-
1
-
-
40949095655
-
Guide to receptors and channels (GRAC)
-
Third edition
-
Alexander SPH, Mathie A, Peters JA. Guide to receptors and channels (GRAC). Third edition. Br J Pharmacol 2008;153(Suppl 2):S1-S209
-
(2008)
Br J Pharmacol
, vol.153
, Issue.SUPPL. 2
-
-
Alexander, S.P.H.1
Mathie, A.2
Peters, J.A.3
-
2
-
-
36749020746
-
Potassium channel blockers and openers as CNS neurologic therapeutic agents
-
DOI 10.2174/157488907782411765
-
Judge SIV, Smith PJ, Stewart PE, Bever CT. Potassium channel blockers and openers as CNS neurologic therapeutic agents. Rec Patents CNS Drug Discov 2007;2:200-228 (Pubitemid 350200292)
-
(2007)
Recent Patents on CNS Drug Discovery
, vol.2
, Issue.3
, pp. 200-228
-
-
Judge, S.I.V.1
Smith, P.J.2
Stewart, P.E.3
Bever Jr., C.T.4
-
3
-
-
33646776060
-
v channels and effects of symptomatic treatment
-
DOI 10.1016/j.pharmthera.2005.10.006, PII S0163725805002287
-
Judge SIV, Bever CT Jr. Potassium channel blockers in multiple sclerosis: neuronal Kv channels and effects of symptomatic treatment. Pharmacol Ther 2006;111:224-259 (Pubitemid 43765538)
-
(2006)
Pharmacology and Therapeutics
, vol.111
, Issue.1
, pp. 224-259
-
-
Judge, S.I.V.1
Bever Jr., C.T.2
-
4
-
-
29844437655
-
LIII. Nomenclature and molecular relationships of voltage-gated potassium channels
-
International Union of Pharmacology
-
Gutman GA, Chandy KG, Grissmer S, et al. International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels. Pharmacol Rev 2005;57:473-508
-
(2005)
Pharmacol Rev
, vol.57
, pp. 473-508
-
-
Gutman, G.A.1
Chandy, K.G.2
Grissmer, S.3
-
5
-
-
29844439979
-
LII. Nomenclature and molecular relationships of calcium-activated potassium channels
-
International Union of Pharmacology
-
Wei AD, Gutman GA, Aldrich R, et al. International Union of Pharmacology. LII. Nomenclature and molecular relationships of calcium-activated potassium channels. Pharmacol Rev 2005;57:463-472
-
(2005)
Pharmacol Rev
, vol.57
, pp. 463-472
-
-
Wei, A.D.1
Gutman, G.A.2
Aldrich, R.3
-
6
-
-
29844450489
-
LIV. Nomenclature and molecular relationships of inwardly rectifying potassium channels
-
International Union of Pharmacology
-
Kubo Y, Adelman JP, Clapham DE, Jan LY. International Union of Pharmacology. LIV. Nomenclature and molecular relationships of inwardly rectifying potassium channels. Pharmacol Rev 2005;57:509-526
-
(2005)
Pharmacol Rev
, vol.57
, pp. 509-526
-
-
Kubo, Y.1
Adelman, J.P.2
Clapham, D.E.3
Jan, L.Y.4
-
7
-
-
29844435013
-
LV. Nomenclature and molecular relationships of two-P potassium channels
-
International Union of Pharmacology
-
Goldstein SAN, Bayliss DA, Kim D, et al. International Union of Pharmacology. LV. Nomenclature and molecular relationships of two-P potassium channels. Pharmacol Rev 2005;57:527-540
-
(2005)
Pharmacol Rev
, vol.57
, pp. 527-540
-
-
Goldstein, S.A.N.1
Bayliss, D.A.2
Kim, D.3
-
8
-
-
0021086270
-
+ channels in cardiac muscle
-
Noma A. ATP-regulated K+ channels in cardiac muscle. Nature 1983;305(5930):147-148 (Pubitemid 14235671)
-
(1983)
Nature
, vol.305
, Issue.5930
, pp. 147-148
-
-
Noma, A.1
-
9
-
-
0021892605
-
Properties of adenosine-triphosphate-regulated potassium channels
-
Lond
-
Kakei M, Noma A, Shibasaki T. Properties of adenosine-triphosphate- regulated potassium channels. J Physiol (Lond) 1985;363:441-462
-
(1985)
J Physiol
, vol.363
, pp. 441-462
-
-
Kakei, M.1
Noma, A.2
Shibasaki, T.3
-
10
-
-
0021892605
-
Properties of adenosine-triphosphate-regulated potassium channels in guinea-pig ventricular cells
-
Noma A, Shibasaki T. Membrane current through adenosine-triphosphate- regulated potassium channels in guinea-pig ventricular cells. J Physiol (Lond) 1985;363:441-462 (Pubitemid 15000318)
-
(1985)
Journal of Physiology
, vol.VOL. 363
, pp. 441-462
-
-
Kakei, M.1
Noma, A.2
Shibasaki, T.3
-
11
-
-
0021187646
-
+ channels in pancreatic B-cells
-
Cook DL, Hales CN. Intracellular ATP directly blocks K+ channels in pancreatic beta-cells. Nature 1984;311(5983):271-273 (Pubitemid 14071146)
-
(1984)
Nature
, vol.311
, Issue.5983
, pp. 271-273
-
-
Cook, D.L.1
Hales, C.N.2
-
12
-
-
0021741559
-
Glucose induces closure of single potassium channels in isolated rat pancreatic β-cells
-
DOI 10.1038/312446a0
-
Ashcroft FM, Harrison DE, Ashcroft SJ. Glucose induces closure of single potassium channels in isolated rat pancreatic beta-cells. Nature 1984;312(5993):446-448 (Pubitemid 15217837)
-
(1984)
Nature
, vol.312
, Issue.5993
, pp. 446-448
-
-
Ashcroft, F.M.1
Harrison, D.E.2
Ashcroft, S.J.H.3
-
13
-
-
0022375444
-
+-channels in pancreatic β-cells are regulated by intracellular ATP
-
DOI 10.1007/BF00595682
-
Rorsman P, Trube G. Glucose dependent K+-channels in pancreatic beta-cells are regulated by intracellular ATP. Pflügers Arch 1985;405(4):305-309 (Pubitemid 16202499)
-
(1985)
Pflugers Archiv European Journal of Physiology
, vol.405
, Issue.4
, pp. 305-309
-
-
Rorsman, P.1
Trube, G.2
-
14
-
-
0023759316
-
Adenosine-5'-triphosphate-sensitive ion channels in neonatal rat cultured central neurones
-
DOI 10.1007/BF00582512
-
Ashford ML, Sturgess NC, Trout NJ, et al. Adenosine-5′- triphosphate-sendsitive ion channels in neonatal rat cultured central neurones. Pflügers Arch 1988;412(3):297-304 (Pubitemid 18196384)
-
(1988)
Pflugers Archiv European Journal of Physiology
, vol.412
, Issue.3
, pp. 297-304
-
-
Ashford, M.L.J.1
Sturgess, N.C.2
Trout, N.J.3
Gardner, N.J.4
Hales, C.N.5
-
15
-
-
0025164846
-
+ channels
-
Amoroso S, Schmid-Antomarchi H, Fosset M, Lazdunski M. Glucose, sulfonylureas, and neurotransmitter release: role of ATP-sensitive K+ channels. Science 1990;247(4944):852-854 (Pubitemid 20078565)
-
(1990)
Science
, vol.247
, Issue.4944
, pp. 852-854
-
-
Amoroso, S.1
Schmid-Antomarchi, H.2
Fosset, M.3
Lazdunski, M.4
-
16
-
-
15744370602
-
ATP channel openers
-
DOI 10.1016/j.yjmcc.2004.11.030, PII S0022282804003700
-
Moreau C, Prost AL, Dérand R, Vivaudou M. SUR, ABC proteins targeted by KATP channel openers. J Mol Cell Cardiol 2005;38(6):951-963 (Pubitemid 40725943)
-
(2005)
Journal of Molecular and Cellular Cardiology
, vol.38
, Issue.6
, pp. 951-963
-
-
Moreau, C.1
Prost, A.-L.2
Derand, R.3
Vivaudou, M.4
-
17
-
-
0021840516
-
The sulphonylurea receptor may be an ATP-sensitive potassium channel
-
Sturgess NC, Ashford ML, Cook DL, Hales CN. The suphonylurea receptor may be an ATP-sensitive potassium channels. Lancet 1985;2(8453):474-475 (Pubitemid 15013927)
-
(1985)
Lancet
, vol.2
, Issue.8453
, pp. 474
-
-
Sturgess, N.C.1
Ashford, M.L.J.2
Cook, D.L.3
Hales, C.N.4
-
18
-
-
0023772326
-
Effects of sulphonylureas and diazoxide on insulin secretion and nucleotide-sensitive channels in an insulin-secreting cell line
-
Sturgess NC, Kozlowski RZ, Carrington CA, et al. Effects of sulphonylureas and diazoxide on insulin secretion and nucleotide-sensitive channels in an insulin-secreting cell line. Br J Pharmacol 1988;95(1):83-94 (Pubitemid 18225202)
-
(1988)
British Journal of Pharmacology
, vol.95
, Issue.1
, pp. 83-94
-
-
Sturgess, N.C.1
Kozlowski, R.Z.2
Carrington, C.A.3
Hales, C.N.4
Ashford, M.L.J.5
-
20
-
-
0023551949
-
+ channels in an insulin-secreting cell line
-
Dunne MJ, Illot MC, Peterson OH. Interaction of diazoxide, tolbutamide and ATP4- on nucleotide-dependent K+ channels in an insulin-secreting cell line. J Membr Biol 1987;99(3):215-224 (Pubitemid 18046040)
-
(1987)
Journal of Membrane Biology
, vol.99
, Issue.3
, pp. 215-224
-
-
Dunne, M.J.1
Illot, M.C.2
Petersen, O.H.3
-
21
-
-
56549101329
-
Iptakalim protects against hypoxic brain injury through multiple pathways associated with ATP-sensitive potassium channels
-
Zhu HL, Luo WQ, Wang H. Iptakalim protects against hypoxic brain injury through multiple pathways associated with ATP-sensitive potassium channels. Neuroscience 2008;157:884-894
-
(2008)
Neuroscience
, vol.157
, pp. 884-894
-
-
Zhu, H.L.1
Luo, W.Q.2
Wang, H.3
-
22
-
-
40749157584
-
Pial microvascular responses to transient bilateral common carotid artery occlusion: Effects of hypertonic glycerol
-
DOI 10.1159/000109818
-
Lapi D, Marchiafava PL, Colantuoni A. Pial microvascular responses to transienet bilateral common carotid artery occlusion: effects of hypertonic glycerol. J Vasc Res 2008;45(2):89-102 (Pubitemid 351651294)
-
(2008)
Journal of Vascular Research
, vol.45
, Issue.2
, pp. 89-102
-
-
Lapi, D.1
Marchiafava, P.L.2
Colantuoni, A.3
-
23
-
-
42049097234
-
KATP channel openers facilitate glutamate uptake by GluTs in rat primary cultured astrocytes
-
Sun XL, Zeng XZ, Zhou F, et al. KATP channel openers facilitate glutamate uptake by GluTs in rat primary cultured astrocytes. Neuropharmacology 2008;33(6):1336-1342
-
(2008)
Neuropharmacology
, vol.33
, Issue.6
, pp. 1336-1342
-
-
Sun, X.L.1
Zeng, X.Z.2
Zhou, F.3
-
24
-
-
12344257722
-
Activation of ATP-sensitive potassium channels prevents the cleavage of cytosolic μ-calpain and abrogates the elevation of nuclear c-Fos and c-Jun expressions after hypoxic-ischemia in neonatal rat brain
-
DOI 10.1016/j.molbrainres.2004.09.020, PII S0169328X04004620
-
Jiang KW, Yu ZS, Shui QX, Xia ZZ. Activation of ATP-sensitive potassium channels prevents the cleavage of cytosolic μ-ccalpain and abrogates the elevation of nuclear c-Fos and c-Jun expressions after hypoxic-ischemia in neonatal rat brain. Mol Brain Res 2005;133(1):87-94 (Pubitemid 40127493)
-
(2005)
Molecular Brain Research
