메뉴 건너뛰기




Volumn 26, Issue 18, 2006, Pages 4841-4851

Lipid rafts serve as a signaling platform for nicotinic acetylcholine receptor clustering

Author keywords

Agrin; Lipid rafts; muSK; Neuromuscular junction; Nicotinic acetylcholine receptors; Rapsyn

Indexed keywords

AGRIN; MUSCLE SPECIFIC RECEPTOR TYROSINE KINASE; NICOTINIC RECEPTOR; RAPSYN; TYROSINE KINASE RECEPTOR; UNCLASSIFIED DRUG; 2 DECANOYLAMINO 3 MORPHOLINO 1 PHENYL 1 PROPANOL; BUNGAROTOXIN; CAVEOLIN 3; CHOLERA TOXIN; ENZYME INHIBITOR; MAST CELL DEGRANULATING PEPTIDE; MONOUNSATURATED FATTY ACID; MORPHOLINE DERIVATIVE; MUSCLE PROTEIN; MUSK; NEU DIFFERENTIATION FACTOR; PEPTIDE; PERIPHERAL MEMBRANE PROTEIN 43K; SYNAPTOPHYSIN;

EID: 33646911084     PISSN: 02706474     EISSN: 02706474     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.2807-05.2006     Document Type: Article
Times cited : (122)

References (50)
  • 1
    • 0029155684 scopus 로고
    • Rapsyn may function as a link between the acetylcholine receptor and the agrin-binding dystrophin-associated glycoprotein complex
    • Apel ED, Roberds SL, Campbell KP, Merlie JP (1995) Rapsyn may function as a link between the acetylcholine receptor and the agrin-binding dystrophin-associated glycoprotein complex. Neuron 15:115-126.
    • (1995) Neuron , vol.15 , pp. 115-126
    • Apel, E.D.1    Roberds, S.L.2    Campbell, K.P.3    Merlie, J.P.4
  • 2
    • 0030940161 scopus 로고    scopus 로고
    • Rapsyn is required for MuSK signaling and recruits synaptic components to a MuSK-containing scaffold
    • Apel ED, Glass DJ, Moscoso LM, Yancopoulos GD, Sanes JR (1997) Rapsyn is required for MuSK signaling and recruits synaptic components to a MuSK-containing scaffold. Neuron 18:623-635.
    • (1997) Neuron , vol.18 , pp. 623-635
    • Apel, E.D.1    Glass, D.J.2    Moscoso, L.M.3    Yancopoulos, G.D.4    Sanes, J.R.5
  • 3
    • 0033552651 scopus 로고    scopus 로고
    • How does the plasma membrane participate in cellular signaling by receptors for immunoglobulin E?
    • Baird B, Sheets ED, Holowka D (1999) How does the plasma membrane participate in cellular signaling by receptors for immunoglobulin E? Biophys Chem 82:109-119.
    • (1999) Biophys Chem , vol.82 , pp. 109-119
    • Baird, B.1    Sheets, E.D.2    Holowka, D.3
  • 4
    • 9644294471 scopus 로고    scopus 로고
    • Structural basis for lipid modulation of nicotinic acetylcholine receptor function
    • Barrantes FJ (2004) Structural basis for lipid modulation of nicotinic acetylcholine receptor function. Brain Res Brain Res Rev 47:71-95.
    • (2004) Brain Res Brain Res Rev , vol.47 , pp. 71-95
    • Barrantes, F.J.1
  • 5
    • 0035178823 scopus 로고    scopus 로고
    • The gamma-aminobutyric acid receptor B, but not the metabotropic glutamate receptor type-1, associates with lipid rafts in the rat cerebellum
    • Becher A, White JH, McIlhinney RA (2001) The gamma-aminobutyric acid receptor B, but not the metabotropic glutamate receptor type-1, associates with lipid rafts in the rat cerebellum. J Neurochem 79:787-795.
