O2 sensing by recombinant TWIK-related halothane-inhibitable K+ channel-1 background K+ channels heterologously expressed in human embryonic kidney cells

Neuroscience

Volumn 135, Issue 4, 2005, Pages 1087-1094

  Campanucci, V A ^a,c   Brown, S T ^a   Hudasek, K ^a   O'Kelly, I M ^a   Nurse, C A ^a   Fearon, I M ^a,b  

^a MCMASTER UNIVERSITY   (Canada)

^b UNIVERSITY OF MANCHESTER   (United Kingdom)

^c MCGILL UNIVERSITY   (Canada)

Author keywords

Acute hypoxia; Arecombinant expression; HEK293; THIK 1 K+ channels

Indexed keywords

ARACHIDONIC ACID; ARSENOSOBENZENE; DIPHENYLIODONIUM SALT; ENZYME INHIBITOR; HALOTHANE; MYXOTHIAZOL; OXYGEN; POTASSIUM CHANNEL; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; ROTENONE; SODIUM CYANIDE; KCNK13 PROTEIN, HUMAN; RECOMBINANT PROTEIN; TANDEM PORE DOMAIN POTASSIUM CHANNEL;

ARTICLE; BRAIN ISCHEMIA; CELL FUNCTION; CONTROLLED STUDY; EMBRYO; GLOSSOPHARYNGEAL NERVE; HUMAN; HUMAN CELL; HYPOXIA; KIDNEY CELL; MEMBRANE DEPOLARIZATION; NERVE CELL; PATHOLOGY; PHYSIOLOGY; POTASSIUM CURRENT; PRIORITY JOURNAL; PROTEIN EXPRESSION; SENSITIVITY ANALYSIS; CELL LINE; CELL MEMBRANE POTENTIAL; GENETIC TRANSFECTION; METABOLISM; PATCH CLAMP; PATHOPHYSIOLOGY;

CELL LINE; HUMANS; HYPOXIA-ISCHEMIA, BRAIN; MEMBRANE POTENTIALS; OXYGEN; PATCH-CLAMP TECHNIQUES; POTASSIUM CHANNELS, TANDEM PORE DOMAIN; RECOMBINANT PROTEINS; TRANSFECTION;

EID: 26244462635     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2005.07.009     Document Type: Article

References (23)

1. K.J. Buckler, B.A. Williams, E. Honore An oxygen-, acid- and anaesthetic-sensitive TASK-like background potassium channel in rat arterial chemoreceptor cells J Physiol 525 2000 135 142
2. + conductance J Physiol 548 2003 731 743
3. 2-sensitive neurons from the rat glossopharyngeal nerve Neuroscience 132 2005 437 451
4. + channels role of the Kv1.2 subunit in mediating the hypoxic response J Physiol 524 2000 783 793
5. S.A. Goldstein, D. Bockenhauer, I. O'Kelly, N. Zilberberg Potassium leak channels and the KCNK family of two-P-domain subunits Nat Rev Neurosci 2 2001 175 184
6. O.P. Hamill, A. Marty, E. Neher, B. Sakmann, F.J. Sigworth Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches Pflugers Arch 391 1981 85 100
7. B. Hohler, B. Mayer, W. Kummer Nitric oxide synthase in the rat carotid body and carotid sinus Cell Tissue Res 276 1994 559 564
8. + channel TASK-1 Am J Physiol 286 2004 C391 C397
9. 2 in the control of neuronal excitability? J Cell Mol Med 8 2004 38 44
10. + channel Biochem Biophys Res Commun 285 2001 1290 1294
11. C.M. Lopes, N. Zilberberg, S.A.N. Goldstein Block of Kcnk3 by protons. Evidence that 2 -P-domain potassium channel subunits function as homodimers J Biol Chem 276 2001 24449 24452
12. 2 in type I chemoreceptor cells Science 241 1988 580 582
13. J. Lopez-Barneo, R. Pardal, P. Ortega-Saenz Cellular mechanism of oxygen sensing Annu Rev Physiol 63 2001 259 287
14. + channels in central neuroprotection J Physiol 548 2003 31 37
15. 2 sensing by airway chemoreceptor-derived cells Protein kinase C activation reveals functional evidence for involvement of NADPH oxidase J Biol Chem 275 2000 7684 7692
16. + current in a human neuroepithelial body-derived cell line Am J Physiol 276 1999 L96 L104
17. 2 sensitivity to Kv4.2 but not to Shaker channels J Gen Physiol 113 1999 897 907
18. L.D. Plant, P.J. Kemp, C. Peers, Z. Henderson, H.A. Pearson Hypoxic depolarization of cerebellar granule neurons by specific inhibition of TASK-1 Stroke 33 2002 2324 2328
19. N.R. Prabhakar, G.K. Kumar, C.H. Chang, F.H. Agani, M.A. Haxhiu Nitric oxide in the sensory function of the carotid body Brain Res 625 1993 16 22
20. + channels J Biol Chem 276 2001 7302 7311
21. Z.Z. Wang, L.J. Stensaas, B.G. Dinger, S. Fidone Nitric oxide mediates chemoreceptor inhibition in the cat carotid body Neuroscience 65 1995 217 229
22. S.E. Williams, P. Wootton, H.S. Mason, J. Bould, D.E. Iles, D. Riccardi, C. Peers, P.J. Kemp Hemoxygenase-2 is an oxygen sensor for a calcium-sensitive potassium channel Science 306 2004 2093 2097
23. C.N. Wyatt, K.J. Buckler The effect of mitochondrial inhibitors on membrane currents in isolated neonatal rat carotid body type I cells J Physiol 556 2004 175 191