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Volumn 8, Issue 7, 2007, Pages 687-694

T cell development: Better living through chromatin

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; DNA BINDING PROTEIN; DNA NUCLEOTIDYLEXOTRANSFERASE; LYMPHOCYTE ANTIGEN RECEPTOR; NUCLEOPROTEIN; PROTEIN SATB1; T LYMPHOCYTE RECEPTOR; T LYMPHOCYTE RECEPTOR ALPHA CHAIN; T LYMPHOCYTE RECEPTOR BETA CHAIN; TRANSCRIPTION FACTOR RUNX; UNCLASSIFIED DRUG;

EID: 34250738340     PISSN: 15292908     EISSN: 15292916     Source Type: Journal    
DOI: 10.1038/ni1484     Document Type: Review
Times cited : (64)

References (92)
  • 1
    • 0842324785 scopus 로고    scopus 로고
    • The nucleosome: From genomic organization to genomic regulation
    • Khorasanizadeh, S. The nucleosome: From genomic organization to genomic regulation. Cell 116, 259-272 (2004).
    • (2004) Cell , vol.116 , pp. 259-272
    • Khorasanizadeh, S.1
  • 2
    • 15544384745 scopus 로고    scopus 로고
    • ATP-dependent chromatin remodeling
    • Smith, C.L. & Peterson, C.L. ATP-dependent chromatin remodeling. Curr. Top. Dev Biol. 65, 115-148 (2005).
    • (2005) Curr. Top. Dev Biol , vol.65 , pp. 115-148
    • Smith, C.L.1    Peterson, C.L.2
  • 3
    • 22544432870 scopus 로고    scopus 로고
    • The dynamics of chromatin remodeling at promoters
    • Mellor, J. The dynamics of chromatin remodeling at promoters. Mol. Cell 19, 147-157 (2005).
    • (2005) Mol. Cell , vol.19 , pp. 147-157
    • Mellor, J.1
  • 4
    • 33746641324 scopus 로고    scopus 로고
    • Nucleosome displacement in transcription
    • Workman, J.L. Nucleosome displacement in transcription. Genes Dev. 20, 2009-2017 (2006).
    • (2006) Genes Dev , vol.20 , pp. 2009-2017
    • Workman, J.L.1
  • 5
    • 33847070442 scopus 로고    scopus 로고
    • The role of chromatin during transcription
    • Li, B., Carey, J.C. & Workman, J.L. The role of chromatin during transcription. Cell 128, 707-719 (2007).
    • (2007) Cell , vol.128 , pp. 707-719
    • Li, B.1    Carey, J.C.2    Workman, J.L.3
  • 6
    • 0034610814 scopus 로고    scopus 로고
    • The language of covalent histone modifications
    • Strahl, B.D. & Allis, D. The language of covalent histone modifications. Nature 403, 41-45 (2000).
    • (2000) Nature , vol.403 , pp. 41-45
    • Strahl, B.D.1    Allis, D.2
  • 7
    • 0042626332 scopus 로고    scopus 로고
    • Heterochromatin: Stable and unstable invasions at home and abroad
    • Fahrner, J.A. & Baylin, S.B. Heterochromatin: Stable and unstable invasions at home and abroad. Genes Dev. 17, 1805-1812 (2003).
    • (2003) Genes Dev , vol.17 , pp. 1805-1812
    • Fahrner, J.A.1    Baylin, S.B.2
  • 8
    • 27944503593 scopus 로고    scopus 로고
    • Replication of heterochromatin: Insights into mechanisms of epigenetic inheritance
    • Wallace, J.A. & Orr-Weaver, T.L. Replication of heterochromatin: insights into mechanisms of epigenetic inheritance. Chromosoma 114, 389-402 (2005).
    • (2005) Chromosoma , vol.114 , pp. 389-402
    • Wallace, J.A.1    Orr-Weaver, T.L.2
  • 9
    • 33847076248 scopus 로고    scopus 로고
    • Chromatin challenges during DNA replication and repair
    • Groth, A., Rocha, W., Verreault, A. & Almouzni, G. Chromatin challenges during DNA replication and repair. Cell 128, 721-733 (2007).
