Y., Ackerley C.A., Braunton J., Lu W.Y., Becker L.E., MacDonald J.F., and Wang Y.T. Recruitment of functional GABA(A) receptors to postsynaptic domains by insulin. Nature 388 (1997) 686-690
-
(1997)
Nature
, vol.388
, pp. 686-690
-
-
Wan, Q.1
Xiong, Z.G.2
Man, H.Y.3
Ackerley, C.A.4
Braunton, J.5
Lu, W.Y.6
Becker, L.E.7
MacDonald, J.F.8
Wang, Y.T.9
-
75
-
-
0037523369
-
Control of synaptic strength, a novel function of Akt
-
Wang Q., Liu L., Pei L., Ju W., Ahmadian G., Lu J., Wang Y., Liu F., and Wang Y.T. Control of synaptic strength, a novel function of Akt. Neuron 38 (2003) 915-928
-
(2003)
Neuron
, vol.38
, pp. 915-928
-
-
Wang, Q.1
Liu, L.2
Pei, L.3
Ju, W.4
Ahmadian, G.5
Lu, J.6
Wang, Y.7
Liu, F.8
Wang, Y.T.9
-
76
-
-
0033713293
-
Expression of cerebellar long-term depression requires postsynaptic clathrin-mediated endocytosis
-
Wang Y.T., and Linden D.J. Expression of cerebellar long-term depression requires postsynaptic clathrin-mediated endocytosis. Neuron 25 (2000) 635-647
-
(2000)
Neuron
, vol.25
, pp. 635-647
-
-
Wang, Y.T.1
Linden, D.J.2
-
77
-
-
33745794668
-
Signalling mechanisms linking hepatic glucose and lipid metabolism
-
Weickert M.O., and Pfeiffer A.F. Signalling mechanisms linking hepatic glucose and lipid metabolism. Diabetologia 49 (2006) 1732-1741
-
(2006)
Diabetologia
, vol.49
, pp. 1732-1741
-
-
Weickert, M.O.1
Pfeiffer, A.F.2
-
78
-
-
33750217236
-
Lipotoxicity
-
Weinberg J.M. Lipotoxicity. Kidney Int. 70 (2006) 1560-1566
-
(2006)
Kidney Int.
, vol.70
, pp. 1560-1566
-
-
Weinberg, J.M.1
-
79
-
-
0036710280
-
IRS proteins and the common path to diabetes
-
White M.F. IRS proteins and the common path to diabetes. Am. J. Physiol. Endocrinol. Metab. 283 (2002) E413-E422
-
(2002)
Am. J. Physiol. Endocrinol. Metab.
, vol.283
-
-
White, M.F.1
-
81
-
-
30044442657
-
Atorvastatin induces insulin sensitization in Zucker lean and fatty rats
-
Wong V., Stavar L., Szeto L., Uffelman K., Wang C.H., Fantus I.G., and Lewis G.F. Atorvastatin induces insulin sensitization in Zucker lean and fatty rats. Atherosclerosis 184 (2006) 348-355
-
(2006)
Atherosclerosis
, vol.184
, pp. 348-355
-
-
Wong, V.1
Stavar, L.2
Szeto, L.3
Uffelman, K.4
Wang, C.H.5
Fantus, I.G.6
Lewis, G.F.7
-
82
-
-
0031034679
-
Tyrosine kinase receptors concentrated in caveolae-like domains from neuronal plasma membrane
-
Wu C., Butz S., Ying Y., and Anderson R.G. Tyrosine kinase receptors concentrated in caveolae-like domains from neuronal plasma membrane. J. Biol. Chem. 272 (1997) 3554-3559
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 3554-3559
-
-
Wu, C.1
Butz, S.2
Ying, Y.3
Anderson, R.G.4
-
83
-
-
0037184925
-
Mechanism by which fatty acids inhibit insulin activation of insulin receptor substrate-1 (IRS-1)-associated phosphatidylinositol 3-kinase activity in muscle
-
Yu C., Chen Y., Cline G.W., Zhang D., Zong H., Wang Y., Bergeron R., Kim J.K., Cushman S.W., Cooney G.J., Atcheson B., White M.F., Kraegen E.W., and Shulman G.I. Mechanism by which fatty acids inhibit insulin activation of insulin receptor substrate-1 (IRS-1)-associated phosphatidylinositol 3-kinase activity in muscle. J. Biol. Chem. 277 (2002) 50230-50236
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 50230-50236
-
-
Yu, C.1
Chen, Y.2
Cline, G.W.3
Zhang, D.4
Zong, H.5
Wang, Y.6
Bergeron, R.7
Kim, J.K.8
Cushman, S.W.9
Cooney, G.J.10
Atcheson, B.11
White, M.F.12
Kraegen, E.W.13
Shulman, G.I.14
-
84
-
-
52949096557
-
Hypothalamic IKKbeta/NF-kappaB and ER stress link overnutrition to energy imbalance and obesity
-
Zhang X., Zhang G., Zhang H., Karin M., Bai H., and Cai D. Hypothalamic IKKbeta/NF-kappaB and ER stress link overnutrition to energy imbalance and obesity. Cell 135 (2008) 61-73
-
(2008)
Cell
, vol.135
, pp. 61-73
-
-
Zhang, X.1
Zhang, G.2
Zhang, H.3
Karin, M.4
Bai, H.5
Cai, D.6
-
85
-
-
1242272929
-
PTEN inhibits cell proliferation and induces apoptosis by downregulating cell surface IGF-IR expression in prostate cancer cells
-
Zhao H., Dupont J., Yakar S., Karas M., and LeRoith D. PTEN inhibits cell proliferation and induces apoptosis by downregulating cell surface IGF-IR expression in prostate cancer cells. Oncogene 23 (2004) 786-794
-
(2004)
Oncogene
, vol.23
, pp. 786-794
-
-
Zhao, H.1
Dupont, J.2
Yakar, S.3
Karas, M.4
LeRoith, D.5
-
86
-
-
1842633872
-
Insulin and the insulin receptor in experimental models of learning and memory
-
Zhao W.Q., Chen H., Quon M.J., and Alkon D.L. Insulin and the insulin receptor in experimental models of learning and memory. Eur. J. Pharmacol. 490 (2004) 71-81
-
(2004)
Eur. J. Pharmacol.
, vol.490
, pp. 71-81
-
-
Zhao, W.Q.1
Chen, H.2
Quon, M.J.3
Alkon, D.L.4
-
87
-
-
38049110692
-
Amyloid beta oligomers induce impairment of neuronal insulin receptors
-
Zhao W.Q., De Felice F.G., Fernandez S., Chen H., Lambert M.P., Quon M.J., Krafft G.A., and Klein W.L. Amyloid beta oligomers induce impairment of neuronal insulin receptors. Faseb J. 22 (2008) 246-260
-
(2008)
Faseb J.
, vol.22
, pp. 246-260
-
-
Zhao, W.Q.1
De Felice, F.G.2
Fernandez, S.3
Chen, H.4
Lambert, M.P.5
Quon, M.J.6
Krafft, G.A.7
Klein, W.L.8
-
88
-
-
33646911084
-
Lipid rafts serve as a signaling platform for nicotinic acetylcholine receptor clustering
-
Zhu D., Xiong W.C., and Mei L. Lipid rafts serve as a signaling platform for nicotinic acetylcholine receptor clustering. J. Neurosci. 26 (2006) 4841-4851
-
(2006)
J. Neurosci.
, vol.26
, pp. 4841-4851
-
-
Zhu, D.1
Xiong, W.C.2
Mei, L.3
|