Parameters of protection against ultraviolet radiation-induced skin cell damage

Journal of Cellular Physiology

Volumn 220, Issue 2, 2009, Pages 277-284

  Cao, Cong ^a   Wan, Yinsheng ^b  

^a BROWN UNIVERSITY   (United States)

^b PROVIDENCE COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AQUAPORIN 3; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; MAMMALIAN TARGET OF RAPAMYCIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; PROTEIN P53; STRESS ACTIVATED PROTEIN KINASE; ADENYLATE KINASE; MULTIPROTEIN COMPLEX; PROTEIN KINASE; REACTIVE OXYGEN METABOLITE;

APOPTOSIS; CELL DAMAGE; CELL DEATH; CELLULAR STRESS RESPONSE; CUTANEOUS PARAMETERS; ENZYME ACTIVATION; ENZYME MODIFICATION; HUMAN; KERATINOCYTE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RADIATION CARCINOGENESIS; RADIATION INJURY; SHORT SURVEY; SIGNAL TRANSDUCTION; SKIN CANCER; SKIN CARCINOGENESIS; SKIN INJURY; SKIN PROTECTION; SOLAR RADIATION; ULTRAVIOLET RADIATION; ANIMAL; METABOLISM; PATHOLOGY; PHYSIOLOGY; PROTEIN PROCESSING; RADIATION EXPOSURE; REVIEW; SKIN; SKIN TUMOR;

ADENYLATE KINASE; ANIMALS; APOPTOSIS; ENZYME ACTIVATION; HUMANS; MITOGEN-ACTIVATED PROTEIN KINASES; MULTIPROTEIN COMPLEXES; PROTEIN KINASES; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTO-ONCOGENE PROTEINS C-AKT; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; SKIN; SKIN NEOPLASMS; TUMOR SUPPRESSOR PROTEIN P53; ULTRAVIOLET RAYS;

EID: 67649363838     PISSN: 00219541     EISSN: None     Source Type: Journal    
DOI: 10.1002/jcp.21780     Document Type: Short Survey

References (89)

1. Arad M, Seidman CE, Seidman JG. 2007. AMP-activated protein kinase in the heart: Role during health and disease. Circ Res 100:474-488.
2. Bellemere G, Von Stetten O, Oddos T. 2008. Retinoic acid increases aquaporin 3 expression in normal human skin. J Invest Dermatol 128:542-548.
3. Bhaskar PT, Hay N. 2007. The two TORCs and Akt. Dev Cell 12:487-502.
4. Bode AM, Dong Z. 2003. Mitogen-activated protein kinase activation in UV-induced signal transduction. Sci STKE 2003:RE2.
5. Bouras T, Fu M, Sauve AA, Wang F, Quong AA, Perkins ND, Hay RT, Gu W, Pestell RG. 2005. SIRTI deacetylation and repression of p300 involves lysine residues 1020/1024 within the cell cycle regulatory domain I. J Biol Chem 280:10264-10276.
6. Brunet A, Bonni A, Zigmond MJ, Lin MZ, Juo P, Hu LS, Anderson MJ, Arden KC, Blenis J, Greenberg ME. 1999. Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor. Cell 96:857-868.
7. Brunet A, Sweeney LB, Sturgill JF, Chua KF, Greer PL, Lin Y, Tran H, Ross SE, Mostoslavsky R, Cohen HY, Hu LS, Cheng HL, Jedrychowski MP, Gygi SP, Sinclair DA, Alt FW, Greenberg ME. 2004. Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase. Science 303:2011-2015.
8. Bulavin DV, Saito S, Hollander MC, Sakaguchi K, Anderson CW, Appella E, Fornace AJ, Jr. 1999. Phosphorylation of human p53 by p38 kinase coordinates N-terminal phosphorylation and apoptosis in response to UV radiation. EMBO J 18:6845-6854.