    • (2001) J Neurochem , vol.79 , pp. 787-795
    • Becher, A.1    White, J.H.2    McIlhinney, R.A.3
  • 6
    • 0023096244 scopus 로고
    • The relationship of the postsynaptic 43K protein to acetylcholine receptors in receptor clusters isolated from cultured rat myotubes
    • Bloch RJ, Froehner SC (1987) The relationship of the postsynaptic 43K protein to acetylcholine receptors in receptor clusters isolated from cultured rat myotubes. J Cell Biol 104:645-654.
    • (1987) J Cell Biol , vol.104 , pp. 645-654
    • Bloch, R.J.1    Froehner, S.C.2
  • 7
    • 0035795420 scopus 로고    scopus 로고
    • Agrin-induced phosphorylation of the acetylcholine receptor regulates cytoskeletal anchoring and clustering
    • Borges LS, Ferns M (2001) Agrin-induced phosphorylation of the acetylcholine receptor regulates cytoskeletal anchoring and clustering. J Cell Biol 153:1-12.
    • (2001) J Cell Biol , vol.153 , pp. 1-12
    • Borges, L.S.1    Ferns, M.2
  • 8
    • 0032421354 scopus 로고    scopus 로고
    • Functions of lipid rafts in biological membranes
    • Brown DA, London E (1998) Functions of lipid rafts in biological membranes. Annu Rev Cell Dev Biol 14:111-136.
    • (1998) Annu Rev Cell Dev Biol , vol.14 , pp. 111-136
    • Brown, D.A.1    London, E.2
  • 9
    • 0035862961 scopus 로고    scopus 로고
    • Membrane lipid rafts are necessary for the maintenance of the (α)7 nicotinic acetylcholine receptor in somatic spines of ciliary neurons
    • Bruses JL, Chauvet N, Rutishauser U (2001) Membrane lipid rafts are necessary for the maintenance of the (α)7 nicotinic acetylcholine receptor in somatic spines of ciliary neurons. J Neurosci 21:504-512.
    • (2001) J Neurosci , vol.21 , pp. 504-512
    • Bruses, J.L.1    Chauvet, N.2    Rutishauser, U.3
  • 10
    • 0032695211 scopus 로고    scopus 로고
    • Uptake and intracellular transport of acidic fibroblast growth factor: Evidence for free and cytoskeleton-anchored fibroblast growth factor receptors
    • Citores L, Wesche J, Kolpakova E, Olsnes S (1999) Uptake and intracellular transport of acidic fibroblast growth factor: evidence for free and cytoskeleton-anchored fibroblast growth factor receptors. Mol Biol Cell 10:3835-3848.
    • (1999) Mol Biol Cell , vol.10 , pp. 3835-3848
    • Citores, L.1    Wesche, J.2    Kolpakova, E.3    Olsnes, S.4
  • 12
    • 0242457445 scopus 로고    scopus 로고
    • Characterization of membrane rafts isolated from rat sertoli cell cultures: Caveolin and flotillin-1 content
    • Evans WE, Coyer RL, Sandusky MF, Van Fleet MJ, Moore JG, Nyquist SE (2003) Characterization of membrane rafts isolated from rat sertoli cell cultures: caveolin and flotillin-1 content. J Androl 24:812-821.
    • (2003) J Androl , vol.24 , pp. 812-821
    • Evans, W.E.1    Coyer, R.L.2    Sandusky, M.F.3    Van Fleet, M.J.4    Moore, J.G.5    Nyquist, S.E.6
  • 13
    • 0027517961 scopus 로고
    • The ability of agrin to cluster AChRs depends on alternative splicing and on cell surface proteoglycans
    • Ferns MJ, Campanelli JT, Hoch W, Scheller RH, Hall Z (1993) The ability of agrin to cluster AChRs depends on alternative splicing and on cell surface proteoglycans. Neuron 11:491-502.
    • (1993) Neuron , vol.11 , pp. 491-502
    • Ferns, M.J.1    Campanelli, J.T.2    Hoch, W.3    Scheller, R.H.4    Hall, Z.5
  • 14
    • 0029928633 scopus 로고    scopus 로고
    • Agrin-induced acetylcholine receptor clustering in mammalian muscle requires tyrosine phosphorylation
    • Ferns M, Deiner M, Hall Z (1996) Agrin-induced acetylcholine receptor clustering in mammalian muscle requires tyrosine phosphorylation. J Cell Biol 132:937-944.
