MDM2 inhibits p300-mediated p53 acetylation and activation by forming a ternary complex with the two proteins

Proceedings of the National Academy of Sciences of the United States of America

Volumn 97, Issue 23, 2000, Pages 12547-12552

  Kobet, Eric ^a   Zeng, Xiaoya ^a   Zhu, Yong ^a   Keller, David ^a   Lu, Hua ^a  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; HISTONE; PROTEIN MDM2; PROTEIN P300; PROTEIN P53; PROTEIN P73;

ACETYLATION; AMINO TERMINAL SEQUENCE; ANIMAL CELL; CARBOXY TERMINAL SEQUENCE; CARCINOMA CELL; CONFERENCE PAPER; CONTROLLED STUDY; DNA DAMAGE; GENE ACTIVATION; GENETIC TRANSCRIPTION; HELA CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DNA BINDING; PROTEIN EXPRESSION; PROTEIN METABOLISM; PROTEIN PROTEIN INTERACTION; TESTIS CARCINOMA; TUMOR SUPPRESSOR GENE;

ANIMALIA;

EID: 0033732303     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.97.23.12547     Document Type: Article

References (51)

1. Ko, L. J. & Prives, C. (1996) Genes Dev. 10, 1054-1072.
2. Levine, A. J. (1997) Cell 88, 323-331.
3. Giaccia, A. J. & Kastan, M. B. (1998) Genes Dev. 12, 2973-2983.
4. Chehab, N. H., Malikzay, A., Appel, M. & Halazonetis, T. D. (2000) Genes Dev. 14, 278-288.
5. Fuchs, S. Y., Adler, V., Pincus, M. R. & Ronai, Z. (1998) Proc. Natl. Acad. Sci. USA 95, 10541-10546.
6. Hirao, A., Kong, Y. Y., Matsuoka, S., Wakeham, A., Ruland, J., Yoshida, H., Liu, D., Elledge, S. J. & Mak, T. W. (2000) Science 287, 1824-1827.
7. Kapoor, M. & Lozano, G. (1998) Proc. Natl. Acad. Sci. USA 95, 2834-2837.
8. Keller, D., Zeng, X., Li, X., Kapoor, M., Iordanov, M. S., Taya, Y., Lozano, G., Magun, B. & Lu, H. (1999) Biochem. Biophys. Res. Commun. 261, 464-471.
9. Lu, H., Taya, Y., Ikeda, M. & Levine, A. J. (1998) Proc. Natl. Acad. Sci. USA 95, 6399-6402.
10. Shieh, S. Y., Ikeda, M., Taya, Y. & Prives, C. (1997) Cell 91, 325-334.
11. Siliciano, J. D., Canman, C. E., Taya, Y., Sakaguchi, K., Appella, E. & Kastan, M. B. (1997) Genes Dev. 11, 3471-3481.
12. Shieh, S. Y., Ahn, J., Tamai, K., Taya, Y. & Prives, C. (2000) Genes Dev. 14, 289-300.
13. Unger, T., Juven-Gershon, T., Moallem, E., Berger, M., Vogt Sionov, R., Lozano, G., Oren, M. & Haupt, Y. (1999) EMBO J. 18, 1805-1814.
14. Wright, J. A., Keegan, K. S., Herendeen, D. R., Bentley, N. J., Carr, A. M., Hoekstra, M. F. & Concannon, P. (1998) Proc. Natl. Acad. Sci. USA 95, 7445-7450.
15. Sakaguchi, K., Herrera, J. E., Saito, S., Miki, T., Bustin, M., Vassilev, A., Anderson, C. W. & Appella, E. (1998) Genes Dev. 12, 2831-2841.
16. Gu, W. & Roeder, R. G. (1997) Cell 90, 595-606.
17. Avantaggiati, M. L., Ogryzko, V., Gardner, K., Giordano, A., Levine, A. S. & Kelly, K. (1997) Cell 89, 1175-1184.
18. Gu, W., Shi, X. L. & Roeder, R. G. (1997) Nature (London) 387, 819-823.
19. Lill, N. L., Grossman, S. R., Ginsberg, D., DeCaprio, J. & Livingston, D. M. (1997) Nature (London) 387, 823-827.
