Cross-talk between the mitogen activated protein kinase and bone morphogenetic protein/hemojuvelin pathways is required for the induction of hepcidin by holotransferrin in primary mouse hepatocytes

Haematologica

Volumn 94, Issue 6, 2009, Pages 765-772

  Ramey, Guillemette ^a,b   Deschemin, Jean Christophe ^a,b   Vaulont, Sophie ^a,b  

^a INSTITUT COCHIN   (France)

^b INSERM   (France)

Author keywords

BMP HJV; ERK1 2; Hepatocyte; Hepcidin; HFE; Iron; TfR2

Indexed keywords

BONE MORPHOGENETIC PROTEIN; HEMOJUVELIN; HEPCIDIN; HOLOTRANSFERRIN; IRON; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; SMAD1 PROTEIN; SMAD5 PROTEIN; SMAD8 PROTEIN; TRANSFERRIN; TRANSFERRIN RECEPTOR 2; UNCLASSIFIED DRUG; UO 126;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; EX VIVO STUDY; FEMALE; HOMEOSTASIS AND REGULATION; HUMAN; HUMAN CELL; LIVER CELL; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN SYNTHESIS;

ANIMALS; ANTIMICROBIAL CATIONIC PEPTIDES; BLOTTING, NORTHERN; BONE MORPHOGENETIC PROTEINS; CELLS, CULTURED; CULTURE MEDIA, SERUM-FREE; FEMALE; GENE EXPRESSION REGULATION; HEPATOCYTES; HUMANS; MALE; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MICE, INBRED STRAINS; MICE, KNOCKOUT; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASES; RECEPTORS, TRANSFERRIN; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SIGNAL TRANSDUCTION; TIME FACTORS; TRANSFERRIN;

EID: 66749183353     PISSN: 03906078     EISSN: 15928721     Source Type: Journal    
DOI: 10.3324/haematol.2008.003541     Document Type: Article

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