SUR, ABC proteins targeted by KATP channel openers

Journal of Molecular and Cellular Cardiology

Volumn 38, Issue 6, 2005, Pages 951-963

  Moreau, Christophe ^a   Prost, Anne Lise ^a   Dérand, Renaud ^a   Vivaudou, Michel ^a  

^a CEA GRENOBLE   (France)

Author keywords

ABC transporter; ATP sensitive K+ channels; Cromakalim; Diazoxide; K channel opener; Pinacidil; Sulfonylurea receptor

Indexed keywords

ABC TRANSPORTER; ADENOSINE TRIPHOSPHATASE; ANTIHYPERTENSIVE AGENT; CHIMERIC PROTEIN; CROMAKALIM; DIAZOXIDE; GLIBENCLAMIDE; INSULIN; INWARDLY RECTIFYING POTASSIUM CHANNEL SUBUNIT KIR6.2; MULTIDRUG RESISTANCE PROTEIN 1; PINACIDIL; POTASSIUM CHANNEL; POTASSIUM CHANNEL STIMULATING AGENT; SULFONYLUREA RECEPTOR;

CARBOXY TERMINAL SEQUENCE; CELL ULTRASTRUCTURE; CONFORMATIONAL TRANSITION; DRUG POTENCY; DRUG PROTEIN BINDING; DRUG RECEPTOR BINDING; ENZYME ACTIVITY; ENZYME SUBSTRATE; GENE STRUCTURE; INSULIN RELEASE; LIGAND BINDING; MOLECULAR PHYLOGENY; NONHUMAN; NUCLEOTIDE BINDING SITE; PATCH CLAMP; POINT MUTATION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FAMILY; PROTEIN STRUCTURE; PROTEIN TARGETING; RECEPTOR AFFINITY; REVIEW; SEQUENCE HOMOLOGY; STRUCTURE ANALYSIS;

ADENOSINE TRIPHOSPHATE; ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; CROMAKALIM; CYTOPLASM; DIAZOXIDE; DOWN-REGULATION; HUMANS; MODELS, BIOLOGICAL; PINACIDIL; POTASSIUM CHANNELS; POTASSIUM CHANNELS, INWARDLY RECTIFYING; PROTEIN BINDING; PROTEIN ISOFORMS; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, DRUG; UP-REGULATION;

EID: 15744370602     PISSN: 00222828     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.yjmcc.2004.11.030     Document Type: Review

References (120)