, vol.133
, Issue.1
, pp. 87-94
-
-
Jiang, K.-W.1
Yu, Z.-S.2
Shui, Q.-X.3
Xia, Z.-Z.4
-
25
-
-
1642499307
-
Hypothermic Preconditioning Increases Survival of Purkinje Neurons in Rat Cerebellar Slices after an in Vitro Simulated Ischemia
-
DOI 10.1097/00000542-200402000-00023
-
Yuan HB, Huang Y, Zheng S, Zuo Z. Hypothermic preconditioning increases survival of Purkinje neurons in rat cerebellar slices after an in vitro simulated ischemia. Anesthesiology 2004;100(2):331-337 (Pubitemid 38133701)
-
(2004)
Anesthesiology
, vol.100
, Issue.2
, pp. 331-337
-
-
Yuan, H.-B.1
Huang, Y.2
Zheng, S.3
Zuo, Z.4
-
26
-
-
0344393080
-
Diazoxide induces delayed pre-conditioning in cultured rat cortical neurons
-
DOI 10.1046/j.1471-4159.2003.02072.x
-
Kis BK, Rajapakse NC, Snipes JA, et al. Diazoxide induces delayed pre-conditioning in cultures rat cortical neurons. J Neurochem 2003;87(4):969-980 (Pubitemid 37444572)
-
(2003)
Journal of Neurochemistry
, vol.87
, Issue.4
, pp. 969-980
-
-
Kis, B.1
Rajapakse, N.C.2
Snipes, J.A.3
Nagy, K.4
Horiguchi, T.5
Busija, D.W.6
-
27
-
-
0032865345
-
Neuroprotection by ATP-dependent potassium channels in rat neocortical brain slices during hypoxia
-
DOI 10.1016/S0304-3940(99)00603-5, PII S0304394099006035
-
Garcia De Arriba S, Franke H, Pissarek M, et al. Neuroprotection by ATP-dependent potassium channels in rat neocortical brain slices during hypoxia. Neurosci Let 1999;273(1):13-16 (Pubitemid 29415691)
-
(1999)
Neuroscience Letters
, vol.273
, Issue.1
, pp. 13-16
-
-
Garcia De Arriba, S.1
Franke, H.2
Pissarek, M.3
Nieber, K.4
Illes, P.5
-
28
-
-
0030894345
-
Increased hypotoxic tolerance by chemical inhibition of oxidative phosphorylation: 'Chemical preconditioning'
-
Riepe MW, Esclaire F, Kasischke K, et al. Increased hypotoxic tolerance by chemical inhibition of oxidative phosphorylation: 'chemical preconditioning'. J Cereb Blood Flow Metab 1997;17(3):257-264
-
(1997)
J Cereb Blood Flow Metab
, vol.17
, Issue.3
, pp. 257-264
-
-
Riepe, M.W.1
Esclaire, F.2
Kasischke, K.3
-
29
-
-
39449132749
-
+ channels regulate NMDAR activity in the cortex of the anoxic western painted turtle
-
DOI 10.1113/jphysiol.2007.142380
-
Pamenter ME, Shin D SH, Cooray M, Buck LT. Mitochondrial ATP-sensitive K+ channels regulate NMDAR activity in the cortex of the anoxic western painted turtle. J Physiol (Lond) 2008;586(4):1043-1058 (Pubitemid 351267345)
-
(2008)
Journal of Physiology
, vol.586
, Issue.4
, pp. 1043-1058
-
-
Pamenter, M.E.1
Shin, D.S.-H.2
Cooray, M.3
Buck, L.T.4
-
30
-
-
36348935147
-
ATP channel during induction of ischemic preconditioning in the rat hippocampus
-
DOI 10.1016/j.brainres.2007.09.073, PII S0006899307023220
-
Raval AP, Dave KR, DeFrazio RA, Perez-Pinzon MA. EpsilonPKC phosphorylates the mitochondrial K+ATP channel during induction of ischemic preconditioning in the rat hippocampus. Brain Res 2007;1184:345-353 (Pubitemid 350160588)
-
(2007)
Brain Research
, vol.1184
, Issue.1
, pp. 345-353
-
-
Raval, A.P.1
Dave, K.R.2
Defazio, R.A.3
Perez-Pinzon, M.A.4
-
31
-
-
33646174443
-
Enhanced neuronal damage after ischemic insults in mice lacking Kir6.2-containing ATP-sensitive K+ channels
-
Sun HS, Feng ZP, Miki T, et al. Enhanced neuronal damage after ischemic insults in mice lacking Kir6.2-containing ATP-sensitive K+ channels. J Neurophyiol 2005;95(4):2590-2601
-
(2005)
J Neurophyiol
, vol.95
, Issue.4
, pp. 2590-2601
-
-
Sun, H.S.1
Feng, Z.P.2
Miki, T.3
-
32
-
-
23344454798
-
Nicorandil attenuates NF-κB activation, adhesion molecule expression, and cytokine production in patients with coronary artery bypass surgery
-
DOI 10.1097/01.shk.0000168874.83401.3f
-
Kawamura T, Kadosaki M, Nara N, et al. Nicorandil attenuates NF-κB activation, adhesion molecule expression, and cytokine production in patients with coronary artery bypass surgery. Shock 2005;24(2):103-108 (Pubitemid 41105505)
-
(2005)
Shock
, vol.24
, Issue.2
, pp. 103-108
-
-
Kawamura, T.1
Kadosaki, M.2
Nara, N.3
Wei, J.4
Endo, S.5
Inada, K.6
-
33
-
-
21244443050
-
Remote ischemic preconditioning of the recipient reduces myocardial ischemia-reperfusion injury of the denervated donor heart via a Katp channel-dependent mechanism
-
DOI 10.1097/01.TP.0000159137.76400.5D
-
Konstantinov IE, Cheung MM, Shimizu M, et al. Remote ischemic preconditioning of the recipient reduces myocardial ischemia-reperfusion injury of the denervated donor heart via a Katp channel-dependent mechanism. Transplantation 2005;79(12):1691-1695 (Pubitemid 40885266)
-
(2005)
Transplantation
, vol.79
, Issue.12
, pp. 1691-1695
-
-
Konstantinov, I.E.1
Li, J.2
Cheung, M.M.3
Shimizu, M.4
Stokoe, J.5
Kharbanda, R.K.6
Redington, A.N.7
-
34
-
-
4344683302
-
ATP channels
-
DOI 10.1016/j.brainres.2004.06.038, PII S0006899304010327
-
Kehl F, Payne RS, Toewer N, Schurr A. Seveflurane-induced preconditioning of rat brain in vitro and the role of KATP channels. Brain Res 2004;1021(1):76-81 (Pubitemid 39158659)
-
(2004)
Brain Research
, vol.1021
, Issue.1
, pp. 76-81
-
-
Kehl, F.1
Payne, R.S.2
Roewer, N.3
Schurr, A.4
-
35
-
-
4444277550
-
ATP channels and reduces ischaemic damage in rat hippocampus
-
DOI 10.1111/j.1471-4159.2004.02587.x
-
Bancila V, Nikonenko I, Dunant Y, et al. Zinc inhibits glutamate release via activation of pre-synaptic K channels and reduces ischaemic damage in rat hippocampus. J Neurochem 2004;90(5):1243-1250 (Pubitemid 39167357)
-
(2004)
Journal of Neurochemistry
, vol.90
, Issue.5
, pp. 1243-1250
-
-
Bancila, V.1
Nikonenko, I.2
Dunant, Y.3
Bloc, A.4
-
36
-
-
16644399096
-
Neuroprotective effect of KR-31378 via KATP channel opening against ischemic insult
-
Won R, Lim JY, Lee SY, et al. Neuroprotective effect of KR-31378 via KATP channel opening against ischemic insult. Biol Pharm Bull 200427(8):1285-1288
-
(2004)
Biol Pharm Bull
, vol.27
, Issue.8
, pp. 1285-1288
-
-
Won, R.1
Lim, J.Y.2
Lee, S.Y.3
-
37
-
-
3142780556
-
ATP channel activity in dorsal vagal neurons of juvenile rats in situ during metabolic disturbances
-
DOI 10.1016/j.brainres.2004.05.030, PII S0006899304007802
-
Raupach T, Ballanyi K. Intracellular pH and KATP channel activity in dorsal vagal neurons of juvenile rats in situ during metabolic disturbances. Brain Res 2004;1017(1-2):137-145 (Pubitemid 38917153)
-
(2004)
Brain Research
, vol.1017
, Issue.1-2
, pp. 137-145
-
-
Raupach, T.1
Ballanyi, K.2
-
38
-
-
3042815655
-
Adenosine A(1) receptor antagonist and mitochondrial ATP-sensitive potassium channel blocker attenuate the tolerance to focal cerebral ischemia in rats
-
Yoshida M, Nakakimura K, Cui YJ, et al. Adenosine A(1) receptor antagonist and mitochondrial ATP-sensitive potassium channel blocker attenuate the tolerance to focal cerebral ischemia in rats. J Cereb Blood Flow Metab 2004;24(7):771-779
-
(2004)
J Cereb Blood Flow Metab
, vol.24
, Issue.7
, pp. 771-779
-
-
Yoshida, M.1
Nakakimura, K.2
Cui, Y.J.3
-
39
-
-
0037405193
-
ATP channel opening
-
D'Souza SP, Yellon DM, Martin C, et al. B-type natriuretic peptide limits infarct size in rat isolated hearts via KATP channel opening. Am J Physiol Heart Circ Physiol 2003;284(5):H1592-600 (Pubitemid 36460771)
-
(2003)
American Journal of Physiology - Heart and Circulatory Physiology
, vol.284
, Issue.5
-
-
D'Souza, S.P.1
Yellon, D.M.2
Martin, C.3
Schulz, R.4
Heusch, G.5
Onody, A.6
Ferdinandy, P.7
Baxter, G.F.8
-
40
-
-
0036713816
-
Pharmacological preconditioning ameliorates neurological injury in a model of spinal cord ischemia
-
Caparrekku DJ, Cattaneao SM 2nd, Sethea BT, et al. Pharmacological preconditioning ameliorates neurological injury in a model of spinal cord ischemia. Ann Thorac Surg 2002;74(3):838-844
-
(2002)
Ann Thorac Surg
, vol.74
, Issue.3
, pp. 838-844
-
-
Caparrekku, D.J.1
Cattaneao II, S.M.2
Sethea, B.T.3
-
41
-
-
33751261138
-
Endothelium-dependent regulation of cerebrovascular tone by extracellular and intracellular ATP
-
Janigro D, Ngyyen TS, Meno J, et al. Endothelium-dependent regulation of cerebrovascular tone by extracellular and intracellular ATP. Am J Physiol 1997;273(2 Pt 2):H878-85 (Pubitemid 27392244)
-
(1997)
American Journal of Physiology - Heart and Circulatory Physiology
, vol.273
, Issue.2
-
-
Janigro, D.1
Nguyen, T.-S.2
Meno, J.3
West, G.A.4
Richard Winn, H.5
-
42
-
-
0029948971
-
+ channels may be impaired during acute cerebral ischemia in spontaneously hypertensive rats
-
DOI 10.1016/0165-1838(95)00123-9
-
Nishimura M, Takahashi H, Nanbu A, et al. Cerebral adenosine triphosphate-sensitive K+ channels may be impaired during acute cerebral ischemia in spontaneously hypertensive rats. J Auton Nerv Syst 1996;58(3):139-146 (Pubitemid 26167170)
-
(1996)
Journal of the Autonomic Nervous System
, vol.58
, Issue.3
, pp. 139-146
-
-
Nishimura, M.1
Takahashi, H.2
Nanbu, A.3
Sakamoto, M.4
Nakanishi, T.5
Yoshimura, M.6
-
43
-
-
0029058583
-
Ion channel involvement in anoxic depolarization induced by cardiac arrest in rat brain
-
Xie Y, Zacharias E, Hoff P, Tegtmeier F. Ion channel involvement in anoxic depolarization induced by cardiac arrest in rat brain. J Cereb Blood Flow Metab 1995;15(4):587-594
-
(1995)
J Cereb Blood Flow Metab
, vol.15
, Issue.4
, pp. 587-594
-
-
Xie, Y.1
Zacharias, E.2
Hoff, P.3
Tegtmeier, F.4
-
44
-
-
0029585250
-
+ channels in arterial pressure regulation during acute cerebral ischaemia in SHR and WKY rats
-