9. Cao C, Sun Y, Healey S, Bi Z, Hu G, Wan S, Kouttab N, Chu W, Wan Y. 2006. EGFR-mediated expression of aquaporin-3 is involved in human skin fibroblast migration. Biochem J 400:225-234.
10. Cao C, Healey S, Amaral A, Lee-Couture A, Wan S, Kouttab N, Chu W, Wan Y. 2007. ATP-sensitive potassium channel:A novel target for protection against UV-induced human skin cell damage. J Cell Physiol 212:252-263.
11. Cao C, Lu S, Jiang Q, Wang WJ, Song X, Kivlin R, Wallin B, Bagdasarian A, Tamakloe T, Chu WM, Marshall J, Kouttab N, Xu A, Wan Y. 2008a. EGFR activation confers protections against UV-induced apoptosis in cultured mouse skin dendritic cells. Cell Signal 20:1830-1838.
12. Cao C, Lu S, Kivlin R, Wallin B, Card E, Bagdasarian A, Tamakloe T, Chu WM, Guan KL, Wan Y. 2008b. AMP-activated protein kinase contributes to UV- and H2O2-induced apoptosis in human skin keratinocytes. J Biol Chem 283:28897-28908.
13. Cao C, Lu S, Kivlin R, Wallin B, Card E, Bagdasarian A, Tamakloe T, Wang WJ, Song X, Chu WM, Kouttab N, Xu A, Wan Y. 2008c. SIRT1 confers protection against UVB- and H(2)O(2)-induced cell death via modulation of p53 and JNKin cultured skin keratinocytes. J Cell Mol Med. [Epub ahead of print].
14. Cao C, Wan S, Jiang Q, Amaral A, Lu S, Hu G, Bi Z, Kouttab N, Chu W, Wan Y. 2008d. All-trans retinoic acid attenuates ultraviolet radiation-induced down-regulation of aquaporin-3 and water permeability in human keratinocytes. J Cell Physiol 215:506-516.
15. Carling D. 2004. The AMP-activated protein kinase cascade - A unifying system for energy control. Trends Biochem Sci 29:18-24.
16. Danno K, Horio T, Takigawa M, Imamura S. 1984. Role of oxygen intermediates in UV-induced epidermal cell injury. J Invest Dermatol 83:166-168.
17. Edinger AL, Thompson CB. 2002. Akt maintains cell size and survival by increasing mTOR-dependent nutrient uptake. Mol Biol Cell 13:2276-2288.
18. Elias PM. 2005. Stratum corneum defensive functions: An integrated view. J Invest Dermatol 125:183-200.
19. Facchinetti V, Ouyang W, Wei H, Soto N, Lazorchak A, Gould C, Lowry C, Newton AC, Mao Y, Miao RQ, Sessa WC, Qin J, Zhang P, Su B, Jacinto E. 2008. The mammalian target of rapamycin complex 2 controls folding and stability of Akt and protein kinase C. EMBO J 27:1932-1943.
20. Fasano WJ, Manning LA, Green JW. 2002. Rapid integrity assessment of rat and human epidermal membranes for in vitro dermal regulatory testing: Correlation of electrical resistance with tritiated water permeability. Toxicol In Vitro 16:731-740.
21. Fisher GJ, Talwar HS, Lin J, Lin P, McPhillips F, Wang Z, Li X, Wan Y, Kang S, Voorhees JJ. 1998. Retinoic acid inhibits induction of c-Jun protein by ultraviolet radiation that occurs subsequent to activation of mitogen-activated protein kinase pathways in human skin in vivo. J Clin Invest 101:1432-1440.
22. Fisher GJ, Talwar HS, Lin J, Voorhees JJ. 1999. Molecular mechanisms of photoaging in human skin in vivo and their prevention by all-trans retinoic acid. Photochem Photobiol 69:154-157.
