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Volumn 27, Issue 6, 2008, Pages 848-856

p51/p63 inhibits ultraviolet B-induced apoptosis via Akt activation

Author keywords

Apoptosis; Epidermis; p51 p63; p53; UV

Indexed keywords

AMIDE; ISOPROTEIN; PROTEIN KINASE B; PROTEIN P51; PROTEIN P63; SMALL INTERFERING RNA;

EID: 38749092106     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/sj.onc.1210682     Document Type: Article
Times cited : (19)

References (26)
  • 1
    • 0036156147 scopus 로고    scopus 로고
    • Retinoic acid inhibits downregulation of DeltaNp63alpha expression during terminal differentiation of human primary keratinocytes
    • Bamberger C, Pollet D, Schmale H. (2002). Retinoic acid inhibits downregulation of DeltaNp63alpha expression during terminal differentiation of human primary keratinocytes. J Invest Dermatol 118: 133-138.
    • (2002) J Invest Dermatol , vol.118 , pp. 133-138
    • Bamberger, C.1    Pollet, D.2    Schmale, H.3
  • 3
    • 0035448879 scopus 로고    scopus 로고
    • Growth retardation and increased apoptosis in mice with homozygous disruption of the Akt1 gene
    • Chen WS, Xu PZ, Gottlob K, Chen ML, Sokol K, Shiyanova T et al. (2001). Growth retardation and increased apoptosis in mice with homozygous disruption of the Akt1 gene. Genes Dev 15: 2203-2208.
    • (2001) Genes Dev , vol.15 , pp. 2203-2208
    • Chen, W.S.1    Xu, P.Z.2    Gottlob, K.3    Chen, M.L.4    Sokol, K.5    Shiyanova, T.6
  • 4
    • 30644457489 scopus 로고    scopus 로고
    • Expression of p53, p63, and p73 isoforms in squamous cell carcinoma and adenocarcinoma of esophagus
    • Epub ahead of print
    • Cui R, He J, Mei R, de Fromentel CC, Martel-Planche G, Taniere P et al. (2005). Expression of p53, p63, and p73 isoforms in squamous cell carcinoma and adenocarcinoma of esophagus. Biochem Biophys Res Commun: (Epub ahead of print).
    • (2005) Biochem Biophys Res Commun
    • Cui, R.1    He, J.2    Mei, R.3    de Fromentel, C.C.4    Martel-Planche, G.5    Taniere, P.6
  • 5
    • 0034743628 scopus 로고    scopus 로고
    • p63alpha and DeltaNp63alpha can induce cell cycle arrest and apoptosis and differentially regulate p53 target genes
    • Dohn M, Zhang S, Chen X. (2001). p63alpha and DeltaNp63alpha can induce cell cycle arrest and apoptosis and differentially regulate p53 target genes. Oncogene 20: 3193-3205.
    • (2001) Oncogene , vol.20 , pp. 3193-3205
    • Dohn, M.1    Zhang, S.2    Chen, X.3
  • 6
    • 27844497945 scopus 로고    scopus 로고
    • FOXO transcription factors at the interface between longevity and tumor suppression
    • Greer EL, Brunet A. (2005). FOXO transcription factors at the interface between longevity and tumor suppression. Oncogene 24: 7410-7425.
    • (2005) Oncogene , vol.24 , pp. 7410-7425
    • Greer, E.L.1    Brunet, A.2
  • 7
    • 0033595088 scopus 로고    scopus 로고
    • p53 protects against skin cancer induction by UV-B radiation
    • Jiang W, Ananthaswamy HN, Muller HK, Kripke ML. (1999). p53 protects against skin cancer induction by UV-B radiation. Oncogene 18: 4247-4253.
    • (1999) Oncogene , vol.18 , pp. 4247-4253
    • Jiang, W.1    Ananthaswamy, H.N.2    Muller, H.K.3    Kripke, M.L.4
  • 8
    • 24344447780 scopus 로고    scopus 로고
    • p63 deficiency activates a program of cellular senescence and leads to accelerated aging
