Neuronal two-pore-domain potassium channels and their regulation by G protein-coupled receptors

Journal of Physiology

Volumn 578, Issue 2, 2007, Pages 377-385

  Mathie, Alistair ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CALCINEURIN; G PROTEIN COUPLED RECEPTOR; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE; PHOSPHOPROTEIN PHOSPHATASE; POTASSIUM CHANNEL; CYCLIC AMP; DIACYLGLYCEROL; G PROTEIN G ALPHA I; G PROTEIN G ALPHA Q; G PROTEIN G ALPHA S; GUANINE NUCLEOTIDE BINDING PROTEIN; PHOSPHOLIPASE C; PROTEIN KINASE C; TWO PORE DOMAIN POTASSIUM CHANNEL; TWO PORE DOMAIN POTASSIUM CHANNEL SUBFAMILY TASK; TWO PORE DOMAIN POTASSIUM CHANNEL SUBFAMILY TRESK; UNCLASSIFIED DRUG;

NERVE CELL EXCITABILITY; NERVOUS SYSTEM; NONHUMAN; POTASSIUM CURRENT; PRIORITY JOURNAL; PROTEIN DEPHOSPHORYLATION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FAMILY; REGULATORY MECHANISM; REVIEW; CALCIUM CELL LEVEL; ENZYME ACTIVATION; HUMAN; NERVE CELL; POTASSIUM CONDUCTANCE; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; STANDING OUTWARD POTASSIUM CURRENT;

ANIMALS; GTP-BINDING PROTEIN ALPHA SUBUNITS, GQ-G11; HUMANS; ION CHANNEL GATING; MODELS, BIOLOGICAL; NEURONS; POTASSIUM CHANNELS; POTASSIUM CHANNELS, TANDEM PORE DOMAIN; RECEPTORS, G-PROTEIN-COUPLED;

EID: 33846198311     PISSN: 00223751     EISSN: 14697793     Source Type: Journal    
DOI: 10.1113/jphysiol.2006.121582     Document Type: Review

References (71)