1. V.A. Selivanov, A.E. Alekseev, D.M. Hodgson, P.P. Dzeja, and A. Terzic Nucleotide-gated KATP channels integrated with creatine and adenylate kinases: amplification, tuning and sensing of energetic signals in the compartmentalized cellular environment Mol. Cell. Biochem. 256 2004 243 256
2. S.J.H. Ashcroft The beta-cell KATP channel J. Membr. Biol. 176 2000 187 206
3. M. Suzuki, N. Sasaki, T. Miki, N. Sakamoto, Y. OhmotoSekine, and M. Tamagawa Role of sarcolemmal KATP channels in cardioprotection against ischemia/reperfusion injury in mice J. Clin. Invest. 109 2002 509 516
4. L.V. Zingman, D.M. Hodgson, P.H. Bast, G.C. Kane, C. PerezTerzic, and R.J. Gumina Kir6.2 is required for adaptation to stress Proc. Natl. Acad. Sci. USA 99 2002 13278 13283
5. S. Seino, and T. Miki Physiological and pathophysiological roles of ATP-sensitive K+ channels Prog. Biophys. Mol. Biol. 81 2003 133 176
6. L. Aguilar-Bryan, C.G. Nichols, S.W. Wechsler, J.P. Clement, A.E. Boyd, and G. Gonzalez Cloning of the β cell high-affinity sulfonylurea receptor: a regulator of insulin secretion Science 268 1995 423 426
7. N. Inagaki, T. Gonoi, J.P. Clement, N. Namba, J. Inazawa, and G. Gonzalez Reconstitution of I-KATP: an inward rectifier subunit plus the sulfonylurea receptor Science 270 1995 1166 1170
8. H. Sakura, C. Ammala, P.A. Smith, F.M. Gribble, and F.M. Ashcroft Cloning and functional expression of the cDNA encoding a novel ATP-sensitive potassium channel subunit expressed in pancreatic beta-cells, brain, heart and skeletal muscle FEBS Lett. 377 1995 338 344
9. C. Ammala, A. Moorhouse, and F.M. Ashcroft The sulphonylurea receptor confers diazoxide sensitivity on the inwardly rectifying K+ channel Kir6.1 expressed in human embryonic kidney cells J. Physiol. 494 1996 709 714
10. M. Yamada, S. Isomoto, S. Matsumoto, C. Kondo, T. Shindo, and Y. Horio Sulphonylurea receptor 2B and Kir6.1 form a sulphonylurea-sensitive but ATP-insensitive K+ channel J. Physiol. 499 1997 715 720
11. J.P. Clement, K. Kunjilwar, G. Gonzalez, M. Schwanstecher, U. Panten, and L. Aguilar-Bryan Association and stoichiometry of KATP channel subunits Neuron 18 1997 827 838
12. N. Inagaki, T. Gonoi, and S. Seino Subunit stoichiometry of the pancreatic beta-cell ATP-sensitive K+ channel FEBS Lett. 409 1997 232 236
13. S.L. Shyng, and C.G. Nichols Octameric stoichiometry of the KATP channel complex J. Gen. Physiol. 110 1997 655 664
14. N. Zerangue, B. Schwappach, Y.N. Jan, and L.Y. Jan A new ER trafficking signal regulates the subunit stoichiometry of plasma membrane KATP channels Neuron 22 1999 537 548
15. I. Gross, A. Toman, I. Uhde, C. Schwanstecher, and M. Schwanstecher Stoichiometry of potassium channel opener action Mol. Pharmacol. 56 1999 1370 1373
16. J.P. Giblin, Y. Cui, L.H. Clapp, and A. Tinker Assembly limits the pharmacological complexity of ATP-sensitive potassium channels J. Biol. Chem. 277 2002 13717 13723
17. F.M. Gribble, S.J. Tucker, S. Seino, and F.M. Ashcroft Tissue specificity of sulfonylureas: studies on cloned cardiac and β-cell KATP channels Diabetes 47 1998 1412 1418
18. M. Dabrowski, F.M. Ashcroft, R. Ashfield, P. Lebrun, B. Pirotte, and J. Egebjerg The novel diazoxide analog 3-isopropylamino-7-methoxy-4H-1,2,4- benzothiadiazine 1,1-dioxide is a selective Kir6.2/SUR1 channel opener Diabetes 51 2002 1896 1906
19. M. Dabrowski, T. Larsen, F.M. Ashcroft, J.B. Hansen, and P. Wahl Potent and selective activation of the pancreatic beta-cell type KATP channel by two novel diazoxide analogues Diabetologia 46 2003 1375 1382
20. N. Inagaki, T. Gonoi, J.P. Clement, C.Z. Wang, L. Aguilar-Bryan, and J. Bryan A family of sulfonylurea receptors determines the pharmacological properties of ATP-sensitive K+ channels Neuron 16 1996 1011 1017
