Combined antisense and pharmacological approaches implicate hTASK as an airway O2 sensing K+ channel

Journal of Biological Chemistry

Volumn 276, Issue 28, 2001, Pages 26499-26508

  Hartness, Matthew E ^a   Lewis, Anthony ^a   Searle, Gavin J ^a   O'Kelly, Ita ^a   Peers, Chris ^a   Kemp, Paul J ^a  

^a UNIVERSITY OF LEEDS   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; NERVE PROTEIN; OXYGEN; POTASSIUM CHANNEL; POTASSIUM CHANNEL SUBFAMILY K MEMBER 3; TANDEM PORE DOMAIN POTASSIUM CHANNEL; ANTISENSE OLIGODEOXYNUCLEOTIDE; ARACHIDONIC ACID; DITHIOTHREITOL; FREE RADICAL; HALOTHANE; HYDROGEN PEROXIDE; LIPOSOME; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; TETRYLAMMONIUM;

ANOXIA; ARTICLE; DRUG EFFECT; GENETICS; HUMAN; METABOLISM; RESPIRATORY SYSTEM; CELL MEMBRANE DEPOLARIZATION; CONTROLLED STUDY; HUMAN CELL; HYPOXIA; LUNG CARCINOMA; NEUROEPITHELIUM; NUCLEOTIDE SEQUENCE; PH; POTASSIUM CURRENT; PRIORITY JOURNAL; RESPIRATORY EPITHELIUM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANOXIA; HUMANS; NERVE TISSUE PROTEINS; OLIGONUCLEOTIDES, ANTISENSE; OXYGEN; POTASSIUM CHANNELS; POTASSIUM CHANNELS, TANDEM PORE DOMAIN; RESPIRATORY SYSTEM;

CELLS; ENZYME KINETICS; OXYGEN; PROTEINS;

DEPOLARIZATIONS;

BIOCHEMISTRY;

EID: 0035854748     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.m010357200     Document Type: Article

References (16)

1. Peers, C. (1997) Trends Pharmacol. Sci. 18, 405-408
2. Lopez-Barneo, J. (1996) Trends Neurosci. 19, 435-440
3. Cutz, E., and Jackson, A. (1999) Respir. Physiol. 115, 201-214
4. Youngson, C., Nurse, C., Yeger, H., and Cutz, E. (1993) Nature 365, 153-155
5. Fu, X. W., Wang, D., Nurse, C., Dinauer, II. C., and Cutz, E. (2000) Proc. Natl. Acac. Sci. U. S. A. 97, 4374-4379
6. O'Kelly, L, Lewis, A., Peers, C., and Kemp, P. J. (2000) J. Biol. Chem. 275, 7684-7692
7. O'Kelly, I., Stephens, R. H., Peers, C., and Kemp, P. J. (1999) Am. J. Physiol. 276, L96-L104
8. O'Kelly, I., Peers, C., and Kemp, P. J. (1998) Am. J. Physiol. 275, L709-L716
9. Gazdar, A, F., Helman, L. J., Israel, M. A., Russell, E. K, Linnoila, R. I., Mulshine, J. L., Schuller, H. M., and Park, J. G. (1988) Cancer Res. 48, 4078-4082
10. Wang, D., Youngson, C., Wong, V., Yeger, H., Dinauer, M. C., Veg̀a-Saenz de Miera, E., Rudy, B., and Cutz, E. (1996) Proc. Nail. Aead. Sci. U. S. A. 93, 13182-13187
11. Lauweryns, J. M., and Cokeleare, M. (1973) Z. Zellforsch. Mikrosk. Anat. 145, 521-540
12. Buckler, K. J., Williams, B. A., and Honore, E. (2000) J. Physiol. (Land.) 525, 135-142
13. Peers, C. (1990) Neurosci. Lett. 119, 253-256
14. Duprat, F., Lesage, F., Fink, M., Reyes, R., Heurteaux, C., and Lazdunski, M. (1997) EMBO J. 16, 5464-5471
15. Rychkov, G. Y., Astill, D. S., Bennetts, B., Hughes, B. P., Bretag, A. H., and Roberts, M. L. (1997) J. Physiol. (Land.) 501, 355-362
16. Stengl, M., Carmeliet, E., Mubagwa, K., and Flameng, W. (1998) J. Physiol. (Land.) 511, 827-836