1. TREK in cardiomyocytes. J Biol Chem 275, 39110-39116.
2. Aller MI, Veale EL, Linden AM, Sandu C, Schwaninger M, Evans LJ, Korpi ER, Mathie A, Wisden W & Brickley SG (2005). Modifying the subunit composition of TASK channels alters the modulation of a leak conductance in cerebellar granule neurons. J Neurosci 25, 11455-11467.
3. + channel family. J Biol Chem 275, 17412-17419.
4. + channel TASK-1 contributes to arrhythmogenic effects of platelet-activating factor. Am J Physiol Heart Circ Physiol 282, H2024-H2030.
5. + channel expressed in brainstem respiratory neurons. Respir Physiol 129, 159-174.
6. Beech DJ, Bernheim L, Mathie A & Hille B (1991). Intracellular Ca buffers disrupt muscarinic suppression of Ca-current and M-current in rat sympathetic neurons. Proc Natl Acad Sci U S A 88, 652-656.
7. + (TASK) channels containing TASK-1 (KCNK3) and TASK-3 (KCNK9) subunits. J Neurosci 24, 6693-6702.
8. + channel, TASK-1, inducing repolarization abnormalities in cardiac ventricular myocytes. J Biol Chem 279, 33154-33160.
9. Bockenhauer D, Zilberberg N & Goldstein SA (2001). KCNK2: Reversible conversion of a hippocampal potassium leak into a voltage-dependent channel. Nat Neurosci 4, 486-491.
10. K(SO) in neonatal rat cerebellar granule cells. J Physiol 529, 321-331.
11. Brickley SG, Revilla V, Cull-Candy SG, Wisden W & Farrant M (2001). Adaptive regulation of neuronal excitability by a voltage-independent potassium conductance. Nature 409, 88-92.
12. Buckler KJ, Williams BA & Honore E (2000). An oxygen-, acid- and anaesthetic-sensitive TASK-like background potassium channel in rat arterial chemoreceptor cells. J Physiol 525, 135-142.
13. Bushell T, Clarke C, Mathie A & Robertson B (2002). Pharmacological characterisation of a non-inactivating outward current observed in mouse cerebellar Purkinje neurones. Br J Pharmacol 135, 705-712.
14. 2P 2.1 by mGlu4: A molecular and pharmacological study. Proc Phys Soc 3, C13.
15. + channels. EMBO J 22, 5403-5411.
16. + channel TREK-1. EMBO J 24, 44-53.
17. Chen X, Talley EM, Patel N, Gomis A, McIntire WE, Dong B, Viana F, Garrison JC & Bayliss DA (2006). Inhibition of a background potassium channel by Gq protein α-subunits. Proc Natl Acad Sci U S A 103, 3422-3427.
18. SO, by zinc. J Physiol 560, 51-62.
19. 2+ stores in rat sympathetic neurons. Proc Natl Acad Sci U S A 95, 7151-7156.
20. Czirjak G & Enyedi P (2002). Formation of functional heterodimers between the TASK-1 and TASK-3 two-pore domain potassium channel subunits. J Biol Chem 277, 5426-5432.
21. + channel, TRESK. J Biol Chem 281, 14677-14682.
22. + channel) is expressed in glomerulosa cells of rat adrenal cortex and inhibited by angiotensin II. Mol Endocrinol 14, 863-874.
23. Czirjak G, Petheo GL, Spat A & Enyedi P (2001). Inhibition of TASK-1 potassium channel by phospholipase C. Am J Physiol Cell Physiol 281, C700-C708.
24. + channel, TRESK, is activated by the cytoplasmic calcium signal through calcineurin. J Biol Chem 279, 18550-18558.
25. Delmas P & Brown DA (2005). Pathways modulating neural KCNQ/M (Kv7) potassium channels. Nat Rev Neurosci 6, 850-862.
26. + channel to sense external pH variations near physiological pH. EMBO J 16, 5464-5471.
27. Enkvetchakul D, Jeliazkova I & Nichols CG (2005). Direct modulation of Kir channel gating by membrane phosphatidylinositol 4,5-bisphosphate. J Biol Chem 280, 35785-35788.
28. 2+ - and ATP hydrolysis-dependent mechanisms. J Biol Chem 280, 30814-30828.
29. + channel. EMBO J 15, 6854-6862.
30. Goldstein SAN, Bockenhauer D, O'Kelly I & Zilberberg N (2001). Potassium leak channels and the KCNK family of two-P-domain subunits. Nat Rev Neurosci 2, 175-184.
31. Han J, Truell J, Gnatenco C & Kim D (2002). Characterization of four types of background potassium channels in rat cerebellar granule neurons. J Physiol 542, 431-444.
32. Heurteaux C, Lucas G, Guy N, El Yacoubi M, Thummler S, Peng XD, Noble F, Blondeau N, Widmann C, Borsotto M, Gobbi G, Vaugeois JM, Debonnel G & Lazdunski M (2006). Deletion of the background potassium channel TREK-1 results in a depression-resistant phenotype. Nat Neurosci 9, 1134-1141.
33. 2 with ion channels and transporters. Sci STKE 2001, RE19.
34. Hille B (1992). G protein-coupled mechanisms and nervous signaling. Neuron 9, 187-195.
35. + channels mediate effects of 5-HT and extracellular pH in rat dorsal vagal neurones in vitro. J Physiol 568, 145-154.