21. S. Isomoto, C. Kondo, M. Yamada, S. Matsumoto, O. Higashiguchi, and Y. Horio A novel sulfonylurea receptor forms with BIR (Kir6.2) a smooth muscle type ATP-sensitive K+ channel J. Biol. Chem. 271 1996 24321 24324
22. N. D'hahan, C. Moreau, A.L. Prost, H. Jacquet, A.E. Alekseev, and A. Terzic Pharmacological plasticity of cardiac ATP-sensitive potassium channels toward diazoxide revealed by ADP Proc. Natl. Acad. Sci. USA 96 1999 12162 12167
23. S.J. Tucker, F.M. Gribble, C. Zhao, S. Trapp, and F.M. Ashcroft Truncation of Kir6.2 produces ATP-sensitive K+ channels in the absence of the sulphonylurea receptor Nature 387 1997 179 183
24. Z. Fan, and J.C. Makielski Anionic phospholipids activate ATP-sensitive potassium channels J. Biol. Chem. 272 1997 5388 5395
25. T. Baukrowitz, U. Schulte, D. Oliver, S. Herlitze, T. Krauter, and S.J. Tucker PIP2 and PIP as determinants for ATP inhibition of KATP channels Science 282 1998 1141 1144
26. S.L. Shyng, and C.G. Nichols Membrane phospholipid control of nucleotide sensitivity of KATP channels Science 282 1998 1138 1141
27. F.M. Gribble, and F. Reimann Pharmacological modulation of KATP channels Biochem. Soc. Trans. 30 2002 333 339
28. A. Terzic, and M. Vivaudou Molecular Pharmacology of ATP-sensitive K+ channels: how and why? S.L. Archer N.J. Rusch Potassium channels in cardiovascular biology 2001 Kluwer Academic/Plenum Publishers New York 257 277
29. F.M. Ashcroft, and F.M. Gribble New windows on the mechanism of action of KATP channel openers Trends Pharmacol. Sci. 21 2000 439 445
30. A. Fujita, and Y. Kurachi Molecular aspects of ATP-sensitive K+ channels in the cardiovascular system and K+ channel openers Pharmacol. Ther. 85 2000 39 53
31. R. Mannhold KATP channel openers: structure-activity relationships and therapeutic potential Med. Res. Rev. 24 2004 213 266
32. M.J. Coghlan, W.A. Carroll, and M. Gopalakrishnan Recent developments in the biology and medicinal chemistry of potassium channel modulators: update from a decade of progress J. Med. Chem. 44 2001 1627 1653
33. U. Quast Potassium channel openers--pharmacological and clinical aspects Fundam. Clin. Pharmacol. 6 1992 279 293
34. G. Edwards, and A.H. Weston Structure-activity relationships of K+ channel openers Trends Pharmacol. Sci. 11 1990 417 442
35. D.W. Robertson, and M.I. Steinberg Potassium channel modulators: scientific applications and therapeutic promise J. Med. Chem. 33 1990 1529 1541
36. A. Loubatìres The use of certain sulfonamides in the treatment of experimental diabetes mellitus Ann. N. Y. Acad. Sci. 67 1956 187 206
37. A. Loubatìres, M.M. Mariani, R. Alric, J. Capal, G. Ribes, and H. de Malbosc A new particularly active hypoglycemic sulfonamide, HB 419 (glibenclamide) Diabetes 1 Suppl 1968 79 86
38. R. Paulissian Diazoxide Int. Anesthesiol. Clin. 16 1978 201 237
39. J.D. Thompson, D. Higgins, T.J. Gandgibson, and W. Clustal improving the sensitivity of progressive multiple sequence alignment through sequence weighting, positions-specific gap penalties and weight matrix choice Nucleic Acids Res. 22 1994 4673 4680
40. G. Chang, and C.B. Roth Structure of MsbA from E. coli: a homolog of the multidrug resistance ATP binding cassette (ABC) transporters Science 293 2001 1793 1800
41. K.P. Löcher, A.T. Lee, and D.C. Rees The E. coli BtuCD structure: a framework for ABC transporter architecture and mechanism Science 296 2002 1091 1098
42. G. Chang Structure of MsbA from Vibrio cholera: a multidrug resistance ABC transporter homolog in a closed conformation J. Mol. Biol. 330 2003 419 430
43. M. Dean, A. Rzhetsky, and R. Allikmets The human ATP-binding cassette (ABC) transporter superfamily Genome Res. 11 2001 1156 1166
44. G.D. Kruh, H. Zeng, P.A. Rea, G. Liu, Z.S. Chen, and K. Lee MRP subfamily transporters and resistance to anticancer agents J. Bioenerg. Biomembr. 33 2001 493 501