23. Frias MA, Thoreen CC, Jaffe JD, Schroder W, Sculley T, Carr SA, Sabatini DM. 2006. mSin1 is necessary for Akt/PKB phosphorylation, and its isoforms define three distinct mTORC2s. Curr Biol 16:1865-1870.
24. Gu W, Roeder RG. 1997. Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain. Cell 90:595-606.
25. Guertin DA, Stevens DM, Thoreen CC, Burds AA, Kalaany NY, Moffat J, Brown M, Fitzgerald KJ, Sabatini DM. 2006. Ablation in mice of the mTORC components raptor, rictor, or mLST8 reveals that mTORC2 is required for signaling to Akt-FOXO and PKCalpha, but not S6K1. Dev Cell 11:859-871.
26. Guertin DA, Stevens DM, Saitoh M, Kinkel S, Crosby K, Sheen JH, Mullholland DJ, Magnuson MA, Wu H, Sabatini DM. 2009. mTOR complex 2 is required for the development of prostate cancer induced by Pten loss in mice. Cancer Cell 15:148-159.
27. Hara M, Verkman AS. 2003. Glycerol replacement corrects defective skin hydration, elasticity, and barrier function in aquaporin-3-deficient mice. Proc Natl Acad Sci USA 100:7360-7365.
28. Hara-Chikuma M, Verkman AS. 2005. Aquaporin-3 functions as a glycerol transporter in mammalian skin. Biol Cell 97:479-486.
29. Hresko RC, Mueckler M. 2005. mTOR.RICTOR is the Ser473 kinase for Akt/protein kinase B in 3T3-L1 adipocytes. J Biol Chem 280:40406-40416.
30. Huang RP, Wu JX, Fan Y, Adamson ED. 1996. UV activates growth factor receptors via reactive oxygen intermediates. J Cell Biol 133:211-220.
31. Huang C, Li J, Ke Q, Leonard SS, Jiang BH, Zhong XS, Costa M, Castranova V, Shi X. 2002. Ultraviolet-induced phosphorylation of p70(S6K) at Thr(389) and Thr(421)/Ser(424) involves hydrogen peroxide and mammalian target of rapamycin but not Akt and atypical protein kinase C. Cancer Res 62:5689-5697.
32. Inoki K, Zhu T, Guan KL. 2003. TSC2 mediates cellular energy response to control cell growth and survival. Cell 115:577-590.
33. Inoki K, Ouyang H, Li Y, Guan KL. 2005. Signaling by target of rapamycin proteins in cell growth control. Microbiol Mol Biol Rev 69:79-100.
34. Inoki K, Ouyang H, Zhu T, Lindvall C, Wang Y, Zhang X, Yang Q, Bennett C, Harada Y, Stankunas K, Wang CY, He X, MacDougald OA, You M, Williams BO, Guan KL. 2006. TSC2 integrates Wnt and energy signals via a coordinated phosphorylation by AMPK and GSK3 to regulate cell growth. Cell 126:955-968.
35. Jones RG, Plas DR, Kubek S, Buzzai M, Mu J, Xu Y, Birnbaum MJ, Thompson CB. 2005. AMP-activated protein kinase induces a p53-dependent metabolic checkpoint. Mol Cell 18:283-293.
36. Jun ES, Kim YS, Yoo, Roh HJ, Jung JS. 2001. Changes in expression of ion channels and aquaporins mRNA during differentiation in normal human nasal epithelial cells. Life Sci 68:827-840.
37. Kaeberlein M, McVey M, Guarente L. 1999. The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms. Genes Dev 13:2570-2580.
38. Kahn BB, Alquier T, Carling D, Hardie DG. 2005. AMP-activated protein kinase: Ancient energy gauge provides clues to modern understanding of metabolism. Cell Metab 1:15-25.
