메뉴 건너뛰기




Volumn 11, Issue 21, 2005, Pages 2717-2736

Physiology and pharmacology of two-pore domain potassium channels

Author keywords

Anesthetic agent; Background potassium channel; Free fatty acids; G protein coupled receptor; Mechanosensitivity; pH; Two pore domain potassium channel

Indexed keywords

BUPIVACAINE; CLOFILIUM; DESFLURANE; G PROTEIN COUPLED RECEPTOR; GLIBENCLAMIDE; GUANINE NUCLEOTIDE BINDING PROTEIN; HALOTHANE; INWARDLY RECTIFYING POTASSIUM CHANNEL; ISOFLURANE; LIDOCAINE; MESSENGER RNA; NEUROTRANSMITTER; POTASSIUM ION; PROPAFENONE; PROTEIN 14 3 3; QUINIDINE; SMALL INTERFERING RNA; TANDEM PORE DOMAIN POTASSIUM CHANNEL;

EID: 22944473967     PISSN: 13816128     EISSN: None     Source Type: Journal    
DOI: 10.2174/1381612054546824     Document Type: Review
Times cited : (131)

References (163)
  • 1
    • 0030451916 scopus 로고    scopus 로고
    • Cloning, functional expression and brain localization of a novel unconventional outward rectifier K+ channel
    • Fink M, Duprat F, Lesage F, Reyes R, Romey G, Heurteaux C, et al. Cloning, functional expression and brain localization of a novel unconventional outward rectifier K+ channel. EMBO J 1996; 15: 6854-62.
    • (1996) EMBO J. , vol.15 , pp. 6854-6862
    • Fink, M.1    Duprat, F.2    Lesage, F.3    Reyes, R.4    Romey, G.5    Heurteaux, C.6
  • 3
    • 0038015527 scopus 로고    scopus 로고
    • Cellular localization of TWIK-1, a two-pore-domain potassium channel in the rodent inner car
    • Nicolas MT, Barhanin J, Reyes R, Dememes D. Cellular localization of TWIK-1, a two-pore-domain potassium channel in the rodent inner car. Hear Res 2003; 181: 20-6.
    • (2003) Hear Res. , vol.181 , pp. 20-26
    • Nicolas, M.T.1    Barhanin, J.2    Reyes, R.3    Dememes, D.4
  • 4
    • 0035977711 scopus 로고    scopus 로고
    • Distribution analysis of human two pore domain potassium channels in tissues of the central nervous system and periphery
    • Medhurst AD, Rennie G, Chapman CG, Meadows H, Duckworth MD, Kelsell RE, et al. Distribution analysis of human two pore domain potassium channels in tissues of the central nervous system and periphery. Brain Res Mol Brain Res 2000; 86: 101-14.
    • (2000) Brain Res. Mol. Brain Res. , vol.86 , pp. 101-114
    • Medhurst, A.D.1    Rennie, G.2    Chapman, C.G.3    Meadows, H.4    Duckworth, M.D.5    Kelsell, R.E.6
  • 5
    • 0030821520 scopus 로고    scopus 로고
    • TASK, a human background K+ channel to sense external pH variations near physiological pH
    • Duprat F, Lesage F, Fink M, Reyes R. Heurteaux C, Lazdunski M. TASK, a human background K+ channel to sense external pH variations near physiological pH. EMBO J 1997; 16: 5464-71.
    • (1997) EMBO J. , vol.16 , pp. 5464-5471
    • Duprat, F.1    Lesage, F.2    Fink, M.3    Reyes, R.4    Heurteaux, C.5    Lazdunski, M.6
  • 6
    • 0034737472 scopus 로고    scopus 로고
    • TASK-3, a new member of the tandem pore K(+) channel family
    • Kim Y, Bang H, Kim D. TASK-3, a new member of the tandem pore K(+) channel family. J Biol Chem 2000; 275: 9340-7.
    • (2000) J. Biol. Chem. , vol.275 , pp. 9340-9347
    • Kim, Y.1    Bang, H.2    Kim, D.3
  • 7
    • 0034595787 scopus 로고    scopus 로고
    • TASK-3, a novel tandem pore domain acid-sensitive K+ channel. An extracellular histiding as pH sensor
    • Rajan S, Wischmeyer E, Xin Liu G, Preisig-Muller R, Daut J, Karschin A, et al. TASK-3, a novel tandem pore domain acid-sensitive K+ channel. An extracellular histiding as pH sensor. J Biol Chem 2000; 275: 16650-7.
    • (2000) J. Biol. Chem. , vol.275 , pp. 16650-16657
    • Rajan, S.1    Wischmeyer, E.2    Xin Liu, G.3    Preisig-Muller, R.4    Daut, J.5    Karschin, A.6
  • 8
    • 0032735159 scopus 로고    scopus 로고
    • TBAK-1 and TASK-1, two-pore K(+) channel subunits: Kinetic properties and expression in rat heart
    • Kim Y, Bang H, Kim D. TBAK-1 and TASK-1, two-pore K(+) channel subunits: kinetic properties and expression in rat heart. Am J Physiol 1999; 277: H1669-78.
    • (1999) Am. J. Physiol. , vol.277
    • Kim, Y.1    Bang, H.2    Kim, D.3
  • 9
    • 0035478067 scopus 로고    scopus 로고
    • Cns distribution of members of the two-pore-domain (KCNK) potassium channel family
    • Talley EM, Solorzano G, Lei Q, Kim D, Bayiiss DA. Cns distribution of members of the two-pore-domain (KCNK) potassium channel family. J Neurosci 2001; 21: 7491-505.
    • (2001) J. Neurosci. , vol.21 , pp. 7491-7505
    • Talley, E.M.1    Solorzano, G.2    Lei, Q.3    Kim, D.4    Bayiiss, D.A.5
  • 10
    • 0035687301 scopus 로고    scopus 로고
    • Expression pattern in brain of TASK-1, TASK-3, and a tandem pore domain K(+) channel subunit, TASK-5, associated with the central auditory nervous systems
    • Karschin C, Wischmeyer E, Preisig-Muller R, Rajan S, Derst C, Grzeschik KH, et al. Expression pattern in brain of TASK-1, TASK-3, and a tandem pore domain K(+) channel subunit, TASK-5, associated with the central auditory nervous systems. Mol Cell Neurosci 2001; 18: 632-78.
    • (2001) Mol. Cell Neurosci. , vol.18 , pp. 632-678
    • Karschin, C.1    Wischmeyer, E.2    Preisig-Muller, R.3    Rajan, S.4    Derst, C.5    Grzeschik, K.H.6
  • 12
    • 0035096618 scopus 로고    scopus 로고
    • Functional characterisation of human TASK-3, and acid-sensitive two-pore domain potassium channel
    • Meadows HJ, Randall AD. Functional characterisation of human TASK-3, and acid-sensitive two-pore domain potassium channel. Neuropharmacology 2001; 40: 551-9.
    • (2001) Neuropharmacology , vol.40 , pp. 551-559
    • Meadows, H.J.1    Randall, A.D.2
  • 13
    • 0035816558 scopus 로고    scopus 로고
    • Block of Kcnk3 by protons. Evidence that 2-P-domain potassium channel subunits function as homodimers
    • Lopes CM, Zilberberg N, Goldstein SA. Block of Kcnk3 by protons. Evidence that 2-P-domain potassium channel subunits function as homodimers. J Biol Chem 2001; 276: 24449-52.
    • (2001) J. Biol. Chem. , vol.276 , pp. 24449-24452
    • Lopes, C.M.1    Zilberberg, N.2    Goldstein, S.A.3
  • 14
    • 0037291979 scopus 로고    scopus 로고
    • Determinants of pH sensing in the two-pore domain K(+) channel TASK-1 and -2
    • Morton MJ, O'Connell AD, Sivaprasadarao A, Hunter M. Determinants of pH sensing in the two-pore domain K(+) channel TASK-1 and -2. Pflugers Arch 2003; 445: 577-83.
    • (2003) Pflugers Arch. , vol.445 , pp. 577-583
    • Morton, M.J.1    O'Connell, A.D.2    Sivaprasadarao, A.3    Hunter, M.4
  • 15
    • 2442637567 scopus 로고    scopus 로고
    • The selectivity filter of the tandem pore potassium channel TASK-1 and its pH-sensitivity and ionic selectivity
    • Yuill K, Ashmole I, Stanfield PR. The selectivity filter of the tandem pore potassium channel TASK-1 and its pH-sensitivity and ionic selectivity. Pflugers Arch 2003; 4448: 63-69.
    • (2003) Pflugers Arch. , vol.4448 , pp. 63-69
    • Yuill, K.1    Ashmole, I.2    Stanfield, P.R.3
  • 16
    • 0035185293 scopus 로고    scopus 로고
    • TASK-1 is a highly modulated pH-sensitive 'leak' K(+) channel expressed in brainstem respiratory neurons
    • Bayliss DA, Talley EM, Sirois JE, Lei Q. TASK-1 is a highly modulated pH-sensitive 'leak' K(+) channel expressed in brainstem respiratory neurons. Respir Physiol 2001; 129: 159-74.
    • (2001) Respir. Physiol. , vol.129 , pp. 159-174
    • Bayliss, D.A.1    Talley, E.M.2    Sirois, J.E.3    Lei, Q.4
  • 17
    • 0347479235 scopus 로고    scopus 로고
    • Synaptic cleft acidification and modulation of short-term depression by exocytosed protons in retinal bipolar cells
    • Palmer MJ, Hull C, Vigh J, Von Gersdorff H. Synaptic cleft acidification and modulation of short-term depression by exocytosed protons in retinal bipolar cells. J Neurosci 2003; 23: 11332-41.
