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Volumn 4, Issue 6, 2009, Pages

Erratum: Expression of concern: P63 promotes cell survival through fatty acid synthase (PLoS ONE (2019)4:6(e5877) Doi: 10.1371/journal.pone.0005877);p63 promotes cell survival through fatty acid synthase

Author keywords

[No Author keywords available]

Indexed keywords

FATTY ACID SYNTHASE; PROTEIN KINASE B; PROTEIN P63; CKAP4 PROTEIN, HUMAN; DNA BINDING PROTEIN; ISOPROTEIN; MEMBRANE PROTEIN; MYRISTIC ACID DERIVATIVE; NUCLEAR PROTEIN; TUMOR SUPPRESSOR PROTEIN; TUMOR SUPPRESSOR PROTEIN P73;

EID: 67650077386     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0219869     Document Type: Erratum
Times cited : (26)

References (65)
  • 1
    • 0032161624 scopus 로고    scopus 로고
    • p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities
    • Yang A, Kaghad M, Wang Y, Gillett E, Fleming MD, et al. (1998) p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities. Mol Cell 2: 305-316.
    • (1998) Mol Cell , vol.2 , pp. 305-316
    • Yang, A.1    Kaghad, M.2    Wang, Y.3    Gillett, E.4    Fleming, M.D.5
  • 2
    • 0030884751 scopus 로고    scopus 로고
    • A novel protein with strong homology to the tumor suppressor p53
    • Schmale H, Bamberger C (1997) A novel protein with strong homology to the tumor suppressor p53. Oncogene 15: 1363-1367.
    • (1997) Oncogene , vol.15 , pp. 1363-1367
    • Schmale, H.1    Bamberger, C.2
  • 3
    • 0031852337 scopus 로고    scopus 로고
    • Cloning and functional analysis of human p51, which structurally and functionally resembles p53
    • Osada M, Ohba M, Kawahara C, Ishioka C, Kanamaru R, et al. (1998) Cloning and functional analysis of human p51, which structurally and functionally resembles p53. Nat Med 4: 839-843.
    • (1998) Nat Med , vol.4 , pp. 839-843
    • Osada, M.1    Ohba, M.2    Kawahara, C.3    Ishioka, C.4    Kanamaru, R.5
  • 4
    • 0033594485 scopus 로고    scopus 로고
    • p63 is essential for regenerative proliferation in limb, craniofacial and epithelial development
    • Yang A, Schweitzer R, Sun D, Kaghad M, Walker N, et al. (1999) p63 is essential for regenerative proliferation in limb, craniofacial and epithelial development. Nature 398: 714-718.
    • (1999) Nature , vol.398 , pp. 714-718
    • Yang, A.1    Schweitzer, R.2    Sun, D.3    Kaghad, M.4    Walker, N.5
  • 5
    • 0033637118 scopus 로고    scopus 로고
    • p63 is a prostate basal cell marker and is required for prostate development
    • Signoretti S, Waltregny D, Dilks J, Isaac B, Lin D, et al. (2000) p63 is a prostate basal cell marker and is required for prostate development. Am J Pathol 157: 1769-1775.
    • (2000) Am J Pathol , vol.157 , pp. 1769-1775
    • Signoretti, S.1    Waltregny, D.2    Dilks, J.3    Isaac, B.4    Lin, D.5
  • 6
    • 0033881433 scopus 로고    scopus 로고
    • Down-regulation of p63 is required for epidermal UV-B-induced apoptosis
    • Liefer KM, Koster MI, Wang XJ, Yang A, McKeon F, et al. (2000) Down-regulation of p63 is required for epidermal UV-B-induced apoptosis. Cancer Res 60: 4016-4020.
    • (2000) Cancer Res , vol.60 , pp. 4016-4020
    • Liefer, K.M.1    Koster, M.I.2    Wang, X.J.3    Yang, A.4    McKeon, F.5
  • 7
    • 0036144565 scopus 로고    scopus 로고
    • Growth factor requirements and basal phenotype of an immortalized mammary epithelial cell line
    • DiRenzo J, Signoretti S, Nakamura N, Rivera-Gonzalez R, Sellers W, et al. (2002) Growth factor requirements and basal phenotype of an immortalized mammary epithelial cell line. Cancer Res 62: 89-98.