Nishimura M, Nanbu A, Sakamoto M, et al. Role of cerebral ATP-sensitive K+ channels in arterial pressure regulation during acute cerebral ischaemia in SHR and WKY rats. Clin Exp Pharmacol Physiol Suppl 1995;22(1):S70-2 (Pubitemid 26062046)
-
(1995)
Clinical and Experimental Pharmacology and Physiology
, vol.22
, Issue.SUPPL. 1
-
-
Nishimura, M.1
Nanbu, A.2
Sakamoto, M.3
Nakanishi, T.4
Takahashi, H.5
Yoshimura, M.6
-
45
-
-
38949128011
-
Role of transporters and ion channels in neuronal injury under hypoxia
-
Xue J, Zhou D, Yao H, et al. Role of transporters and ion channels in neuronal injury under hypoxia. Am J Physiol Regul Integr Comp Physiol 2007;294(2):R451-7
-
(2007)
Am J Physiol Regul Integr Comp Physiol
, vol.294
, Issue.2
-
-
Xue, J.1
Zhou, D.2
Yao, H.3
-
46
-
-
35348881422
-
+ channels and GABA
-
DOI 10.1007/s11373-007-9190-2
-
Thompson JW, Prentice HM, Lutz PL. Regulation of extracellular glutamate levels in the long-term anoxic turtle striatum: coordinated activity of glutamate transporters, adenosine, K+ATP channels and GABA. J Biomed Sci 2007;14(6):809-817 (Pubitemid 47573154)
-
(2007)
Journal of Biomedical Science
, vol.14
, Issue.6
, pp. 809-817
-
-
Thompson, J.W.1
Prentice, H.M.2
Lutz, P.L.3
-
47
-
-
33645988795
-
Activation of ATP-sensitive K channels protects hippocampal CA1 neurons from hypoxia by suppressing p53 expression
-
2206
-
Huang L, Li W, Li B, Zou F. Activation of ATP-sensitive K channels protects hippocampal CA1 neurons from hypoxia by suppressing p53 expression. Neurosci Lett 2206;398(1-2):34-38
-
Neurosci Lett
, vol.398
, Issue.1-2
, pp. 34-38
-
-
Huang, L.1
Li, W.2
Li, B.3
Zou, F.4
-
48
-
-
9644252715
-
ATP channel and protein kinase C-ε in heart-derived H9c2 cells
-
DOI 10.1016/j.ejphar.2004.10.037, PII S0014299904012221
-
Moon CH, Kim MY, Kim MJ, et al. KR-31378, a novel benzopyran analog, attenuates hypoxia-induced cell death via mitochondrial KATP channel and protein kinase C-epsilon in heart-derived H9c2 cells. Eur J Pharmacol 2004;506(1):27-35 (Pubitemid 39575082)
-
(2004)
European Journal of Pharmacology
, vol.506
, Issue.1
, pp. 27-35
-
-
Moon, C.-H.1
Kim, M.-Y.2
Kim, M.J.3
Kim, M.H.4
Lee, S.5
Yi, K.Y.6
Yoo, S.E.7
Lee, D.-H.8
Lim, H.9
Kim, H.S.10
Lee, S.H.11
Baik, E.J.12
Jung, Y.-S.13
-
49
-
-
0037185409
-
+ channels in dorsal vagal neurons of juvenile mice in situ
-
DOI 10.1016/S0306-4522(01)00498-5, PII S0306452201004985
-
Müller M, Brockhaus J, Ballanyi K. ATP-independent anoxic activation of ATP-sensitive K+ channels in dorsal vagal neurons of juvenile mice in situ. Neuroscience 2002;109(2):313-328 (Pubitemid 34098971)
-
(2002)
Neuroscience
, vol.109
, Issue.2
, pp. 313-328
-
-
Muller, M.1
Brockhaus, J.2
Ballanyi, K.3
-
50
-
-
36248955063
-
ATP Channel Subunit, Kir6.2, is associated with decreased expression of neuropeptide Y and agouti-related protein in the hypothalami of zucker diabetic fatty rats
-
DOI 10.1111/j.1365-2826.2007.01607.x
-
Gyte A, Pritchard LE, Jones HB, et al. Reduced expression of the KATP channel subunit, Kir6.2, is associated with decreased expression of neuropeptide Y and agouti-related protein in the hypothalami of Zucker diabetic fatty acids. J Neuroendocrinol 2007;19(12):941-951 (Pubitemid 350131080)
-
(2007)
Journal of Neuroendocrinology
, vol.19
, Issue.12
, pp. 941-951
-
-
Gyte, A.1
Pritchard, L.E.2
Jones, H.B.3
Brennand, J.C.4
White, A.5
-
51
-
-
0035042796
-
+ channels in the hypothalamus are essential for the maintenance of glucose homeostasis
-
Miki T, Liss B, Minami K, et al. ATP-sensitive K+ channels in the hypothalamus are essential for the maintenance of glucose metabolism. Nat Neurosci 2001;4(5):507-512 (Pubitemid 32397188)
-
(2001)
Nature Neuroscience
, vol.4
, Issue.5
, pp. 507-512
-
-
Miki, T.1
Liss, B.2
Minami, K.3
Shiuchi, T.4
Saraya, A.5
Kashima, Y.6
Horiuchi, M.7
Ashcroft, F.8
Minokoshi, Y.9
Roeper, J.10
Seino, S.11
-
52
-
-
0033944152
-
+ channels in hypothalamic neurons of lean, but not obese rats
-
DOI 10.1038/77660
-
Spanswick D, Smith MA, Mirshamsi S, et al. Insulin activates ATP-sensitive K+ channels in hypothalamic neurons of lean, but not obese rats. Nat Neurosci 2000;3(8):757-758 (Pubitemid 30485698)
-
(2000)
Nature Neuroscience
, vol.3
, Issue.8
, pp. 757-758
-
-
Spanswick, D.1
Smith, M.A.2
Mirshamsi, S.3
Routh, V.H.4
Ashford, M.L.J.5
-
53
-
-
0032517821
-
+ channel in rat brain
-
DOI 10.1016/S0006-8993(98)00956-1, PII S0006899398009561
-
Dunn-Meynell AA, Rawson NE, Levin BE. Distribution and phenotype of neurons containing the ATP-sensitive K+ channel in rat brain. Brain Res 1998;814(1-2):41-54 (Pubitemid 29023410)
-
(1998)
Brain Research
, vol.814
, Issue.1-2
, pp. 41-54
-
-
Dunn-Meynell, A.A.1
Rawson, N.E.2
Levin, B.E.3
-
54
-
-
1542343927
-
+ Channels and Their Role in Cardioprotection
-
DOI 10.1161/01.RES.0000117583.66950.43
-
O'Rourke B. Evidence for mitochondrial K+ channels and their role in cardioprotection. Circ Res 2004;94:420-432 (Pubitemid 38326277)
-
(2004)
Circulation Research
, vol.94
, Issue.4
, pp. 420-432
-
-
O'Rourke, B.1
-
55
-
-
20644462354
-
ATP channels and an overview of alternative mechanisms
-
DOI 10.1016/j.yjmcc.2005.04.002, PII S0022282805001264
-
Hanley PJ, Daut J. KATP channels and preconditioning: a re-examination of the role of mitochondrial KATP channels an overview of alternative mechanisms. J Mol Cell Cardiol 2005;39:17-50 (Pubitemid 40836043)
-
(2005)
Journal of Molecular and Cellular Cardiology
, vol.39
, Issue.1
, pp. 17-50
-
-
Hanley, P.J.1
Daut, J.2
-
56
-
-
1242337465
-
ATP Channel Openers: Structure-Activity Relationships and Therapeutic Potential
-
DOI 10.1002/med.10060
-
Mannhold R. KATP channel openers: structure-activity relationships and therapeutic potential. Med Res Rev 2004;24(2):213-266 (Pubitemid 38230680)
-
(2004)
Medicinal Research Reviews
, vol.24
, Issue.2
, pp. 213-266
-
-
Mannhold, R.1
-
57
-
-
0346333100
-
Regulation by Sulfanylurea Receptor Type 1 of a Non-selective Cation Channel Involved in Cytotoxic Edema of Reactive Astrocytes
-
DOI 10.1097/00008506-200401000-00021
-
Simard JM, Chen M. Regulation by sulfanylurea receptor type 1 of a non-selective cation channel involved in cytotoxic edema of reactive astrocytes. J Neurosurg Anesthesiol 2004;16(1):98-99 (Pubitemid 38057409)
-
(2004)
Journal of Neurosurgical Anesthesiology
, vol.16
, Issue.1
, pp. 98-99
-
-
Simard, J.M.1
Chen, M.2
-
58
-
-
38649104857
-
Drugs acting on SUR1 to treat CNS ischemia and trauma
-
DOI 10.1016/j.coph.2007.10.004, PII S1471489207001750
-
Simard JM, Woo SK, Bhatta S, Gerzanich V. Drugs acting on SUR1 to treat CNS ischemia and trauma. Curr Opin Pharmacol 2008;8(1):42-49 (Pubitemid 351168694)
-
(2008)
Current Opinion in Pharmacology
, vol.8
, Issue.1
, pp. 42-49
-
-
Simard, J.M.1
Woo, S.K.2
Bhatta, S.3
Gerzanich, V.4
-
59
-
-
38149069674
-
ATP-sensitive potassium channels: Novel potential roles in Parkinson's disease
-
Zeng J, Wang G, Chen SD. ATP-sensitive potassium channels: novel potential roles in Parkinson's disease. Neurosci Bull 2007;23(6):106-121
-
(2007)
Neurosci Bull
, vol.23
, Issue.6
, pp. 106-121
-
-
Zeng, J.1
Wang, G.2
Chen, S.D.3
-
60
-
-
38649087364
-
Inhalational anesthetics as preconditioning agents in ischemic brain
-
DOI 10.1016/j.coph.2007.09.005, PII S1471489207001610
-
Wang L, Traystman RJ, Murphy SJ. Inhalation anesthetics as preconditioning agents in ischemic brain. Curr Opin Pharmacol 2008;8(1):104-110 (Pubitemid 351168690)
-
(2008)
Current Opinion in Pharmacology
, vol.8
, Issue.1
, pp. 104-110
-
-
Wang, L.1
Traystman, R.J.2
Murphy, S.J.3
-
61
-
-
33847268582
-
Anesthetic-mediated protection/preconditioning during cerebral ischemia
-
DOI 10.1016/j.lfs.2006.12.022, PII S0024320507000240
-
Clarkson AN. Anesthetic-mediated protection/preconditioning during cerebral ischemia. Life Sci 2007;80:1157-1175 (Pubitemid 46329012)
-
(2007)
Life Sciences
, vol.80
, Issue.13
, pp. 1157-1175
-
-
Clarkson, A.N.1
-
62
-
-
19444368582
-
Neuroprotection by KATP channels
-
Yamada K, Inagaki N. Neuroprotection by KATP channels. J Mol Cell Cardiol 2005;38(6):945-949
-
(2005)
J Mol Cell Cardiol
, vol.38
, Issue.6
, pp. 945-949
-
-
Yamada, K.1
Inagaki, N.2
-
63
-
-
20344374724
-
ATP channels
-
DOI 10.1615/CritRevNeurobiol.v16.i4.20
-
Phillis JW. Adenosine and adenine nucleotides as regulators of cerebral blood flow: roles of acidosis, cell swelling, and KATP channels. Crit Rev Neurobiol 2004;16(4):237-270 (Pubitemid 40781082)
-
(2004)
Critical Reviews in Neurobiology
, vol.16
, Issue.4
, pp. 237-270
-
-
Phillis, J.W.1
-
65
-
-
19444377293
-
ATP channels as metabolic sensors in acute metabolic changes
-
DOI 10.1016/j.yjmcc.2004.11.019, PII S0022282804003591
-
Miki T, Seino S. Roles of KATP channels as metabolic sensors in acute metabolic changes. J Mol Cell Cardiol 2005;38(6):917-925 (Pubitemid 40725939)
-
(2005)
Journal of Molecular and Cellular Cardiology
, vol.38
, Issue.6
, pp. 917-925
-
-
Miki, T.1
Seino, S.2
-
66
-
-
9444223977
-
+ channels as metabolic sensors: Studies of Kir6.x null mice
-
DOI 10.2337/diabetes.53.suppl-3.S176
-
Minami K, Miki T, Kadowaki T, Seino S. Roles of ATP-sensitive K+ channels as metabolic sensors: studies of Kir6.x null mice. Diabetes 2004;53(Suppl 3):S176-80 (Pubitemid 39564541)
-
(2004)
Diabetes
, vol.53
, Issue.SUPPL. 3
-
-
Minami, K.1
Miki, T.2
Kadowaki, T.3
Seino, S.4
-
67
-
-
33846262003
-
2 signaling in the nigrostriatal dopamine pathway via ATP-sensitive potassium channels: Issues and answers