    • (1996) J Cell Biol , vol.132 , pp. 937-944
    • Ferns, M.1    Deiner, M.2    Hall, Z.3
  • 15
    • 0038392756 scopus 로고    scopus 로고
    • Postsynaptic requirement for Abl kinases in assembly of the neuromuscular junction
    • Finn AJ, Feng G, Pendergast AM (2003) Postsynaptic requirement for Abl kinases in assembly of the neuromuscular junction. Nat Neurosci 6:717-723.
    • (2003) Nat Neurosci , vol.6 , pp. 717-723
    • Finn, A.J.1    Feng, G.2    Pendergast, A.M.3
  • 16
    • 0023737805 scopus 로고
    • Identification of the mouse muscle 43,000-dalton acetylcholine receptor-associated protein (RAPsyn) by cDNA cloning
    • Frail DE, McLaughlin LL, Mudd J, Merlie JP (1988) Identification of the mouse muscle 43,000-dalton acetylcholine receptor-associated protein (RAPsyn) by cDNA cloning. J Biol Chem 263:15602-15607.
    • (1988) J Biol Chem , vol.263 , pp. 15602-15607
    • Frail, D.E.1    McLaughlin, L.L.2    Mudd, J.3    Merlie, J.P.4
  • 17
    • 0033179225 scopus 로고    scopus 로고
    • Roles of rapsyn and agrin in interaction of postsynaptic proteins with acetylcholine receptors
    • Fuhrer C, Gautam M, Sugiyama JE, Hall ZW (1999) Roles of rapsyn and agrin in interaction of postsynaptic proteins with acetylcholine receptors. J Neurosci 19:6405-6416.
    • (1999) J Neurosci , vol.19 , pp. 6405-6416
    • Fuhrer, C.1    Gautam, M.2    Sugiyama, J.E.3    Hall, Z.W.4
  • 18
    • 0029050847 scopus 로고
    • Failure of postsynaptic specialization to develop at neuromuscular junctions of rapsyn-deficient mice
    • Gautam M, Noakes PG, Mudd J, Nichol M, Chu GC, Sanes JR, Merlie JP (1995) Failure of postsynaptic specialization to develop at neuromuscular junctions of rapsyn-deficient mice. Nature 377:232-236.
    • (1995) Nature , vol.377 , pp. 232-236
    • Gautam, M.1    Noakes, P.G.2    Mudd, J.3    Nichol, M.4    Chu, G.C.5    Sanes, J.R.6    Merlie, J.P.7
  • 20
    • 0031750335 scopus 로고    scopus 로고
    • Lipid domain structure of the plasma membrane revealed by patching of membrane components
    • Harder T, Scheiffele P, Verkade P, Simons K (1998) Lipid domain structure of the plasma membrane revealed by patching of membrane components. J Cell Biol 141:929-942.
    • (1998) J Cell Biol , vol.141 , pp. 929-942
    • Harder, T.1    Scheiffele, P.2    Verkade, P.3    Simons, K.4
  • 21
    • 0037996880 scopus 로고    scopus 로고
    • Lipid rafts in the maintenance of synapses, dendritic spines, and surface AMPA receptor stability
    • Hering H, Lin CC, Sheng M (2003) Lipid rafts in the maintenance of synapses, dendritic spines, and surface AMPA receptor stability. J Neurosci 23:3262-3271.
    • (2003) J Neurosci , vol.23 , pp. 3262-3271
    • Hering, H.1    Lin, C.C.2    Sheng, M.3
  • 22
    • 0033055564 scopus 로고    scopus 로고
    • Detergent-insoluble glycosphingolipid/cholesterolrich membrane domains, lipid rafts and caveolae
    • Hooper NM (1999) Detergent-insoluble glycosphingolipid/cholesterolrich membrane domains, lipid rafts and caveolae. Mol Mem Biol 16:145-156.
    • (1999) Mol Mem Biol , vol.16 , pp. 145-156
    • Hooper, N.M.1
  • 23
    • 0023501151 scopus 로고
    • Antitumor activity via inhibition of glycosphingolipid biosynthesis
    • Inokuchi J, Mason I, Radin NS (1987) Antitumor activity via inhibition of glycosphingolipid biosynthesis. Cancer Lett 38:23-30.