    • (2002) Cancer Res , vol.62 , pp. 89-98
    • DiRenzo, J.1    Signoretti, S.2    Nakamura, N.3    Rivera-Gonzalez, R.4    Sellers, W.5
  • 10
    • 0033594491 scopus 로고    scopus 로고
    • p63 is a p53 homologue required for limb and epidermal morphogenesis
    • Mills AA, Zheng B, Wang XJ, Vogel H, Roop DR, et al. (1999) p63 is a p53 homologue required for limb and epidermal morphogenesis. Nature 398: 708-713.
    • (1999) Nature , vol.398 , pp. 708-713
    • Mills, A.A.1    Zheng, B.2    Wang, X.J.3    Vogel, H.4    Roop, D.R.5
  • 11
    • 34247511981 scopus 로고    scopus 로고
    • p63 Is essential for the proliferative potential of stem cells in stratified epithelia
    • Senoo M, Pinto F, Crum CP, McKeon F (2007) p63 Is essential for the proliferative potential of stem cells in stratified epithelia. Cell 129: 523-536.
    • (2007) Cell , vol.129 , pp. 523-536
    • Senoo, M.1    Pinto, F.2    Crum, C.P.3    McKeon, F.4
  • 12
    • 0036791603 scopus 로고    scopus 로고
    • Loss of p63 expression is associated with tumor progression in bladder cancer
    • Urist MJ, Di Como CJ, Lu ML, Charytonowicz E, Verbel D, et al. (2002) Loss of p63 expression is associated with tumor progression in bladder cancer. Am J Pathol 161: 1199-1206.
    • (2002) Am J Pathol , vol.161 , pp. 1199-1206
    • Urist, M.J.1    Di Como, C.J.2    Lu, M.L.3    Charytonowicz, E.4    Verbel, D.5
  • 14
    • 33744830912 scopus 로고    scopus 로고
    • p63 heterozygous mutant mice are not prone to spontaneous or chemically induced tumors
    • Keyes WM, Vogel H, Koster MI, Guo X, Qi Y, et al. (2006) p63 heterozygous mutant mice are not prone to spontaneous or chemically induced tumors. Proc Natl Acad Sci U S A 103: 8435-8440.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 8435-8440
    • Keyes, W.M.1    Vogel, H.2    Koster, M.I.3    Guo, X.4    Qi, Y.5
  • 16
    • 17444390129 scopus 로고    scopus 로고
    • Tumor predisposition in mice mutant for p63 and p73: Evidence for broader tumor suppressor functions for the p53 family
    • Flores ER, Sengupta S, Miller JB, Newman JJ, Bronson R, et al. (2005) Tumor predisposition in mice mutant for p63 and p73: evidence for broader tumor suppressor functions for the p53 family. Cancer Cell 7: 363-373.
    • (2005) Cancer Cell , vol.7 , pp. 363-373
    • Flores, E.R.1    Sengupta, S.2    Miller, J.B.3    Newman, J.J.4    Bronson, R.5
  • 17
    • 0034099274 scopus 로고    scopus 로고
    • Frequent gain of the p40/p51/p63 gene locus in primary head and neck squamous cell carcinoma
    • Yamaguchi K, Wu L, Caballero OL, Hibi K, Trink B, et al. (2000) Frequent gain of the p40/p51/p63 gene locus in primary head and neck squamous cell carcinoma. Int J Cancer 86: 684-689.
    • (2000) Int J Cancer , vol.86 , pp. 684-689
    • Yamaguchi, K.1    Wu, L.2    Caballero, O.L.3    Hibi, K.4    Trink, B.5
  • 18
    • 0033372016 scopus 로고    scopus 로고
    • Association of p63 with proliferative potential in normal and neoplastic human keratinocytes
    • Parsa R, Yang A, McKeon F, Green H (1999) Association of p63 with proliferative potential in normal and neoplastic human keratinocytes. J Invest Dermatol 113: 1099-1105.
    • (1999) J Invest Dermatol , vol.113 , pp. 1099-1105
    • Parsa, R.1    Yang, A.2    McKeon, F.3    Green, H.4
  • 19
    • 0034234312 scopus 로고    scopus 로고
    • Frequent alteration of p63 expression in human primary bladder carcinomas
    • Park BJ, Lee SJ, Kim JI, Lee SJ, Lee CH, et al. (2000) Frequent alteration of p63 expression in human primary bladder carcinomas. Cancer Res 60: 3370-3374.