-
DOI 10.1089/ars.2007.9.219
-
Avshalumov MV, Bao L, Patel JC, Rice ME. H2O2 signaling in the nigrostriatal dopamine pathway via ATP-sensitive potassium channels: issues and answers. Antioxid Redox Signal 2007;9(2):219-231 (Pubitemid 46105421)
-
(2007)
Antioxidants and Redox Signaling
, vol.9
, Issue.2
, pp. 219-231
-
-
Avshalumov, M.V.1
Bao, L.2
Patel, J.C.3
Rice, M.E.4
-
68
-
-
38349093358
-
KATP channel pharmacogenomics: From bench to bedside
-
Sattiraju S, Reyes S, Kane GC, Terzic A. KATP channel pharmacogenomics: from bench to bedside. Clin Pharmacol Ther 2008;83(2):354-357
-
(2008)
Clin Pharmacol Ther
, vol.83
, Issue.2
, pp. 354-357
-
-
Sattiraju, S.1
Reyes, S.2
Kane, G.C.3
Terzic, A.4
-
69
-
-
33645322386
-
KATP channels as molecular sensors of cellular metabolism
-
Nichols CG. KATP channels as molecular sensors of cellular metabolism. Nature 2006;440(7083):470-476
-
(2006)
Nature
, vol.440
, Issue.7083
, pp. 470-476
-
-
Nichols, C.G.1
-
71
-
-
4644362977
-
ATP channels in brain hypoxia
-
DOI 10.1242/jeb.01106
-
Ballanyi K. Protective role of neuronal KATP channels in brain hypoxia. J Exp Biol 2004;207(Pt 18):3201-3212 (Pubitemid 39275294)
-
(2004)
Journal of Experimental Biology
, vol.207
, Issue.18
, pp. 3201-3212
-
-
Ballanyi, K.1
-
73
-
-
34548676568
-
Role of adenosine triphosphate-sensitive potassium channel inhibition in shock states: Physiology and clinical implications
-
DOI 10.1097/shk.0b013e318050c836, PII 0002438220071000000004
-
Lange M, Morelli A, Ertmer C, et al. Role of adenosine triphosphate-sensitive potassium channel inhibition in shock states: physiology and clinical implications. Shock 2007;28(4):394-400 (Pubitemid 47415248)
-
(2007)
Shock
, vol.28
, Issue.4
, pp. 394-400
-
-
Lange, M.1
Morelli, A.2
Ertmer, C.3
Broking, K.4
Rehberg, S.5
Aken, H.V.6
Traber, D.L.7
Westphal, M.8
-
74
-
-
33748439683
-
Human ether-a-go-go-related (HERG) gene and ATP-sensitive potassium channels as targets for adverse drug effects
-
DOI 10.1016/j.pharmthera.2006.03.002, PII S0163725806000313
-
Zünkler BJ. Human ether-a-go-go-related (HERG) gene and ATP-sensitive potassium channels as targets for adverse drug effects. Pharmacol Ther 2006;112(1):12-37 (Pubitemid 44339547)
-
(2006)
Pharmacology and Therapeutics
, vol.112
, Issue.1
, pp. 12-37
-
-
Zunkler, B.J.1
-
75
-
-
0037306308
-
+ channels
-
DOI 10.1016/S0079-6107(02)00053-6, PII S0079610702000536
-
Seino S, Miki T. Physiological and pathophysiological roles of ATP-sensitive K+ channels. Prog Biophys Mol Biol 2003;81:133-176 (Pubitemid 36141258)
-
(2003)
Progress in Biophysics and Molecular Biology
, vol.81
, Issue.2
, pp. 133-176
-
-
Seino, S.1
Miki, T.2
-
76
-
-
0030772859
-
ATP-sensitive and inwardly rectifying potassium channels in smooth muscle
-
Quayle JM, Nelson MT, Standen NB. ATP-sensitive and inwardly rectifying potassium channels in smooth muscle. Physiol Rev 1997;77(4):1165-1232 (Pubitemid 27459582)
-
(1997)
Physiological Reviews
, vol.77
, Issue.4
, pp. 1165-1232
-
-
Quayle, J.M.1
Nelson, M.T.2
Standen, N.B.3
-
77
-
-
0029871919
-
+ channel with a novel structure
-
Lesage F, Guillemare E, Fink M, et al. TWIK-1, ubiquitous human weakly inward rectifying K+ channel with a novel structure. EMBO J 1996;15(5):1004-1011 (Pubitemid 26077828)
-
(1996)
EMBO Journal
, vol.15
, Issue.5
, pp. 1004-1011
-
-
Lesage, F.1
Guillemare, E.2
Fink, M.3
Duprat, F.4
Lazdunski, M.5
Romey, G.6
Barhanin, J.7
-
78
-
-
0029831704
-
+ channel subunits via a disulfide bridge
-
Lesage F, Reyes R, Fink M, et al. Dimerization of TWIK-1 K+ channel subunits via a disulfide bridge. EMBO J 1996;15(23):6400-6407 (Pubitemid 26413773)
-
(1996)
EMBO Journal
, vol.15
, Issue.23
, pp. 6400-6407
-
-
Lesage, F.1
Reyes, R.2
Fink, M.3
Duprat, F.4
Guillemare, E.5
Lazdunski, M.6
-
79
-
-
0030451916
-
+ channel
-
Fink M, Duprat F, Lesage F, et al. Cloning, functional expression and brain localization of a novel unconventional outward rectifier K+ channel. EMBO J 1996;15(24):6854-6862 (Pubitemid 27023256)
-
(1996)
EMBO Journal
, vol.15
, Issue.24
, pp. 6854-6862
-
-
Fink, M.1
Duprat, F.2
Lesage, F.3
Reyes, R.4
Romey, G.5
Heurteaux, C.6
Lazdunski, M.7
-
80
-
-
0030821520
-
+ channel to sense external pH variations near physiological pH
-
DOI 10.1093/emboj/16.17.5464
-
Duprat F, Lesage F, Fink M, et al. TASK, a human background K+ channel to sense external pH variations near physiological pH. EMBO J 1997;16(17):5464- 5471 (Pubitemid 27380153)
-
(1997)
EMBO Journal
, vol.16
, Issue.17
, pp. 5464-5471
-
-
Duprat, F.1
Lesage, F.2
Fink, M.3
Reyes, R.4
Heurteaux, C.5
Lazdunski, M.6
-
81
-
-
0029099458
-
A new family of outwardly rectifying potassium channel proteins with two pore domains in tandem
-
Ketchum KA, Joiner WJ, Sellers AJ, et al. A new family of outwardly rectifying potassium channel proteins with two pore domains in tandem. Nature 1995;376:690-695
-
(1995)
Nature
, vol.376
, pp. 690-695
-
-
Ketchum, K.A.1
Joiner, W.J.2
Sellers, A.J.3
-
82
-
-
0029150459
-
YKC1 encodes the depolarization-activated K+ channel in the plasma membrane of yeast
-
Zhou XL, Vaillant B, Loukin SH, et al. YKC1 encodes the depolarization-activated K+ channel in the plasma membrane of yeast. FEBS Lett 1995;373:170-176
-
(1995)
FEBS Lett
, vol.373
, pp. 170-176
-
-
Zhou, X.L.1
Vaillant, B.2
Loukin, S.H.3
-
83
-
-
0030064010
-
+ channel with two pore domains and novel gating properties
-
DOI 10.1074/jbc.271.8.4183
-
Lesage F, Guillemare E, Fink M, et al. A pH-sensitive yeast outward rectifier K+ channels with two pore domains and novel gating properties. J Biol Chem 1996;271(8):4183-4187 (Pubitemid 26070519)
-
(1996)
Journal of Biological Chemistry
, vol.271
, Issue.8
, pp. 4183-4187
-
-
Lesage, F.1
Guillemare, E.2
Fink, M.3
Duprat, F.4
Lazdunski, M.5
Romey, G.6
Barhanin, J.7
-
84
-
-
0032526428
-
+ channel stimulated by arachidonic acid and polyunsaturated fatty acids
-
DOI 10.1093/emboj/17.12.3297
-
Fink M, Lesage F, Duprat F, et al. A neuronal two P domain K+ channel stimulated by arachidonic acid and polyunsaturated fatty acids. EMBO J 1998;17(12):3297-3308 (Pubitemid 28279504)
-
(1998)
EMBO Journal
, vol.17
, Issue.12
, pp. 3297-3308
-
-
Fink, M.1
Lesage, F.2
Duprat, F.3
Heurteaux, C.4
Reyes, R.5
Fosset, M.6
Lazdunski, M.7
-
85
-
-
0031036705
-
The structure and distribution of the mouse TWIK-1 K+ channel
-
Lesage F, Lauritzen I, Duprat F, et al. The structure and distribution of the mouse TWIK-1 K+ channel. FEBS Lett 1997;402(1):28-32
-
(1997)
FEBS Lett
, vol.402
, Issue.1
, pp. 28-32
-
-
Lesage, F.1
Lauritzen, I.2
Duprat, F.3
-
86
-
-
39149099949
-
Changes in expression of some two-pore domain potassium channel genes (KNCK) in selected brain regions of developing mice
-
Aller MI, Wisden W. Changes in expression of some two-pore domain potassium channel genes (KNCK) in selected brain regions of developing mice. Neurosci 2008;151:1154-1172
-
(2008)
Neurosci
, vol.151
, pp. 1154-1172
-
-
Aller, M.I.1
Wisden, W.2
-
87
-
-
0024384172
-
Potassium channels in cardiac cells activated by arachidonic acid and phospholipids
-
Kim D, Clapham DE. Potassium channels in cardiac cells activated by arachidonic acid and phospholipids. Science 1989;244:1174-1179
-
(1989)
Science
, vol.244
, pp. 1174-1179
-
-
Kim, D.1
Clapham, D.E.2
-
88
-
-
0037438060
-
Traumatic brain injury-induced acute gene expression changes in rat cerebral cortex identified by GeneChip analysis
-
DOI 10.1002/jnr.10486
-
Rao VLR, Dhodda VK, Song G, et al. Traumatic brain injury-induced acute gene expression changes in rat cerebral cortex identified by GeneChip analysis. J Neurosci Res 2003;71(2):208-219 (Pubitemid 36055465)
-
(2003)
Journal of Neuroscience Research
, vol.71
, Issue.2
, pp. 208-219
-
-
Rao, V.L.R.1
Dhodda, V.K.2
Song, G.3
Bowen, K.K.4
Dempsey, R.J.5
-
89
-
-
53849147848
-
Altered neuronal expression if TASK1 and TASK3 potassium channels in rodent and human autoimmune CNS inflammation
-
Meuth SG, Kanyshkova T, Melzer N, et al. Altered neuronal expression if TASK1 and TASK3 potassium channels in rodent and human autoimmune CNS inflammation. Neurosci Lett 2008;446:133-138
-
(2008)
Neurosci Lett
, vol.446
, pp. 133-138
-
-
Meuth, S.G.1
Kanyshkova, T.2
Melzer, N.3
-
90
-
-
0029032812
-
Arachidonic acid activation of a new family of K+ channels in cultured rat neuronal cells
-
Lond
-
Kim D, Sladek CD, Aguando-Velasco C, et al. Arachidonic acid activation of a new family of K+ channels in cultured rat neuronal cells. J Physiol (Lond) 1995;484:643-660
-
(1995)
J Physiol
, vol.484
, pp. 643-660
-
-
Kim, D.1
Sladek, C.D.2
Aguando-Velasco, C.3
-
91
-
-
0034678889
-
Polyunsaturated fatty acids are potent neuroprotectors
-
Lauritzen I, Blondeau N, Heurteaux C, et al. Polyunsaturated fatty acids are potent neuroprotectors. EMBO J 2000;19(8):1784-1793 (Pubitemid 30204390)
-
(2000)
EMBO Journal
, vol.19
, Issue.8
, pp. 1784-1793
-
-
Lauritzen, I.1
Blondeau, N.2
Heurteaux, C.3
Widmann, C.4
Romey, G.5
Lazdunski, M.6
-
92
-
-
0036713459
-
Hypoxic depolarization of cerebellar granule neurons by specific inhibition of TASK-1
-
DOI 10.1161/01.STR.0000027440.68031.B0
-
Plant LD, Kemp PJ, Peers C, et al. Hypoxia depolarization of cerebellar granule neurons by specific inhibition of TASK-1. Stroke 2002;33:2324-2328 (Pubitemid 35014650)
-
(2002)
Stroke
, vol.33
, Issue.9
, pp. 2324-2328