45. E.M. Leslie, R.G. Deeley, and S.P. Cole Toxicological relevance of the multidrug resistance protein 1, MRP1 (ABCC1) and related transporters Toxicology 167 2001 3 23
46. D.C. Gadsby, and A.C. Nairn Control of CFTR channel gating by phosphorylation and nucleotide hydrolysis Physiol. Rev. 79 1999 S77 107
47. R. Tommasini, R. Evers, E. Vogt, C. Mornet, G.J. Zaman, and A.H. Schinkel The human multidrug resistance-associated protein functionally complements the yeast cadmium resistance factor 1 Proc. Natl. Acad. Sci. USA 93 1996 6743 6748
48. E.K. Lee, M. Kwon, J.H. Ko, H.C. Yi, M.G. Hwang, and S.C. Chang Binding of sulfonylurea by AtMRP5, an Arabidopsis multidrug resistance-related protein that functions in salt tolerance Plant Physiol. 134 2004 528 538
49. K. Kunzelmann CFTR: interacting with everything? News Physiol. Sci. 16 2001 167 170
50. A. Ishida-Takahashi, H. Otani, C. Takahashi, T. Washizuka, K. Tsuji, and M. Noda Cystic fibrosis transmembrane conductance regulator mediates sulphonylurea block of the inwardly rectifying K+ channel Kir6.1 J. Physiol. 508 1998 23 30
51. D.N. Sheppard, and M.J. Welsh Effect of ATP-sensitive K+ channel regulators on cystic fibrosis transmembrane conductance regulator chloride currents J. Gen. Physiol. 100 1992 573 591
52. D.N. Sheppard, and K.A. Robinson Mechanism of glibenclamide inhibition of cystic fibrosis transmembrane conductance regulator Cl- channels expressed in a murine cell line J. Physiol. 503 1997 333 346
53. B.J. Zünkler, G. Trube, and U. Panten How do sulfonylureas approach their receptor in the B-cell membrane? Naunyn Schmiedebergs Arch. Pharmacol. 340 1989 328 332
54. I. Findlay Effects of pH upon the inhibition by sulphonylurea drugs of ATP-sensitive K+ channels in cardiac muscle J. Pharmacol. Exp. Ther. 262 1992 71 79
55. L. Payen, L. Delugin, A. Courtois, Y. Trinquart, A. Guillouzo, and O. Fardel The sulphonylurea glibenclamide inhibits multidrug resistance protein (MRP1) activity in human lung cancer cells Br. J. Pharmacol. 132 2001 778 784
56. P.E. Golstein, A. Boom, J. Van Geffel, P. Jacobs, B. Masereel, and R. Beauwens P-glycoprotein inhibition by glibenclamide and related compounds Pflug Arch. Eur. J. Physiol. 437 1999 652 660
57. T. Ninomiya, M. Takano, T. Haruna, Y. Kono, and M. Horie Verapamil, a Ca2+ entry blocker, targets the pore-forming subunit of cardiac type KATP channel (Kir6.2) J. Cardiovasc. Pharmacol. 42 2003 161 168
58. T. Yanagisawa, K. Satoh, and N. Taira Circumstantial evidence for increased potassium conductance of membrane of cardiac muscle by 2-nicotinamidoethyl nitrate (SG-75) Jpn. J. Pharmacol. 29 1979 687 694
59. J.C. Henquin, and H.P. Meissner Opposite effects of tolbutamide and diazoxide on 86Rb+ fluxes and membrane potential in pancreatic B cells Biochem. Pharmacol. 31 1982 1407 1415
60. S.W. Weir, and A.H. Weston The effects of BRL 34915 and nicorandil on electrical and mechanical activity and on 86Rb efflux in rat blood vessels Br. J. Pharmacol. 88 1986 121 128
61. O.P. Hamill, A. Marty, E. Neher, B. Sakmann, and F.J. Sigworth Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches Pflug Arch. Eur. J. Physiol. 391 1981 85 100
62. A. Noma ATP-regulated K+ channels in cardiac muscle Nature 305 1983 147 148
63. G. Trube, P. Rorsman, and T. Ohno-Shosaku Opposite effects of tolbutamide and diazoxide on the ATP-dependent K+ channel in mouse pancreatic beta-cells Pflug Arch. Eur. J. Physiol. 407 1986 493 499
64. D. Escande, D. Thuringer, S. Leguern, and I. Cavero The potassium channel opener cromakalim (BRL 34915) activates ATP-dependent K+ channels in isolated cardiac myocytes Biochem. Biophys. Res. Commun. 154 1988 620 625