    • (2000) Cancer Res , vol.60 , pp. 3370-3374
    • Park, B.J.1    Lee, S.J.2    Kim, J.I.3    Lee, S.J.4    Lee, C.H.5
  • 20
    • 0036214558 scopus 로고    scopus 로고
    • Differential expression of p53 gene family members p63 and p73 in head and neck squamous tumorigenesis
    • Choi HR, Batsakis JG, Zhan F, Sturgis E, Luna MA, et al. (2002) Differential expression of p53 gene family members p63 and p73 in head and neck squamous tumorigenesis. Hum Pathol 33: 158-164.
    • (2002) Hum Pathol , vol.33 , pp. 158-164
    • Choi, H.R.1    Batsakis, J.G.2    Zhan, F.3    Sturgis, E.4    Luna, M.A.5
  • 21
    • 1842609721 scopus 로고    scopus 로고
    • How many mutant p53 molecules are needed to inactivate a tetramer?
    • Chan WM, Siu WY, Lau A, Poon RY (2004) How many mutant p53 molecules are needed to inactivate a tetramer? Mol Cell Biol 24: 3536-3551.
    • (2004) Mol Cell Biol , vol.24 , pp. 3536-3551
    • Chan, W.M.1    Siu, W.Y.2    Lau, A.3    Poon, R.Y.4
  • 22
    • 30344450404 scopus 로고    scopus 로고
    • p63 mediates survival in squamous cell carcinoma by suppression of p73-dependent apoptosis
    • Rocco JW, Leong CO, Kuperwasser N, DeYoung MP, Ellisen LW (2006) p63 mediates survival in squamous cell carcinoma by suppression of p73-dependent apoptosis. Cancer Cell 9: 45-56.
    • (2006) Cancer Cell , vol.9 , pp. 45-56
    • Rocco, J.W.1    Leong, C.O.2    Kuperwasser, N.3    DeYoung, M.P.4    Ellisen, L.W.5
  • 23
    • 33646371246 scopus 로고    scopus 로고
    • GPX2, a direct target of p63, inhibits oxidative stress-induced apoptosis in a p53-dependent manner
    • Yan W, Chen X (2006) GPX2, a direct target of p63, inhibits oxidative stress-induced apoptosis in a p53-dependent manner. J Biol Chem 281: 7856-7862.
    • (2006) J Biol Chem , vol.281 , pp. 7856-7862
    • Yan, W.1    Chen, X.2
  • 24
    • 13444250890 scopus 로고    scopus 로고
    • DeltaNp63alpha up-regulates the Hsp70 gene in human cancer
    • Wu G, Osada M, Guo Z, Fomenkov A, Begum S, et al. (2005) DeltaNp63alpha up-regulates the Hsp70 gene in human cancer. Cancer Res 65: 758-766.
    • (2005) Cancer Res , vol.65 , pp. 758-766
    • Wu, G.1    Osada, M.2    Guo, Z.3    Fomenkov, A.4    Begum, S.5
  • 25
    • 0037377761 scopus 로고    scopus 로고
    • The Delta Np63 alpha phosphoprotein binds the p21 and 14-3-3 sigma promoters in vivo and has transcriptional repressor activity that is reduced by Hay-Wells syndrome-derived mutations
    • Westfall MD, Mays DJ, Sniezek JC, Pietenpol JA (2003) The Delta Np63 alpha phosphoprotein binds the p21 and 14-3-3 sigma promoters in vivo and has transcriptional repressor activity that is reduced by Hay-Wells syndrome-derived mutations. Mol Cell Biol 23: 2264-2276.
    • (2003) Mol Cell Biol , vol.23 , pp. 2264-2276
    • Westfall, M.D.1    Mays, D.J.2    Sniezek, J.C.3    Pietenpol, J.A.4
  • 26
    • 46949086501 scopus 로고    scopus 로고
    • A chromatin immunoprecipitation screen in mouse keratinocytes reveals Runx1 as a direct transcriptional target of DeltaNp63
    • Ortt K, Raveh E, Gat U, Sinha S (2008) A chromatin immunoprecipitation screen in mouse keratinocytes reveals Runx1 as a direct transcriptional target of DeltaNp63. J Cell Biochem 104: 1204-1219.