    • Keyes WM, Wu Y, Vogel H, Guo X, Lowe SW, Mills AA. (2005). p63 deficiency activates a program of cellular senescence and leads to accelerated aging. Genes Dev 19: 1986-1999.
    • (2005) Genes Dev , vol.19 , pp. 1986-1999
    • Keyes, W.M.1    Wu, Y.2    Vogel, H.3    Guo, X.4    Lowe, S.W.5    Mills, A.A.6
  • 9
    • 33646245191 scopus 로고    scopus 로고
    • Reactivation of developmentally expressed p63 isoforms predisposes to tumor development and progression
    • Koster MI, Lu SL, White LD, Wang XJ, Roop DR. (2006). Reactivation of developmentally expressed p63 isoforms predisposes to tumor development and progression. Cancer Res 66: 3981-3986.
    • (2006) Cancer Res , vol.66 , pp. 3981-3986
    • Koster, M.I.1    Lu, S.L.2    White, L.D.3    Wang, X.J.4    Roop, D.R.5
  • 10
    • 0031022619 scopus 로고    scopus 로고
    • Sunlightand skin cancer: Another link revealed
    • Kraemer KH. (1997). Sunlightand skin cancer: another link revealed. Proc Natl Acad Sci USA 94: 11-14.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 11-14
    • Kraemer, K.H.1
  • 11
  • 12
    • 30644474977 scopus 로고    scopus 로고
    • Mills AA. (2006). p63: oncogene or tumor suppressor? Curr Opin Genet Dev 16: 38-44.
    • Mills AA. (2006). p63: oncogene or tumor suppressor? Curr Opin Genet Dev 16: 38-44.
  • 13
    • 0033594491 scopus 로고    scopus 로고
    • p63 is a p53 homologue required for limb and epidermal morphogenesis
    • Mills AA, Zheng B, Wang XJ, Vogel H, Roop DR, Bradley A. (1999). p63 is a p53 homologue required for limb and epidermal morphogenesis. Nature 398: 708-713.
    • (1999) Nature , vol.398 , pp. 708-713
    • Mills, A.A.1    Zheng, B.2    Wang, X.J.3    Vogel, H.4    Roop, D.R.5    Bradley, A.6
  • 14
    • 11144356373 scopus 로고    scopus 로고
    • High commitment of embryonic keratinocytes to terminal differentiation through a Notch1-caspase 3 regulatory mechanism
    • Okuyama R, Nguyen BC, Talora C, Ogawa E, Tommasi di Vignano A, Lioumi M et al. (2004). High commitment of embryonic keratinocytes to terminal differentiation through a Notch1-caspase 3 regulatory mechanism. Dev Cell 6: 551-562.
    • (2004) Dev Cell , vol.6 , pp. 551-562
    • Okuyama, R.1    Nguyen, B.C.2    Talora, C.3    Ogawa, E.4    Tommasi di Vignano, A.5    Lioumi, M.6
  • 15
    • 34447125200 scopus 로고    scopus 로고
    • p53 homologue, p51/p63, maintains the immaturity of keratinocyte stem cells by inhibiting Notch1 activity
    • Okuyama R, Ogawa E, Nagoshi H, Yabuki M, Kurihara A, Terui T et al. (2007). p53 homologue, p51/p63, maintains the immaturity of keratinocyte stem cells by inhibiting Notch1 activity. Oncogene 26: 4478-4488.
    • (2007) Oncogene , vol.26 , pp. 4478-4488
    • Okuyama, R.1    Ogawa, E.2    Nagoshi, H.3    Yabuki, M.4    Kurihara, A.5    Terui, T.6
  • 16
    • 0031852337 scopus 로고    scopus 로고
    • Cloning and functional analysis of human p51, which structurally and functionally resembles p53
    • Osada M, Ohba M, Kawahara C, Ishioka C, Kanamaru R, Katoh I et al. (1998). Cloning and functional analysis of human p51, which structurally and functionally resembles p53. Nat Med 4: 839-843.
    • (1998) Nat Med , vol.4 , pp. 839-843
    • Osada, M.1    Ohba, M.2    Kawahara, C.3    Ishioka, C.4    Kanamaru, R.5    Katoh, I.6
  • 17
    • 27144448738 scopus 로고    scopus 로고
    • A p38-dependent pathway regulates DeltaNp63 DNA binding to p53-dependent promoters in UV-induced apoptosis of keratinocytes