    • (1987) Cancer Lett , vol.38 , pp. 23-30
    • Inokuchi, J.1    Mason, I.2    Radin, N.S.3
  • 24
    • 0033998793 scopus 로고    scopus 로고
    • The role of lipid rafts in T cell antigen receptor (TCR) signalling
    • Janes PW, Ley SC, Magee AI, Kabouridis PS (2001) The role of lipid rafts in T cell antigen receptor (TCR) signalling. Semin Immunol 12:23-34.
    • (2001) Semin Immunol , vol.12 , pp. 23-34
    • Janes, P.W.1    Ley, S.C.2    Magee, A.I.3    Kabouridis, P.S.4
  • 25
    • 0032402149 scopus 로고    scopus 로고
    • Specific agrin isoforms induce cAMP response element binding protein phosphorylation in hippocampal neurons
    • Ji RR, Bose CM, Lesuisse C, Qiu D, Huang JC, Zhang Q, Rupp F (1998) Specific agrin isoforms induce cAMP response element binding protein phosphorylation in hippocampal neurons. J Neurosci 18:9695-9702.
    • (1998) J Neurosci , vol.18 , pp. 9695-9702
    • Ji, R.R.1    Bose, C.M.2    Lesuisse, C.3    Qiu, D.4    Huang, J.C.5    Zhang, Q.6    Rupp, F.7
  • 26
    • 0033960535 scopus 로고    scopus 로고
    • Involvement of calpains in the destabilization of the acetylcholine receptor clusters in rat myotubes
    • Kim S, Nelson PG (2000) Involvement of calpains in the destabilization of the acetylcholine receptor clusters in rat myotubes. J Neurobiol 42:22-32.
    • (2000) J Neurobiol , vol.42 , pp. 22-32
    • Kim, S.1    Nelson, P.G.2
  • 27
    • 20444362083 scopus 로고    scopus 로고
    • Neurotransmitter acetylcholine negatively regulates neuromuscular synapse formation by a Cdk5-dependent mechanism
    • Lin W, Dominguez B, Yang J, Aryal P, Brandon EP, Gage FH, Lee KF (2005) Neurotransmitter acetylcholine negatively regulates neuromuscular synapse formation by a Cdk5-dependent mechanism. Neuron 46:569-579.
    • (2005) Neuron , vol.46 , pp. 569-579
    • Lin, W.1    Dominguez, B.2    Yang, J.3    Aryal, P.4    Brandon, E.P.5    Gage, F.H.6    Lee, K.F.7
  • 31
    • 0037109664 scopus 로고    scopus 로고
    • Rapsyn escorts the nicotinic acetylcholine receptor along the exocytic pathway via association with lipid rafts
    • Marchand S, Devillers-Thiery A, Pons S, Changeux JP, Cartaud J (2002) Rapsyn escorts the nicotinic acetylcholine receptor along the exocytic pathway via association with lipid rafts. J Neurosci 22:8891-8901.
    • (2002) J Neurosci , vol.22 , pp. 8891-8901
    • Marchand, S.1    Devillers-Thiery, A.2    Pons, S.3    Changeux, J.P.4    Cartaud, J.5
  • 33
    • 0032696038 scopus 로고    scopus 로고
    • Regulated migration of epidermal growth factor receptor from caveolae
    • Mineo C, Gill GN, Anderson RG (1999) Regulated migration of epidermal growth factor receptor from caveolae. J Biol Chem 274:30636-30643.
    • (1999) J Biol Chem , vol.274 , pp. 30636-30643
    • Mineo, C.1    Gill, G.N.2    Anderson, R.G.3
  • 34
    • 0037470047 scopus 로고    scopus 로고
    • Agrin regulates rapsyn interaction with surface acetylcholine receptors, and this underlies cytoskeletal anchoring and clustering
    • Moransard M, Borges LS, Willmann R, Marangi PA, Brenner HR, Ferns MJ, Fuhrer C (2003) Agrin regulates rapsyn interaction with surface acetylcholine receptors, and this underlies cytoskeletal anchoring and clustering. J Biol Chem 278:7350-7359.