    • (2008) J Cell Biochem , vol.104 , pp. 1204-1219
    • Ortt, K.1    Raveh, E.2    Gat, U.3    Sinha, S.4
  • 29
    • 16844386318 scopus 로고    scopus 로고
    • IGFBP-3 is a direct target of transcriptional regulation by DeltaNp63alpha in squamous epithelium
    • Barbieri CE, Perez CA, Johnson KN, Ely KA, Billheimer D, et al. (2005) IGFBP-3 is a direct target of transcriptional regulation by DeltaNp63alpha in squamous epithelium. Cancer Res 65: 2314-2320.
    • (2005) Cancer Res , vol.65 , pp. 2314-2320
    • Barbieri, C.E.1    Perez, C.A.2    Johnson, K.N.3    Ely, K.A.4    Billheimer, D.5
  • 30
    • 33744796255 scopus 로고    scopus 로고
    • p63 regulates an adhesion programme and cell survival in epithelial cells
    • Carroll DK, Carroll JS, Leong CO, Cheng F, Brown M, et al. (2006) p63 regulates an adhesion programme and cell survival in epithelial cells. Nat Cell Biol 8: 551-561.
    • (2006) Nat Cell Biol , vol.8 , pp. 551-561
    • Carroll, D.K.1    Carroll, J.S.2    Leong, C.O.3    Cheng, F.4    Brown, M.5
  • 31
    • 0024315871 scopus 로고
    • Fatty acid synthase, a proficient multifunctional enzyme
    • Wakil SJ (1989) Fatty acid synthase, a proficient multifunctional enzyme. Biochemistry 28: 4523-4530.
    • (1989) Biochemistry , vol.28 , pp. 4523-4530
    • Wakil, S.J.1
  • 32
    • 33645707835 scopus 로고    scopus 로고
    • The fatty acid synthase gene is a conserved p53 family target from worm to human
    • D'Erchia AM, Tullo A, Lefkimmiatis K, Saccone C, Sbisa E (2006) The fatty acid synthase gene is a conserved p53 family target from worm to human. Cell Cycle 5: 750-758.
    • (2006) Cell Cycle , vol.5 , pp. 750-758
    • D'Erchia, A.M.1    Tullo, A.2    Lefkimmiatis, K.3    Saccone, C.4    Sbisa, E.5
  • 33
    • 10844295905 scopus 로고    scopus 로고
    • Androgen-induced differentiation and tumorigenicity of human prostate epithelial cells
    • Berger R, Febbo PG, Majumder PK, Zhao JJ, Mukherjee S, et al. (2004) Androgen-induced differentiation and tumorigenicity of human prostate epithelial cells. Cancer Res 64: 8867-8875.
    • (2004) Cancer Res , vol.64 , pp. 8867-8875
    • Berger, R.1    Febbo, P.G.2    Majumder, P.K.3    Zhao, J.J.4    Mukherjee, S.5
  • 34
    • 67650015122 scopus 로고
    • The incorporation of acetate-1-C14 into cholesterol and fatty acids by surviving tissues of normal and scorbutic guinea pigs
    • Bolker HI, Fishman S, Heard RD, O'Donnell VJ, Webb JL, et al. (1956) The incorporation of acetate-1-C14 into cholesterol and fatty acids by surviving tissues of normal and scorbutic guinea pigs. J Exp Med 103: 199-205.
    • (1956) J Exp Med , vol.103 , pp. 199-205
    • Bolker, H.I.1    Fishman, S.2    Heard, R.D.3    O'Donnell, V.J.4    Webb, J.L.5
  • 35
    • 33845261493 scopus 로고
    • A rapid method of total lipid extraction and purification
    • Bligh EG, Dyer WJ (1959) A rapid method of total lipid extraction and purification. Can J Biochem Physiol 37: 911-917.
    • (1959) Can J Biochem Physiol , vol.37 , pp. 911-917
    • Bligh, E.G.1    Dyer, W.J.2
  • 36
    • 34547095764 scopus 로고    scopus 로고
    • Papillary carcinoma of the thyroid: Low expression of NCAM (CD56) is associated with downregulation of VEGF-D production by tumour cells
    • Scarpino S, Di Napoli A, Melotti F, Talerico C, Cancrini A, et al. (2007) Papillary carcinoma of the thyroid: low expression of NCAM (CD56) is associated with downregulation of VEGF-D production by tumour cells. J Pathol 212: 411-419.