    • (2003) J. Neurosci. , vol.23 , pp. 11332-11341
    • Palmer, M.J.1    Hull, C.2    Vigh, J.3    Von Gersdorff, H.4
  • 18
    • 0037101548 scopus 로고    scopus 로고
    • Characterization of four types of background potassium channels in rat cerebellar granule neurons
    • Han J, Truell J, Gnatenco C, Kim D. Characterization of four types of background potassium channels in rat cerebellar granule neurons. J Physiol 2002; 542: 431-44.
    • (2002) J. Physiol. , vol.542 , pp. 431-444
    • Han, J.1    Truell, J.2    Gnatenco, C.3    Kim, D.4
  • 19
    • 0031915250 scopus 로고    scopus 로고
    • An open rectifier potassium channel with two pore domains in tandem cloned from rat cerebellum
    • Leonoudakis D, Gray AT, Winegar BD, Kindler CH, Harada M, Taylor DM, et al. An open rectifier potassium channel with two pore domains in tandem cloned from rat cerebellum. J Neurosci 1998; 18: 868-77
    • (1998) J. Neurosci. , vol.18 , pp. 868-877
    • Leonoudakis, D.1    Gray, A.T.2    Winegar, B.D.3    Kindler, C.H.4    Harada, M.5    Taylor, D.M.6
  • 20
    • 0037401021 scopus 로고    scopus 로고
    • Drug- and mutagenesis-induced changes in the selectivity filter of a cardiac two-pore background K+ channel
    • Hajdu P, Ulens C, Panyi G, Tytgat J. Drug- and mutagenesis-induced changes in the selectivity filter of a cardiac two-pore background K+ channel. Cardiovasc Res 2003; 58: 46-54.
    • (2003) Cardiovasc. Res. , vol.58 , pp. 46-54
    • Hajdu, P.1    Ulens, C.2    Panyi, G.3    Tytgat, J.4
  • 21
    • 0037333470 scopus 로고    scopus 로고
    • Ruthenium red inhibits TASK-3 potassium channel by interconnecting glutamate 70 of the two subunits
    • Czirjak G, Enyedi P. Ruthenium red inhibits TASK-3 potassium channel by interconnecting glutamate 70 of the two subunits. Mol Pharmacol 2003; 63: 646-52.
    • (2003) Mol. Pharmacol. , vol.63 , pp. 646-652
    • Czirjak, G.1    Enyedi, P.2
  • 23
    • 0034281367 scopus 로고    scopus 로고
    • The TASK-1 two-pore domain K+ channel is a molecular substrate for neuronal effects of inhalation anesthetics
    • Sirois JE, Lei Q, Talley EM, Lynch C, 3rd. Bayliss DA. The TASK-1 two-pore domain K+ channel is a molecular substrate for neuronal effects of inhalation anesthetics. J Neurosci 2000; 20: 6347-54.
    • (2000) J. Neurosci. , vol.20 , pp. 6347-6354
    • Sirois, J.E.1    Lei, Q.2    Talley, E.M.3    Lynch III, C.4    Bayliss, D.A.5
  • 24
    • 0037124105 scopus 로고    scopus 로고
    • Modulation of TASK-1 (Kcnk3) and TASK-3 (Kcnk9) potassium channels: Volatile anesthetics and neurotransmitters share a molecular site of action
    • Talley EM, Bayliss DA. Modulation of TASK-1 (Kcnk3) and TASK-3 (Kcnk9) potassium channels: volatile anesthetics and neurotransmitters share a molecular site of action. J Biol Chem 2002; 277: 17733-42.
    • (2002) J. Biol. Chem. , vol.277 , pp. 17733-17742
    • Talley, E.M.1    Bayliss, D.A.2
  • 25
    • 0035863195 scopus 로고    scopus 로고
    • The endocannabinoid anandamide is a direct and selective blocker of the background K(+) channel TASK-1
    • Maingret F, Patel AJ, Lazdunski M, Honore E. The endocannabinoid anandamide is a direct and selective blocker of the background K(+) channel TASK-1. EMBO J 2001; 20: 47-54.
    • (2001) EMBO J. , vol.20 , pp. 47-54
    • Maingret, F.1    Patel, A.J.2    Lazdunski, M.3    Honore, E.4
  • 27
    • 0037085478 scopus 로고    scopus 로고
    • Formation of functional heterodimers between the TASK-1 and TASK-3 two-pore domain potassium channel subunits
    • Czirjak G, Enyedi P. Formation of functional heterodimers between the TASK-1 and TASK-3 two-pore domain potassium channel subunits. J Biol Chem 2002; 277: 5426-32.
    • (2002) J. Biol. Chem. , vol.277 , pp. 5426-5432
    • Czirjak, G.1    Enyedi, P.2
  • 28
    • 0036188942 scopus 로고    scopus 로고
    • TASK-3 dominates the background potassium conductance in rat adrenal glomerulosa cells
    • Czirjak G, Enyedi P. TASK-3 dominates the background potassium conductance in rat adrenal glomerulosa cells. Mol Endocrinol 2002; 16: 621-9.
    • (2002) Mol. Endocrinol. , vol.16 , pp. 621-629
    • Czirjak, G.1    Enyedi, P.2
  • 29
    • 0344616894 scopus 로고    scopus 로고
    • GABA mediates autoreceptor feedback inhibition in the rat carotid body via presynaptic GABAB receptors and TASK-1
    • Fearon IM, Zhang M, Vollmer C, Nurse CA. GABA mediates autoreceptor feedback inhibition in the rat carotid body via presynaptic GABAB receptors and TASK-1. J Physiol 2003; 553: 83-94.
    • (2003) J. Physiol. , vol.553 , pp. 83-94
    • Fearon, I.M.1    Zhang, M.2    Vollmer, C.3    Nurse, C.A.4
  • 30
    • 0038069071 scopus 로고    scopus 로고
    • 5-HT1A receptors increase excitability of spinal motoneurons by inhibiting a TASK-1-like K+ current in the adult turtle
    • Perrier JF, Alaburda A, Hounsgaard J. 5-HT1A receptors increase excitability of spinal motoneurons by inhibiting a TASK-1-like K+ current in the adult turtle. J Physiol 2003; 548: 485-92.
    • (2003) J. Physiol. , vol.548 , pp. 485-492
    • Perrier, J.F.1    Alaburda, A.2    Hounsgaard, J.3
  • 32
    • 0142041897 scopus 로고    scopus 로고
    • Mechanisms underlying excitatory effects of group I metabotropic glutamate receptors via inhibition of 2P domain K+ channels
    • Chemin J, Girard C, Duprat F, Lesage F, Romey G, Lazdunski M. Mechanisms underlying excitatory effects of group I metabotropic glutamate receptors via inhibition of 2P domain K+ channels. EMBO J 2003; 22: 5403-11.
    • (2003) EMBO J. , vol.22 , pp. 5403-5411
    • Chemin, J.1    Girard, C.2    Duprat, F.3    Lesage, F.4    Romey, G.5    Lazdunski, M.6
  • 33
    • 0034536909 scopus 로고    scopus 로고
    • The role of Ca2+-stores in the muscarinic inhibition of the K+ current IK(SO) in neonatal rat cerebellar granule cells
    • Boyd DF, Millar JA, Watkins CS, Mathie A. The role of Ca2+-stores in the muscarinic inhibition of the K+ current IK(SO) in neonatal rat cerebellar granule cells. J Physiol 2000; 529 Pt 2: 321-31.
    • (2000) J. Physiol. , vol.529 , Issue.PART 2 , pp. 321-331
    • Boyd, D.F.1    Millar, J.A.2    Watkins, C.S.3    Mathie, A.4
  • 34
    • 0032546013 scopus 로고    scopus 로고
    • Direct activation of inward rectifier potassium channels by PIP2 and its stabilization by Gbetagamma
    • Huang CL, Feng S, Hilgemann DW. Direct activation of inward rectifier potassium channels by PIP2 and its stabilization by Gbetagamma. Nature 1998; 391: 803-6.
    • (1998) Nature , vol.391 , pp. 803-806
    • Huang, C.L.1    Feng, S.2    Hilgemann, D.W.3
  • 35
    • 0037098726 scopus 로고    scopus 로고
    • Convergent and reciprocal modulation of a leak K+ current and I(h) by an inhalational anaesthetic and neurotransmitters in rat brainstem motoneurones
    • Sirois JE, Lynch C, 3rd, Bayliss DA. Convergent and reciprocal modulation of a leak K+ current and I(h) by an inhalational anaesthetic and neurotransmitters in rat brainstem motoneurones. J Physiol 2002; 541: 717-29.
    • (2002) J. Physiol. , vol.541 , pp. 717-729
    • Sirois, J.E.1    Lynch III, C.2    Bayliss, D.A.3
  • 36
    • 0032614021 scopus 로고    scopus 로고
    • Potential identification of the O2-sensitive K+ current in a human neuroepithelial body-derived cell linc
    • O'Kelly I, Stephens RH, Peers C, Kemp PJ. Potential identification of the O2-sensitive K+ current in a human neuroepithelial body-derived cell linc. Am J Physiol 1999; 276: L96-L104.