-
-
Plant, L.D.1
Kemp, P.J.2
Peers, C.3
Henderson, Z.4
Pearson, H.A.5
-
93
-
-
0037384960
-
+ channels in central neuroprotection
-
DOI 10.1113/jphysiol.2003.040048
-
Miller P, Kemp PJ, Lewis A, et al. Acute hypoxia occludes hTREK-1 modulation: re-evaluation of the potential role of tandem P domain K+ channels in central neuroprotection. J Physiol (Lond) 2003;548(1):31-37 (Pubitemid 36410795)
-
(2003)
Journal of Physiology
, vol.548
, Issue.1
, pp. 31-37
-
-
Miller, P.1
Kemp, P.J.2
Lewis, A.3
Chapman, C.G.4
Meadows, H.J.5
Peers, C.6
-
94
-
-
0742270740
-
Polymodal regulation of hTREK1 by pH, arachidonic acid, and hypoxia: Physiological impact in acidosis and alkalosis
-
Miller P, Peers C, Kemp PJ. Polymodal regulation of hTREK1 by pH, arachidonic acid, and hypoxia: physiological impact in acidosis and alkalosis. Am J Physiol Cell Physiol 2004;286:C272-82 (Pubitemid 38146351)
-
(2004)
American Journal of Physiology - Cell Physiology
, vol.286
, Issue.2
-
-
Miller, P.1
Peers, C.2
Kemp, P.J.3
-
95
-
-
1642450667
-
Alterations in the expression of lipid and mechano-gated two-pore domain potassium channel genes in rat brain following chronic cerebral ischemia
-
DOI 10.1016/j.molbrainres.2003.09.020
-
Xu X, Pan Y, Wang X. Alterations in the expression of lipid and mechano-gated two-pore domain potassium channel genes in rat brain following chronic cerebral ischemia. Brain Res Mol Brain Res 2004;120(2):205-209 (Pubitemid 38115820)
-
(2004)
Molecular Brain Research
, vol.120
, Issue.2
, pp. 205-209
-
-
Xu, X.1
Pan, Y.2
Wang, X.3
-
96
-
-
12344268858
-
Enhanced expressions of arachidonic acid-sensitive tandem-pore domain potassium channels in rat experimental acute cerebral ischemia
-
DOI 10.1016/j.bbrc.2004.12.124, PII S0006291X04028815
-
Li ZB, Zhang HX, Li LL, Wang XL. Enhanced expressions of arachidonic acid-sensitive tandem-pore domain potassium channels in rat experimental acute cerebral ischemia. Biochem Biophys Res Commun 2005;327(4):1163-1169 (Pubitemid 40137988)
-
(2005)
Biochemical and Biophysical Research Communications
, vol.327
, Issue.4
, pp. 1163-1169
-
-
Li, Z.-B.1
Zhang, H.-X.2
Li, L.-L.3
Wang, X.-L.4
-
97
-
-
13444301518
-
The effects of hypoxia on the modulation of human TREK-1 potassium channels
-
DOI 10.1113/jphysiol.2004.076240
-
Caley AJ, Gruss M, Franks NP. The effects of hypoxia on the modulation of human TREK-1 potassium channels. J Physiol (Lond) 2005;562(1):205-212 (Pubitemid 40207797)
-
(2005)
Journal of Physiology
, vol.562
, Issue.1
, pp. 205-212
-
-
Caley, A.J.1
Gruss, M.2
Franks, N.P.3
-
98
-
-
13444274758
-
+ channel TREK-1 is resistant to hypoxia: Implication for ischaemic neuroprotection
-
DOI 10.1113/jphysiol.2004.077503
-
Buckler KJ, Honoré E. The lipid-activated two-pore domain K+ channel TREK-1 is resistant to hypoxia: implication for ischaemic neuroprotection. J Physiol (Lond) 2005;562(1):213-222 (Pubitemid 40207798)
-
(2005)
Journal of Physiology
, vol.562
, Issue.1
, pp. 213-222
-
-
Buckler, K.J.1
Honore, E.2
-
99
-
-
29744459904
-
Alpha-linolenic acid and riluzole treatment confer cerebral protection and improve survival after focal brain ischemia
-
DOI 10.1016/j.neuroscience.2005.08.083, PII S0306452205010262
-
Heurteaux C, Laigle C, Blondeau N, et al. Alpha-linolenic acid and riluzole treatment confer cerebral protection and improve survival after focal brain ischemia. Neuroscience 2006;137(1):241-251 (Pubitemid 43031491)
-
(2006)
Neuroscience
, vol.137
, Issue.1
, pp. 241-251
-
-
Heurteaux, C.1
Laigle, C.2
Blondeau, N.3
Jarretou, G.4
Lazdunski, M.5
-
100
-
-
34547561344
-
Polyunsaturated fatty acids are cerebral vasodilators via the TREK-1 potassium channel
-
DOI 10.1161/CIRCRESAHA.107.154443, PII 0000301220070720000011
-
Blondeau N, Pétrault O, Manta S, et al. Polyunsaturated fatty acids are cerebral vasodilators via the TREK-1 potassium channel. Circ Res 2007;101:176-184 (Pubitemid 47196585)
-
(2007)
Circulation Research
, vol.101
, Issue.2
, pp. 176-184
-
-
Blondeau, N.1
Petrault, O.2
Manta, S.3
Giordanengo, V.4
Gounon, P.5
Bordet, R.6
Lazdunski, M.7
Heurteaux, C.8
-
101
-
-
0035854748
-
+ Channel
-
DOI 10.1074/jbc.M010357200
-
Hartness ME, Lewis A, Searle GJ, et al. Combined antisense and pharmacological approaches implicate hTASK as an airway O2 sensing K+ channels. J Biochem Chem 2001;276(28):26499-26508 (Pubitemid 37412871)
-
(2001)
Journal of Biological Chemistry
, vol.276
, Issue.28
, pp. 26499-26508
-
-
Hartness, M.E.1
Lewis, A.2
Searle, G.J.3
O'Kelly, I.4
Peers, C.5
Kemp, P.J.6
-
103
-
-
26244462635
-
+ channels heterologously expressed in human embryonic kidney cells
-
DOI 10.1016/j.neuroscience.2005.07.009, PII S0306452205007530
-
Campanucci VA, Brown ST, Judasek K, O'Kelly IM. O2 sensing by recombinant TWIK-related halothane-inhabitable K+ channel-1 background K+ channels heterologously expressed in human embryonic kidney cells. Neuroscience 2005;135(4):1087-1094 (Pubitemid 41416672)
-
(2005)
Neuroscience
, vol.135
, Issue.4
, pp. 1087-1094
-
-
Campanucci, V.A.1
Brown, S.T.2
Hudasek, K.3
O'Kelly, I.M.4
Nurse, C.A.5
Fearon, I.M.6
-
104
-
-
18844374152
-
2 sensing by the human tandem-P domain channel, hTREK1
-
DOI 10.1016/j.bbrc.2005.04.042, PII S0006291X05008260
-
Miller P, Kemp PJ, Peers C. Structural requirements for O2 sensing by the human tandem-P domain, hTREK1. Biochem Biophys Res Commun 2005;331:1253-1256 (Pubitemid 40692491)
-
(2005)
Biochemical and Biophysical Research Communications
, vol.331
, Issue.4
, pp. 1253-1256
-
-
Miller, P.1
Kemp, P.J.2
Peers, C.3
-
105
-
-
34249802903
-
Hydrogen peroxide selectively increases TREK-2 currents via myosin light chain kinases
-
DOI 10.2741/2176
-
Kim Y, Lee SH, Ho WK. Hydrogen peroxide selectively increases TREK-2 currents via myosin light chain kinases. Front Biosci 2007;12:1642-1650 (Pubitemid 46846796)
-
(2007)
Frontiers in Bioscience
, vol.12
, Issue.5
, pp. 1642-1650
-
-
Kim, Y.1
Lee, S.-H.2
Ho, W.-K.3
-
106
-
-
3342981356
-
+ channel involved in neuroprotection and general anesthesia
-
DOI 10.1038/sj.emboj.7600234
-
Heurteaux C, Guy N, Laigle C, et al. TREK-1, a K+ channel involved in neuroprotection and general anesthesia. EMBO J 2004;23:2684-2695 (Pubitemid 38988239)
-
(2004)
EMBO Journal
, vol.23
, Issue.13
, pp. 2684-2695
-
-
Heurteaux, C.1
Guy, N.2
Laigle, C.3
Blondeau, N.4
Duprat, F.5
Mazzuca, M.6
Lang-Lazdunski, L.7
Widmann, C.8
Zanzouri, M.9
Romey, G.10
Lazdunski, M.11
-
107
-
-
25644437040
-
2P channel TRESK
-
DOI 10.1213/01.ane.0000168447.87557.5a
-
Keshavaprasad B, Liu C, Au JD, et al. Species-specific differences in response to anesthetics and other modulators by the K2P channel TRESK. Anesth Analg 2005;101:1042-1049 (Pubitemid 41383070)
-
(2005)
Anesthesia and Analgesia
, vol.101
, Issue.4
, pp. 1042-1049
-
-
Keshavaprasad, B.1
Liu, C.2
Au, J.D.3
Kindler, C.H.4
Cotten, J.F.5
Yost, C.S.6
-
108
-
-
33645877403
-
The in vivo contributions of TASK-1-containing channels to the actions of inhalation anesthetics, the α2 adrenergic sedative dexmedetomidine, and cannabinoid agonists
-
Linden AM, Aller MI, Leppä E, et al. The in vivo contributions of TASK-1-containing channels to the actions of inhalation anesthetics, the α2 adrenergic sedative dexmedetomidine, and cannabinoid agonists. J Pharmcol Exp Ther 2006;317(2):615-626
-
(2006)
J Pharmcol Exp Ther
, vol.317
, Issue.2
, pp. 615-626
-
-
Linden, A.M.1
Aller, M.I.2
Leppä, E.3
-
109
-
-
17444411944
-
+ channels TREK-2 and TRAAK
-
DOI 10.1113/jphysiol.2004.081059
-
Kang D, Choe C, Kim D. Thermosensitivity of the two-pore domain K+ channels TREK-2 and TRAAK. J Physiol (Lond) 2005;564(1):103-116 (Pubitemid 40542191)
-
(2005)
Journal of Physiology
, vol.564
, Issue.1
, pp. 103-116
-
-
Kang, D.1
Choe, C.2
Kim, D.3
-
110
-
-
0033578649
-
Mechano- Or acid stimulation, two interactive modes of activation of the TREK-1 potassium channel
-
Maingret F, Patel AJ, Lesage F, et al. Mechano- or acid stimulation, two interactive modes of activation of the TREK-1 potassium channel. J Biochem Chem 1999;274(38):26691-26696 (Pubitemid 129520183)
-
(1999)
Journal of Biological Chemistry
, vol.274
, Issue.38
, pp. 26691-26696
-
-
Maingret, F.1
Patel, A.J.2
Lesage, F.3
Lazdunski, M.4
Honore, E.5
-
111
-
-
33646469698
-
Desensitization of mechano-gated K2P channels
-
Honoré E, Patel AJ, Chemin J, et al. Desensitization of mechano-gated K2P channels. Proc Natl Acad Sci 2006;103(18):6859-6864
-
(2006)
Proc Natl Acad Sci
, vol.103
, Issue.18
, pp. 6859-6864
-
-
Honoré, E.1
Patel, A.J.2
Chemin, J.3
-
112
-
-
35649001473
-
Identification of a region in the TASK3 two pore domain potassium channel that is critical for its blockade by methanandamide
-
DOI 10.1038/sj.bjp.0707436, PII 0707436
-
Veale EL, Buswell R, Clarke CE, Mathie A. Identification of a region in the TASK3 two pore domain potassium channel that is critical for its blockade by methanandamide. Br J Pharmacol 2007;152:778-786 (Pubitemid 350034980)
-
(2007)
British Journal of Pharmacology
, vol.152
, Issue.5
, pp. 778-786
-
-
Veale, E.L.1
Buswell, R.2
Clarke, C.E.3
Mathie, A.4
-
113
-
-
34347360846
-
q-mediated regulation of TASK3 two-pore domain potassium channels: The role of protein kinase C
-
DOI 10.1124/mol.106.033241
-
Veale EL, Kennard LE, Sutton GL, et al. Gαq-mediated regulation of TASK3 two-pore domain potassium channels: the role of protein kinase C. Mol Pharmacol 2007;71:1666-1675 (Pubitemid 47010919)