    • (2007) Cell , vol.128 , pp. 721-733
    • Groth, A.1    Rocha, W.2    Verreault, A.3    Almouzni, G.4
  • 10
    • 33847076849 scopus 로고    scopus 로고
    • Chromatin modifications and their functions
    • Kouzarides, T. Chromatin modifications and their functions. Cell 128, 693-705 (2007).
    • (2007) Cell , vol.128 , pp. 693-705
    • Kouzarides, T.1
  • 11
    • 32444434989 scopus 로고    scopus 로고
    • Histone H4-K16 acetylation controls chromatin structure and protein interactions
    • Shogren-Knaak, M. et al. Histone H4-K16 acetylation controls chromatin structure and protein interactions. Science 311, 844-847 (2006).
    • (2006) Science , vol.311 , pp. 844-847
    • Shogren-Knaak, M.1
  • 12
    • 33746324216 scopus 로고    scopus 로고
    • Chromatin modifications by methylation and ubiquitination: Implications in the regulation of gene expression
    • Shilatifard, A. Chromatin modifications by methylation and ubiquitination: Implications in the regulation of gene expression. Annu. Rev. Biochem. 75, 243-269 (2006).
    • (2006) Annu. Rev. Biochem , vol.75 , pp. 243-269
    • Shilatifard, A.1
  • 13
    • 33751116960 scopus 로고    scopus 로고
    • Histone H3 Lys 4 methylation: Caught in a bind?
    • Sims, R.J., III & Reinberg, D. Histone H3 Lys 4 methylation: Caught in a bind? Genes Dev. 20, 2779-2786 (2006).
    • (2006) Genes Dev , vol.20 , pp. 2779-2786
    • Sims III, R.J.1    Reinberg, D.2
  • 14
    • 33745790132 scopus 로고    scopus 로고
    • Chromatin remodelling: The industrial revolution of DNA around histones
    • Saha, A., Wittmeyer, J. & Cairns, B.R. Chromatin remodelling: The industrial revolution of DNA around histones. Nat. Rev. Mol. Cell Biol. 7, 437-447 (2006).
    • (2006) Nat. Rev. Mol. Cell Biol , vol.7 , pp. 437-447
    • Saha, A.1    Wittmeyer, J.2    Cairns, B.R.3
  • 15
    • 32044439558 scopus 로고    scopus 로고
    • Selective and antagonistic functions of SWI/SNF and Mi-2β nucleosome remodeling complexes during an inflammatory response
    • Ramirez-Carrozzi, V.R. et al. Selective and antagonistic functions of SWI/SNF and Mi-2β nucleosome remodeling complexes during an inflammatory response. Genes Dev. 20, 282-296 (2006).
    • (2006) Genes Dev , vol.20 , pp. 282-296
    • Ramirez-Carrozzi, V.R.1
  • 16
    • 33947638345 scopus 로고    scopus 로고
    • DNA thanslocation and loop formation mechanism of chromatin remodeling by SWI/SNF and RSC
    • Zhang, Y. et al. DNA thanslocation and loop formation mechanism of chromatin remodeling by SWI/SNF and RSC. Mol. Cell 24, 559-568 (2006).
    • (2006) Mol. Cell , vol.24 , pp. 559-568
    • Zhang, Y.1
  • 18
    • 33746856074 scopus 로고    scopus 로고
    • de FACTo nucleosome dynamics
    • Reinberg, D. & Sims, R.J., III. de FACTo nucleosome dynamics. J. Biol. Chem. 281, 23297-23301 (2006).
    • (2006) J. Biol. Chem , vol.281 , pp. 23297-23301
    • Reinberg, D.1    Sims III, R.J.2
  • 19
    • 27644589675 scopus 로고    scopus 로고
    • The diverse functions of histone lysine methylation
    • Martin, C. & Zhang, Y. The diverse functions of histone lysine methylation. Nat. Rev. Mol. Cell Biol. 6, 838-849 (2005).
