메뉴 건너뛰기




Volumn 22, Issue 1-2, 2004, Pages 13-18

Overexpression of human cystatin C in transgenic mice does not affect levels of endogenous brain amyloid β peptide

Author keywords

amyloid precursor protein; Alzheimer's disease; Amyloid ; Cystatin C; Protease inhibitor

Indexed keywords

AMYLOID BETA PROTEIN; CYSTATIN C; AMYLOID PRECURSOR PROTEIN; CYSTATIN; CYSTEINE PROTEINASE;

EID: 3042820505     PISSN: 08958696     EISSN: None     Source Type: Journal    
DOI: 10.1385/JMN:22:1-2:13     Document Type: Conference Paper
Times cited : (26)

References (40)
  • 1
    • 0021236724 scopus 로고
    • The place of human γ trace (cystatin C) amongst the cysteine proteinase inhibitors
    • Barrett A. J., Davies M. E., and Grubb A. O. (1984) The place of human γ trace (cystatin C) amongst the cysteine proteinase inhibitors. Biochem. Biophys. Res. Commun. 120, 631-636.
    • (1984) Biochem. Biophys. Res. Commun. , vol.120 , pp. 631-636
    • Barrett, A.J.1    Davies, M.E.2    Grubb, A.O.3
  • 3
    • 0026806875 scopus 로고
    • Cystatins-inhibitors of cysteine proteinases
    • Bobek L. A. and Levine M. J. (1992) Cystatins-inhibitors of cysteine proteinases. Crit. Rev. Oral Biol. Med. 3, 307-332.
    • (1992) Crit. Rev. Oral Biol. Med. , vol.3 , pp. 307-332
    • Bobek, L.A.1    Levine, M.J.2
  • 4
    • 0035047801 scopus 로고    scopus 로고
    • Distinct properties of wild-type and the amyloidogenic human cystatin C variant of hereditary cerebral hemorrhage with amyloidosis, Icelandic type
    • Calero M., Pawlik M., Soto C., Castaño E. M., Sigurdsson E., Kumar A., et al. (2001) Distinct properties of wild-type and the amyloidogenic human cystatin C variant of hereditary cerebral hemorrhage with amyloidosis, Icelandic type. J. Neurochem. 77, 628-637.
    • (2001) J. Neurochem. , vol.77 , pp. 628-637
    • Calero, M.1    Pawlik, M.2    Soto, C.3    Castaño, E.M.4    Sigurdsson, E.5    Kumar, A.6
  • 5
    • 0020604495 scopus 로고
    • Amyloid fibril in hereditary cerebral hemorrhage with amyloidosis (HCHWA) is related to the gastrenteropancreatic neuroendocrine protein, γ trace
    • Cohen D. H., Feiner H., Jensson O., and Frangione B. (1983) Amyloid fibril in hereditary cerebral hemorrhage with amyloidosis (HCHWA) is related to the gastrenteropancreatic neuroendocrine protein, γ trace. J. Exp. Med. 158, 623-628.
    • (1983) J. Exp. Med. , vol.158 , pp. 623-628
    • Cohen, D.H.1    Feiner, H.2    Jensson, O.3    Frangione, B.4
  • 6
    • 0034718576 scopus 로고    scopus 로고
    • A polymorphism in the cystatin C gene is a novel risk factor for late-onset Alzheimer's disease
    • Crawford F. C., Freeman M. J., Schinka J. A., Abdullah L. I., Gold M., Hartman R., et al. (2000) A polymorphism in the cystatin C gene is a novel risk factor for late-onset Alzheimer's disease. Neurology 55, 763-768.
    • (2000) Neurology , vol.55 , pp. 763-768
    • Crawford, F.C.1    Freeman, M.J.2    Schinka, J.A.3    Abdullah, L.I.4    Gold, M.5    Hartman, R.6
  • 7
    • 0037176812 scopus 로고    scopus 로고
    • A polymorphism in the cystatin C promoter region is not associated with an increased risk of AD
    • Dodel R. C., Du Y., Depboylu C., Kurz A., Eastwood B., Farlow M., et al. (2002) A polymorphism in the cystatin C promoter region is not associated with an increased risk of AD. Neurology 58, 664.