    • Papoutsaki M, Moretti F, Lanza M, Marinari B, Sartorelli V, Guerrini L et al. (2005). A p38-dependent pathway regulates DeltaNp63 DNA binding to p53-dependent promoters in UV-induced apoptosis of keratinocytes. Oncogene 24: 6970-6975.
    • (2005) Oncogene , vol.24 , pp. 6970-6975
    • Papoutsaki, M.1    Moretti, F.2    Lanza, M.3    Marinari, B.4    Sartorelli, V.5    Guerrini, L.6
  • 20
    • 33744948789 scopus 로고    scopus 로고
    • AKT1 provides an essential survival signal required for differentiation and stratification on primary human keratinocytes
    • Thrash BR, Menges CW, Pierce RH, McCance DJ. (2006). AKT1 provides an essential survival signal required for differentiation and stratification on primary human keratinocytes. J Biol Chem 281: 12155-12162.
    • (2006) J Biol Chem , vol.281 , pp. 12155-12162
    • Thrash, B.R.1    Menges, C.W.2    Pierce, R.H.3    McCance, D.J.4
  • 21
    • 0042337365 scopus 로고    scopus 로고
    • Differential regulation of p63 and p73 expression
    • Waltermann A, Kartasheva NN, Dobbelstein M. (2003). Differential regulation of p63 and p73 expression. Oncogene 22: 5686-5693.
    • (2003) Oncogene , vol.22 , pp. 5686-5693
    • Waltermann, A.1    Kartasheva, N.N.2    Dobbelstein, M.3
  • 22
    • 0242580735 scopus 로고    scopus 로고
    • Epidermal growth factor receptor-dependent, NF-kappaB-independent activation of the phosphatidylinositol 3-kinase/Akt pathway inhibits ultraviolet irradiation-induced caspases-3, -8, and -9 in human keratinocytes
    • Wang HQ, Quan T, He T, Franke TF, Voorhees JJ, Fisher GJ. (2003). Epidermal growth factor receptor-dependent, NF-kappaB-independent activation of the phosphatidylinositol 3-kinase/Akt pathway inhibits ultraviolet irradiation-induced caspases-3, -8, and -9 in human keratinocytes. J Biol Chem 278: 45737-45745.
    • (2003) J Biol Chem , vol.278 , pp. 45737-45745
    • Wang, H.Q.1    Quan, T.2    He, T.3    Franke, T.F.4    Voorhees, J.J.5    Fisher, G.J.6
  • 23
    • 25144495237 scopus 로고    scopus 로고
    • Ultraviolet radiation induces phosphorylation and ubiquitin-mediated degradation of DeltaNp63alpha
    • Westfall MD, Joyner AS, Barbieri CE, Livingstone M, Pietenpol JA. (2005). Ultraviolet radiation induces phosphorylation and ubiquitin-mediated degradation of DeltaNp63alpha. Cell Cycle 4: 710-716.
    • (2005) Cell Cycle , vol.4 , pp. 710-716
    • Westfall, M.D.1    Joyner, A.S.2    Barbieri, C.E.3    Livingstone, M.4    Pietenpol, J.A.5
  • 24
    • 0032161624 scopus 로고    scopus 로고
    • p63, a p53 homolog at3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities
    • Yang A, Kaghad M, Wang Y, Gillett E, Fleming MD, Dotsch V et al. (1998). p63, a p53 homolog at3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities. Mol Cell 2: 305-316.
    • (1998) Mol Cell , vol.2 , pp. 305-316
    • Yang, A.1    Kaghad, M.2    Wang, Y.3    Gillett, E.4    Fleming, M.D.5    Dotsch, V.6
  • 25
    • 0033594485 scopus 로고    scopus 로고
    • p63 is essential for regenerative proliferation in limb, craniofacial and epithelial development
    • Yang A, Schweitzer R, Sun D, Kaghad M, Walker N, Bronson RT et al. (1999). p63 is essential for regenerative proliferation in limb, craniofacial and epithelial development. Nature 398: 714-718.
    • (1999) Nature , vol.398 , pp. 714-718
    • Yang, A.1    Schweitzer, R.2    Sun, D.3    Kaghad, M.4    Walker, N.5    Bronson, R.T.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.