    • (2005) Nat. Rev. Mol. Cell Biol , vol.6 , pp. 838-849
    • Martin, C.1    Zhang, Y.2
  • 20
    • 2942679507 scopus 로고    scopus 로고
    • Form follows function: The genomic organization of cellular differentiation
    • Kosak, S.T. & Groudine, M. Form follows function: The genomic organization of cellular differentiation. Genes Dev. 18, 1371-1384 (2004).
    • (2004) Genes Dev , vol.18 , pp. 1371-1384
    • Kosak, S.T.1    Groudine, M.2
  • 21
    • 33847077659 scopus 로고    scopus 로고
    • Beyond the sequence: Cellular organization of genome function
    • Misteli, T. Beyond the sequence: Cellular organization of genome function. Cell 128, 787-800 (2007).
    • (2007) Cell , vol.128 , pp. 787-800
    • Misteli, T.1
  • 22
    • 5444243359 scopus 로고    scopus 로고
    • Active genes dynamically colocalize to shared sites of ongoing transcription
    • Osborne, C.S. et al. Active genes dynamically colocalize to shared sites of ongoing transcription. Nat. Genet. 36, 1065-1071 (2004).
    • (2004) Nat. Genet , vol.36 , pp. 1065-1071
    • Osborne, C.S.1
  • 23
    • 33750212321 scopus 로고    scopus 로고
    • Nuclear organization of active and inactive chromatin domains uncovered by chromosome conformation capture-on-chip (4C)
    • Simonis, M. et al. Nuclear organization of active and inactive chromatin domains uncovered by chromosome conformation capture-on-chip (4C). Nat. Genet. 38, 1348-1354 (2006).
    • (2006) Nat. Genet , vol.38 , pp. 1348-1354
    • Simonis, M.1
  • 24
    • 33748289518 scopus 로고    scopus 로고
    • Characterization of the Drosophila melanogaster genome at the nuclear lamina
    • Pickersgill, H. et al. Characterization of the Drosophila melanogaster genome at the nuclear lamina. Nat. Genet. 38 1005-1014 (2006).
    • (2006) Nat. Genet , vol.38 , pp. 1005-1014
    • Pickersgill, H.1
  • 25
    • 26444589253 scopus 로고    scopus 로고
    • The nuclear-envelope protein and transcriptional repressor LAP2β interacts with HDAC3 at the nuclear periphery, and induces histone H4 deacetylation
    • Somech, R. et al. The nuclear-envelope protein and transcriptional repressor LAP2β interacts with HDAC3 at the nuclear periphery, and induces histone H4 deacetylation. J. Cell Sci. 118, 4017-4025 (2005).
    • (2005) J. Cell Sci , vol.118 , pp. 4017-4025
    • Somech, R.1
  • 26
    • 2342501365 scopus 로고    scopus 로고
    • Genome-wide localization of the nuclear transport machinery couples transcriptional status and nuclear organization
    • Casolari, J.M. et al. Genome-wide localization of the nuclear transport machinery couples transcriptional status and nuclear organization. Cell 117, 427-439 (2004).
    • (2004) Cell , vol.117 , pp. 427-439
    • Casolari, J.M.1
  • 27
    • 0037023361 scopus 로고    scopus 로고
    • Subnuclear compartmentalization of immunoglobulin loci during lymphocyte development
    • Kosak, S.T. et al. Subnuclear compartmentalization of immunoglobulin loci during lymphocyte development. Science 296 158-162 (2002).
    • (2002) Science , vol.296 , pp. 158-162
    • Kosak, S.T.1
  • 28
    • 33744779614 scopus 로고    scopus 로고
    • The locus control region is required for association of the murine β-globin locus with engaged transcription factories during erythroid maturation
    • Ragoczy, T., Bender, M.A., Telling, A., Byron, R. & Groudine, M. The locus control region is required for association of the murine β-globin locus with engaged transcription factories during erythroid maturation. Genes Dev. 20, 1447-1457 (2006).
