TWIK-1, a ubiquitous human weakly inward rectifying K+ channel with a novel structure

EMBO Journal

Volumn 15, Issue 5, 1996, Pages 1004-1011

  Lesage, Florian ^a   Guillemare, Eric ^a   Fink, Michel ^a   Duprat, Fabrice ^a   Lazdunski, Michel ^a   Romey, Georges ^a   Barhanin, Jacques ^a  

^a INSTITUT DE PHARMACOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

Author keywords

Background conductance; Cloning; pH; PKC

Indexed keywords

BARIUM ION; CARRIER PROTEIN; MAGNESIUM ION; MESSENGER RNA; POTASSIUM CHANNEL; PROTEIN KINASE C; QUINIDINE; QUININE;

ACIDIFICATION; ANIMAL CELL; ARTICLE; CAENORHABDITIS ELEGANS; CELL MEMBRANE DEPOLARIZATION; HUMAN; HUMAN TISSUE; NONHUMAN; NUCLEOTIDE SEQUENCE; OOCYTE; PRIORITY JOURNAL; PROTEIN DOMAIN; SEQUENCE HOMOLOGY; TRANSPORT KINETICS; XENOPUS;

ANIMALIA; CAENORHABDITIS ELEGANS; CINCHONA PUBESCENS; MAMMALIA;

EID: 0029871919     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1002/j.1460-2075.1996.tb00437.x     Document Type: Article

References (44)

1. Aldrich, R.W. (1994) Potassium channels - new channel subunits are a turn-off. Curr. Biol., 4, 839-840.
2. Altschul, S F., Gish, W., Miller, W., Myers, E.W. and Lipman, D.J. (1990) Basic local alignment search tool. J. Mol. Biol., 215, 403-410.
3. + channel activity in Xenopus oocytes Proc. Natl Acad. Sci. USA, 92, 6092-6096.
4. Auffray, C. et al. (1995) IMAGE: Integrated molecular analysis of the human genome and its expression. C. R. Acad. Sci., III, Sci vie, 318, 263-272
5. Barres, B.A., Chun, L.L.Y. and Corey, D.P (1990) Ion channels in vertebrate glia. Annu. Rev Neurosci., 13, 441-474.
6. Bear, C.E., Davison, J.S. and Shaffer, E.A. (1988) Intracellular pH influences the resting membrane potential of isolated rat hepatocytes Biochim Biophys Acta, 944, 113-120
7. Betz, H. (1990) Homology and analogy in transmembrane channel design: lessons from synaptic membrane proteins Biochemistry, 29, 3591-3599
8. Bezanilla, F and Stefani, E. (1994) Voltage-dependent gating of ionic channels. Annu. Rev. Biophys. Biomol Struct., 23, 819-846.
9. Bradley, J., Li, J., Davidson, N., Lester, H.A. and Zinn, K. (1994) Heteromeric olfactory cyclic nucleotide-galed channels: a subunit that confers increased sensitivity to cAMP. Proc. Natl Acad. Sci. USA, 91, 8890-8894.
10. Browne, D.L., Gancher, S.T., Nutt, T.G., Brunt, E.R.P , Smith, E A , Kramer, P. and Litt, M. (1994) Episodic ataxia/myokymia syndrome is associated with point mutations in the human potassium channel gene, KCNA1. Nature Genet., 8, 136-140.
11. + channel is made of three homologous subunits. Nature, 367, 463-467.
12. Curran, M E , Splawski, I., Timothy, K.W., Vincent, G.M., Green, E.D. and Keating, M.T. (1995) A molecular basis for cardiac arrhythmia: HERO mutations cause long QT syndrome. Cell, 80, 795-803.
13. Doupnik, C.A., Davidson, N. and Lester, H.A. (1995) The inward rectifier potassium channel family. Curr. Opin. Neurobiol., 5, 268-277.
14. + channel activity of neuronal and cardiac g-protein-activated inward rectifiers. Biochem Biophys. Res. Commun., 212, 657-663.
15. + channel KvI.2. Biochemistry, 31, 12463-12468.
16. Guillemare, E., Lazdunski, M. and Honore, E. (1995) Glibenclamide opens ATP-sensitive potassium channels in Xenopus oocyte follicular cells during metabolic stress. Mol. Pharmacol., 47, 588-594.
17. + channel signature sequence. Biophys. J., 66, 1061-1067.
18. Hille, B. (1992) Ionic Channels of Excitable Membranes. 2nd edn. Sinauer, Sunderland, MA.
19. Isom, L.L., Dejongh, K.S. and Catterall, W.A. (1994) Auxiliary subunits of voltage-gated ion channels. Neuron, 12, 1183-1194.
20. Jan, L.Y. and Jan, Y.N. (1994) Potassium channels and their evolving gates. Nature, 371, 119-122.
21. Ketchum, K A., Joiner, W.J , Sellers, A.J., Kaczmarek, L.K. and Goldstein, S.A.N. (1995) A new family of outwardly rectifying potassium channel proteins with two pore domains in tandem. Nature, 376, 690-695.
22. + channels arc activated by g beta gamma subunits and function as heteromultimers. Proc. Natl Acad Sci. USA, 92, 6542-6546.
23. Koh, D S., Jonas, P , Brau, M.E. and Vogel, W. (1992) A TEA-insensitive flickering potassium channel active around the resting potential in myelinated nerve. J. Membrane Biol., 130, 149-162
24. +-channel proteins. Nature, 374, 135-141.
25. + channel with two P domains and novel gating properties. J. Biol. Chem., in press.
26. 2+-induced regulation of ion channel and MAP kinase functions. Nature, 376, 737-745.
27. Levitan, I.B. (1994) Modulation of ion channels by protein phosphorylation and dephosphorylation. Annu. Rev Physiol., 56, 193-212.
28. Lewis, R.S. and Cahalan, M.D. (1995) Potassium and calcium channels in lymphocytes. Annu. Rev. Immunol., 13, 623-653.
29. + channel - a new channel type with homologies to Caenorhabditis elegans degenerins. FEBS Lett., 318, 95-99
30. + channel are differently regulated by aldosterone J. Biol. Chem., 269, 13736-13739.
31. + channel result in corresponding decreases in gating charge. Neuron, 8, 531-540.
32. + channel. Nature, 371, 243-246.
33. Mackinnon, R. (1995) Pore loops, an emerging theme in ion channel structure. Neuron, 14, 889-892
34. + channel. Annu. Rev. Physiol., 53, 289-298.
35. 2+-dependent inward rectification of ROMK1 potassium channels expressed in Xenopus oocytes. J Physiol. (London), 476, 399-409.
36. + pore structure revealed by receptor cysteines at inner and outer surfaces. Neuron. 14, 1055-1063.
37. Pedersen, P L. and Carafoli, E. (1987) I. Ubiquity, properties, and significance to cell function. Trends Biol. Sci., 12, 146-189.
38. Pongs, O. (1992) Molecular biology of voltage-dependent potassium channels. Physiol. Rev., 72, S69-88.
39. Pongs, O. (1993) Structure-function studies on the pore of potassium channels. J. Membrane Biol., 136, 1-8.
40. + channels altered by presence of beta-subunit. Nature, 369, 289-294.
41. + channels. Neurosciences, 25, 729-749.
42. + channels conserved in flies, mice and humans. Trends Neurosci., 15, 161-166.
43. Seeburg, P H. (1993) The TINS/TIPS lecture - the molecular biology of mammalian glutamate receptor channels Trends Neurosci., 16, 359-365.
44. + channel. Neuron. 14, 1047-1054.