    • (2007) J Pathol , vol.212 , pp. 411-419
    • Scarpino, S.1    Di Napoli, A.2    Melotti, F.3    Talerico, C.4    Cancrini, A.5
  • 37
    • 19944374798 scopus 로고    scopus 로고
    • Positive feedback regulation between AKT activation and fatty acid synthase expression in ovarian carcinoma cells
    • Wang HQ, Altomare DA, Skele KL, Poulikakos PI, Kuhajda FP, et al. (2005) Positive feedback regulation between AKT activation and fatty acid synthase expression in ovarian carcinoma cells. Oncogene 24: 3574-3582.
    • (2005) Oncogene , vol.24 , pp. 3574-3582
    • Wang, H.Q.1    Altomare, D.A.2    Skele, K.L.3    Poulikakos, P.I.4    Kuhajda, F.P.5
  • 38
    • 0036385719 scopus 로고    scopus 로고
    • Activation of fatty acid synthesis during neoplastic transformation: Role of mitogen-activated protein kinase and phosphatidylinositol 3-kinase
    • Yang YA, Han WF, Morin PJ, Chrest FJ, Pizer ES (2002) Activation of fatty acid synthesis during neoplastic transformation: role of mitogen-activated protein kinase and phosphatidylinositol 3-kinase. Exp Cell Res 279: 80-90.
    • (2002) Exp Cell Res , vol.279 , pp. 80-90
    • Yang, Y.A.1    Han, W.F.2    Morin, P.J.3    Chrest, F.J.4    Pizer, E.S.5
  • 39
    • 0036469122 scopus 로고    scopus 로고
    • Role of the phosphatidylinositol 3′-kinase/PTEN/Akt kinase pathway in the overexpression of fatty acid synthase in LNCaP prostate cancer cells
    • Van de Sande T, De Schrijver E, Heyns W, Verhoeven G, Swinnen JV (2002) Role of the phosphatidylinositol 3′-kinase/PTEN/Akt kinase pathway in the overexpression of fatty acid synthase in LNCaP prostate cancer cells. Cancer Res 62: 642-646.
    • (2002) Cancer Res , vol.62 , pp. 642-646
    • Van de Sande, T.1    De Schrijver, E.2    Heyns, W.3    Verhoeven, G.4    Swinnen, J.V.5
  • 40
    • 26244464326 scopus 로고    scopus 로고
    • PKB/Akt induces transcription of enzymes involved in cholesterol and fatty acid biosynthesis via activation of SREBP
    • Porstmann T, Griffiths B, Chung YL, Delpuech O, Griffiths JR, et al. (2005) PKB/Akt induces transcription of enzymes involved in cholesterol and fatty acid biosynthesis via activation of SREBP. Oncogene 24: 6465-6481.
    • (2005) Oncogene , vol.24 , pp. 6465-6481
    • Porstmann, T.1    Griffiths, B.2    Chung, Y.L.3    Delpuech, O.4    Griffiths, J.R.5
  • 41
    • 0942301281 scopus 로고    scopus 로고
    • p63 is the molecular switch for initiation of an epithelial stratification program
    • Koster MI, Kim S, Mills AA, DeMayo FJ, Roop DR (2004) p63 is the molecular switch for initiation of an epithelial stratification program. Genes Dev 18: 126-131.
    • (2004) Genes Dev , vol.18 , pp. 126-131
    • Koster, M.I.1    Kim, S.2    Mills, A.A.3    DeMayo, F.J.4    Roop, D.R.5
  • 42
    • 0037637624 scopus 로고    scopus 로고
    • Fatty acid synthesis is essential in embryonic development: Fatty acid synthase null mutants and most of the heterozygotes die in utero
    • Chirala SS, Chang H, Matzuk M, Abu-Elheiga L, Mao J, et al. (2003) Fatty acid synthesis is essential in embryonic development: fatty acid synthase null mutants and most of the heterozygotes die in utero. Proc Natl Acad Sci U S A 100: 6358-6363.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 6358-6363
    • Chirala, S.S.1    Chang, H.2    Matzuk, M.3    Abu-Elheiga, L.4    Mao, J.5
  • 43
    • 20144389083 scopus 로고    scopus 로고
    • Fatty acid synthase (FAS) is a marker of increased risk of recurrence in lung carcinoma
    • Visca P, Sebastiani V, Botti C, Diodoro MG, Lasagni RP, et al. (2004) Fatty acid synthase (FAS) is a marker of increased risk of recurrence in lung carcinoma. Anticancer Res 24: 4169-4173.