    • (2006) Genes Dev , vol.20 , pp. 1447-1457
    • Ragoczy, T.1    Bender, M.A.2    Telling, A.3    Byron, R.4    Groudine, M.5
  • 29
    • 0036532237 scopus 로고    scopus 로고
    • Gene silencing, cell fate and nuclear organisation
    • Fisher, A.G. & Merkenschlager, M. Gene silencing, cell fate and nuclear organisation. Curr. Opin. Genet. Dev. 12, 193-197 (2002).
    • (2002) Curr. Opin. Genet. Dev , vol.12 , pp. 193-197
    • Fisher, A.G.1    Merkenschlager, M.2
  • 31
    • 0033638506 scopus 로고    scopus 로고
    • Histone acetylation and hSWI/SNF remodeling act in concert to stimulate V(D)J cleavage of nucleosomal DNA
    • Kwon, J., Morshead, K.B., Guyon, J.R., Kingston, R.E. & Oettinger, M.A. Histone acetylation and hSWI/SNF remodeling act in concert to stimulate V(D)J cleavage of nucleosomal DNA. Mol. Cell 6, 1037-1048 (2000).
    • (2000) Mol. Cell , vol.6 , pp. 1037-1048
    • Kwon, J.1    Morshead, K.B.2    Guyon, J.R.3    Kingston, R.E.4    Oettinger, M.A.5
  • 32
    • 4143089242 scopus 로고    scopus 로고
    • ATP-dependent remodeling by SWI/SNF and ISWI proteins stimulates V(D)J cleavage of 5 S arrays
    • Patenge, N., Elkin, S.K. & Oettinger, M.A. ATP-dependent remodeling by SWI/SNF and ISWI proteins stimulates V(D)J cleavage of 5 S arrays. J. Biol. Chem. 279, 35360-35367 (2004).
    • (2004) J. Biol. Chem , vol.279 , pp. 35360-35367
    • Patenge, N.1    Elkin, S.K.2    Oettinger, M.A.3
  • 33
    • 1542377316 scopus 로고    scopus 로고
    • Targeted inhibition of V(D)J recombination by a histone methyl-transferase
    • Osipovich, O. et al. Targeted inhibition of V(D)J recombination by a histone methyl-transferase. Nat. Immunol. 5, 309-316 (2004).
    • (2004) Nat. Immunol , vol.5 , pp. 309-316
    • Osipovich, O.1
  • 34
    • 0034605064 scopus 로고    scopus 로고
    • Chromatin remodeling by the T cell receptor (TCR)-β gene enhancer during early T cell development: Implications for the control of TCR-β locus recombination
    • Mathieu, N., Hempel, W.M., Spicuglia, S., Verthuy, C. & Ferrier, P. Chromatin remodeling by the T cell receptor (TCR)-β gene enhancer during early T cell development: Implications for the control of TCR-β locus recombination. J. Exp. Med. 192, 625-636 (2000).
    • (2000) J. Exp. Med , vol.192 , pp. 625-636
    • Mathieu, N.1    Hempel, W.M.2    Spicuglia, S.3    Verthuy, C.4    Ferrier, P.5
  • 35
    • 33646007633 scopus 로고    scopus 로고
    • Regulation of TCRβ gene assembly by a promoter/enhancer holocomplex
    • Oestreich, K.J. et al. Regulation of TCRβ gene assembly by a promoter/enhancer holocomplex. Immunity 24, 381-391 (2006).
    • (2006) Immunity , vol.24 , pp. 381-391
    • Oestreich, K.J.1
  • 36
    • 0036924095 scopus 로고    scopus 로고
    • Promoter activation by enhancer-dependent and -independent loading of activator and coactivator complexes
    • Spicuglia, S. et al. Promoter activation by enhancer-dependent and -independent loading of activator and coactivator complexes. Mol. Cell 10, 1479-1487 (2002).