-
(2007)
Molecular Pharmacology
, vol.71
, Issue.6
, pp. 1666-1675
-
-
Veale, E.L.1
Kennard, L.E.2
Sutton, G.L.3
MacKenzie, G.4
Sandu, C.5
Mathie, A.6
-
114
-
-
49449100453
-
Regulation of two-pore-domain (K2P) potassium leak channels by the tyrosine kinase inhibitor genistein
-
Gierten J, Fickere E, Bloehs R, et al. Regulation of two-pore-domain (K2P) potassium leak channels by the tyrosine kinase inhibitor genistein. Br J Pharmacol 2008;154:1680-1690
-
(2008)
Br J Pharmacol
, vol.154
, pp. 1680-1690
-
-
Gierten, J.1
Fickere, E.2
Bloehs, R.3
-
115
-
-
47749084647
-
The M1P1 loop of TASK3 K2P channels apposes the selectivity filter and influences channel function
-
Clarke CE, Veale EL, Wyse K, et al. The M1P1 loop of TASK3 K2P channels apposes the selectivity filter and influences channel function. J Biol Chem 2008;283(25):16985-16992
-
(2008)
J Biol Chem
, vol.283
, Issue.25
, pp. 16985-16992
-
-
Clarke, C.E.1
Veale, E.L.2
Wyse, K.3
-
116
-
-
33746530041
-
Control of cardiac rhythm by ORK1, a Drosophila two-pore domain potassium channel
-
Lalevée N, Monier B, Sénatore S, et al. Control of cardiac rhythm by ORK1, a Drosophila two-pore domain potassium channel. Cur Biol 2007;16:1502-1508
-
(2007)
Cur Biol
, vol.16
, pp. 1502-1508
-
-
Lalevée, N.1
Monier, B.2
Sénatore, S.3
-
117
-
-
38749152822
-
Relationship between TWIK-related acid-sensitive K+ channel-1 and TWIK-related acid-sensitive K+ channel-3 expression and the occurrence of central sleep apnea: Experiment with rats
-
in Chinese
-
Zhang C, Wang J, Wang GF, Su L. Relationship between TWIK-related acid-sensitive K+ channel-1 and TWIK-related acid-sensitive K+ channel-3 expression and the occurrence of central sleep apnea: experiment with rats. Zhonghua Yi Xue Za Zhi 2007;87(41):2929-2931 (in Chinese)
-
(2007)
Zhonghua Yi Xue Za Zhi
, vol.87
, Issue.41
, pp. 2929-2931
-
-
Zhang, C.1
Wang, J.2
Wang, G.F.3
Su, L.4
-
118
-
-
34447554374
-
A Ba2+-resistant, acid-sensitive K+ conductance in Na+-absorbing H441 human airway epithelial cells
-
Inglis SK, Brown SG, Constable MJ, et al. A Ba2+-resistant, acid-sensitive K+ conductance in Na+-absorbing H441 human airway epithelial cells. Am J Physiol Lung Cell Mol Physiol 2007;292:L1304-12
-
(2007)
Am J Physiol Lung Cell Mol Physiol
, vol.292
-
-
Inglis, S.K.1
Brown, S.G.2
Constable, M.J.3
-
119
-
-
34548363326
-
Biophysical, pharmacological, and functional characteristics of cloned and native mammalian two-pore domain K+ channels
-
DOI 10.1007/s12013-007-0007-8
-
Lotshaw DP. Biophysical, pharmacological, and functional characteristics of cloned and native mammalian two-pore domain K+ channels. Cell Biochem Biophys 2007;47(2):209-256 (Pubitemid 47338363)
-
(2007)
Cell Biochemistry and Biophysics
, vol.47
, Issue.2
, pp. 209-256
-
-
Lotshaw, D.P.1
-
120
-
-
22944473967
-
Physiology and pharmacology of two-pore domain potassium channels
-
DOI 10.2174/1381612054546824
-
Kim D. Physiology and pharmacology of two-pore domain potassium channels. Curr Pharm Des 2005;11(21):2717-2736 (Pubitemid 41051880)
-
(2005)
Current Pharmaceutical Design
, vol.11
, Issue.21
, pp. 2717-2736
-
-
Kim, D.1
-
122
-
-
33947360830
-
2P channels: Focus on TREK1
-
DOI 10.1038/nrn2117, PII NRN2117
-
Honoré E. The neuronal background K2P channels: focus on TREK1. Nat Rev Neurosci 2007;8(4):251-261 (Pubitemid 46452327)
-
(2007)
Nature Reviews Neuroscience
, vol.8
, Issue.4
, pp. 251-261
-
-
Honore, E.1
-
123
-
-
33846198311
-
Neuronal two-pore-domain potassium channels and their regulation by G protein-coupled receptors
-
DOI 10.1113/jphysiol.2006.121582
-
Mathie A. Neuronal tow-pore-domain potassium channels and their regulation by G protein-coupled receptors. J Physiol (Lond) 2007;578(Pt 2):377-385 (Pubitemid 46092203)
-
(2007)
Journal of Physiology
, vol.578
, Issue.2
, pp. 377-385
-
-
Mathie, A.1
-
124
-
-
20444381721
-
K2P channels and their protein partners
-
DOI 10.1016/j.conb.2005.05.008, PII S0959438805000735
-
Plant LD, Rajan S, Goldstein SA. K2P channels and their protein partners. Curr Opin Neurobiol 2005;15(3):326-333 (Pubitemid 40806445)
-
(2005)
Current Opinion in Neurobiology
, vol.15
, Issue.3 SPEC. ISS
, pp. 326-333
-
-
Plant, L.D.1
Rajan, S.2
Goldstein, S.A.N.3
-
125
-
-
0035371189
-
Properties and modulation of mammalian 2P domain K+ channels
-
Patel AJ, Honoré E. Properties and modulation of mammalian 2P domain K+ channels. Trends Neurosci 2001;24(6):339-346
-
(2001)
Trends Neurosci
, vol.24
, Issue.6
, pp. 339-346
-
-
Patel, A.J.1
Honoré, E.2
-
126
-
-
38749089813
-
Recent advance and possible future in TREK-2: A two-pore potassium channel may involved in the process of NPP, brain ischemia and memory impairment
-
DOI 10.1016/j.mehy.2007.06.016, PII S0306987707004148
-
Huang D, Yu B. Recent advance and possible future in TREK-2: a two-pore potassium channel may involved in the process of NPP, brain ischemia and memory impairment. Med Hypotheses 2008;70(3):618-624 (Pubitemid 351179897)
-
(2008)
Medical Hypotheses
, vol.70
, Issue.3
, pp. 618-624
-
-
Huang, D.1
Yu, B.2
-
127
-
-
35748957186
-
2P channels: Chemo- And nutrient sensors
-
DOI 10.1016/j.tins.2007.08.003, PII S0166223607002445
-
Duprat F, Lauritzen I, Patel A, Honoré E. The TASK background K2P channels: chemo- and nutrient sensors. Trends Neurosci 2007;30(11):573-580 (Pubitemid 350051422)
-
(2007)
Trends in Neurosciences
, vol.30
, Issue.11
, pp. 573-580
-
-
Duprat, F.1
Lauritzen, I.2
Patel, A.3
Honore, E.4
-
128
-
-
33947378367
-
Molecular mechanism of ischemic brain injuries and perspectives of drug therapies for neuroprotection
-
in Japanese
-
Uchino H, Morota S, Hirabayashi G, et al. Molecular mechanism of ischemic brain injuries and perspectives of drug therapies for neuroprotection. Masui 2007;56(3):248-270 (in Japanese)
-
(2007)
Masui
, vol.56
, Issue.3
, pp. 248-270
-
-
Uchino, H.1
Morota, S.2
Hirabayashi, G.3
-
129
-
-
11844297824
-
Protective effects of TASK-3 (KCNK9) and related 2P K channels during cellular stress
-
DOI 10.1016/j.brainres.2004.10.029, PII S0006899304017548
-
Liu C, Cotton JF, Schuyler JA, et al. Protective effects of TASK-3 (KCNK9) and related 2P K channels during cellular stress. Brain Res 2005;1031(2):164-173 (Pubitemid 40093069)
-
(2005)
Brain Research
, vol.1031
, Issue.2
, pp. 164-173
-
-
Liu, C.1
Cotton, J.F.2
Schuyler, J.A.3
Fahlman, C.S.4
Au, J.D.5
Bickler, P.E.6
Yost, C.S.7
-
130
-
-
19344378593
-
Two-pore domain potassium channels: New sites of local anesthetic action and toxicity
-
DOI 10.1016/j.rapm.2004.12.001, PII S109873390400611X
-
Kindler CH, Yost CS. Two-pore domain potassium channels: new sites of local anesthetic action and toxicity. Reg Anesth Pain Med 2005;30(3):260-274 (Pubitemid 40718909)
-
(2005)
Regional Anesthesia and Pain Medicine
, vol.30
, Issue.3
, pp. 260-274
-
-
Kindler, C.H.1
Yost, C.S.2
-
131
-
-
5644275478
-
2P channels and their role in general anaesthesia and neuroprotection
-
DOI 10.1016/j.tips.2004.09.003, PII S0165614704002536
-
Franks NP, Honoré E. The TREK K2P channels and their role in general anaesthesia and neuroprotection. Trends Pharmacol Sci 2004;25(11):601-608 (Pubitemid 39371151)
-
(2004)
Trends in Pharmacological Sciences
, vol.25
, Issue.11
, pp. 601-608
-
-
Franks, N.P.1
Honore, E.2
-
132
-
-
33746379873
-
Zinc and copper: Pharmacological probes and endogenous modulators of neuronal excitability
-
DOI 10.1016/j.pharmthera.2005.11.004, PII S0163725805002664
-
Mathie A, Sutton GL, Clarke CE, Veale EL. Zinc and copper: pharmacological probes and endogenous modulators of neuronal excitability. Pharmacol Ther 2006;111(3):567-583 (Pubitemid 44118429)
-
(2006)
Pharmacology and Therapeutics
, vol.111
, Issue.3
, pp. 567-583
-
-
Mathie, A.1
Sutton, G.L.2
Clarke, C.E.3
Veale, E.L.4
-
133
-
-
34547563267
-
+ channels
-
DOI 10.1161/CIRCRESAHA.107.157412, PII 0000301220070720000004
-
Bryan RM Jr, Joseph BK, Lloyd E, Rusch NJ. Starring TREK-1: the next generation of vascular K+ channels. Circ Res 2007;101:119-121 (Pubitemid 47196578)
-
(2007)
Circulation Research
, vol.101
, Issue.2
, pp. 119-121
-
-
Bryan Jr., R.M.1
Joseph, B.K.2
Lloyd, E.3
Rusch, N.J.4
-
134
-
-
33750605037
-
+ channels in determining pulmonary vascular tone, oxygen sensing, cell proliferation, and apoptosis: Implications in hypoxic pulmonary vasoconstriction and pulmonary arterial hypertension
-
DOI 10.1080/10739680600930222, PII W242N78126W69040
-
Moudgil R, Michelakis ED, Archer SL. The role of K+ channels in determining pulmonary vascular tone, oxygen sensing, cell proliferation, and apoptosis: implications in hypoxic pulmonary vasoconstriction and pulmonary arterial hypertension. Microcirculation 2006;13(8):615-632 (Pubitemid 44696118)
-
(2006)
Microcirculation
, vol.13
, Issue.8
, pp. 615-632
-
-
Moudgil, R.1
Michelakis, E.D.2
Archer, S.L.3
-
135
-
-
34347328112
-
Therapeutic potential of neuronal two-pore domain potassium-channel modulators
-
Mathie A, Veale EL. Therapeutic potential of neuronal two-pore domain potassium-channel modulators. Curr Opin Investig Drugs 2007;8(7):555-562 (Pubitemid 47016323)
-
(2007)
Current Opinion in Investigational Drugs
, vol.8
, Issue.7
, pp. 555-562
-
-
Mathie, A.1
Veale, E.L.2
-
136
-
-
3142699873
-
Regulation of recombinant human brain tandem P domain K+ channels by hypoxia: A role for O2 in the control of neuronal excitability?
