Epidermal Growth Factor Receptor-dependent, NF-κB-independent Activation of the Phosphatidylinositol 3-Kinase/Akt Pathway Inhibits Ultraviolet Irradiation-induced Caspases-3, -8, and -9 in Human Keratinocytes

Journal of Biological Chemistry

Volumn 278, Issue 46, 2003, Pages 45737-45745

  Wang, Hui Qin ^a   Quan, Taihao ^a   He, Tianyuan ^a   Franke, Thomas F ^b   Voorhees, John J ^a   Fisher, Gary J ^a,c  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b Och Spine at New York Presbyterian Hospitals   (United States)

^c UNIVERSITY OF MICHIGAN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; CHEMICAL ACTIVATION; DNA; ENZYME INHIBITION; ENZYME KINETICS; GROWTH KINETICS; IRRADIATION; ULTRAVIOLET RADIATION;

APOPTOSIS; FLOW CYTOMETRY; PHOSPHORYLATIONS;

BIOCHEMISTRY;

2 MORPHOLINO 8 PHENYLCHROMONE; CASPASE 3; CASPASE 8; CASPASE 9; CYTOCHROME C; DNA FRAGMENT; EPIDERMAL GROWTH FACTOR RECEPTOR; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PD 169540; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; RECEPTOR BLOCKING AGENT; UNCLASSIFIED DRUG; WORTMANNIN;

ADENOVIRUS; APOPTOSIS; ARTICLE; CELL NUCLEUS; CELL PROTECTION; CELL SURVIVAL; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; KERATINOCYTE; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; ULTRAVIOLET IRRADIATION; WESTERN BLOTTING;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ADENOVIRIDAE; APOPTOSIS; CASPASE 3; CASPASE 8; CASPASE 9; CASPASES; CHROMONES; CYTOSOL; DNA FRAGMENTATION; ENZYME INHIBITORS; ENZYME-LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; HUMANS; KERATINOCYTES; MICROSCOPY, FLUORESCENCE; MORPHOLINES; NF-KAPPA B; OXIDATIVE STRESS; PHOSPHORYLATION; PRECIPITIN TESTS; RECEPTOR, EPIDERMAL GROWTH FACTOR; ULTRAVIOLET RAYS;

ADENOVIRIDAE;

EID: 0242580735     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M300574200     Document Type: Article

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