    • (2003) J Biol Chem , vol.278 , pp. 7350-7359
    • Moransard, M.1    Borges, L.S.2    Willmann, R.3    Marangi, P.A.4    Brenner, H.R.5    Ferns, M.J.6    Fuhrer, C.7
  • 35
    • 9144272911 scopus 로고    scopus 로고
    • Reduction of glycosphingolipid levels in lipid rafts affects the expression state and function of glycosylphosphatidylinositol-anchored proteins but does not impair signal transduction via the T cell receptor
    • Nagafuku M, Kabayama K, Oka D, Kato A, Tani-ichi S, Shimada Y, Ohno-Iwashita Y, Yamasaki S, Saito T, Iwabuchi K, Hamaoka T, Inokuchi J, Kosugi A (2003) Reduction of glycosphingolipid levels in lipid rafts affects the expression state and function of glycosylphosphatidylinositol-anchored proteins but does not impair signal transduction via the T cell receptor. J Biol Chem 278:51920-51927.
    • (2003) J Biol Chem , vol.278 , pp. 51920-51927
    • Nagafuku, M.1    Kabayama, K.2    Oka, D.3    Kato, A.4    Tani-ichi, S.5    Shimada, Y.6    Ohno-Iwashita, Y.7    Yamasaki, S.8    Saito, T.9    Iwabuchi, K.10    Hamaoka, T.11    Inokuchi, J.12    Kosugi, A.13
  • 36
    • 0032875098 scopus 로고    scopus 로고
    • Fatty acylation of proteins: New insights into membrane targeting of myristoylated and palmitoylated proteins
    • Resh MD (1999) Fatty acylation of proteins: new insights into membrane targeting of myristoylated and palmitoylated proteins. Biochim Biophys Acta 1451:1-16.
    • (1999) Biochim Biophys Acta , vol.1451 , pp. 1-16
    • Resh, M.D.1
  • 37
    • 0035511932 scopus 로고    scopus 로고
    • Induction, assembly, maturation and maintenance of a postsynaptic apparatus
    • Sanes JR, Lichtman JW (2001) Induction, assembly, maturation and maintenance of a postsynaptic apparatus. Nat Rev Neurosci 2:791-805.
    • (2001) Nat Rev Neurosci , vol.2 , pp. 791-805
    • Sanes, J.R.1    Lichtman, J.W.2
  • 38
    • 0024377837 scopus 로고
    • Thermodynamics of intersubunit interactions in cholera toxin upon binding to the oligosaccharide portion of its cell surface receptor, ganglioside GM1
    • Schon A, Freire E (1989) Thermodynamics of intersubunit interactions in cholera toxin upon binding to the oligosaccharide portion of its cell surface receptor, ganglioside GM1. Biochemistry 28:5019-5024.
    • (1989) Biochemistry , vol.28 , pp. 5019-5024
    • Schon, A.1    Freire, E.2
  • 39
    • 0030949124 scopus 로고    scopus 로고
    • Functional rafts in cell membranes
    • Simons K, Ikonen E (1997) Functional rafts in cell membranes. Nature 387:569-572.
    • (1997) Nature , vol.387 , pp. 569-572
    • Simons, K.1    Ikonen, E.2
  • 40
    • 0034304851 scopus 로고    scopus 로고
    • Lipid rafts and signal transduction
    • Simons K, Toomre D (2001) Lipid rafts and signal transduction. Nat Rev Mol Cell Biol 1:31-39.
    • (2001) Nat Rev Mol Cell Biol , vol.1 , pp. 31-39
    • Simons, K.1    Toomre, D.2
  • 41
    • 0029912981 scopus 로고    scopus 로고
    • Co-purification and direct interaction of Ras with caveolin, an integral membrane protein of caveolae microdomains. Detergent-free purification of caveolae microdomains
    • Song KS, Li S, Okamoto T, Quilliam LA, Sargiacomo M, Lisanti MP (1996) Co-purification and direct interaction of Ras with caveolin, an integral membrane protein of caveolae microdomains. Detergent-free purification of caveolae microdomains. J Biol Chem 271:9690-9697.