    • (1999) Am. J. Physiol. , vol.276
    • O'Kelly, I.1    Stephens, R.H.2    Peers, C.3    Kemp, P.J.4
  • 37
    • 0034658566 scopus 로고    scopus 로고
    • An oxygen-, acid- and anaesthetic-sensitive TASK-like background potassium channel in rat arterial chemoreceptor cells
    • Buckler KJ, Williams BA, Honore E. An oxygen-, acid- and anaesthetic-sensitive TASK-like background potassium channel in rat arterial chemoreceptor cells. J Physiol 2000; 525 Pt 1: 135-42.
    • (2000) J. Physiol. , vol.525 , Issue.PART 1 , pp. 135-142
    • Buckler, K.J.1    Williams, B.A.2    Honore, E.3
  • 39
    • 33444462516 scopus 로고    scopus 로고
    • Biophysical properties and metabolic regulation of a TASK-like potassiumn channel in rat carotid body type-1 cells
    • Williams BA, Bucker KJ. Biophysical properties and metabolic regulation of a TASK-like potassiumn channel in rat carotid body type-1 cells. Am J Physiol Lung Cell Mol Physiol 2003.
    • (2003) Am. J. Physiol. Lung Cell Mol. Physiol.
    • Williams, B.A.1    Bucker, K.J.2
  • 41
    • 0035854748 scopus 로고    scopus 로고
    • Combined antisense and pharmacological approaches implicate hTASK as an airway O(2) sensing K(+) channel
    • Hartness ME, Lewis A, Searle GJ, O'Kelly I, Peers C, Kemp PJ. Combined antisense and pharmacological approaches implicate hTASK as an airway O(2) sensing K(+) channel. J Biol Chem 2001; 276: 26499-508.
    • (2001) J. Biol. Chem. , vol.276 , pp. 26499-26508
    • Hartness, M.E.1    Lewis, A.2    Searle, G.J.3    O'Kelly, I.4    Peers, C.5    Kemp, P.J.6
  • 42
    • 0036713459 scopus 로고    scopus 로고
    • Hypoxic depolarization of cerebellar granule neurons by specific inhibition of TASK-1
    • Plant LD, Kemp PJ, Peers C, Henderson Z, Pearson HA. Hypoxic depolarization of cerebellar granule neurons by specific inhibition of TASK-1. Stroke 2002; 33: 2324-8.
    • (2002) Stroke , vol.33 , pp. 2324-2328
    • Plant, L.D.1    Kemp, P.J.2    Peers, C.3    Henderson, Z.4    Pearson, H.A.5
  • 44
    • 1342292264 scopus 로고    scopus 로고
    • Functional Expression of TASK-1/TASK-3 Heteromers in Cerebellar Granule Cells
    • Kang D, Han J, Talley EM, Bayliss DA, Kim D. Functional Expression of TASK-1/TASK-3 Heteromers in Cerebellar Granule Cells. J Physiol 2003.
    • (2003) J. Physiol.
    • Kang, D.1    Han, J.2    Talley, E.M.3    Bayliss, D.A.4    Kim, D.5
  • 45
    • 0037320918 scopus 로고    scopus 로고
    • Background and tandem-pore potassium channels in magnocellular neurosecretory cells of the rat supraoptic nucleus
    • Han J, Gnatenco C, Sladek CD, Kim D. Background and tandem-pore potassium channels in magnocellular neurosecretory cells of the rat supraoptic nucleus. J Physiol 2003; 546: 625-39.
    • (2003) J. Physiol. , vol.546 , pp. 625-639
    • Han, J.1    Gnatenco, C.2    Sladek, C.D.3    Kim, D.4
  • 46
    • 0029986974 scopus 로고    scopus 로고
    • A non-inactivating K+ current sensitive to muscarinic receptor activation in rat cultured cerebellar granule neurons
    • Watkins CS, Mathie A. A non-inactivating K+ current sensitive to muscarinic receptor activation in rat cultured cerebellar granule neurons. J Physiol 1996; 491: 401-12.
    • (1996) J. Physiol. , vol.491 , pp. 401-412
    • Watkins, C.S.1    Mathie, A.2
  • 47
    • 0037112395 scopus 로고    scopus 로고
    • Interaction with 14-3-3 proteins promotes functional expression of the potassium channels TASK-1 and TASK-3
    • Rajan S, Preisig-Muller R, Wischmeyer E, Nehring R, Hanley PJ, Renigunta V, et al. Interaction with 14-3-3 proteins promotes functional expression of the potassium channels TASK-1 and TASK-3. J Physiol 2002; 545: 13-26.
    • (2002) J. Physiol. , vol.545 , pp. 13-26
    • Rajan, S.1    Preisig-Muller, R.2    Wischmeyer, E.3    Nehring, R.4    Hanley, P.J.5    Renigunta, V.6
  • 48
    • 0037112329 scopus 로고    scopus 로고
    • Forward transport 14-3-3 binding overcomes retention in endoplasmic reticulum by dibasic signals
    • O'Kelly I, Butler MH, Zilberberg N, Goldstein SA. Forward transport 14-3-3 binding overcomes retention in endoplasmic reticulum by dibasic signals. Cell 2002; 111: 577-88.
    • (2002) Cell , vol.111 , pp. 577-588
    • O'Kelly, I.1    Butler, M.H.2    Zilberberg, N.3    Goldstein, S.A.4
  • 49
    • 0037009441 scopus 로고    scopus 로고
    • p11, an annexin II subunit, an auxiliary protein associated with the background K+ channel, TASK-1
    • Girard C, Tinel N, Terrenoire C, Romey G, Lazdunski M, Borsotto M. p11, an annexin II subunit, an auxiliary protein associated with the background K+ channel, TASK-1. EMBO J 2002; 21: 4439-48.
    • (2002) EMBO J. , vol.21 , pp. 4439-4448
    • Girard, C.1    Tinel, N.2    Terrenoire, C.3    Romey, G.4    Lazdunski, M.5    Borsotto, M.6
  • 50
    • 0036083696 scopus 로고    scopus 로고
    • Annexins: From structure to function
    • Gerke V, Moss SE. Annexins: from structure to function. Physiol Rev 2002; 82: 331-71.
    • (2002) Physiol. Rev. , vol.82 , pp. 331-371
    • Gerke, V.1    Moss, S.E.2
  • 52
    • 0034596067 scopus 로고    scopus 로고
    • Proton block and voltage gating are potassium-dependent in the cardiac leak channel Kcnk3
    • Lopes CM, Gallagher PG, Buck ME, Butler MH, Goldstein SA. Proton block and voltage gating are potassium-dependent in the cardiac leak channel Kcnk3. J Biol Chem 2000; 275: 16969-78.
    • (2000) J. Biol. Chem. , vol.275 , pp. 16969-16978
    • Lopes, C.M.1    Gallagher, P.G.2    Buck, M.E.3    Butler, M.H.4    Goldstein, S.A.5
  • 54
    • 0041842644 scopus 로고    scopus 로고
    • Contribution of TWIK-related acid-sensitive K+ channel 1 (TASK1) and TASK3 channels to the control of activity modes in thalamocortical neurons
    • Meuth SG, Budde T, Kanyshkova T, Broicher T, Munsch T, Pape HC. Contribution of TWIK-related acid-sensitive K+ channel 1 (TASK1) and TASK3 channels to the control of activity modes in thalamocortical neurons. J Neurosci 2003; 23: 6460-9.
    • (2003) J. Neurosci. , vol.23 , pp. 6460-6469
    • Meuth, S.G.1    Budde, T.2    Kanyshkova, T.3    Broicher, T.4    Munsch, T.5    Pape, H.C.6
  • 55
    • 0033757904 scopus 로고    scopus 로고
    • TASK-1, a two-pore domain K+ channel, is modulated by multiple neurotransmitters in motoneurons
    • Talley EM, Lei Q, Sirois JE, Bayliss DA. TASK-1, a two-pore domain K+ channel, is modulated by multiple neurotransmitters in motoneurons. Neuron 2000; 25: 399-410.
    • (2000) Neuron , vol.25 , pp. 399-410
    • Talley, E.M.1    Lei, Q.2    Sirois, J.E.3    Bayliss, D.A.4
  • 56
    • 0037083421 scopus 로고    scopus 로고
    • Serotonergic raphe neurons express TASK channel transcripts and a TASK-like pH- and halothane-sensitive K+ conductance
    • Washburn CP, Sirois JE, Talley EM, Guyenet PG, Bayliss DA. Serotonergic raphe neurons express TASK channel transcripts and a TASK-like pH- and halothane-sensitive K+ conductance. J Neurosci 2002; 22: 1256-65.
    • (2002) J. Neurosci. , vol.22 , pp. 1256-1265
    • Washburn, C.P.1    Sirois, J.E.2    Talley, E.M.3    Guyenet, P.G.4    Bayliss, D.A.5
  • 57
    • 0031451872 scopus 로고    scopus 로고
    • A primary role for K+ and Na+ efflux in the activation of apoptosis
    • Bortner CD, Hughes FM Jr, Cidlowski JA. A primary role for K+ and Na+ efflux in the activation of apoptosis. J Biol Chem 1997; 272: 32436-42.
    • (1997) J. Biol. Chem. , vol.272 , pp. 32436-32442
    • Bortner, C.D.1    Hughes Jr., F.M.2    Cidlowski, J.A.3
  • 58
    • 0042829363 scopus 로고    scopus 로고
    • Regulation and critical role of potassium homeostasis in apoptosis
    • Yu SP. Regulation and critical role of potassium homeostasis in apoptosis. Prog Neurobiol 2003; 70: 363-86.