    • (2004) Anticancer Res , vol.24 , pp. 4169-4173
    • Visca, P.1    Sebastiani, V.2    Botti, C.3    Diodoro, M.G.4    Lasagni, R.P.5
  • 44
    • 0038176163 scopus 로고    scopus 로고
    • Expression of fatty acid synthase as a prognostic indicator in soft tissue sarcomas
    • Takahiro T, Shinichi K, Toshimitsu S (2003) Expression of fatty acid synthase as a prognostic indicator in soft tissue sarcomas. Clin Cancer Res 9: 2204-2212.
    • (2003) Clin Cancer Res , vol.9 , pp. 2204-2212
    • Takahiro, T.1    Shinichi, K.2    Toshimitsu, S.3
  • 45
    • 33645114908 scopus 로고    scopus 로고
    • Fatty acid synthase gene overexpression and copy number gain in prostate adenocarcinoma
    • Shah US, Dhir R, Gollin SM, Chandran UR, Lewis D, et al. (2006) Fatty acid synthase gene overexpression and copy number gain in prostate adenocarcinoma. Hum Pathol 37: 401-409.
    • (2006) Hum Pathol , vol.37 , pp. 401-409
    • Shah, U.S.1    Dhir, R.2    Gollin, S.M.3    Chandran, U.R.4    Lewis, D.5
  • 46
    • 33745698747 scopus 로고    scopus 로고
    • Gastrointestinal stromal tumours overexpress fatty acid synthase
    • Rossi S, Ou W, Tang D, Bhattacharya N, Dei Tos AP, et al. (2006) Gastrointestinal stromal tumours overexpress fatty acid synthase. J Pathol 209: 369-375.
    • (2006) J Pathol , vol.209 , pp. 369-375
    • Rossi, S.1    Ou, W.2    Tang, D.3    Bhattacharya, N.4    Dei Tos, A.P.5
  • 47
    • 0042429210 scopus 로고    scopus 로고
    • Fatty acid synthase expression defines distinct molecular signatures in prostate cancer
    • Rossi S, Graner E, Febbo P, Weinstein L, Bhattacharya N, et al. (2003) Fatty acid synthase expression defines distinct molecular signatures in prostate cancer. Mol Cancer Res 1: 707-715.
    • (2003) Mol Cancer Res , vol.1 , pp. 707-715
    • Rossi, S.1    Graner, E.2    Febbo, P.3    Weinstein, L.4    Bhattacharya, N.5
  • 48
    • 34748912615 scopus 로고    scopus 로고
    • Fatty acid synthase and the lipogenic phenotype in cancer pathogenesis
    • Menendez JA, Lupu R (2007) Fatty acid synthase and the lipogenic phenotype in cancer pathogenesis. Nat Rev Cancer 7: 763-777.
    • (2007) Nat Rev Cancer , vol.7 , pp. 763-777
    • Menendez, J.A.1    Lupu, R.2
  • 49
    • 0031007392 scopus 로고    scopus 로고
    • Increased expression of fatty acid synthase (OA-519) in ovarian neoplasms predicts shorter survival
    • Gansler TS, Hardman W 3rd, Hunt DA, Schaffel S, Hennigar RA (1997) Increased expression of fatty acid synthase (OA-519) in ovarian neoplasms predicts shorter survival. Hum Pathol 28: 686-692.
    • (1997) Hum Pathol , vol.28 , pp. 686-692
    • Gansler, T.S.1    Hardman 3rd, W.2    Hunt, D.A.3    Schaffel, S.4    Hennigar, R.A.5
  • 50
    • 2542478967 scopus 로고    scopus 로고
    • Fatty acid synthase is required for the proliferation of human oral squamous carcinoma cells
    • Agostini M, Silva SD, Zecchin KG, Coletta RD, Jorge J, et al. (2004) Fatty acid synthase is required for the proliferation of human oral squamous carcinoma cells. Oral Oncol 40: 728-735.