    • (2002) Neurology , vol.58 , pp. 664
    • Dodel, R.C.1    Du, Y.2    Depboylu, C.3    Kurz, A.4    Eastwood, B.5    Farlow, M.6
  • 8
    • 0025295039 scopus 로고
    • Cleavage of amyloid β peptide during constitutive processing of its precursor
    • Esch F. S., Keim P. S., Beattie E. C., Blacher R. W., Culwell A. R., Oltersdorf T., et al. (1990) Cleavage of amyloid β peptide during constitutive processing of its precursor. Science 248, 1122-1124.
    • (1990) Science , vol.248 , pp. 1122-1124
    • Esch, F.S.1    Keim, P.S.2    Beattie, E.C.3    Blacher, R.W.4    Culwell, A.R.5    Oltersdorf, T.6
  • 9
    • 0023886160 scopus 로고
    • Purification of the cystatin C-like inhibitors from urine of nephropathic rats
    • Esnard A., Esnard F., and Gauthier F. (1988) Purification of the cystatin C-like inhibitors from urine of nephropathic rats. Biol. Chem. Hoppe-Seyler. 369 (Suppl.), 219-222.
    • (1988) Biol. Chem. Hoppe-Seyler. , vol.369 , Issue.SUPPL. , pp. 219-222
    • Esnard, A.1    Esnard, F.2    Gauthier, F.3
  • 11
    • 0033733370 scopus 로고    scopus 로고
    • Genetic association of a cystatin C gene polymorphism with late-onset Alzheimer disease
    • Finckh U., von Der Kammer H., Velden J., Michel T., Andresen B., Deng A., et al. (2000) Genetic association of a cystatin C gene polymorphism with late-onset Alzheimer disease. Arch. Neurol. 57, 1579-1583.
    • (2000) Arch. Neurol. , vol.57 , pp. 1579-1583
    • Finckh, U.1    Von Der Kammer, H.2    Velden, J.3    Michel, T.4    Andresen, B.5    Deng, A.6
  • 12
    • 0011766298 scopus 로고
    • Amyloid fibrils in hereditary cerebral hemorrhage with amyloidosis is a variant of γ trace basic protein (cystatin C)
    • Ghiso J., Jensson O., and Frangione B. (1986) Amyloid fibrils in hereditary cerebral hemorrhage with amyloidosis is a variant of γ trace basic protein (cystatin C). Proc. Natl. Acad. Sci. USA 83, 2974-2978.
    • (1986) Proc. Natl. Acad. Sci. USA , vol.83 , pp. 2974-2978
    • Ghiso, J.1    Jensson, O.2    Frangione, B.3
  • 13
    • 0021256895 scopus 로고
    • Alzheimer's disease: Initial report of the purification and characterization of a novel cerebrovascular amyloid protein
    • Glenner G. G. and Wong C. W. (1984) Alzheimer's disease: initial report of the purification and characterization of a novel cerebrovascular amyloid protein. Biochem. Biophys. Res. Commun. 120, 885-890.
    • (1984) Biochem. Biophys. Res. Commun. , vol.120 , pp. 885-890
    • Glenner, G.G.1    Wong, C.W.2
  • 15
    • 0028335790 scopus 로고
    • Co-localization of β/A4 and cystatin C in cortical blood vessels in Dutch, but not in Icelandic hereditary cerebral hemorrhage with amyloidosis
    • Haan J., Maat-Schieman M. L. C., van Duinen S. G., Jensson O., Thorsteinsson L., and Roos R. A. C. (1994) Co-localization of β/A4 and cystatin C in cortical blood vessels in Dutch, but not in Icelandic hereditary cerebral hemorrhage with amyloidosis. Acta Neurol. Scand. 89, 367-371.