36. 2 and its stabilization by Gβγ. Nature 391, 803-806.
37. 3 muscarinic receptor. Am J Physiol Cell Physiol 291, C649-C656.
38. Kang D, Han J, Talley EM, Bayliss DA & Kim D (2004 a). Functional expression of TASK-1/TASK-3 heteromers in cerebellar granule cells. J Physiol 554, 64-77.
39. + channels in dorsal root ganglion neurons. Am J Physiol Cell Physiol 291, C138-C146.
40. + channel family. J Biol Chem 279, 28063-28070.
41. Kettunen P, Hess D & El Manira A (2003). mGluR1, but not mGluR5, mediates depolarization of spinal cord neurons by blocking a leak current. J Neurophysiol 90, 2341-2348.
42. + channel family. J Biol Chem 275, 9340-9347.
43. Koh SD, Monaghan K, Sergeant GP, Ro S, Walker RL, Sanders KM & Horowitz B (2001). TREK-1 regulation by nitric oxide and cGMP-dependent protein kinase. An essential role in smooth muscle inhibitory neurotransmission. J Biol Chem 276, 44338-44346.
44. + conductance regulates neonatal rat facial motoneuron excitability in vitro. Eur J Neurosci 21, 679-691.
45. + channels. J Biol Chem 278, 32068-32076.
46. Leonoudakis D, Gray AT, Winegar BD, Kindler CH, Harada M, Taylor DM, Chavez RA, Forsayeth JR & Yost CS (1998). An open rectifier potassium channel with two pore domains in tandem cloned from rat cerebellum. J Neurosci 18, 868-877.
47. Lesage F (2003). Pharmacology of neuronal background potassium channels. Neuropharmacol 44, 1-7.
48. q protein-coupled receptors. J Biol Chem 275, 28398-28405.
49. Lopes CM, Gallagher PG, Buck ME, Butler MH & Goldstein SA (2000). Proton block and voltage gating are potassium-dependent in the cardiac leak channel Kcnk3. J Biol Chem 275, 16969-16978.
50. + channels. J Physiol 564, 117-129.
51. + channel. Biochem Biophys Res Commun 292, 339-346.
52. Mathie A, Clarke CE, Ranatunga KM & Veale EL (2003). What are the roles of the many different types of potassium channel expressed in cerebellar granule cells? Cerebellum 2, 11-25.
53. Meadows HJ & Randall AD (2001). Functional characterisation of human TASK-3, an acid-sensitive two-pore domain potassium channel. Neuropharmacol 40, 551-559.
54. + channel 1 (TASK1) and TASK3 channels to the control of activity modes in thalamocortical neurons. J Neurosci 23, 6460-6469.
55. Millar JA, Barratt L, Southan AP, Page KM, Fyffe RE, Robertson B & Mathie A (2000). A functional role for the two-pore domain potassium channel TASK-1 in cerebellar granule neurons. Proc Natl Acad Sci U S A 97, 3614-3618.
56. Murbartian J, Lei Q, Sando JJ & Bayliss DA (2005). Sequential phosphorylation mediates receptor- and kinase-induced inhibition of TREK-1 background potassium channels. J Biol Chem 280, 30175-30184.
57. + channels-molecular sensors. Biochim Biophys Acta 1566, 152-161.
58. + channel. EMBO J 17, 4283-4290.
59. + current in the adult turtle. J Physiol 548, 485-492.
60. + channel. An extracellular histidine as pH sensor. J Biol Chem 275, 16650-16657.
61. + channel, TRESK, is localized in the spinal cord. J Biol Chem 278, 27406-27412.
62. h by an inhalational anaesthetic and neurotransmitters in rat brainstem motoneurones. J Physiol 541, 717-729.
63. Suh BC & Hille B (2005). Regulation of ion channels by phosphatidylinositol 4,5-bisphosphate. Curr Opin Neurobiol 15, 370-378.
64. Takayasu Y, Iino M, Furuya N & Ozawa S (2003). Muscarine-induced increase in frequency of spontaneous EPSCs in Purkinje cells in the vestibulo-cerebellum of the rat. J Neurosci 23, 6200-6208.
65. Talley EM & Bayliss DA (2002). Modulation of TASK-1 (Kcnk3) and TASK-3 (Kcnk9) potassium channels: Volatile anesthetics and neurotransmitters share a molecular site of action. J Biol Chem 277, 17733-17742.
66. + channel, is modulated by multiple neurotransmitters in motoneurons. Neuron 25, 399-410.
67. Talley EM, Solorzano G, Lei Q, Kim D & Bayliss DA (2001). CNS distribution of members of the two-pore-domain (KCNK) potassium channel family. J Neurosci 21, 7491-7505.
68. Veale EL, Sutton GL & Mathie A (2006). Inhibition of TASK3 two pore domain potassium channels following activation of protein kinase C. Proc Phys Soc 3 PC28.
69. + channels closely related to TASK-1. J Neurophysiol 86, 130-142.
70. + current sensitive to muscarinic receptor activation in rat cultured cerebellar granule neurons. J Physiol 491, 401-412.
71. + channels. Nat Neurosci 6, 811-818.