    • (2004) Oral Oncol , vol.40 , pp. 728-735
    • Agostini, M.1    Silva, S.D.2    Zecchin, K.G.3    Coletta, R.D.4    Jorge, J.5
  • 51
    • 0032532655 scopus 로고    scopus 로고
    • Pharmacological inhibitors of mammalian fatty acid synthase suppress DNA replication and induce apoptosis in tumor cell lines
    • Pizer ES, Chrest FJ, DiGiuseppe JA, Han WF (1998) Pharmacological inhibitors of mammalian fatty acid synthase suppress DNA replication and induce apoptosis in tumor cell lines. Cancer Res 58: 4611-4615.
    • (1998) Cancer Res , vol.58 , pp. 4611-4615
    • Pizer, E.S.1    Chrest, F.J.2    DiGiuseppe, J.A.3    Han, W.F.4
  • 52
    • 0035866378 scopus 로고    scopus 로고
    • Pharmacological inhibition of fatty acid synthase activity produces both cytostatic and cytotoxic effects modulated by p53
    • Li JN, Gorospe M, Chrest FJ, Kumaravel TS, Evans MK, et al. (2001) Pharmacological inhibition of fatty acid synthase activity produces both cytostatic and cytotoxic effects modulated by p53. Cancer Res 61: 1493-1499.
    • (2001) Cancer Res , vol.61 , pp. 1493-1499
    • Li, J.N.1    Gorospe, M.2    Chrest, F.J.3    Kumaravel, T.S.4    Evans, M.K.5
  • 54
    • 1542720382 scopus 로고    scopus 로고
    • Orlistat is a novel inhibitor of fatty acid synthase with antitumor activity
    • Kridel SJ, Axelrod F, Rozenkrantz N, Smith JW (2004) Orlistat is a novel inhibitor of fatty acid synthase with antitumor activity. Cancer Res 64: 2070-2075.
    • (2004) Cancer Res , vol.64 , pp. 2070-2075
    • Kridel, S.J.1    Axelrod, F.2    Rozenkrantz, N.3    Smith, J.W.4
  • 55
    • 0031427126 scopus 로고    scopus 로고
    • Apoptosis of androgen-independent prostate cell line induced by inhibition of fatty acid synthesis
    • Furuya Y, Akimoto S, Yasuda K, Ito H (1997) Apoptosis of androgen-independent prostate cell line induced by inhibition of fatty acid synthesis. Anticancer Res 17: 4589-4593.
    • (1997) Anticancer Res , vol.17 , pp. 4589-4593
    • Furuya, Y.1    Akimoto, S.2    Yasuda, K.3    Ito, H.4
  • 56
    • 57349175482 scopus 로고    scopus 로고
    • Fatty acid synthase inhibition with Orlistat promotes apoptosis and reduces cell growth and lymph node metastasis in a mouse melanoma model
    • Carvalho MA, Zecchin KG, Seguin F, Bastos DC, Agostini M, et al. (2008) Fatty acid synthase inhibition with Orlistat promotes apoptosis and reduces cell growth and lymph node metastasis in a mouse melanoma model. Int J Cancer 123: 2557-2565.
    • (2008) Int J Cancer , vol.123 , pp. 2557-2565
    • Carvalho, M.A.1    Zecchin, K.G.2    Seguin, F.3    Bastos, D.C.4    Agostini, M.5
  • 58
    • 38749092106 scopus 로고    scopus 로고
    • p51/p63 Inhibits ultraviolet B-induced apoptosis via Akt activation
    • Ogawa E, Okuyama R, Ikawa S, Nagoshi H, Egawa T, et al. (2008) p51/p63 Inhibits ultraviolet B-induced apoptosis via Akt activation. Oncogene 27: 848-856.
    • (2008) Oncogene , vol.27 , pp. 848-856
    • Ogawa, E.1    Okuyama, R.2    Ikawa, S.3    Nagoshi, H.4    Egawa, T.5
  • 59
    • 19944398464 scopus 로고    scopus 로고
    • High-level expression of fatty acid synthase in human prostate cancer tissues is linked to activation and nuclear localization of Akt/ PKB
    • Van de Sande T, Roskams T, Lerut E, Joniau S, Van Poppel H, et al. (2005) High-level expression of fatty acid synthase in human prostate cancer tissues is linked to activation and nuclear localization of Akt/ PKB. J Pathol 206: 214-219.