    • (1994) Acta Neurol. Scand. , vol.89 , pp. 367-371
    • Haan, J.1    Maat-Schieman, M.L.C.2    Van Duinen, S.G.3    Jensson, O.4    Thorsteinsson, L.5    Roos, R.A.C.6
  • 17
    • 0014061584 scopus 로고
    • Trace proteins in biological fluids. IV. Physicochemical properties and sites of formation of γ trace and β trace proteins
    • Hochwald G. M., Pepe A. J., and Thorbecke G. J. (1967) Trace proteins in biological fluids. IV. Physicochemical properties and sites of formation of γ trace and β trace proteins. Proc. Soc. Exp. Med. 124, 961-966.
    • (1967) Proc. Soc. Exp. Med. , vol.124 , pp. 961-966
    • Hochwald, G.M.1    Pepe, A.J.2    Thorbecke, G.J.3
  • 18
    • 0033435169 scopus 로고    scopus 로고
    • Decreased metastatic spread in mice homozygous for a null allele of the cystatin C protease inhibitor gene
    • Huh C. G., Hakansson K., Nathanson C. M., Thorgeirsson U. P., Jonsson N., Grubb A., et al. (1999) Decreased metastatic spread in mice homozygous for a null allele of the cystatin C protease inhibitor gene. Mol. Pathol. 52, 332-340.
    • (1999) Mol. Pathol. , vol.52 , pp. 332-340
    • Huh, C.G.1    Hakansson, K.2    Nathanson, C.M.3    Thorgeirsson, U.P.4    Jonsson, N.5    Grubb, A.6
  • 19
    • 0027314209 scopus 로고
    • Cerebral amyloid angiopathy: A significant cause of cerebellar as well as lobar cerebral hemorrhage in the elderly
    • Itoh Y., Yamada M., Hayakawa M., Otomo E., and Miyatake T. (1993) Cerebral amyloid angiopathy: a significant cause of cerebellar as well as lobar cerebral hemorrhage in the elderly. J. Neurol. Sci. 116, 135-141.
    • (1993) J. Neurol. Sci. , vol.116 , pp. 135-141
    • Itoh, Y.1    Yamada, M.2    Hayakawa, M.3    Otomo, E.4    Miyatake, T.5
  • 20
    • 0023105114 scopus 로고
    • The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor
    • Kang J., Lemaire H. G., Unterbeck A., Salbaum J. M., Masters C. L., Grzeschik K. H., et al. (1987) The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor. Nature 325, 733-736.
    • (1987) Nature , vol.325 , pp. 733-736
    • Kang, J.1    Lemaire, H.G.2    Unterbeck, A.3    Salbaum, J.M.4    Masters, C.L.5    Grzeschik, K.H.6
  • 21
    • 0024504095 scopus 로고
    • Stroke in Icelandic patients with hereditary amyloid angiopathy is related to a mutation in the cystatin C gene, an inhibitor of cysteine proteases
    • Levy E., Lopez-Otin C., Ghiso J., Geltner D., and Frangione B. (1989) Stroke in Icelandic patients with hereditary amyloid angiopathy is related to a mutation in the cystatin C gene, an inhibitor of cysteine proteases. J. Exp. Med. 169, 1771-1778.
    • (1989) J. Exp. Med. , vol.169 , pp. 1771-1778
    • Levy, E.1    Lopez-Otin, C.2    Ghiso, J.3    Geltner, D.4    Frangione, B.5
  • 23
    • 0025344074 scopus 로고
    • Immunohistochemical characterization of cerebrovascular amyloid in 46 autopsied cases using antibodies to β protein and cystatin C
    • Maruyama K., Ikeda S., Ishihara T., Allsop D., and Yanagisawa N. (1990) Immunohistochemical characterization of cerebrovascular amyloid in 46 autopsied cases using antibodies to β protein and cystatin C. Stroke 21, 397-403.
    • (1990) Stroke , vol.21 , pp. 397-403
    • Maruyama, K.1    Ikeda, S.2    Ishihara, T.3    Allsop, D.4    Yanagisawa, N.5
  • 24
    • 0035943066 scopus 로고    scopus 로고
    • Lack of an association between cystatin C gene polymorphisms in Japanese patients with Alzheimer's disease
    • Maruyama H., Izumi Y., Oda M., Torii T., Morino H., Toji H., et al. (2001) Lack of an association between cystatin C gene polymorphisms in Japanese patients with Alzheimer's disease. Neurology 57, 337-339.