65. J.P. Arena, and R.S. Kass Activation of ATP-sensitive K channels in heart cells by pinacidil: dependence on ATP Am. J. Physiol. 257 1989 H2092 H2096
66. P.W. Manley, C. Löffler-Walz, U. Russ, A. Hambrock, T. Moenius, and U. Quast Synthesis and characterization of a novel tritiated KATP channel opener with a benzopyran structure Br. J. Pharmacol. 133 2001 275 285
67. R. Davis-Taber, E.J. Molinari, R.J. Altenbach, K.L. Whiteaker, C.C. Shieh, and G. Rotert 125I A-312110, a novel high-affinity 1,4-dihydropyridine ATP-sensitive K+ channel opener: characterization and pharmacology of binding Mol. Pharmacol. 64 2003 143 153
68. H. Felsch, U. Lange, A. Hambrock, C. Löffler-Walz, U. Russ, and W.A. Carroll Interaction of a novel dihydropyridine K+ channel opener, A-312110, with recombinant sulphonylurea receptors and KATP channels: comparison with the cyanoguanidine P1075 Br. J. Pharmacol. 141 2004 1098 1105
69. K.M. Bray, and U. Quast A specific binding site for K+ channel openers in rat aorta J. Biol. Chem. 267 1992 11689 11692
70. U. Quast, K.M. Bray, H. Andres, P.W. Manley, Y. Baumlin, and J. Dosogne Binding of the K+ channel opener [3H]P1075 in rat isolated aorta--relationship to functional effects of openers and blockers Mol. Pharmacol. 43 1993 474 481
71. F.J. Hoffman, J.B. Lenfers, E. Niemers, U. Pleiss, A. Scriabine, and R.A. Janis High affinity binding of a potassium channel agonist to intact rat insulinoma cells Biochem. Biophys. Res. Commun. 190 1993 551 558
72. K.E.J. Dickinson, C.C. Bryson, R.B. Cohen, L. Rogers, D.W. Green, and K.S. Atwal Nucleotide regulation and characteristics of potassium channel opener binding to skeletal muscle membranes Mol. Pharmacol. 52 1997 473 481
73. K.S. Atwal, G.J. Grover, N.J. Lodge, D.E. Normandin, S.C. Traeger, and P.G. Sleph Binding of ATP-sensitive potassium channel (KATP) openers to cardiac membranes: correlation of binding affinities with cardioprotective and smooth muscle relaxing potencies J. Med. Chem. 41 1998 271 275
74. C. Löffler-Walz, and U. Quast Binding of KATP channel modulators in rat cardiac membranes Br. J. Pharmacol. 123 1998 1395 1402
75. A. Hambrock, C. Löffler-Walz, Y. Kurachi, and U. Quast Mg2+ and ATP dependence of KATP channel modulator binding to the recombinant sulphonylurea receptor, SUR2B Br. J. Pharmacol. 125 1998 577 583
76. A. Hambrock, C. Löffler-Walz, D. Kloor, U. Delabar, Y. Horio, and Y. Kurachi K+ channel modulator binding to sulfonylurea receptors SUR2A and SUR2B: opposite effects of MgADP Mol. Pharmacol. 55 1999 832 840
77. M. Schwanstecher, C. Sieverding, H. Dorschner, I. Gross, L. Aguilar-Bryan, and C. Schwanstecher Potassium channel openers require ATP to bind to and act through sulfonylurea receptors EMBO J. 17 1998 5529 5535
78. U. Russ, U. Lange, C. Löffler-Walz, A. Hambrock, and U. Quast Binding and effect of KATP channel openers in the absence of Mg2+ Br. J. Pharmacol. 139 2003 368 380
79. F.M. Gribble, F. Reimann, R. Ashfield, and F.M. Ashcroft Nucleotide modulation of pinacidil stimulation of the cloned KATP channel Kir6.2/SUR2A Mol. Pharmacol. 57 2000 1256 1261
80. F. Reimann, F.M. Gribble, and F.M. Ashcroft Differential response of KATP channels containing SUR2A or SUR2B subunits to nucleotides and pinacidil Mol. Pharmacol. 58 2000 1318 1355
81. U. Russ, A. Hambrock, F. Artunc, C. Löffler-Walz, Y. Horio, and Y. Kurachi Coexpression with the inward rectifier K+ channel Kir6.1 increases the affinity of the vascular sulfonylurea receptor SUR2B for glibenclamide Mol. Pharmacol. 56 1999 955 961
82. R. Ashfield, F.M. Gribble, S.J.H. Ashcroft, and F.M. Ashcroft Identification of the high-affinity tolbutamide site on the SUR1 subunit of the KATP channel Diabetes 48 1999 1341 1347