    • (2005) J Pathol , vol.206 , pp. 214-219
    • Van de Sande, T.1    Roskams, T.2    Lerut, E.3    Joniau, S.4    Van Poppel, H.5
  • 60
    • 7244252915 scopus 로고    scopus 로고
    • Pharmacological inhibition of fatty acid synthase (FAS): A novel therapeutic approach for breast cancer chemoprevention through its ability to suppress Her-2/ neu (erbB-2) oncogene-induced malignant transformation
    • Menendez JA, Mehmi I, Verma VA, Teng PK, Lupu R (2004) Pharmacological inhibition of fatty acid synthase (FAS): a novel therapeutic approach for breast cancer chemoprevention through its ability to suppress Her-2/ neu (erbB-2) oncogene-induced malignant transformation. Mol Carcinog 41: 164-178.
    • (2004) Mol Carcinog , vol.41 , pp. 164-178
    • Menendez, J.A.1    Mehmi, I.2    Verma, V.A.3    Teng, P.K.4    Lupu, R.5
  • 61
    • 24044494924 scopus 로고    scopus 로고
    • FAS expression inversely correlates with PTEN level in prostate cancer and a PI 3-kinase inhibitor synergizes with FAS siRNA to induce apoptosis
    • Bandyopadhyay S, Pai SK, Watabe M, Gross SC, Hirota S, et al. (2005) FAS expression inversely correlates with PTEN level in prostate cancer and a PI 3-kinase inhibitor synergizes with FAS siRNA to induce apoptosis. Oncogene 24: 5389-5395.
    • (2005) Oncogene , vol.24 , pp. 5389-5395
    • Bandyopadhyay, S.1    Pai, S.K.2    Watabe, M.3    Gross, S.C.4    Hirota, S.5
  • 62
    • 11144348618 scopus 로고    scopus 로고
    • Overexpression and hyperactivity of breast cancer-associated fatty acid synthase (oncogenic antigen-519) is insensitive to normal arachidonic fatty acid-induced suppression in lipogenic tissues but it is selectively inhibited by tumoricidal alpha-linolenic and gamma-linolenic fatty acids: A novel mechanism by which dietary fat can alter mammary tumorigenesis
    • Menendez JA, Ropero S, Mehmi I, Atlas E, Colomer R, et al. (2004) Overexpression and hyperactivity of breast cancer-associated fatty acid synthase (oncogenic antigen-519) is insensitive to normal arachidonic fatty acid-induced suppression in lipogenic tissues but it is selectively inhibited by tumoricidal alpha-linolenic and gamma-linolenic fatty acids: a novel mechanism by which dietary fat can alter mammary tumorigenesis. Int J Oncol 24: 1369-1383.
    • (2004) Int J Oncol , vol.24 , pp. 1369-1383
    • Menendez, J.A.1    Ropero, S.2    Mehmi, I.3    Atlas, E.4    Colomer, R.5
  • 63
    • 0034718771 scopus 로고    scopus 로고
    • Stimulation of tumor-associated fatty acid synthase expression by growth factor activation of the sterol regulatory element-binding protein pathway
    • Swinnen JV, Heemers H, Deboel L, Foufelle F, Heyns W, et al. (2000) Stimulation of tumor-associated fatty acid synthase expression by growth factor activation of the sterol regulatory element-binding protein pathway. Oncogene 19: 5173-5181.
    • (2000) Oncogene , vol.19 , pp. 5173-5181
    • Swinnen, J.V.1    Heemers, H.2    Deboel, L.3    Foufelle, F.4    Heyns, W.5
  • 64
    • 0033963942 scopus 로고    scopus 로고
    • Overexpression of fatty acid synthase in SKBR3 breast cancer cell line is mediated via a transcriptional mechanism
    • Oskouian B (2000) Overexpression of fatty acid synthase in SKBR3 breast cancer cell line is mediated via a transcriptional mechanism. Cancer Lett 149: 43-51.
    • (2000) Cancer Lett , vol.149 , pp. 43-51
    • Oskouian, B.1


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