20. Grossman, S. R., Perez, M., Kung, A. L., Joseph, M., Mansur, C., Xiao, Z. X., Kumar, S., Howley, P. M. & Livingston, D. M. (1998) Mol. Cell 2, 405-415.
21. Zeng, X., Chen, L., Jost, C. A., Maya, R., Keller, D., Wang, X., Kaelin, W. G., Jr., Oren, M., Chen, J. & Lu, H. (1999) Mol. Cell. Biol. 19, 3257-3266.
22. Momand, J., Zambetti, G. P., Olson, D. C., George, D. & Levine, A. J. (1992) Cell 69, 1237-1245.
23. Yuan, Z. M., Huang, Y., Ishiko, T., Nakada, S., Utsugisawa, T., Shioya, H., Utsugisawa, Y., Yokoyama, K., Weichselbaum, R., Shi, Y., et al. (1999) J. Biol. Chem. 274, 1883-1886.
24. Roth, J., Dobbelstein, M., Freedman, D. A., Shenk, T. & Levine, A. J. (1998) EMBO J. 17, 554-564.
25. Sherr, C. J. (1998) Genes Dev. 12, 2984-2991.
26. Tao, W. & Levine, A. J. (1999) Proc. Natl. Acad. Sci. USA 96, 6937-6941.
27. Weber, J. D., Taylor, L. J., Roussel, M. F., Sherr, C. J. & Bar-Sagi, D. (1999) Nat. Cell Biol. 1, 20-26.
28. Zhang, Y. & Xiong, Y. (1999) Mol. Cell 3, 579-591.
29. Honda, R., Tanaka, H. & Yasuda, H. (1997) FEBS Lett. 420, 25-27.
30. Honda, R. & Yasuda, H. (1999) EMBO J. 18, 22-27.
31. Haupt, Y., Maya, R., Kazaz, A. & Oren, M. (1997) Nature (London) 387, 296-299.
32. Kubbutat, M. H., Jones, S. N. & Vousden, K. H. (1997) Nature (London) 387, 299-303.
33. Zeng, X., Levine, A. J. & Lu, H. (1998) Proc. Natl. Acad. Sci. USA 95, 6681-6686.
34. Pavletich, N. P., Chambers, K. A. & Pabo, C. O. (1993) Genes Dev. 7, 2556-2564.
35. Wu, X., Bayle, J. H., Olson, D. & Levine, A. J. (1993) Genes Dev. 7, 1126-1132.
36. Chen, H., Lin, R. J., Xie, W., Wilpitz, D. & Evans, R. M. (1999) Cell 98, 675-686.
37. Zeng, X., Li, X., Miller, A., Yuan, Z., Yuan, W., Kwok, R. P., Goodman, R. & Lu, H. (2000) Mol. Cell. Biol. 20, 1299-1310.
38. Wadgaonkar, R. & Collins, T. (1999) J. Biol. Chem. 274, 13760-13767.
39. Zeng, X., Keller, D., Lin, W. & Lu, H. (2000) Cancer Res., in press.
40. Lutzker, S. G. & Levine, A. J. (1996) Nat. Med. 2, 804-810.
41. Momand, J., Wu, H. H. & Dasgupta, G. (2000) Gene 242, 15-29.
42. Buschmann, T., Adler, V., Matusevich, E., Fuchs, S. Y. & Ronai, Z. (2000) Cancer Res. 60, 896-900.
43. Zauberman, A., Barak, Y., Ragimov, N., Levy, N. & Oren, M. (1993) EMBO J. 12, 2799-2808.
44. Lu, H. & Levine, A. J. (1995) Proc. Natl. Acad. Sci. USA 92, 5154-5158.
45. Thut, C. J., Chen, J. L., Klemm, R. & Tjian, R. (1995) Science 267, 100-104.
46. Chen, J., Marechal, V. & Levine, A. J. (1993) Mol. Cell. Biol. 13, 4107-4114.
47. Imhof, A., Yang, X. J., Ogryzko, V. V., Nakatani, Y., Wolffe, A. P. & Ge, H. (1997) Curr. Biol. 7, 689-692.
48. Maki, C. G. & Howley, P. M. (1997) Mol. Cell. Biol. 17, 355-363.
49. Lambert, P. F., Kashanchi, F., Radonovich, M. F., Shiekhattar, R. & Brady, J. N. (1998) J. Biol. Chem. 273, 33048-33053.
50. Chehab, N. H., Malikzay, A., Stavridi, E. S. & Halazonetis, T. D. (1999) Proc. Natl. Acad. Sci. USA 96, 13777-13782.
51. Shieh, S. Y., Taya, Y. & Prives, C. (1999) EMBO J. 18, 1815-1823.