83. A. Hambrock, C. Löffler-Walz, U. Russ, U. Lange, and U. Quast Characterization of a mutant sulfonylurea receptor SUR2B with high affinity for sulfonylureas and openers: differences in the coupling to Kir6.x subtypes Mol. Pharmacol. 60 2001 190 199
84. K. Imoto, C. Methfessel, B. Sakmann, M. Mishina, Y. Mori, and T. Konno Location of a delta-subunit region determining ion transport through the acetylcholine receptor channel Nature 324 1986 670 674
85. T. Tanabe, K.G. Beam, B.A. Adams, T. Niidome, and S. Numa Regions of the skeletal muscle dihydropyridine receptor critical for excitation-contraction coupling Nature 346 1990 567 569
86. T. Tanabe, B.A. Adams, S. Numa, and K.G. Beam Repeat I of the dihydropyridine receptor is critical in determining calcium channel activation kinetics Nature 352 1991 800 803
87. T. Shindo, M. Yamada, S. Isomoto, Y. Horio, and Y. Kurachi SUR2 subtype (A and B)-dependent differential activation of the cloned ATP-sensitive K+ channels by pinacidil and nicorandil Br. J. Pharmacol. 124 1998 985 991
88. M. Bienengraeber, A.E. Alekseev, M.R. Abraham, A.J. Carrasco, C. Moreau, and M. Vivaudou ATPase activity of the sulfonylurea receptor: a catalytic function for the KATP channel complex FASEB J. 14 2000 1943 1952
89. L.V. Zingman, A.E. Alekseev, M. Bienengraeber, D. Hodgson, A.B. Karger, and P.P. Dzeja Signaling in channel/enzyme multimers: ATPase transitions in SUR module gate ATP-sensitive K+ conductance Neuron 31 2001 233 245
90. D'hahan N. Jacquet H Moreau C, Catty P, Vivaudou M. A transmembrane domain of the sulfonylurea receptor mediates activation of ATP-sensitive K+ channels by K+ channel openers Mol. Pharmacol. 56 1999 308 315
91. I. Uhde, A. Toman, I. Gross, C. Schwanstecher, and M. Schwanstecher Identification of the potassium channel opener site on sulfonylurea receptors J. Biol. Chem. 274 1999 28079 28082
92. A.P. Babenko, G. Gonzalez, and J. Bryan Pharmaco-topology of sulfonylurea receptors--separate domains of the regulatory subunits of KATP channel isoforms are required for selective interaction with K+ channel openers J. Biol. Chem. 275 2000 717 720
93. C. Moreau, H. Jacquet, A.L. Prost, N. D'Hahan, and M. Vivaudou The molecular basis of the specificity of action of KATP channel openers EMBO J. 19 2000 6644 6651
94. K.I. Ito, S.L. Olsen, W. Qiu, R.G. Deeley, and S.P.C. Cole Mutation of a single conserved tryptophan in multidrug resistance protein 1 (MRP1/ABCC1) results in loss of drug resistance and selective loss of organic anion transport J. Biol. Chem. 276 2001 15616 15624
95. D.W. Zhang, S.P.C. Cole, and R.G. Deeley Identification of a nonconserved amino acid residue in multidrug resistance protein 1 important for determining substrate specificity--evidence for functional interaction between transmembrane helices 14 and 17 J. Biol. Chem. 276 2001 34966 34974
96. T.W. Loo, and D.M. Clarke Location of the rhodamine-binding site in the human multidrug resistance P-glycoprotein J. Biol. Chem. 277 2002 44332 44338
97. E.A. Cartier, S. Shen, and S.L. Shyng Modulation of the trafficking efficiency and functional properties of ATP-sensitive potassium channels through a single amino acid in the sulfonylurea receptor J. Biol. Chem. 278 2003 7081 7090
98. M.G. Garrino, T.D. Plant, and J.C. Henquin Effects of putative activators of K+ channels in mouse pancreatic β-cells Br. J. Pharmacol. 98 1989 957 965
99. M.J. Dunne, R.J. Aspinall, and O.H. Petersen The effects of cromakalim on ATP-sensitive potassium channels in insulin-secreting cells Br. J. Pharmacol. 99 1990 169 175
100. M.J. Dunne Effects of pinacidil, RP 49356 and nicorandil on ATP-sensitive potassium channels in insulin-secreting cells Br. J. Pharmacol. 99 1990 487 492
101. J.H. Jaggar, E.A. Harding, B.J. Ayton, and M.J. Dunne Interaction of diazoxide and cromakalim with ATP-regulated K+ channels in rodent and clonal insulin-secreting cells J. Mol. Endocrinol. 10 1993 59 70