39. Kang S. 2005. The mechanism of action of topical retinoids. Cutis 75:10-13; discussion 13.
40. Kang S, Chung JH, Lee JH, Fisher GJ, Wan YS, Duell EA, Voorhees JJ. 2003. Topical N-acetyl cysteine and genistein prevent ultraviolet-light-induced signaling that leads to photoaging in human skin in vivo. J Invest Dermatol 120:835-841.
41. Kim DH, Sarbassov DD, Ali SM, King JE, Latek RR, Erdjument-Bromage H, Tempst P, Sabatini DM. 2002.mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery. Cell 110:163-175.
42. Kim WH, Lee JW, Suh YH, Lee HJ, Lee SH, Oh YK, Gao B, Jung MH. 2007. AICAR potentiates ROS production induced by chronic high glucose: Roles of AMPK in pancreatic beta-cell apoptosis. Cell Signal 19:791-805.
43. Kligman LH, Kligman AM. 1986. The nature of photoaging: Its prevention and repair. Photodermatology 3:215-227.
44. Kobet E, Zeng X, Zhu Y, Keller D, Lu H. 2000. MDM2 inhibits p300-mediated p53 acetylation and activation by forming a ternary complex with the twoproteins. ProcNatl Acad Sci USA 97:12547-12552.
45. Lambert PF, Kashanchi F, Radonovich MF, Shiekhattar R, Brady JN. 1998. Phosphorylation of p53 serine 15 increases interaction with CBP. J Biol Chem 273:33048-33053.
46. Li S, Sonenberg N, Gingras AC, Peterson M, Avdulov S, Polunovsky VA, Bitterman PB. 2002. Translational control of cell fate: Availability of phosphorylation sites on translational repressor 4E-BP1 governs its proapoptotic potency. Mol Cell Biol 22:2853-2861.
47. Li AG, Piluso LG, Cai X, Gadd BJ, Ladurner AG, Liu X. 2007a. An acetylation switch in p53 mediates holo-TFIID recruitment. Mol Cell 28:408-421.
48. Li LH, Wu LJ, Tashiro SI, Onodera S, Uchiumi F, Ikejima T. 2007b. Activation of the SIRTI pathway and modulation of the cell cycle were involved in silymarin's protection against UV-induced A375-S2 cell apoptosis. J Asian Nat Prod Res 9:245-252.
49. Liotta LA, Steeg PS, Stetler-Stevenson WG. 1991. Cancer metastasis and angiogenesis: An imbalance of positive and negative regulation. Cell 64:327-336.
50. Luo J, Nikolaev AY, Imai S, Chen D, Su F, Shiloh A, Guarente L, Gu W. 2001. Negative control of p53 by Sir2alpha promotes cell survival under stress. Cell 107:137-148.
51. Ma T, Hara M, Sougrat R, Verbavatz JM, Verkman AS. 2002. Impaired stratum corneum hydration in mice lacking epidermal water channel aquaporin-3. J Biol Chem 277:17147-17153.
52. Mamane Y, Petroulakis E, LeBacquer O, Sonenberg N. 2006. mTOR, translation initiation and cancer. Oncogene 25:6416-6422.
53. Masri J, Bernath A, Martin J, Jo OD, Vartanian R, Funk A, Gera J. 2007. mTORC2 activity is elevated in gliomas and promotes growth and cell motility via overexpression of rictor. Cancer Res 67:11712-11720.
54. Mayo LD, Donner DB. 2001. A phosphatidylinositol 3-kinase/Akt pathway promotes translocation of Mdm2 from the cytoplasm to the nucleus. Proc Natl Acad Sci USA 98:11598-11603.
55. Meunier L. 1999. Ultraviolet light and dendritic cells. Eur J Dermatol 9:269-275.
56. Motta MC, Divecha N, Lemieux M, Kamel C, Chen D, Gu W, Bultsma Y, McBurney M, Guarente L. 2004. Mammalian SIRT1 represses forkhead transcription factors. Cell 116:551-563.