-
Kemp PJ, Peers C, Lewis A, Miller P. Regulation of recombinant human brain tandem P domain K+ channels by hypoxia: a role for O2 in the control of neuronal excitability? J Cell Mol Med 2004;8(1):38-44
-
(2004)
J Cell Mol Med
, vol.8
, Issue.1
, pp. 38-44
-
-
Kemp, P.J.1
Peers, C.2
Lewis, A.3
Miller, P.4
-
137
-
-
67649625713
-
Pharmaceutical compositions comprising CB1 cannabinoid receptor antagonists and potassium channel openers for the treatment of diabetes mellitus type 1, obesity and related conditions
-
(in Chinese). CN101048153A
-
Harald FMG. Pharmaceutical compositions comprising CB1 cannabinoid receptor antagonists and potassium channel openers for the treatment of diabetes mellitus type 1, obesity and related conditions (in Chinese). CN101048153A; 2007
-
(2007)
-
-
Harald, F.M.G.1
-
138
-
-
67649616748
-
Salts of potassium ATP channel openers and uses thereof
-
EP1968601A2
-
Cowen NM, Kashkin KB, Yamout KA. Salts of potassium ATP channel openers and uses thereof. EP1968601A2; 2008
-
(2008)
-
-
Cowen, N.M.1
Kashkin, K.B.2
Yamout, K.A.3
-
139
-
-
67649619738
-
Pharmaceutical formulations of potassium ATP channels openers and uses thereof
-
JP2008510835T
-
Cowen NM, Kashkin KB. Pharmaceutical formulations of potassium ATP channels openers and uses thereof. JP2008510835T; 2008
-
(2008)
-
-
Cowen, N.M.1
Kashkin, K.B.2
-
140
-
-
67649628636
-
Method for decreasing blood glucose levels
-
US2007231273A1
-
Wu G. Method for decreasing blood glucose levels. US2007231273A1; 2007
-
(2007)
-
-
Wu, G.1
-
141
-
-
67649595698
-
Compounds for the treatment of an acute injury to the central nervous system
-
JP2008503548T
-
Gehenne JNM, Allue M, Pugliese M. Compounds for the treatment of an acute injury to the central nervous system. JP2008503548T; 2008
-
(2008)
-
-
Gehenne, J.N.M.1
Allue, M.2
Pugliese, M.3
-
143
-
-
67649598777
-
Therapeutic agents for overactive bladder
-
US2008033018A1
-
Horie S, Saito K, Ishizuka N. Therapeutic agents for overactive bladder. US2008033018A1; 2008
-
(2008)
-
-
Horie, S.1
Saito, K.2
Ishizuka, N.3
-
144
-
-
67649610830
-
Novel coumarin derivatives as ion channel openers
-
US20070037877A1
-
Jain N, Sui Z. Novel coumarin derivatives as ion channel openers. US20070037877A1; 2007;
-
(2007)
-
-
Jain, N.1
Sui, Z.2
-
145
-
-
67649580664
-
Novel coumarin derivatives as ion channel openers
-
JP2008528495T
-
Sui Z. Novel coumarin derivatives as ion channel openers. JP2008528495T; 2008
-
(2008)
-
-
Sui, Z.1
-
146
-
-
67649592623
-
Novel pyridine derivatives as potassium channel openers
-
JP2008531592T
-
Jain N, Xu J, Sui Z. Novel pyridine derivatives as potassium channel openers. JP2008531592T; 2008
-
(2008)
-
-
Jain, N.1
Xu, J.2
Sui, Z.3
-
147
-
-
67649592623
-
Novel quinoline derivatives as potassium ion channel openers
-
JP2008531590T
-
Jain N, Xu J, Sui Z. Novel quinoline derivatives as potassium ion channel openers. JP2008531590T; 2008
-
(2008)
-
-
Jain, N.1
Xu, J.2
Sui, Z.3
-
148
-
-
67649631698
-
Novel benzopyran derivatives as potassium channel openers
-
US2007072832A1
-
Zhang X, Li X, Sui Z. Novel benzopyran derivatives as potassium channel openers. US2007072832A1; 2007
-
(2007)
-
-
Zhang, X.1
Li, X.2
Sui, Z.3
-
149
-
-
67649631698
-
Novel benzopyran derivatives as potassium channel openers
-
EP1937669A1
-
Zhang X, Li X, Sui Z. Novel benzopyran derivatives as potassium channel openers. EP1937669A1; 2008
-
(2008)
-
-
Zhang, X.1
Li, X.2
Sui, Z.3
-
150
-
-
67649586798
-
Derivative of new benzothiadiazines, preparation method and usage
-
(in Chinese). CN101092405A
-
Hai W, Yonglin Y, Junhua J. Derivative of new benzothiadiazines, preparation method and usage (in Chinese). CN101092405A; 2007
-
(2007)
-
-
Hai, W.1
Yonglin, Y.2
Junhua, J.3
-
151
-
-
67649592638
-
Treatment of migraine and headaches
-
WO2007009462
-
Olesen IJ, Olesen J. Treatment of migraine and headaches. WO2007009462; 2007
-
(2007)
-
-
Olesen, I.J.1
Olesen, J.2
-
152
-
-
67649625693
-
Diphenylurea derivatives useful as potassium channel activators
-
JP2008524158T
-
Dahl BH, Christophersen P, Demnitz J. Diphenylurea derivatives useful as potassium channel activators. JP2008524158T; 2008
-
(2008)
-
-
Dahl, B.H.1
Christophersen, P.2
Demnitz, J.3
-
153
-
-
67649598778
-
Piperidinesulfonylureas and -thioureas, their preparation, their use and pharmaceutical compositions comprising them
-
US2008033016A1
-
Hachtel S, Englert HC, Gerlach U, et al. Piperidinesulfonylureas and -thioureas, their preparation, their use and pharmaceutical compositions comprising them. US2008033016A1; 2008
-
(2008)
-
-
Hachtel, S.1
Englert, H.C.2
Gerlach, U.3
-
154
-
-
67649574397
-
Piperidinesulfonylureas and -thioureas, their preparation, their use and pharmaceutical compositions comprising them
-
JP2008524132T; (in German)
-
Knieps S, Englert HC, Gerlach U, et al. Piperidinesulfonylureas and -thioureas, their preparation, their use and pharmaceutical compositions comprising them. JP2008524132T; 2008 (in German)
-
(2008)
-
-
Knieps, S.1
Englert, H.C.2
Gerlach, U.3
-
155
-
-
67649592634
-
Use of CBX cannabinoid receptor modulators as potassium channel modulators
-
AR060626A1
-
Antel J, Gregory PC, Lange JHM, et al. Use of CBX cannabinoid receptor modulators as potassium channel modulators. AR060626A1; 2008
-
(2008)
-
-
Antel, J.1
Gregory, P.C.2
Lange, J.H.M.3
-
156
-
-
67649586783
-
Pharmaceutical compositions comprising CBX cannabinoid receptor modulators
-
WO2007125048A1
-
Antel J, Gregory PC, Lange JHM, et al. Pharmaceutical compositions comprising CBX cannabinoid receptor modulators. WO2007125048A1; 2007
-
(2007)
-
-
Antel, J.1
Gregory, P.C.2
Lange, J.H.M.3
-
157
-
-
67649610831
-
Methods and compositions for treating and diagnosing diabetes
-
US7053180B2
-
Johnson JD, Palma JF, Schweitzer AC, Blume JE. Methods and compositions for treating and diagnosing diabetes. US7053180B2; 2006
-
(2006)
-
-
Johnson, J.D.1
Palma, J.F.2
Schweitzer, A.C.3
Blume, J.E.4
-
160
-
-
78650948609
-
Method for using potassium channel agonists for delivering a medicant to an abnormal brain region and/or a malignant tumor
-
JP2003523965T
-
Black KL, Ningaraj NS. Method for using potassium channel agonists for delivering a medicant to an abnormal brain region and/or a malignant tumor. JP2003523965T; 2003
-
(2003)
-
-
Black, K.L.1
Ningaraj, N.S.2
-
161
-
-
67649598791
-
Compounds for the treatment of inflammation of the central nervous system
-
JP2008503549T
-
Gehenne JNM, Rodriquez AMJ, Pugliese M. Compounds for the treatment of inflammation of the central nervous system. JP2008503549T; 2008
-
(2008)
-
-
Gehenne, J.N.M.1
Rodriquez, A.M.J.2
Pugliese, M.3
-
162
-
-
67649616746
-
Composition comprising a ATP channel inhibitor for use in the treatment of hemorrhagic shock
-
BR9710957A
-
Salzman AL, Szabo C. Composition comprising a ATP channel inhibitor for use in the treatment of hemorrhagic shock. BR9710957A; 2001
-
(2001)
-
-
Salzman, A.L.1
Szabo, C.2
-
163
-
-
67649589099
-
Compounds produced by a strain of Streptomyces exfoliates
-
US5332574A
-
Sugawara K, Tomita K, Kozlowski MR, Sawada Y. Compounds produced by a strain of Streptomyces exfoliates. US5332574A; 1994
-
(1994)
-
-
Sugawara, K.1
Tomita, K.2
Kozlowski, M.R.3
Sawada, Y.4
-
164
-
-
67649598786
-
Myocardial cell apoptosis inhibitors
-
EP1421952A4
-
Yokota M. Myocardial cell apoptosis inhibitors. EP1421952A4; 2005
-
(2005)
-
-
Yokota, M.1
-
165
-
-
67649586781
-
Pharmaceutical composition for preventing and treating sexual dysfunction
-
AR026506A1
-
Kim JJ, Moon DG. Pharmaceutical composition for preventing and treating sexual dysfunction. AR026506A1; 2003
-
(2003)
-
-
Kim, J.J.1
Moon, D.G.2
-
166
-
-
67649610839
-
Methods of protecting neuronal function
-
US6313112
-
Busija DW. Methods of protecting neuronal function. US6313112; 2001;
-
(2001)
-
-
Busija, D.W.1
-
167
-
-
67649610839
-
Methods of protecting neuronal function
-
US6313112B1
-
Busija D. Methods of protecting neuronal function. US6313112B1; 2001;
-
(2001)
-
-
Busija, D.1
-
170
-
-
67649631699
-
Intranasal administration of hypothalamic ATP-sensitive potassium channels
-
US2007026079A1
-
Herlands L, Rossetti L, Pocai A. Intranasal administration of hypothalamic ATP-sensitive potassium channels. US2007026079A1; 2007
-
(2007)
-
-
Herlands, L.1
Rossetti, L.2
Pocai, A.3
-
171
-
-
67649625707
-
Intranasal administration of hypothalamic ATP-sensitive potassium channels
-
WO2006088875A2
-
Herlands L, Pocai A, Rossetti L. Intranasal administration of hypothalamic ATP-sensitive potassium channels. WO2006088875A2; 2006
-
(2006)
-
-
Herlands, L.1
Pocai, A.2
Rossetti, L.3
-
172
-
-
67649592641
-
Diagnosing and treating potassium channel defects
-
US2006263805A1
-
Terzic A, Olson TM, Kane GC. Diagnosing and treating potassium channel defects. US2006263805A1; 2006
-
(2006)
-
-
Terzic, A.1
Olson, T.M.2
Kane, G.C.3
-
174
-
-
67649595709
-
New application of genetically modified animal
-
JP2006149380A
-
Kiyono S, Miki T, Oyama K. New application of genetically modified animal. JP2006149380A; 2006
-
(2006)
-
-
Kiyono, S.1
Miki, T.2
Oyama, K.3
-
175
-
-
67649607621
-
ATP-sensitive potassium channel gene (Kir6.2/BIR)-deficient animals
-
DE69928996T2
-
Susumu S, Takashi M, Junichi M. ATP-sensitive potassium channel gene (Kir6.2/BIR)-deficient animals. DE69928996T2; 2006
-
(2006)
-
-
Susumu, S.1
Takashi, M.2
Junichi, M.3
-
176
-
-
67649595707
-
Diagnostics and therapeutics for diseases associated with potassium channels, subfamily K, member 1 (KCNK1)
-
WO2005054864A3
-
Golz S, Brueggemeier ULF, Geerts A. Diagnostics and therapeutics for diseases associated with potassium channels, subfamily K, member 1 (KCNK1). WO2005054864A3; 2005