    • (2001) Neurology , vol.57 , pp. 337-339
    • Maruyama, H.1    Izumi, Y.2    Oda, M.3    Torii, T.4    Morino, H.5    Toji, H.6
  • 26
    • 0029999658 scopus 로고    scopus 로고
    • The molecular pathology of hereditary cystatin C amyloid angiopathy causing brain hemorrhage
    • Olafsson I., Thorsteinsson L., and Jensson O. (1996) The molecular pathology of hereditary cystatin C amyloid angiopathy causing brain hemorrhage. Brain Pathol. 6, 121-126.
    • (1996) Brain Pathol. , vol.6 , pp. 121-126
    • Olafsson, I.1    Thorsteinsson, L.2    Jensson, O.3
  • 27
    • 0036301635 scopus 로고    scopus 로고
    • A second locus for very-late-onset Alzheimer disease: A genome scan reveals linkage to 20p and epistasis between 20p and the amyloid precursor protein region
    • Olson J. M., Goddard K. A., and Dudek D. M. (2002) A second locus for very-late-onset Alzheimer disease: a genome scan reveals linkage to 20p and epistasis between 20p and the amyloid precursor protein region. Am. J. Hum. Genet. 71, 154-161.
    • (2002) Am. J. Hum. Genet. , vol.71 , pp. 154-161
    • Olson, J.M.1    Goddard, K.A.2    Dudek, D.M.3
  • 28
    • 0029097834 scopus 로고
    • Cystatin C, a protease inhibitor, in degenerating rat hippocampal neurons following transient forebrain ischemia
    • Palm D. E., Knuckey N. W., Primiano M. J., Spangenberger A. G., and Johanson C. E. (1995) Cystatin C, a protease inhibitor, in degenerating rat hippocampal neurons following transient forebrain ischemia. Brain Res. 691, 1-8.
    • (1995) Brain Res. , vol.691 , pp. 1-8
    • Palm, D.E.1    Knuckey, N.W.2    Primiano, M.J.3    Spangenberger, A.G.4    Johanson, C.E.5
  • 30
    • 0036167050 scopus 로고    scopus 로고
    • Normal brain development in PS1 hypomorphic mice with markedly reduced γ-secretase cleavage of βAPP
    • Rozmahel R., Huang J., Chen F., Liang Y., Nguyen V., Ikeda M., et al. (2002) Normal brain development in PS1 hypomorphic mice with markedly reduced γ-secretase cleavage of βAPP. Neurobiol. Aging 23, 187-194.
    • (2002) Neurobiol. Aging , vol.23 , pp. 187-194
    • Rozmahel, R.1    Huang, J.2    Chen, F.3    Liang, Y.4    Nguyen, V.5    Ikeda, M.6
  • 32
    • 0026646605 scopus 로고
    • Isolation and quantification of soluble Alzheimer's β-peptide from biological fluids
    • Seubert P., Vigo-Pelfrey C., Esch F., Lee M., Dovey H., Davis D., et al. (1992) Isolation and quantification of soluble Alzheimer's β-peptide from biological fluids. Nature 359, 325-327.
    • (1992) Nature , vol.359 , pp. 325-327
    • Seubert, P.1    Vigo-Pelfrey, C.2    Esch, F.3    Lee, M.4    Dovey, H.5    Davis, D.6
  • 33
    • 0026760261 scopus 로고
    • Production of the Alzheimer amyloid β protein by normal proteolytic processing
    • Shoji M., Golde T. E., Ghiso J., Cheung T. T., Estus S., Shaffer L. M., et al. (1992) Production of the Alzheimer amyloid β protein by normal proteolytic processing. Science 258, 126-129.
    • (1992) Science , vol.258 , pp. 126-129
    • Shoji, M.1    Golde, T.E.2    Ghiso, J.3    Cheung, T.T.4    Estus, S.5    Shaffer, L.M.6
  • 34
    • 0025373508 scopus 로고
    • Evidence that β-amyloid protein in Alzheimer's disease is not derived by normal processing
    • Sisodia S. S., Koo E. H., Beyreuther K., Unterbeck A., and Price D. L. (1990) Evidence that β-amyloid protein in Alzheimer's disease is not derived by normal processing. Science 248, 492-495.