57. Mungamuri SK, Yang X, Thor AD, Somasundaram K. 2006. Survival signaling by Notch1: Mammalian target of rapamycin (mTOR)-dependent inhibition of p53. Cancer Res 66:4715-4724.
58. Nakagawa S, Ohtani T, Mizuashi M, Mollah ZU, Ito Y, Tagami H, Aiba S. 2004. p38 mitogen-activated protein kinase mediates dual role of ultraviolet B radiation in induction of maturation and apoptosis of monocyte-derived dendritic cells. J Invest Dermatol 123:361-370.
59. Nakakoshi M, Morishita Y, Usui K, Ohtsuki M, Ishibashi K. 2006. Identification of a keratinocarcinoma cell line expressing AQP3. Biol Cell 98:95-100.
60. Ongusaha PP, Qi HH, Raj L, Kim YB, Aaronson SA, Davis RJ, Shi Y, Liao JK, Lee SW. 2008. Identification of ROCK1 as an upstream activator of the JIP-3 to JNK signaling axis in response to UVB damage. Sci Signal 1:ra14.
61. Panner A, James CD, Berger MS, Pieper RO. 2005. mTOR controls FLIPS translation and TRAIL sensitivity in glioblastoma multiforme cells. Mol Cell Biol 25:8809-8823.
62. Picard F, Kurtev M, Chung N, Topark-Ngarm A, Senawong T, Machado De Oliveira R, Leid M, McBurney MW, Guarente L. 2004. Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-gamma. Nature 429:771-776.
63. Polunovsky VA, Gingras AC, Sonenberg N, Peterson M, Tan A, Rubins JB, Manivel JC, Bitterman PB. 2000. Translational control of the antiapoptotic function of Ras. J Biol Chem 275:24776-24780.
64. Proud CG. 2004. Role of mTOR signalling in the control of translation initiation and elongation by nutrients. Curr Top Microbiol Immunol 279:215-244.
65. Proud CG. 2005. The eukaryotic initiation factor 4E-binding proteins and apoptosis. Cell Death Differ 12:541-546.
66. Rattan R, Giri S, Singh AK, Singh I. 2005. 5-Aminoimidazole-4- carboxamide-1-beta-Dribofuranoside inhibits cancer cell proliferation in vitro and in vivo via AMP-activated protein kinase. J Biol Chem 280:39582-39593.
67. Rodgers JT, Lerin C, Haas W, Gygi SP, Spiegelman BM, Puigserver P. 2005. Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1. Nature 434:113-118.
68. Rosette C, Karin M. 1996. Ultraviolet light and osmotic stress: Activation of the JNK cascade through multiple growth factor and cytokine receptors. Science 274:1194-1197.
69. Roupe G. 2001. Skin of the aging human being. Lakartidningen 98:1091-1095.
70. Ruderman NB, Keller C, Richard AM, Saha AK, Luo Z, Xiang X, Giralt M, Ritov VB, Menshikova EV, Kelley DE, Hidalgo J, Pedersen BK, Kelly M. 2006. Interleukin-6 regulation of AMP-activated protein kinase. Potential role in the systemic response to exercise and prevention of the metabolic syndrome. Diabetes 55:S48-S54.
71. Sabatini DM. 2006. mTOR and cancer: Insights into a complex relationship. Nat Rev Cancer 6:729-734.
72. Sarbassov DD, Guertin DA, Ali SM, Sabatini DM. 2005. Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex. Science 307:1098-1101.
73. Shiota C, Woo JT, Lindner J, Shelton KD, Magnuson MA. 2006. Multiallelic disruption of the rictor gene in mice reveals that mTOR complex 2 is essential for fetal growth and viability. Dev Cell 11:583-589.
74. Siliciano JD, Canman CE, Taya Y, Sakaguchi K, Appella E, Kastan MB. 1997. DNA damage induces phosphorylation of the amino terminus of p53. Genes Dev 11:3471-3481.