-
(2005)
-
-
Golz, S.1
Brueggemeier, U.L.F.2
Geerts, A.3
-
177
-
-
67649622845
-
Novel potassium channel molecules and uses therefore
-
WO0132872A3
-
Curtis RAJ, Silos-Santiago I. Novel potassium channel molecules and uses therefore. WO0132872A3; 2001
-
(2001)
-
-
Curtis, R.A.J.1
Silos-Santiago, I.2
-
178
-
-
67649580676
-
Nucleic acids and polypeptides of invertebrate TWIK channels and methods of use
-
WO0109301A3
-
Francis-Lang HL, Gillett LA, Margolis JS, et al. Nucleic acids and polypeptides of invertebrate TWIK channels and methods of use. WO0109301A3; 2001
-
(2001)
-
-
Francis-Lang, H.L.1
Gillett, L.A.2
Margolis, J.S.3
-
179
-
-
67649583703
-
Nucleic acids and polypeptides of invertebrate TWIK channels and methods of use
-
US6703491B1
-
Buchman AR, Burks C, Francis-Lang HL, et al. Nucleic acids and polypeptides of invertebrate TWIK channels and methods of use. US6703491B1; 2004
-
(2004)
-
-
Buchman, A.R.1
Burks, C.2
Francis-Lang, H.L.3
-
180
-
-
67649574407
-
Isolated TWIK-1 potassium channel proteins
-
US7067625B1
-
Lesage F, Guillemare E, Fink M, et al. Isolated TWIK-1 potassium channel proteins. US7067625B1; 2006
-
(2006)
-
-
Lesage, F.1
Guillemare, E.2
Fink, M.3
-
181
-
-
67649613218
-
Nucleic acid encoding new potassium channel designated TWIK-1
-
EP0799889B1
-
Lesage F, Guillemare E, Fink M, et al. Nucleic acid encoding new potassium channel designated TWIK-1. EP0799889B1; 2004
-
(2004)
-
-
Lesage, F.1
Guillemare, E.2
Fink, M.3
-
182
-
-
67649622849
-
Modulators of the potassium channels twik-1, task-1, gorl1, sk2 pr pcn1, used to treat arrhythmia, coronary heart disease or hypertension
-
US2006183665A1
-
Ellinghaus P, Munter K. Modulators of the potassium channels twik-1, task-1, gorl1, sk2 pr pcn1, used to treat arrhythmia, coronary heart disease or hypertension. US2006183665A1; 2006
-
(2006)
-
-
Ellinghaus, P.1
Munter, K.2
-
183
-
-
67649583704
-
TREK-1 like two pore potassium channels
-
JP2002511233T
-
Meadows HJ, Chapman CG. TREK-1 like two pore potassium channels. JP2002511233T; 2002
-
(2002)
-
-
Meadows, H.J.1
Chapman, C.G.2
-
184
-
-
67649583704
-
TREK-1 like two pore potassium channels
-
EP1051485A1
-
Meadows HJ, Chapman CG. TREK-1 like two pore potassium channels. EP1051485A1; 2000
-
(2000)
-
-
Meadows, H.J.1
Chapman, C.G.2
-
186
-
-
67649625711
-
Diagnostics and therapeutics for diseases associated with two-pore domain potassium channel (KCN2)
-
WO2005054866A3
-
Golz S, Brueggemeier UFL, Geerts A. Diagnostics and therapeutics for diseases associated with two-pore domain potassium channel (KCN2). WO2005054866A3; 2005
-
(2005)
-
-
Golz, S.1
Brueggemeier, U.F.L.2
Geerts, A.3
-
187
-
-
67649613215
-
A method for the identification of anesthetics
-
JP2002536017T
-
Lazdunski M, Honoré E, Lesage F, et al. A method for the identification of anesthetics. JP2002536017T; 2002
-
(2002)
-
-
Lazdunski, M.1
Honoré, E.2
Lesage, F.3
-
188
-
-
67649607620
-
Potassium channels in human heart
-
WO2006066334A1
-
Saint DA, Zhu H. Potassium channels in human heart. WO2006066334A1; 2006
-
(2006)
-
-
Saint, D.A.1
Zhu, H.2
-
189
-
-
67649577117
-
Method for the identification of anesthetics
-
US7112403B1
-
Patel AJ, Honoré E, Lesage F, et al. Method for the identification of anesthetics. US7112403B1; 2006
-
(2006)
-
-
Patel, A.J.1
Honoré, E.2
Lesage, F.3
-
190
-
-
67649604705
-
Method of treating a condition associated with phosphorylation of TASK-1
-
WO2008013988A9
-
Feinmark SJ, Robinson RB. Method of treating a condition associated with phosphorylation of TASK-1. WO2008013988A9; 2008
-
(2008)
-
-
Feinmark, S.J.1
Robinson, R.B.2
-
191
-
-
67649604708
-
Method of treating a condition associated with phosphorylation of TASK-1
-
WO2007014347A9
-
Robinson RB, Feinmark SJ. Method of treating a condition associated with phosphorylation of TASK-1. WO2007014347A9; 2007
-
(2007)
-
-
Robinson, R.B.1
Feinmark, S.J.2
-
192
-
-
67649595707
-
Diagnostics and therapeutics for diseases associated with potassium channel, subfamily K, member 3 (KCNK3)
-
WO2005052586A3
-
Golz S, Brueggemeier ULF, Geerts A. Diagnostics and therapeutics for diseases associated with potassium channel, subfamily K, member 3 (KCNK3). WO2005052586A3; 2005
-
(2005)
-
-
Golz, S.1
Brueggemeier, U.L.F.2
Geerts, A.3
-
193
-
-
67649622844
-
Family of mammalian potassium channels, their cloning and their use, especially for the screening of drugs
-
US6309855B1
-
Duprat F, Lesage F, Fink M, Lazdunski M. Family of mammalian potassium channels, their cloning and their use, especially for the screening of drugs. US6309855B1; 2001
-
(2001)
-
-
Duprat, F.1
Lesage, F.2
Fink, M.3
Lazdunski, M.4
-
194
-
-
67649631700
-
Genes associated with COPD
-
US2008108079A1
-
Chissoe S. Genes associated with COPD. US2008108079A1; 2008
-
(2008)
-
-
Chissoe, S.1
-
195
-
-
67649604707
-
Method for screening substances capable of modulating the activity of a TRAAK potassium channel
-
US2006024729A1
-
Honoré E, Fink M, Lazdunski M, et al. Method for screening substances capable of modulating the activity of a TRAAK potassium channel. US2006024729A1; 2006
-
(2006)
-
-
Honoré, E.1
Fink, M.2
Lazdunski, M.3
-
196
-
-
67649616739
-
Family of mechanosensitive human channels activated by polyunsaturated fatty acids
-
US2003049697A1
-
Lazdunski M, Lesage F, Maingret F. Family of mechanosensitive human channels activated by polyunsaturated fatty acids. US2003049697A1; 2003
-
(2003)
-
-
Lazdunski, M.1
Lesage, F.2
Maingret, F.3
-
197
-
-
67649595707
-
Diagnostics and therapeutics for diseases associated with potassium channels, subfamily K, member 4 (KCNK4)
-
WO2005052574A3
-
Golz S, Brueggemeier ULF, Geerts A. Diagnostics and therapeutics for diseases associated with potassium channels, subfamily K, member 4 (KCNK4). WO2005052574A3; 2005
-
(2005)
-
-
Golz, S.1
Brueggemeier, U.L.F.2
Geerts, A.3
-
198
-
-
67649583700
-
Human potassium channel (h-TRAAK)
-
US6426197B1
-
Chapman CG, Duckworth DM. Human potassium channel (h-TRAAK). US6426197B1; 2002
-
(2002)
-
-
Chapman, C.G.1
Duckworth, D.M.2
-
199
-
-
67649616743
-
Polynucleotides encoding a human potassium channel
-
US6426197B1
-
Duckworth DM, Chapman CG. Polynucleotides encoding a human potassium channel. US6426197B1; 2002
-
(2002)
-
-
Duckworth, D.M.1
Chapman, C.G.2
-
200
-
-
67649598788
-
Potassium channels, nucleotide sequences encoding them, and methods of using same
-
US2006110792A1
-
Pausch MH, Price LA. Potassium channels, nucleotide sequences encoding them, and methods of using same. US2006110792A1; 2006
-
(2006)
-
-
Pausch, M.H.1
Price, L.A.2
-
201
-
-
67649613217
-
Potassium channels, nucleotide sequences encoding them, and methods of using
-
US2003165806A1
-
Pausch MH. Potassium channels, nucleotide sequences encoding them, and methods of using. US2003165806A1; 2003
-
(2003)
-
-
Pausch, M.H.1
-
202
-
-
67649574398
-
Method for identifying antidepressants, based on ability of test compounds to inhibit potassium channels that contain two pore domains, also use of antibodies against these channels for treating depression
-
FR2850397A1
-
Lazdunski M, Guy N. Method for identifying antidepressants, based on ability of test compounds to inhibit potassium channels that contain two pore domains, also use of antibodies against these channels for treating depression. FR2850397A1; 2004
-
(2004)
-
-
Lazdunski, M.1
Guy, N.2
-
203
-
-
67649583697
-
Novel TWIK-6, TWIK-7, IC23927, TWIK-8, IC47611, IC46715, HNMDA-1, TWIK-9, alpha2delta-4, 8099, 46455, 54414, 53763, 97076, 97102, 44181, 67084FI and 67084alt molecules and uses therefore
-
US2008032289A1
-
Curtis RAJ, Glucksmann MA, Silos-Santiago I. Novel TWIK-6, TWIK-7, IC23927, TWIK-8, IC47611, IC46715, HNMDA-1, TWIK-9, alpha2delta-4, 8099, 46455, 54414, 53763, 97076, 97102, 44181, 67084FI and 67084alt molecules and uses therefore. US2008032289A1; 2008
-
(2008)
-
-
Curtis, R.A.J.1
Glucksmann, M.A.2
Silos-Santiago, I.3
-
204
-
-
67649628633
-
56115, a novel human TWIK potassium channel and uses therefore
-
WO0226983A3
-
Curtis RAJ. 56115, a novel human TWIK potassium channel and uses therefore. WO0226983A3; 2002
-
(2002)
-
-
Curtis, R.A.J.1
-
205
-
-
67649580674
-
TWIK-5 potassium polypeptides and uses therefore
-
US6664373B1
-
Curtis RAJ, Silos-Santiago I. TWIK-5 potassium polypeptides and uses therefore. US6664373B1; 2003
-
(2003)
-
-
Curtis, R.A.J.1
Silos-Santiago, I.2
-
206
-
-
67649580674
-
TWIK-5 potassium nucleic acids and uses therefore
-
US6670149B1
-
Curtis RAJ. TWIK-5 potassium nucleic acids and uses therefore. US6670149B1; 2003
-
(2003)
-
-
Curtis, R.A.J.1
-
207
-
-
67649613214
-
12303, a novel human TWIK molecule and uses therefore
-
DE60124910T2
-
Glucksmann A. 12303, a novel human TWIK molecule and uses therefore. DE60124910T2; 2007
-
(2007)
-
-
Glucksmann, A.1
-
208
-
-
67649592640
-
Two P domains potassium channel
-
WO9936529A2
-
Partiseti M. Two P domains potassium channel. WO9936529A2; 1999
-
(1999)
-
-
Partiseti, M.1
-
209
-
-
67649622833
-
Human TREK2, a stretch- and arachidonic acid-sensitive K+ channel activated by inhalational anesthetics and riluzole
-
US6962976B2
-
Lazdunski M, Lesage F, Romey G. Human TREK2, a stretch- and arachidonic acid-sensitive K+ channel activated by inhalational anesthetics and riluzole. US6962976B2; 2005
-
(2005)
-
-
Lazdunski, M.1
Lesage, F.2
Romey, G.3
-
210
-
-
67649601189
-
Human TREK2 polypeptides
-
GB2365010A
-
Chapman CG, Duckworth DM. Human TREK2 polypeptides. GB2365010A; 2002.
-
(2002)
-
-
Chapman, C.G.1
Duckworth, D.M.2
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