102. M. Schwanstecher, C. Brandt, S. Behrends, U. Schaupp, and U. Panten Effect of MgATP on pinacidil-induced displacement of glibenclamide from the sulphonylurea receptor in a pancreatic beta-cell line and rat cerebral cortex Br. J. Pharmacol. 106 1992 295 301
103. K.D. Garlid, P. Paucek, V. Yarov-Yarovoy, H.N. Murray, R.B. Darbenzio, and A.J. D'Alonzo Cardioprotective effect of diazoxide and its interaction with mitochondrial ATP-Sensitive K+ channels--possible mechanism of cardioprotection Circ. Res. 81 1997 1072 1082
104. B. O'Rourke Myocardial KATP channels in preconditioning Circ. Res. 87 2000 845 855
105. M. Suzuki, T. Saito, T. Sato, M. Tamagawa, T. Miki, and S. Seino Cardioprotective effect of diazoxide is mediated by activation of sarcolemmal but not mitochondrial ATP-sensitive potassium channels in mice Circulation 107 2003 682 685
106. T. Matsuoka, K. Matsushita, Y. Katayama, A. Fujita, K. Inageda, and M. Tanemoto C-terminal tails of sulfonylurea receptors control ADP-induced activation and diazoxide modulation of ATP-sensitive K+ channels Circ. Res. 87 2000 873 880
107. K. Matsushita, K. Kinoshita, T. Matsuoka, A. Fujita, T. Fujikado, and Y. Tano Intramolecular interaction of SUR2 subtypes for intracellular ADP-induced differential control of KATP channels Circ. Res. 90 2002 554 561
108. I. Findlay, and J.F. Faivre ATP-sensitive K channels in heart muscle. Spare channels FEBS Lett. 279 1991 95 97
109. B. Pelzmann, P. Schaffer, E. Bernhart, P. Lang, H. Machler, and B. Rigler Effects of K+ channel openers on I-KATP of human atrial myocytes at physiological temperatures Naunyn Schmiedebergs Arch. Pharmacol. 363 2001 125 132
110. M.C. Sanguinetti, A.L. Scott, G.J. Zingaro, and P.K. Siegl BRL 34915 (cromakalim) activates ATP-sensitive K+ current in cardiac muscle Proc. Natl. Acad. Sci. USA 85 1988 8360 8364
111. T. Krauter, J.P. Ruppersberg, and T. Baukrowitz Phospholipids as modulators of KATP channels: distinct mechanisms for control of sensitivity to sulphonylureas, K+ channel openers, and ATP Mol. Pharmacol. 59 2001 1086 1093
112. D. Enkvetchakul, G. Loussouarn, E. Makhina, S.L. Shyng, and C.G. Nichols The kinetic and physical basis of KATP channel gating: toward a unified molecular understanding Biophys. J. 78 2000 2334 2348
113. A.L. Kuo, J.M. Gulbis, J.F. Antcliff, T. Rahman, E.D. Lowe, and J. Zimmer Crystal structure of the potassium channel KirBac1.1 in the closed state Science 300 2003 1922 1926
114. K.W. Chan, H. Zhang, and D.E. Logothetis N-terminal transmembrane domain of the SUR controls trafficking and gating of Kir6 channel subunits EMBO J. 22 2003 3833 3843
115. A.P. Babenko, and J. Bryan SUR domains that associate with and gate KATP pores define a novel gatekeeper J. Biol. Chem. 278 2003 41577 41580
116. R.D. Rainbow, M. James, D. Hudman, M. Al-Johi, H. Singh, and P.J. Watson C-terminal domain of sulphonylurea receptor 2A interacts with pore-forming Kir6 subunits in KATP channels Biochem. J. 379 2004 173 181
117. J.D. Campbell, M.S.P. Sansom, and F.M. Ashcroft Potassium channel regulation--structural insights into the function of the nucleotide-binding domains of the human sulphonylurea receptor EMBO Rep. 4 2003 1038 1042
118. P.M. Jones, and A.M. George The ABC transporter structure and mechanism: perspectives on recent research Cell. Mol. Life Sci. 61 2004 682 699
119. D. Thuringer, and D. Escande Apparent competition between ATP and the potassium channel opener RP 49356 on ATP-sensitive K+ channels of cardiac myocytes Mol. Pharmacol. 36 1989 897 902
120. C. Forestier, J. Pierrard, and M. Vivaudou Mechanism of action of K channel openers on skeletal muscle KATP channels--interactions with nucleotides and protons J. Gen. Physiol. 107 1996 489 502