    • (2002) Mol. Cell , vol.10 , pp. 1479-1487
    • Spicuglia, S.1
  • 37
    • 0037125979 scopus 로고    scopus 로고
    • Regulation of V(D)J recombination: A dominant role for promoter positioning in gene segment-accessibility
    • Sikes, M.L., Meade, A., Tripathi, R., Krangel, M.S. & Oltz, E.M. Regulation of V(D)J recombination: A dominant role for promoter positioning in gene segment-accessibility. Proc. Natl. Acad. Sci. USA 99, 12309-12314 (2002).
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 12309-12314
    • Sikes, M.L.1    Meade, A.2    Tripathi, R.3    Krangel, M.S.4    Oltz, E.M.5
  • 38
    • 3543011330 scopus 로고    scopus 로고
    • The T-cell receptor β variable gene promoter is required for efficient Vβ rearrangement but not allelic exclusion
    • Ryu, C.J. et al. The T-cell receptor β variable gene promoter is required for efficient Vβ rearrangement but not allelic exclusion. Mol. Cell. Biol. 24, 7015-7023 (2004).
    • (2004) Mol. Cell. Biol , vol.24 , pp. 7015-7023
    • Ryu, C.J.1
  • 39
    • 33645064260 scopus 로고    scopus 로고
    • Turning T-cell receptor β recombination on and off: More questions than answers
    • Jackson, A. & Krangel, M.S. Turning T-cell receptor β recombination on and off: More questions than answers. Immunol. Rev. 209, 129-141 (2006).
    • (2006) Immunol. Rev , vol.209 , pp. 129-141
    • Jackson, A.1    Krangel, M.S.2
  • 40
    • 0035829551 scopus 로고    scopus 로고
    • Asynchronous replication and allelic exclusion in the immune system
    • Mostoslavsky, R. et al. Asynchronous replication and allelic exclusion in the immune system. Nature 414, 221-225 (2001).
    • (2001) Nature , vol.414 , pp. 221-225
    • Mostoslavsky, R.1
  • 41
    • 34248583377 scopus 로고    scopus 로고
    • Reversible contraction by looping of the Tcra and Tcrb loci in rearranging thymocytes
    • Skok, J.A. et al. Reversible contraction by looping of the Tcra and Tcrb loci in rearranging thymocytes. Nat. Immunol. 8, 378-387 (2007).
    • (2007) Nat. Immunol , vol.8 , pp. 378-387
    • Skok, J.A.1
  • 42
    • 34247630198 scopus 로고    scopus 로고
    • Germline transcription from T-cell receptor Vβ gene is uncoupled from allelic exclusion
    • Jia, J., Kondo, M. & Zhuang, Y. Germline transcription from T-cell receptor Vβ gene is uncoupled from allelic exclusion. EMBO J. 26, 2387-2399 (2007).
    • (2007) EMBO J , vol.26 , pp. 2387-2399
    • Jia, J.1    Kondo, M.2    Zhuang, Y.3
  • 43
    • 13444268486 scopus 로고    scopus 로고
    • Regulation of T cell receptor β-allelic exclusion at a level beyond accessibility
    • Jackson, A., Kondilis, H.D., Khor, B., Sleckman, B.P. & Krangel, M.S. Regulation of T cell receptor β-allelic exclusion at a level beyond accessibility. Nat. Immunol. 6, 189-197 (2005).
    • (2005) Nat. Immunol , vol.6 , pp. 189-197
    • Jackson, A.1    Kondilis, H.D.2    Khor, B.3    Sleckman, B.P.4    Krangel, M.S.5
  • 44
    • 1542343974 scopus 로고    scopus 로고
    • Pax5 induces V-to-DJ rearrangements and locus contraction of the immunoglobulin heavy-chain gene
    • Fuxa, M. et al. Pax5 induces V-to-DJ rearrangements and locus contraction of the immunoglobulin heavy-chain gene. Genes Dev. 18, 411-422 (2004).