    • (2003) Prog. Neurobiol. , vol.70 , pp. 363-386
    • Yu, S.P.1
  • 59
    • 0027483920 scopus 로고
    • Induction of apoptosis in cerebellar granule neurons by low potassium: Inhibition of death by insulin-like growth factor I and cAMP
    • D'Mello SR, Galli C, Ciotti T, Calissano P. Induction of apoptosis in cerebellar granule neurons by low potassium: inhibition of death by insulin-like growth factor I and cAMP. Proc Natl Acad Sci USA 1993; 90: 10989-93.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 10989-10993
    • D'Mello, S.R.1    Galli, C.2    Ciotti, T.3    Calissano, P.4
  • 60
    • 0028924891 scopus 로고
    • Apoptosis in cerebellar granule cells is blocked by high KCl, forskolin, and IGF-1 through distinct mechanisms of action: The involvement of intracellular calcium and RNA synthesis
    • Galli C, Meucci O, Scorziello A, Werge TM, Calissano P, Schettini G. Apoptosis in cerebellar granule cells is blocked by high KCl, forskolin, and IGF-1 through distinct mechanisms of action: the involvement of intracellular calcium and RNA synthesis. J Neurosci 1995; 15: 1172-9.
    • (1995) J. Neurosci. , vol.15 , pp. 1172-1179
    • Galli, C.1    Meucci, O.2    Scorziello, A.3    Werge, T.M.4    Calissano, P.5    Schettini, G.6
  • 61
    • 0029954311 scopus 로고    scopus 로고
    • Potassium deprivation-induced apoptosis of cerebellar granule neurons: A sequential requirement for new mRNA and protein synthesis, ICE-like protease activity, and reactive oxygen species
    • Schulz JB, Weller M, Klockgether T. Potassium deprivation-induced apoptosis of cerebellar granule neurons: a sequential requirement for new mRNA and protein synthesis, ICE-like protease activity, and reactive oxygen species. J Neurosci 1996; 16: 4696-706.
    • (1996) J. Neurosci. , vol.16 , pp. 4696-4706
    • Schulz, J.B.1    Weller, M.2    Klockgether, T.3
  • 62
    • 0036086809 scopus 로고    scopus 로고
    • Apoptosis recruits two-pore domain potassium channels used for homeostatic volume regulation
    • Trimarchi JR, Liu L, Smith PJ, Keefe DL. Apoptosis recruits two-pore domain potassium channels used for homeostatic volume regulation. Am J Physiol Cell Physiol 2002; 282: C588-94.
    • (2002) Am. J. Physiol. Cell Physiol. , vol.282
    • Trimarchi, J.R.1    Liu, L.2    Smith, P.J.3    Keefe, D.L.4
  • 64
    • 0038587789 scopus 로고    scopus 로고
    • Genomic amplification and oncogenic properties of the KCNK9 potassium channel gene
    • Mu D, Chen L, Zhang X, See LH, Koch CM, Yen C, et al. Genomic amplification and oncogenic properties of the KCNK9 potassium channel gene. Cancer Cell 2003; 3: 297-302.
    • (2003) Cancer Cell , vol.3 , pp. 297-302
    • Mu, D.1    Chen, L.2    Zhang, X.3    See, L.H.4    Koch, C.M.5    Yen, C.6
  • 67
    • 0028053408 scopus 로고
    • Potassium channel induction by the Ras/Raf signal transduction cascade
    • Huang Y, Rane SG. Potassium channel induction by the Ras/Raf signal transduction cascade. J Biol Chem 1994; 269: 31183-9.
    • (1994) J. Biol. Chem. , vol.269 , pp. 31183-31189
    • Huang, Y.1    Rane, S.G.2
  • 69
    • 0035804244 scopus 로고    scopus 로고
    • Adaptive regulation of neuronal excitability by a voltage-independent potassium conductance
    • Brickley SG, Revilla V, Cull-Candy SG, Wisden W, Farrant M. Adaptive regulation of neuronal excitability by a voltage-independent potassium conductance. Nature 2001; 409: 88-92.
    • (2001) Nature , vol.409 , pp. 88-92
    • Brickley, S.G.1    Revilla, V.2    Cull-Candy, S.G.3    Wisden, W.4    Farrant, M.5
  • 70
    • 0034814955 scopus 로고    scopus 로고
    • TASK-5, a new member of the tandem-pore K(+) channel family
    • Kim D, Gnatenco C. TASK-5, a new member of the tandem-pore K(+) channel family. Biochem Biophys Res Commun 2001; 284: 923-30.
    • (2001) Biochem. Biophys. Res. Commun. , vol.284 , pp. 923-930
    • Kim, D.1    Gnatenco, C.2
  • 71
    • 0034811790 scopus 로고    scopus 로고
    • TASK-5, a novel member of the tandem pore K+ channel family
    • Ashmole I, Goodwin PA, Stanfield PR. TASK-5, a novel member of the tandem pore K+ channel family. Pflugers Arch 2001; 442: 828-33.
    • (2001) Pflugers Arch. , vol.442 , pp. 828-833
    • Ashmole, I.1    Goodwin, P.A.2    Stanfield, P.R.3
  • 72
    • 0034109513 scopus 로고    scopus 로고
    • Cloning, localisation and functional expression of the human orthologue of the TREK-1 potassium channel
    • Meadows HJ, Benham CD, Cairns W, Glower I, Jennings C, Medhurst AD, et al. Cloning, localisation and functional expression of the human orthologue of the TREK-1 potassium channel. Pflugers Arch 2000; 439: 714-22.
    • (2000) Pflugers Arch. , vol.439 , pp. 714-722
    • Meadows, H.J.1    Benham, C.D.2    Cairns, W.3    Glower, I.4    Jennings, C.5    Medhurst, A.D.6
  • 73
    • 0034625330 scopus 로고    scopus 로고
    • TREK-2, a new member of the mechanosensitive tandem-pore K+ channel family
    • Bang H, Kim Y, Kim D. TREK-2, a new member of the mechanosensitive tandem-pore K+ channel family. Journal of Biological Chemistry 2000; 275: 17412-9.
    • (2000) Journal of Biological Chemistry , vol.275 , pp. 17412-17419
    • Bang, H.1    Kim, Y.2    Kim, D.3
  • 74
    • 0034666296 scopus 로고    scopus 로고
    • Human TREK2, a 2P domain mechano-sensitive K+ channel with multiple regulations by polyunsaturated fatty acids, lysophospholipids, and Gs, Gi, and Gq protein-coupled receptors
    • Lesage F, Terrenoire C, Romey G, Lazdunski M. Human TREK2, a 2P domain mechano-sensitive K+ channel with multiple regulations by polyunsaturated fatty acids, lysophospholipids, and Gs, Gi, and Gq protein-coupled receptors. J Biol Chem 2000; 275: 28398-405.
    • (2000) J. Biol. Chem. , vol.275 , pp. 28398-283405
    • Lesage, F.1    Terrenoire, C.2    Romey, G.3    Lazdunski, M.4
  • 75
    • 0035804774 scopus 로고    scopus 로고
    • Distribution and expression of TREK-1, a two-pore-domain potassium channel, in the adult rat CNS
    • Hervieu GJ, Cluderay JE, Gray CW, Green PJ, Ranson JL, Randall AD, et al. Distribution and expression of TREK-1, a two-pore-domain potassium channel, in the adult rat CNS. Neuroscience 2001; 103: 899-919.
    • (2001) Neuroscience , vol.103 , pp. 899-919
    • Hervieu, G.J.1    Cluderay, J.E.2    Gray, C.W.3    Green, P.J.4    Ranson, J.L.5    Randall, A.D.6
  • 76
    • 0037088820 scopus 로고    scopus 로고
    • Expression pattern and functional characteristics of two novel splice variants of the two-pore-domain potassium channel TREK-2
    • Gu W, Schlichthörl G, Hirsch JR, Engels H, Karschin C, Karschin A, et al. Expression pattern and functional characteristics of two novel splice variants of the two-pore-domain potassium channel TREK-2. J. Physiol. 2002; 539: 657-668.
    • (2002) J. Physiol. , vol.539 , pp. 657-668
    • Gu, W.1    Schlichthörl, G.2    Hirsch, J.R.3    Engels, H.4    Karschin, C.5    Karschin, A.6
  • 77
    • 0036297457 scopus 로고    scopus 로고
    • Molecular basis of the voltage-dependent gating of TREK-1, a mechano-sensitive K(+) channel
    • Maingret F, Honore E, Lazdunski M, Patel AJ. Molecular basis of the voltage-dependent gating of TREK-1, a mechano-sensitive K(+) channel. Biochem Biophys Res Commun 2002; 292: 339-46.
    • (2002) Biochem. Biophys. Res. Commun. , vol.292 , pp. 339-346
    • Maingret, F.1    Honore, E.2    Lazdunski, M.3    Patel, A.J.4
  • 78
    • 0019981853 scopus 로고
    • General anesthetics hyperpolarize neurons in the vertebrate central nervous system
    • Nicoll RA, Madison DV. General anesthetics hyperpolarize neurons in the vertebrate central nervous system. Science 1982; 217: 1055-7.
    • (1982) Science , vol.217 , pp. 1055-1057
    • Nicoll, R.A.1    Madison, D.V.2
  • 79
    • 0028140369 scopus 로고
    • Molecular and cellular mechanisms of general anaesthesia
    • Franks NP, Lieb WR. Molecular and cellular mechanisms of general anaesthesia. Nature 1994; 367: 607-14.
    • (1994) Nature , vol.367 , pp. 607-614
    • Franks, N.P.1    Lieb, W.R.2
  • 80
    • 1842328604 scopus 로고    scopus 로고
    • Sites of alcohol and volatile anaesthetic action on GABA(A) and glycine receptors
    • Mihic SJ, Ye Q, Wick MJ, Koltchine VV. Krasowski MD, Finn SE, et al. Sites of alcohol and volatile anaesthetic action on GABA(A) and glycine receptors. Nature 1997; 389: 385-9.