    • (1996) J Biol Chem , vol.271 , pp. 9690-9697
    • Song, K.S.1    Li, S.2    Okamoto, T.3    Quilliam, L.A.4    Sargiacomo, M.5    Lisanti, M.P.6
  • 43
    • 0033232527 scopus 로고    scopus 로고
    • Regulation of neuregulin-mediated AChR synthesis by protein tyrosine phosphatase SHP2
    • Tanowitz M, Si J, Yu D-H, Feng G-S, Mei L (1999) Regulation of neuregulin-mediated AChR synthesis by protein tyrosine phosphatase SHP2. J Neurosci 19:9426-9435.
    • (1999) J Neurosci , vol.19 , pp. 9426-9435
    • Tanowitz, M.1    Si, J.2    Yu, D.-H.3    Feng, G.-S.4    Mei, L.5
  • 44
    • 0343844464 scopus 로고    scopus 로고
    • Surgical denervation increases protein tyrosine phosphatase activity in skeletal muscle
    • Tanowitz MB, Mei L (1996) Surgical denervation increases protein tyrosine phosphatase activity in skeletal muscle. Brain Res 712:299-306.
    • (1996) Brain Res , vol.712 , pp. 299-306
    • Tanowitz, M.B.1    Mei, L.2
  • 45
    • 0033625038 scopus 로고    scopus 로고
    • GFRalpha-mediated localization of RET to lipid rafts is required for effective downstream signaling, differentiation, and neuronal survival
    • Tansey MG, Baloh RH, Milbrandt J, Johnson Jr EM (2001) GFRalpha-mediated localization of RET to lipid rafts is required for effective downstream signaling, differentiation, and neuronal survival. Neuron 25:611-623.
    • (2001) Neuron , vol.25 , pp. 611-623
    • Tansey, M.G.1    Baloh, R.H.2    Milbrandt, J.3    Johnson Jr., E.M.4
  • 46
    • 3843058014 scopus 로고    scopus 로고
    • Neuregulin inhibits acetylcholine receptor aggregation in myotubes
    • Trinidad JC, Cohen JB (2004) Neuregulin inhibits acetylcholine receptor aggregation in myotubes. J Biol Chem 279:31622-31628.
    • (2004) J Biol Chem , vol.279 , pp. 31622-31628
    • Trinidad, J.C.1    Cohen, J.B.2
  • 47
    • 0023729036 scopus 로고
    • ++ and phorbol ester
    • ++ and phorbol ester. J Cell Biol 107:267-278.
    • (1988) J Cell Biol , vol.107 , pp. 267-278
    • Wallace, B.G.1
  • 48
    • 0026433409 scopus 로고
    • The mechanism of agrin-induced acetylcholine receptor aggregation
    • Wallace BG (1991) The mechanism of agrin-induced acetylcholine receptor aggregation. Philos Trans R Soc Lond B Biol Sci 331:273-280.
    • (1991) Philos Trans R Soc Lond B Biol Sci , vol.331 , pp. 273-280
    • Wallace, B.G.1
  • 49
    • 0028956758 scopus 로고
    • Regulation of the interaction of nicotinic acetylcholine receptors with the cytoskeleton by agrin-activated protein tyrosine kinase
    • Wallace BG (1995) Regulation of the interaction of nicotinic acetylcholine receptors with the cytoskeleton by agrin-activated protein tyrosine kinase. J Cell Biol 128:1121-1129.
    • (1995) J Cell Biol , vol.128 , pp. 1121-1129
    • Wallace, B.G.1
  • 50
    • 0034631836 scopus 로고    scopus 로고
    • Agrin-induced acetylcholine receptor clustering is mediated by the small guanosine triphosphatases Rac and Cdc42
    • Weston C, Yee B, Hod E, Prives J (2000) Agrin-induced acetylcholine receptor clustering is mediated by the small guanosine triphosphatases Rac and Cdc42. J Cell Biol 150:205-212.
    • (2000) J Cell Biol , vol.150 , pp. 205-212
    • Weston, C.1    Yee, B.2    Hod, E.3    Prives, J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.