    • (2004) Genes Dev , vol.18 , pp. 411-422
    • Fuxa, M.1
  • 45
    • 13244275244 scopus 로고    scopus 로고
    • Visualization of looping involving the immunoglobulin heavy-chain locus in developing B cells
    • Sayegh, C., Jhunjhunwala, S., Riblet, R. & Murre, C. Visualization of looping involving the immunoglobulin heavy-chain locus in developing B cells. Genes Dev. 19, 322-327 (2005).
    • (2005) Genes Dev , vol.19 , pp. 322-327
    • Sayegh, C.1    Jhunjhunwala, S.2    Riblet, R.3    Murre, C.4
  • 46
    • 12344270023 scopus 로고    scopus 로고
    • Locus 'decontraction' and centromeric recruitment contribute to allelic exclusion of the immunoglobulin heavy-chain gene
    • Roldan, E. et al. Locus 'decontraction' and centromeric recruitment contribute to allelic exclusion of the immunoglobulin heavy-chain gene. Nat. Immunol. 6, 31-41 (2005).
    • (2005) Nat. Immunol , vol.6 , pp. 31-41
    • Roldan, E.1
  • 47
    • 0038783581 scopus 로고    scopus 로고
    • Increase of TCR Vβ accessibility within Eβ regulatory region influences its recombination frequency but not allelic exclusion
    • Senoo, M. et al. Increase of TCR Vβ accessibility within Eβ regulatory region influences its recombination frequency but not allelic exclusion. J. Immunol. 171, 829-835 (2003).
    • (2003) J. Immunol , vol.171 , pp. 829-835
    • Senoo, M.1
  • 48
    • 26844507374 scopus 로고    scopus 로고
    • Allele-specific regulation of TCRβ variable gene segment chromatin structure
    • Jackson, A. & Krangel, M.S. Allele-specific regulation of TCRβ variable gene segment chromatin structure. J. Immunol. 175, 5186-5191 (2005).
    • (2005) J. Immunol , vol.175 , pp. 5186-5191
    • Jackson, A.1    Krangel, M.S.2
  • 49
    • 0034695501 scopus 로고    scopus 로고
    • A role for histone acetylation in the developmental regulation of V(D)J recombination
    • McMurry, M.T. & Krangel, M.S. A role for histone acetylation in the developmental regulation of V(D)J recombination. Science 287 495-498 (2000).
    • (2000) Science , vol.287 , pp. 495-498
    • McMurry, M.T.1    Krangel, M.S.2
  • 50
    • 23944472244 scopus 로고    scopus 로고
    • Regulation of TCR δ and α repertoires by local and long-distance control of variable gene segment chromatin structure
    • Hawwari, A. & Krangel, M.S. Regulation of TCR δ and α repertoires by local and long-distance control of variable gene segment chromatin structure. J. Exp. Med. 202, 467-472 (2005).
    • (2005) J. Exp. Med , vol.202 , pp. 467-472
    • Hawwari, A.1    Krangel, M.S.2
  • 51
    • 0030273709 scopus 로고    scopus 로고
    • Defect in rearrangement of the most 5′ TCR-Jα following targeted deletion of T early α (TEA): Implications for TCRα locus accessibility
    • Villey, I., Caillol, D., Selz, F., Ferrier, P. & de Villartay, J-P. Defect in rearrangement of the most 5′ TCR-Jα following targeted deletion of T early α (TEA): Implications for TCRα locus accessibility. Immunity 5, 331-342 (1996).
    • (1996) Immunity , vol.5 , pp. 331-342
    • Villey, I.1    Caillol, D.2    Selz, F.3    Ferrier, P.4    de Villartay, J.-P.5
  • 52
    • 18244406271 scopus 로고    scopus 로고
    • α promoters. Nat. Immunol. 6, 481-489 (2005).
    • α promoters. Nat. Immunol. 6, 481-489 (2005).
  • 53
    • 33846475100 scopus 로고    scopus 로고
    • Role for rearranged variable gene segments in directing secondary T cell receptor α recombination
    • Hawwari, A. & Krangel, M.S. Role for rearranged variable gene segments in directing secondary T cell receptor α recombination. Proc. Natl. Acad. Sci. USA 104, 903-907 (2007).