    • (1997) Nature , vol.389 , pp. 385-389
    • Mihic, S.J.1    Ye, Q.2    Wick, M.J.3    Koltchine, V.V.4    Krasowski, M.D.5    Finn, S.E.6
  • 81
    • 1642457188 scopus 로고    scopus 로고
    • Two-pore-domain K+ channels are a novel target for the anesthetic gases xenon, nitrous oxide, and cyclopropane
    • Gruss M, Bushell TJ, Bright DP, Lieb WR, Mathie A, Franks NP. Two-pore-domain K+ channels are a novel target for the anesthetic gases xenon, nitrous oxide, and cyclopropane. Mol Pharmacol 2004; 65: 443-52.
    • (2004) Mol. Pharmacol. , vol.65 , pp. 443-452
    • Gruss, M.1    Bushell, T.J.2    Bright, D.P.3    Lieb, W.R.4    Mathie, A.5    Franks, N.P.6
  • 83
    • 0033578649 scopus 로고    scopus 로고
    • Mechano- or acid stimulation, two interactive modes of activation of the TREK-1 potassium channel
    • Maingret F, Patel AJ, Lesage F, Lazdunski M, Honore E. Mechano- or acid stimulation, two interactive modes of activation of the TREK-1 potassium channel. J Biol Chem 1999; 274: 26691-6.
    • (1999) J. Biol. Chem. , vol.274 , pp. 26691-26696
    • Maingret, F.1    Patel, A.J.2    Lesage, F.3    Lazdunski, M.4    Honore, E.5
  • 84
    • 0034615923 scopus 로고    scopus 로고
    • Lysophospholipids open the two-pore domain mechano-gated K(+) channels TREK-1 and TRAAK
    • Maingret F, Patel AJ, Lesage F, Lazdunski M, Honore L. Lysophospholipids open the two-pore domain mechano-gated K(+) channels TREK-1 and TRAAK. J Biol Chem 2000; 275: 10128-33.
    • (2000) J. Biol. Chem. , vol.275 , pp. 10128-10133
    • Maingret, F.1    Patel, A.J.2    Lesage, F.3    Lazdunski, M.4    Honore, L.5
  • 88
    • 0034802639 scopus 로고    scopus 로고
    • Localization of TREK-2 K+ channel domains that regulate channel kinetics and sensitivity to pressure, fatty acids and pHi
    • Kim Y, Gnatenco C, Bang H, Kim D. Localization of TREK-2 K+ channel domains that regulate channel kinetics and sensitivity to pressure, fatty acids and pHi. Pflugers Arch 2001; 442: 952-60.
    • (2001) Pflugers Arch. , vol.442 , pp. 952-960
    • Kim, Y.1    Gnatenco, C.2    Bang, H.3    Kim, D.4
  • 90
    • 0037124318 scopus 로고    scopus 로고
    • An intracellular proton sensor commands lipid- and mechano-gating of the K(+) channel TREK-1
    • Honore E, Maingret F, Lazdunski M, Patel AJ. An intracellular proton sensor commands lipid- and mechano-gating of the K(+) channel TREK-1. EMBO J 2002; 21: 2968-76.
    • (2002) EMBO J. , vol.21 , pp. 2968-2976
    • Honore, E.1    Maingret, F.2    Lazdunski, M.3    Patel, A.J.4
  • 91
    • 0037384960 scopus 로고    scopus 로고
    • Acute hypoxia occludes hTREK-1 modulation: Re-evaluation of the potential role of tandem P domain K+ channels in central neuroprotection
    • Miller P, Kemp PJ, Lewis A, Chapman CG, Meadows HJ, Peers C. Acute hypoxia occludes hTREK-1 modulation: re-evaluation of the potential role of tandem P domain K+ channels in central neuroprotection. J Physiol 2003; 548: 31-7.
    • (2003) J. Physiol. , vol.548 , pp. 31-37
    • Miller, P.1    Kemp, P.J.2    Lewis, A.3    Chapman, C.G.4    Meadows, H.J.5    Peers, C.6
  • 92
    • 0742270740 scopus 로고    scopus 로고
    • Polymodal regulation of hTREK1 by pH, arachidonic acid and hypoxia: Physiological impact in acidosis and alkalosis
    • Miller P, Peers C, Kemp PJ. Polymodal regulation of hTREK1 by pH, arachidonic acid and hypoxia: physiological impact in acidosis and alkalosis. Am J Physiol Cell Physiol 2003; 286: C272-282.
    • (2003) Am. J. Physiol. Cell Physiol. , vol.286
    • Miller, P.1    Peers, C.2    Kemp, P.J.3
  • 93
    • 0035903247 scopus 로고    scopus 로고
    • A TREK-1-like potassium, channel in aerial cells inhibited by beta-adrenergic stimulation and activated by volatile anesthetics
    • Terrenoire C, Lauritzen I, Lesage F, Romey G, Lazdunski M. A TREK-1-like potassium, channel in aerial cells inhibited by beta-adrenergic stimulation and activated by volatile anesthetics. Circ Res 2001; 89: 336-42.
    • (2001) Circ. Res. , vol.89 , pp. 336-342
    • Terrenoire, C.1    Lauritzen, I.2    Lesage, F.3    Romey, G.4    Lazdunski, M.5
  • 94
    • 0035941222 scopus 로고    scopus 로고
    • TREK-1 Regulation by Nitric Oxide and cGMP-dependent Protein Kinase. An essential role in smooth MUSCLE inhibitory neurotransmission
    • Koh SD, Monaghan K, Sergeant GP, Ro S, Walker RL, Sanders KM, et al. TREK-1 Regulation by Nitric Oxide and cGMP-dependent Protein Kinase. An essential role in smooth MUSCLE inhibitory neurotransmission. J Biol Chem 2001; 276: 44338-46.
    • (2001) J. Biol. Chem. , vol.276 , pp. 44338-44346
    • Koh, S.D.1    Monaghan, K.2    Sergeant, G.P.3    Ro, S.4    Walker, R.L.5    Sanders, K.M.6
  • 95
    • 0034671854 scopus 로고    scopus 로고
    • Simultaneous activation of p38 MAPK and p42/44 MAPK by ATP stimulates the K+ current ITREK in cardiomyocytes
    • Aimond F, Rauzier JM, Bony C, Vassort G. Simultaneous activation of p38 MAPK and p42/44 MAPK by ATP stimulates the K+ current ITREK in cardiomyocytes. J Biol Chem 2000; 275: 39110-6.
    • (2000) J. Biol. Chem. , vol.275 , pp. 39110-39116
    • Aimond, F.1    Rauzier, J.M.2    Bony, C.3    Vassort, G.4
  • 96
    • 0032526428 scopus 로고    scopus 로고
    • A neuronal two P domain K+ channel stimulated by arachidonic acid and polyunsaturated fatty acids
    • Fink M, Lesage F, Duprat F, Heurteaux C, Reyes R, Fosset M, et al. A neuronal two P domain K+ channel stimulated by arachidonic acid and polyunsaturated fatty acids. EMBO J 1998; 17: 3297-308.
    • (1998) EMBO J. , vol.17 , pp. 3297-3308
    • Fink, M.1    Lesage, F.2    Duprat, F.3    Heurteaux, C.4    Reyes, R.5    Fosset, M.6
  • 97
    • 0035054301 scopus 로고    scopus 로고
    • Synergistic interaction and the role of C-terminus in the activation of TRAAK K+ channels by pressure, free fatty acids and alkali
    • Kim Y, Bang H, Gnatenco C, Kim D. Synergistic interaction and the role of C-terminus in the activation of TRAAK K+ channels by pressure, free fatty acids and alkali. Pflugers Arch 2001; 442: 64-72.
    • (2001) Pflugers Arch. , vol.442 , pp. 64-72
    • Kim, Y.1    Bang, H.2    Gnatenco, C.3    Kim, D.4
  • 98
    • 0242298113 scopus 로고    scopus 로고
    • Heterogeneous expression of TASK-3 and TRAAK in rat paraganglionic cells
    • Yamamoto Y, Taniguchi K. Heterogeneous expression of TASK-3 and TRAAK in rat paraganglionic cells. Histochem Cell Biol 2003; 120: 335-9.
    • (2003) Histochem. Cell Biol. , vol.120 , pp. 335-339
    • Yamamoto, Y.1    Taniguchi, K.2
  • 99
    • 0037144152 scopus 로고    scopus 로고
    • TASK-1, TASK-2, TASK-3 and TRAAK immunoreactivities in the rat carotid body
    • Yamamoto Y, Kummer W, Atoji Y, Suzuki Y. TASK-1, TASK-2, TASK-3 and TRAAK immunoreactivities in the rat carotid body. Brain Res 2002; 950: 304-7.
    • (2002) Brain Res. , vol.950 , pp. 304-307
    • Yamamoto, Y.1    Kummer, W.2    Atoji, Y.3    Suzuki, Y.4
  • 100
    • 0037097488 scopus 로고    scopus 로고
    • Cloning of two transcripts, HKT4.1a and HKT4.1b, from the human two-pore K+ channel gene KCNK4. Chromosomal localization, tissue distribution and functional expression
    • Ozaita A, Vega-Saenz de Miera E. Cloning of two transcripts, HKT4.1a and HKT4.1b, from the human two-pore K+ channel gene KCNK4. Chromosomal localization, tissue distribution and functional expression. Brain Res Mol Brain Res 2002; 102: 18-27.