    • (1990) Science , vol.248 , pp. 492-495
    • Sisodia, S.S.1    Koo, E.H.2    Beyreuther, K.3    Unterbeck, A.4    Price, D.L.5
  • 35
    • 0034877781 scopus 로고    scopus 로고
    • Increased cystatin C in astrocytes of transgenic mice expressing the K670N-M671L mutation of the amyloid precursor protein and deposition in brain amyloid plaques
    • Steinhoff T., Moritz E., Wollmer M. A., Mohajeri M. H., Kins S., and Nitsch R. M. (2001) Increased cystatin C in astrocytes of transgenic mice expressing the K670N-M671L mutation of the amyloid precursor protein and deposition in brain amyloid plaques. Neurobiol. Dis. 8, 647-654.
    • (2001) Neurobiol. Dis. , vol.8 , pp. 647-654
    • Steinhoff, T.1    Moritz, E.2    Wollmer, M.A.3    Mohajeri, M.H.4    Kins, S.5    Nitsch, R.M.6
  • 36
    • 0033635021 scopus 로고    scopus 로고
    • FGF-2-Responsive neural stem cell proliferation requires CCg, a novel autocrine/paracrine cofactor
    • Taupin P., Ray J., Fischer W. H., Suhr S. T., Hakansson K., Grubb A., and Gage F. H. (2000) FGF-2-Responsive neural stem cell proliferation requires CCg, a novel autocrine/paracrine cofactor. Neuron 28, 385-397.
    • (2000) Neuron , vol.28 , pp. 385-397
    • Taupin, P.1    Ray, J.2    Fischer, W.H.3    Suhr, S.T.4    Hakansson, K.5    Grubb, A.6    Gage, F.H.7
  • 37
    • 0025817602 scopus 로고
    • The cystatins: Protein inhibitors of cysteine proteinases
    • Turk V. and Bode W. (1991) The cystatins: protein inhibitors of cysteine proteinases. FEBS Lett. 285, 213-219.
    • (1991) FEBS Lett. , vol.285 , pp. 213-219
    • Turk, V.1    Bode, W.2
  • 38
    • 0038472441 scopus 로고    scopus 로고
    • Cystatin C colocalizes with amyloid-β and coimmunoprecipitates with amyloid β precursor protein in sporadic inclusion-body myositis muscles
    • Vattemi G., Engel W. K., McFerrin J., and Askanas V. (2003) Cystatin C colocalizes with amyloid-β and coimmunoprecipitates with amyloid β precursor protein in sporadic inclusion-body myositis muscles. J. Neurochem. 85, 1539-1546.
    • (2003) J. Neurochem. , vol.85 , pp. 1539-1546
    • Vattemi, G.1    Engel, W.K.2    McFerrin, J.3    Askanas, V.4
  • 39
    • 0025371978 scopus 로고
    • Immunoreactive A4 and γ trace peptide colocalization in amyloidotic arteriolar lesions in brains of patients with Alzheimer's disease
    • Vinters H. V., Nishimura G. S., Secor D. L., and Pardridge W. M. (1990) Immunoreactive A4 and γ trace peptide colocalization in amyloidotic arteriolar lesions in brains of patients with Alzheimer's disease. Am. J. Pathol. 137, 233-240.
    • (1990) Am. J. Pathol. , vol.137 , pp. 233-240
    • Vinters, H.V.1    Nishimura, G.S.2    Secor, D.L.3    Pardridge, W.M.4
  • 40
    • 0029829459 scopus 로고    scopus 로고
    • Cystatin C: Icelandic-like mutation in an animal model of cerebrovascular β amyloidosis
    • Wei L., Walker L. C., and Levy E. (1996) Cystatin C: Icelandic-like mutation in an animal model of cerebrovascular β amyloidosis. Stroke 27, 2080-2085.
    • (1996) Stroke , vol.27 , pp. 2080-2085
    • Wei, L.1    Walker, L.C.2    Levy, E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.