75. Sugatani T, Hruska KA. 2005. Akt1/Akt2 andmammalian target of rapamycin/Bim play critical roles in osteoclast differentiation and survival, respectively, whereas Akt is dispensable for cell survival in isolated osteoclast precursors. J Biol Chem 280:3583-3589.
76. Sun Y, Yuan J, Liu H, Shi Z, Baker K, Vuori K, Wu J, Feng GS. 2004. Role of Gab1 in UV-induced c-Jun NH2-terminal kinase activation and cell apoptosis. Mol Cell Biol 24:1531-1539.
77. Tang Y, Zhao W, Chen Y, Zhao Y, Gu W. 2008. Acetylation is indispensable for p53 activation. Cell 133:612-626.
78. Towler MC, Hardie DG. 2007. AMP-activated protein kinase in metabolic control and insulin signaling. Circ Res 100:328-341.
79. Umeda J, Sano S, Kogawa K, Motoyama N, Yoshikawa K, Itami S, Kondoh G, Watanabe T, Takeda J. 2003. In vivo cooperation between Bcl-xL and the phosphoinositide 3-kinase-Akt signaling pathway for the protection of epidermal keratinocytes from apoptosis. FASEB J 17:610-620.
80. Varani J, Warner RL, Gharaee-Kermani M, Phan SH, Kang S, Chung JH, Wang ZQ, Datta SC, Fisher GJ, Voorhees JJ. 2000. Vitamin A antagonizes decreased cell growth and elevated collagen-degrading matrix metalloproteinases and stimulates collagen accumulation in naturally aged human skin. J Invest Dermatol 114:480-486.
81. Vaziri H, Dessain SK, Ng Eaton E, Imai SI, Frye RA, Pandita TK, Guarente L, Weinberg RA. 2001. hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase. Cell 107:149-159.
82. Vega F, Medeiros LJ, Leventaki V, Atwell C, Cho-Vega JH, Tian L, Claret FX, Rassidakis GZ. 2006. Activation ofmammalian target of rapamycin signaling pathway contributes to tumor cell survival in anaplastic lymphoma kinase-positive anaplastic large cell lymphoma. Cancer Res 66:6589-6597.
83. Verkman AS. 2005. More than just water channels: Unexpected cellular roles of aquaporins. J Cell Sci 118:3225-3232.
84. Vogelstein B, Lane D, Levine AJ. 2000. Surfing the p53 network. Nature 408:307-310.
85. Wan YS, Wang ZQ, Shao Y, Voorhees JJ, Fisher GJ. 2001. Ultraviolet irradiation activates PI 3-kinase/AKT survival pathway via EGF receptors in human skin in vivo. Int J Oncol 18:461-466.
86. Wang HQ, Quan T, He T, Franke TF, Voorhees JJ, Fisher GJ. 2003. Epidermal growth factor receptor-dependent, NF-kappaB-independent activation of the phosphatidylinositol 3-kinase/Akt pathway inhibits ultraviolet irradiation-induced caspases-3, -8, and -9 in human keratinocytes. J Biol Chem 278:45737-45745.
87. Weiss JS, Ellis CN, Headington JT, Voorhees JJ. 1988. Topical tretinoin in the treatment of aging skin. J Am Acad Dermatol 19:169-175.
88. Xiang X, Saha AK, Wen R, Ruderman NB, Luo Z. 2004. AMP-activated protein kinase activators can inhibit the growth of prostate cancer cells by multiple mechanisms. Biochem Biophys Res Commun 321:161-167.
89. Yoon MJ, Lee GY, Chung JJ, Ahn YH, Hong SH, Kim JB. 2006. Adiponectin increases fatty acid oxidation in skeletal muscle cells by sequential activation of AMP-activated protein kinase, p38 mitogen-activated protein kinase, and peroxisome proliferator-activated receptor alpha. Diabetes 55:2562-2570.