    • (2002) Brain Res. Mol. Brain Res. , vol.102 , pp. 18-27
    • Ozaita, A.1    Vega-Saenz de Miera, E.2
  • 101
    • 0023154905 scopus 로고
    • Neuronal inhibition by the peptide FMRFamide involves opening of S K+ channels
    • Belardetti F, Kandel ER, Siegelbaum SA. Neuronal inhibition by the peptide FMRFamide involves opening of S K+ channels. Nature 1987; 325: 153-6.
    • (1987) Nature , vol.325 , pp. 153-156
    • Belardetti, F.1    Kandel, E.R.2    Siegelbaum, S.A.3
  • 102
    • 0028055164 scopus 로고
    • FMRFamide and membrane stretch as activators of the Aplysia S-channel
    • Vandorpe DH, Small DL, Dabrowski AR, Morris CE. FMRFamide and membrane stretch as activators of the Aplysia S-channel. Biophys J 1994; 66: 46-58.
    • (1994) Biophys. J. , vol.66 , pp. 46-58
    • Vandorpe, D.H.1    Small, D.L.2    Dabrowski, A.R.3    Morris, C.E.4
  • 103
    • 0024384172 scopus 로고
    • Potassium channels in cardiac cells activated by arachidonic acid and phospholipids
    • Kim D, Clapham DE. Potassium channels in cardiac cells activated by arachidonic acid and phospholipids. Science 1989; 244: 1174-6.
    • (1989) Science , vol.244 , pp. 1174-1176
    • Kim, D.1    Clapham, D.E.2
  • 104
    • 0027094162 scopus 로고
    • A mechanosensitive K channel in heart cells: Activation by arachidonic acid
    • Kim D. A mechanosensitive K channel in heart cells: activation by arachidonic acid. J Gen Physiol 1992; 100: 1-20.
    • (1992) J. Gen. Physiol. , vol.100 , pp. 1-20
    • Kim, D.1
  • 105
    • 0038554223 scopus 로고    scopus 로고
    • Dynamic properties of stretch-activaed K+ channels in adult rat atrial myocytes
    • Niu W, Sachs F. Dynamic properties of stretch-activaed K+ channels in adult rat atrial myocytes. Prog Biophys Mol Biol 2003; 82: 121-35.
    • (2003) Prog. Biophys. Mol. Biol. , vol.82 , pp. 121-135
    • Niu, W.1    Sachs, F.2
  • 106
    • 0024411914 scopus 로고
    • Arachidonic acid and other fatty acids directly activate potassium channels in smooth muscle cells
    • Ordway RW, Walsh JV Jr, Singer JJ. Arachidonic acid and other fatty acids directly activate potassium channels in smooth muscle cells. Science 1989; 244: 1176-9.
    • (1989) Science , vol.244 , pp. 1176-1179
    • Ordway, R.W.1    Walsh Jr., J.V.2    Singer, J.J.3
  • 107
    • 0031887553 scopus 로고    scopus 로고
    • Modulation of K+ channels by arachidonic acid in T84 cells. II. Activation of a Ca(2+)-independent K+ channel
    • Devor DC, Frizzell RA. Modulation of K+ channels by arachidonic acid in T84 cells. II. Activation of a Ca(2+)-independent K+ channel. Am J Physiol 1998; 274: C149-60.
    • (1998) Am. J. Physiol. , vol.274
    • Devor, D.C.1    Frizzell, R.A.2
  • 108
    • 0037147301 scopus 로고    scopus 로고
    • An ACTH- and ATP-regulated background K+ channel in adrenocortical cells is TREK-1
    • Enyeart JJ, Xu L, Danthi S, Enyeart JA. An ACTH- and ATP-regulated background K+ channel in adrenocortical cells is TREK-1. J Biol Chem 2002; 277: 49186-99.
    • (2002) J. Biol. Chem. , vol.277 , pp. 49186-49199
    • Enyeart, J.J.1    Xu, L.2    Danthi, S.3    Enyeart, J.A.4
  • 109
    • 0038237029 scopus 로고    scopus 로고
    • Corticotropin induces the expression of TREK-3 mRNA and K+ current in adrenocortical cells
    • Enyeart JA, Danthi S, Enyeart JJ. Corticotropin induces the expression of TREK-3 mRNA and K+ current in adrenocortical cells. Mol Pharmacol 2003; 64: 132-42.
    • (2003) Mol. Pharmacol. , vol.64 , pp. 132-142
    • Enyeart, J.A.1    Danthi, S.2    Enyeart, J.J.3
  • 110
    • 0034015102 scopus 로고    scopus 로고
    • The neuroprotective agent riluzole activates the two P domain K(+) channels TREK-1 and TRAAK
    • Duprat F, Lesage F, Patel AJ, Fink M, Romey G, Lazdunski M. The neuroprotective agent riluzole activates the two P domain K(+) channels TREK-1 and TRAAK. Mol Pharmacol 2000; 57: 906-12.
    • (2000) Mol. Pharmacol. , vol.57 , pp. 906-912
    • Duprat, F.1    Lesage, F.2    Patel, A.J.3    Fink, M.4    Romey, G.5    Lazdunski, M.6
  • 111
    • 0035895804 scopus 로고    scopus 로고
    • The neuroprotective agent sipatrigine (BW619C89) potently inhibits the human tandem pore-domain K(+) channels TREK-1 and TRAAK
    • Meadows HJ, Chapman CG, Duckworth DM, Kelsell RE, Murdock PR, Nasir S, et al. The neuroprotective agent sipatrigine (BW619C89) potently inhibits the human tandem pore-domain K(+) channels TREK-1 and TRAAK. Brain Res 2001; 892: 94-101.
    • (2001) Brain Res. , vol.892 , pp. 94-101
    • Meadows, H.J.1    Chapman, C.G.2    Duckworth, D.M.3    Kelsell, R.E.4    Murdock, P.R.5    Nasir, S.6
  • 113
    • 1642450667 scopus 로고    scopus 로고
    • Alterations in the expression of lipid and mechano-gated two-pore domain potassium channel genes in rat brain following chronic cerebral ischemia
    • Xu X, Pan Y, Wang, X. Alterations in the expression of lipid and mechano-gated two-pore domain potassium channel genes in rat brain following chronic cerebral ischemia. Brain Res Mol Brain Res 2004; 120: 205-9.
    • (2004) Brain Res. Mol. Brain Res. , vol.120 , pp. 205-209
    • Xu, X.1    Pan, Y.2    Wang, X.3
  • 114
    • 0037155476 scopus 로고    scopus 로고
    • Functional expression of TREK-2 K+ channel in cultured rat brain astrocytes
    • Gnatenco C, Han J, Snyder AK, Kim D. Functional expression of TREK-2 K+ channel in cultured rat brain astrocytes. Brain Res 2002; 931: 56-67.
    • (2002) Brain Res. , vol.931 , pp. 56-67
    • Gnatenco, C.1    Han, J.2    Snyder, A.K.3    Kim, D.4
  • 115
    • 3342981356 scopus 로고    scopus 로고
    • TREK-1, a K(+) channel involved in neuroprotection and general anesthesia
    • (April) (published on line)
    • Heurteaux C, Guy N, Laigle C, Blondeau N, Duprat F, Mazzuca M, et al. TREK-1, a K(+) channel involved in neuroprotection and general anesthesia. EMBO J 2004 (April): 1-15 (published on line).
    • (2004) EMBO J , pp. 1-15
    • Heurteaux, C.1    Guy, N.2    Laigle, C.3    Blondeau, N.4    Duprat, F.5    Mazzuca, M.6
  • 116
    • 0032553319 scopus 로고    scopus 로고
    • Cloning and expression of a novel pH-sensitive two pore domain K+ channel from human kidney
    • Reyes R, Duprat F, Lesage F, Fink M, Salinas M, Farman N, et al. Cloning and expression of a novel pH-sensitive two pore domain K+ channel from human kidney. J Biol Chem 1998; 273: 30863-9.
    • (1998) J. Biol. Chem. , vol.273 , pp. 30863-30869
    • Reyes, R.1    Duprat, F.2    Lesage, F.3    Fink, M.4    Salinas, M.5    Farman, N.6
  • 118
    • 0035831101 scopus 로고    scopus 로고
    • Characterization of TASK-4, a novel member of the pH-sensitive, two-pore domain potassium channel family
    • Decher N, Maier M, Dittrich W, Gassenhuber J, Bruggemann A, Busch AE, et al. Characterization of TASK-4, a novel member of the pH-sensitive, two-pore domain potassium channel family. FEBS Lett 2001; 192: 84-9.
    • (2001) FEBS Lett. , vol.192 , pp. 84-89
    • Decher, N.1    Maier, M.2    Dittrich, W.3    Gassenhuber, J.4    Bruggemann, A.5    Busch, A.E.6
  • 119
    • 0041386484 scopus 로고    scopus 로고
    • Functional Properties of Four Splice Variants of a Human Pancreatic Tandem-Pore K+ channel, TALK-1
    • Han J, Kang D, Kim D. Functional Properties of Four Splice Variants of a Human Pancreatic Tandem-Pore K+ channel, TALK-1. Am J Physiol Cell Physiol 2003; 285: C529-538.
    • (2003) Am. J. Physiol. Cell Physiol. , vol.285
    • Han, J.1    Kang, D.2    Kim, D.3
  • 120
    • 0034122584 scopus 로고    scopus 로고
    • Volatile anesthetics activate the human tandem pore domain baseline K+ channel KCNK5
    • Gray AT, Zhao BB, Kindler CH, Winegar BD, Mazurek MJ, Xu J, et al. Volatile anesthetics activate the human tandem pore domain baseline K+ channel KCNK5. Anesthesiology 2000; 92: 1722-30.
    • (2000) Anesthesiology , vol.92 , pp. 1722-1730
    • Gray, A.T.1    Zhao, B.B.2    Kindler, C.H.3    Winegar, B.D.4    Mazurek, M.J.5    Xu, J.6
  • 121
    • 1342280334 scopus 로고    scopus 로고
    • Segment-specific expression of 2P domain potassium channel genes in human nephron
    • Levy DI, Velazquez H, Goldstein SA, Bockenhauer D. Segment-specific expression of 2P domain potassium channel genes in human nephron. Kidney Int 2004; 65: 918-26.
    • (2004) Kidney Int. , vol.65 , pp. 918-926
    • Levy, D.I.1    Velazquez, H.2    Goldstein, S.A.3    Bockenhauer, D.4
  • 122
    • 0037203783 scopus 로고    scopus 로고
    • Localization of the tandem pore domain K+ channel KCNK5 (TASK-2) in the rat central nervous system
    • Gabriel A, Abdallah M, Yost CS, Winegar BD, Kindler CH. Localization of the tandem pore domain K+ channel KCNK5 (TASK-2) in the rat central nervous system. Brain Res Mol Brain Res 2002; 98: 153-63.
    • (2002) Brain Res. Mol. Brain Res. , vol.98 , pp. 153-163
    • Gabriel, A.1    Abdallah, M.2    Yost, C.S.3    Winegar, B.D.4    Kindler, C.H.5
  • 123
    • 0035900681 scopus 로고    scopus 로고
    • Modulation of the two-pore domain acid-sensitive K+ channel TASK-2 (KCNK5) by changes in cel volume
    • Niemeyer MI, Cid LP, Barros LF, Sepulveda FV. Modulation of the two-pore domain acid-sensitive K+ channel TASK-2 (KCNK5) by changes in cel volume. J Biol Chem 2001; 276: 43166-74.
    • (2001) J. Biol. Chem. , vol.276 , pp. 43166-43174
    • Niemeyer, M.I.1    Cid, L.P.2    Barros, L.F.3    Sepulveda, F.V.4
  • 124
    • 0041859581 scopus 로고    scopus 로고
    • Role of TASK2 Potassium Channels Regarding Volume Regulation in Primary Cultures of Mouse Proximal Tubules
    • Barriere H, Belfodil R, Rubera I, Tauc M, Lesage F, Poujeol C, et al. Role of TASK2 Potassium Channels Regarding Volume Regulation in Primary Cultures of Mouse Proximal Tubules. J Gen Physiol 2003; 122: 177-190.
    • (2003) J. Gen. Physiol. , vol.122 , pp. 177-190
    • Barriere, H.1    Belfodil, R.2    Rubera, I.3    Tauc, M.4    Lesage, F.5    Poujeol, C.6
  • 125
    • 1342324088 scopus 로고    scopus 로고
    • Single-channel properties and pH sensitivity of two-pore domain K+ channels of the TALK family
    • Kang DW, Kim D. Single-channel properties and pH sensitivity of two-pore domain K+ channels of the TALK family. Biochem Biophys Res Commun 2004; 315: 836-844.
    • (2004) Biochem. Biophys. Res. Commun. , vol.315 , pp. 836-844
    • Kang, D.W.1    Kim, D.2
  • 126
  • 127
    • 0032944029 scopus 로고    scopus 로고
    • Local anesthetic inhibition of baseline potassium channels with two pore domains in tandem
    • Kindler CH, Yest CS, Gray AT. Local anesthetic inhibition of baseline potassium channels with two pore domains in tandem. Anesthesiology 1999; 90: 1092-102.
    • (1999) Anesthesiology , vol.90 , pp. 1092-1102
    • Kindler, C.H.1    Yest, C.S.2    Gray, A.T.3
  • 128
    • 0034280244 scopus 로고    scopus 로고
    • Tandem pore domain K channels: An important site of volatile anesthetic action?
    • Yost CS. Tandem pore domain K channels: an important site of volatile anesthetic action? Curr Drug Targets 2000; 1: 207-17.
    • (2000) Curr. Drug Targets , vol.1 , pp. 207-217
    • Yost, C.S.1
  • 129
    • 0037407328 scopus 로고    scopus 로고
    • Mutation of KCNK5 or Kir3.2 potassium channels in mice does not change minimum alveolar anesthetic concentration
    • table of contents
    • Gerstin KM, Gong DH, Abdallah M, Winegar BD, Eger EI, 2nd. Gray AT. Mutation of KCNK5 or Kir3.2 potassium channels in mice does not change minimum alveolar anesthetic concentration. Anesth Analg 2003; 96: 1345-9, table of contents.
    • (2003) Anesth. Analg. , vol.96 , pp. 1345-1349
    • Gerstin, K.M.1    Gong, D.H.2    Abdallah, M.3    Winegar, B.D.4    Eger II, E.I.5    Gray, A.T.6
  • 131
    • 0036181995 scopus 로고    scopus 로고
    • Pharmacological characterization of a non-inactivating outward current observed in mouse cerebellar Purkinje neurones
    • Bushell T, Clarke C, Mathie A, Robertson B. Pharmacological characterization of a non-inactivating outward current observed in mouse cerebellar Purkinje neurones. Br J Pharmacol 2002; 135: 705-12.
    • (2002) Br. J. Pharmacol. , vol.135 , pp. 705-712
    • Bushell, T.1    Clarke, C.2    Mathie, A.3    Robertson, B.4
  • 133
    • 0033597220 scopus 로고    scopus 로고
    • Cloning of a new mouse two-P domain channel subunit and a human homologue with a unique pore structure
    • Salinas M, Reyes R, Lesage F, Fosset M, Heurteaux C, Romey G, et al. Cloning of a new mouse two-P domain channel subunit and a human homologue with a unique pore structure. J Biol Chem 1999; 274: 11751-60.
    • (1999) J. Biol. Chem. , vol.274 , pp. 11751-11760
    • Salinas, M.1    Reyes, R.2    Lesage, F.3    Fosset, M.4    Heurteaux, C.5    Romey, G.6
  • 134
    • 0034739805 scopus 로고    scopus 로고
    • Genomic organization and chromosomal localization of the murine 2 P domain potassium channel gene Kcnk8: Conservation of gene structure in 2 P domain potassium channels
    • Bockenhauer D, Nimmakayalu MA, Ward DC, Goldstein SA, Gallagher PG. Genomic organization and chromosomal localization of the murine 2 P domain potassium channel gene Kcnk8: conservation of gene structure in 2 P domain potassium channels. Gene 2000; 261: 365-72.
    • (2000) Gene , vol.261 , pp. 365-372
    • Bockenhauer, D.1    Nimmakayalu, M.A.2    Ward, D.C.3    Goldstein, S.A.4    Gallagher, P.G.5
  • 135
    • 0029099458 scopus 로고
    • A new family of outwardly rectifying potassium channel proteins with two pore domains in tandem
    • Ketchum KA, Joiner WJ, Sellers AJ, Kaczmarek LK, Goldstein SA. A new family of outwardly rectifying potassium channel proteins with two pore domains in tandem. Nature 1995; 376: 690-5.
    • (1995) Nature , vol.376 , pp. 690-695
    • Ketchum, K.A.1    Joiner, W.J.2    Sellers, A.J.3    Kaczmarek, L.K.4    Goldstein, S.A.5
  • 136
    • 0030064010 scopus 로고    scopus 로고
    • A pH-sensitive yeast outward rectifier K+ channel with two pore domains and novel gating properties
    • Lesage F, Guillemare E, Fink M, Duprat F, Lazdunski M, Romey G, et al. A pH-sensitive yeast outward rectifier K+ channel with two pore domains and novel gating properties. J Biol Chem 1996; 271: 4183-7.
    • (1996) J. Biol. Chem. , vol.271 , pp. 4183-4187
    • Lesage, F.1    Guillemare, E.2    Fink, M.3    Duprat, F.4    Lazdunski, M.5    Romey, G.6
  • 137
    • 0029975979 scopus 로고    scopus 로고
    • The S. cerevisiae outwardly-rectifying potassium channel (DUK1) identifies a new family of channels with duplicated pore domains
    • Reid JD, Lukas W, Shafaatian R, Bertl A, Scheurmann-Kettner C, Guy HR, et al. The S. cerevisiae outwardly-rectifying potassium channel (DUK1) identifies a new family of channels with duplicated pore domains. Receptors Channels 1996; 4: 51-62.
    • (1996) Receptors Channels , vol.4 , pp. 51-62
    • Reid, J.D.1    Lukas, W.2    Shafaatian, R.3    Bertl, A.4    Scheurmann-Kettner, C.5    Guy, H.R.6
  • 138
    • 0030919991 scopus 로고    scopus 로고
    • New structure and function in plant K+ channels: KCO1, an outward rectifier with a steep Ca2+ dependency
    • Czempinski K, Zimmermann S, Ehrhardt T, Muller-Rober B. New structure and function in plant K+ channels: KCO1, an outward rectifier with a steep Ca2+ dependency. EMBO J 1997; 16: 2565-75.
    • (1997) EMBO J , vol.16 , pp. 2565-2575
    • Czempinski, K.1    Zimmermann, S.2    Ehrhardt, T.3    Muller-Rober, B.4
  • 141
    • 0035369624 scopus 로고    scopus 로고
    • Immunity to K1 killer toxin: Internal TOK1 blockade
    • Sesti F, Shih TM, Nikolaeva N, Goldstein SA. Immunity to K1 killer toxin: internal TOK1 blockade. Cell 2001; 105: 637-44.
    • (2001) Cell , vol.105 , pp. 637-644
    • Sesti, F.1    Shih, T.M.2    Nikolaeva, N.3    Goldstein, S.A.4
  • 142
    • 0029804030 scopus 로고    scopus 로고
    • ORK1, a potassium-selective leak channel with two pore domains cloned from Drosophila melanogaster by expression in Saccharomyces cerevisiae
    • Goldstein SN, Price LA, Rosenthal DN, Pausch MH. ORK1, a potassium-selective leak channel with two pore domains cloned from Drosophila melanogaster by expression in Saccharomyces cerevisiae. Proc Nat Acad Sci USA 1996; 93: 13256-13261.
    • (1996) Proc. Nat. Acad. Sci. USA , vol.93 , pp. 13256-13261
    • Goldstein, S.N.1    Price, L.A.2    Rosenthal, D.N.3    Pausch, M.H.4
  • 144
    • 0029861307 scopus 로고    scopus 로고
    • Fight potassium channel families revealed by the C. elegans Genome project
    • Wei A, Jegla T, Salkoff L. Fight potassium channel families revealed by the C. elegans Genome project. Neuropharmacology 1996; 35: 805-829.
    • (1996) Neuropharmacology , vol.35 , pp. 805-829
    • Wei, A.1    Jegla, T.2    Salkoff, L.3
  • 145
    • 0034667562 scopus 로고    scopus 로고
    • Mutants of a temperature-sensitive two-P domain potassium channel
    • Kunkel MT, Johnstone DB, Thomas JH, Salkoff L. Mutants of a temperature-sensitive two-P domain potassium channel. J Neurosci 2000; 20: 7517-24.
    • (2000) J. Neurosci. , vol.20 , pp. 7517-7524
    • Kunkel, M.T.1    Johnstone, D.B.2    Thomas, J.H.3    Salkoff, L.4
  • 146
    • 0141885134 scopus 로고    scopus 로고
    • sup-9, sup-10, and unc-93 may encode components of a two-pore K+ channel that coordinates muscle contraction in Caenorhabditis elegans
    • de la Cruz IP, Levin JZ, Cummins C, Anderson P, Horvitz HR. sup-9, sup-10, and unc-93 may encode components of a two-pore K+ channel that coordinates muscle contraction in Caenorhabditis elegans. J Neurosci 2003; 23: 9133-45.
    • (2003) J. Neurosci. , vol.23 , pp. 9133-9145
    • de la Cruz, I.P.1    Levin, J.Z.2    Cummins, C.3    Anderson, P.4    Horvitz, H.R.5
  • 147
    • 0032884148 scopus 로고    scopus 로고
    • Mutations in the yeast two pore K+ channel YKC1 identify functional differences between the pore domains
    • Vergani P, Blatt MR. Mutations in the yeast two pore K+ channel YKC1 identify functional differences between the pore domains. FEBS Lett 1999; 458: 285-91.
    • (1999) FEBS Lett. , vol.458 , pp. 285-291
    • Vergani, P.1    Blatt, M.R.2
  • 148
    • 0033031497 scopus 로고    scopus 로고
    • Potassium uptake through the TOK1 K+ channel in the budding yeast
    • Fairman C, Zhou X, Kung C. Potassium uptake through the TOK1 K+ channel in the budding yeast. J Membr Biol 1999; 168: 149-57.
    • (1999) J. Membr. Biol. , vol.168 , pp. 149-157
    • Fairman, C.1    Zhou, X.2    Kung, C.3
  • 149
    • 0343812059 scopus 로고    scopus 로고
    • Random mutagenesis reveals a region important for gating of the yeast K+ channel Ykc1
    • Loukin SH, Valliant B, Zhou XL, Spalding EP, Kung C, Saimi Y. Random mutagenesis reveals a region important for gating of the yeast K+ channel Ykc1. EMBO J 1997; 16: 4817-25.
    • (1997) EMBO J. , vol.16 , pp. 4817-4825
    • Loukin, S.H.1    Valliant, B.2    Zhou, X.L.3    Spalding, E.P.4    Kung, C.5    Saimi, Y.6
  • 150
    • 0037085449 scopus 로고    scopus 로고
    • Splitting the two pore domains from TOK1 results in two cationic channels with novel functional properties
    • Saldana C, Naranjo D, Coria R, Pena A, Vaca L. Splitting the two pore domains from TOK1 results in two cationic channels with novel functional properties. J Biol Chem 2002; 277: 4797-805.
    • (2002) J. Biol. Chem. , vol.277 , pp. 4797-4805
    • Saldana, C.1    Naranjo, D.2    Coria, R.3    Pena, A.4    Vaca, L.5
  • 151
    • 0035923762 scopus 로고    scopus 로고
    • KCNKO: Opening and closing the 2-P-domain potassium leak channel entails "C-type" gating of the outer pore
    • Zilberberg N, Ilan N, Goldstein SA. KCNKO: opening and closing the 2-P-domain potassium leak channel entails "C-type" gating of the outer pore. Neuron 2001; 32: 635-48.
    • (2001) Neuron , vol.32 , pp. 635-648
    • Zilberberg, N.1    Ilan, N.2    Goldstein, S.A.3
  • 152
    • 0034783033 scopus 로고    scopus 로고
    • GYGD pore motifs in neighbouring potassium channel subunits interact to determine ion selectivity
    • Chapman ML, Krovetz HS, VanDongen AM. GYGD pore motifs in neighbouring potassium channel subunits interact to determine ion selectivity. J Physiol 2001; 530: 21-33.
    • (2001) J. Physiol. , vol.530 , pp. 21-33
    • Chapman, M.L.1    Krovetz, H.S.2    VanDongen, A.M.3
  • 153
    • 0031907110 scopus 로고    scopus 로고
    • Sequence and function of the two P domain potassium channels: Implications of an emerging superfamily
    • Goldstein SAN, Wang K-W, Ilan N, Pausch MH. Sequence and function of the two P domain potassium channels: implications of an emerging superfamily. J Mol Med 1998; 76: 13-20.
    • (1998) J. Mol. Med. , vol.76 , pp. 13-20
    • Goldstein, S.A.N.1    Wang, K.-W.2    Ilan, N.3    Pausch, M.H.4
  • 154
    • 0033679959 scopus 로고    scopus 로고
    • Molecular and functional properties of two-pore-domain potassium channels
    • Lesage F, Lazdunski M. Molecular and functional properties of two-pore-domain potassium channels. Am J Physiol Renal Physiol 2000; 279: F793-801.
    • (2000) Am. J. Physiol. Renal. Physiol. , vol.279
    • Lesage, F.1    Lazdunski, M.2
  • 156
    • 0035371189 scopus 로고    scopus 로고
    • Properties and modulation of mammalian 2P domain K+ channels
    • Patel AJ, Honore E. Properties and modulation of mammalian 2P domain K+ channels. Trends Neurosci 2001; 24: 339-46.
    • (2001) Trends Neurosci. , vol.24 , pp. 339-346
    • Patel, A.J.1    Honore, E.2
  • 158
    • 0037310538 scopus 로고    scopus 로고
    • Two-pore-Domain (KCNK) potassium channels: Dynamic roles in neuronal function
    • Talley EM, Sirois JE, Lei Q, Bayliss DA. Two-pore-Domain (KCNK) potassium channels: dynamic roles in neuronal function. Neuroscientist 2003; 9: 46-56.
    • (2003) Neuroscientist , vol.9 , pp. 46-56
    • Talley, E.M.1    Sirois, J.E.2    Lei, Q.3    Bayliss, D.A.4
  • 159
    • 0037246960 scopus 로고    scopus 로고
    • Pharmacology of neuronal background potassium channels
    • Lesage F. Pharmacology of neuronal background potassium channels. Neuropharmacology 2003; 44: 1-7.
    • (2003) Neuropharmacology , vol.44 , pp. 1-7
    • Lesage, F.1
  • 160
    • 0345118935 scopus 로고    scopus 로고
    • Fatty acid-sensitive two-pore domain K(+) channels
    • Kim D. Fatty acid-sensitive two-pore domain K(+) channels. Trends Pharmacol Sci 2003; 24: 648-54.
    • (2003) Trends Pharmacol. Sci. , vol.24 , pp. 648-654
    • Kim, D.1
  • 162
    • 1642383007 scopus 로고    scopus 로고
    • Simulating the interactions of toxins with K+ channels
    • Huang X, Liu H, Cui M, Fu W, Yu K, Chen K, et al. Simulating the interactions of toxins with K+ channels. Curr Pharm Design 2004; 10(9): 1057-67.
    • (2004) Curr. Pharm. Design , vol.10 , Issue.9 , pp. 1057-1067
    • Huang, X.1    Liu, H.2    Cui, M.3    Fu, W.4    Yu, K.5    Chen, K.6
  • 163
    • 3242892255 scopus 로고    scopus 로고
    • Testosterone action on the Sertoli cell membrane: A KIR6.x channel related effect
    • Wassermann GF, Loss ES. Testosterone action on the Sertoli cell membrane: a KIR6.x channel related effect. Curr Pharm Design 2004; 10(21): 2649-56.
    • (2004) Curr. Pharm. Design , vol.10 , Issue.21 , pp. 2649-2656
    • Wassermann, G.F.1    Loss, E.S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.