    • (2007) Proc. Natl. Acad. Sci. USA , vol.104 , pp. 903-907
    • Hawwari, A.1    Krangel, M.S.2
  • 54
    • 0041474678 scopus 로고    scopus 로고
    • TEA regulates local TCR-Jα accessibility through histone acetylation
    • Mauvieux, L., Villey, I. & de Villartay, J-P. TEA regulates local TCR-Jα accessibility through histone acetylation. Eur. J. Immunol. 33, 2216-2222 (2003).
    • (2003) Eur. J. Immunol , vol.33 , pp. 2216-2222
    • Mauvieux, L.1    Villey, I.2    de Villartay, J.-P.3
  • 55
    • 33748850103 scopus 로고    scopus 로고
    • Regulation of T cell receptor-α gene recombination by transcription
    • Abarrategui, I. & Krangel, M.S. Regulation of T cell receptor-α gene recombination by transcription. Nat. Immunol. 7, 1109-1115 (2006).
    • (2006) Nat. Immunol , vol.7 , pp. 1109-1115
    • Abarrategui, I.1    Krangel, M.S.2
  • 56
    • 33744462581 scopus 로고    scopus 로고
    • H rearrangement of immunoglobulin genes
    • H rearrangement of immunoglobulin genes. Nat. Immunol. 7, 616-624 (2006).
    • (2006) Nat. Immunol , vol.7 , pp. 616-624
    • Zhang, Z.1
  • 57
    • 23844471918 scopus 로고    scopus 로고
    • A direct interaction between the RAG2 C terminus and the core histones is required for efficient V(D)J recombination
    • West, K.L. et al. A direct interaction between the RAG2 C terminus and the core histones is required for efficient V(D)J recombination. Immunity 23, 203-212 (2005).
    • (2005) Immunity , vol.23 , pp. 203-212
    • West, K.L.1
  • 58
    • 23344453198 scopus 로고    scopus 로고
    • A PHD finger motif in the C terminus of RAG2 modulates recombination activity
    • Elkin, S.K. et al. A PHD finger motif in the C terminus of RAG2 modulates recombination activity. J. Biol. Chem. 280, 28701-28710 (2005).
    • (2005) J. Biol. Chem , vol.280 , pp. 28701-28710
    • Elkin, S.K.1
  • 59
    • 33748511226 scopus 로고    scopus 로고
    • A model for TCR gene segment use
    • Warmflash, A. & Dinner, A.R. A model for TCR gene segment use. J. Immunol. 177, 3857-3864 (2006).
    • (2006) J. Immunol , vol.177 , pp. 3857-3864
    • Warmflash, A.1    Dinner, A.R.2
  • 60
    • 20444391346 scopus 로고    scopus 로고
    • Chromatin in need of a fix: Phosphorylation, of H2AX connects chromatin to DNA repair
    • Thiriet, C. & Hayes, J.J. Chromatin in need of a fix: Phosphorylation, of H2AX connects chromatin to DNA repair. Mol. Cell 18, 617-622 (2005).
    • (2005) Mol. Cell , vol.18 , pp. 617-622
    • Thiriet, C.1    Hayes, J.J.2
  • 61
    • 0034623860 scopus 로고    scopus 로고
    • Response to RAG-mediated VDJ cleavage by NBSI and γ-H2AX
    • Chen, H.T. et al. Response to RAG-mediated VDJ cleavage by NBSI and γ-H2AX. Science 290, 1962-1965 (2000).
    • (2000) Science , vol.290 , pp. 1962-1965
    • Chen, H.T.1
  • 62
    • 3042685445 scopus 로고    scopus 로고
    • Phosphorylation of histone H2B at DNA double-strand breaks
    • Fernandez-Capetillo, O., Allis, C.D. & Nussenzweig, A. Phosphorylation of histone H2B at DNA double-strand breaks. J. Exp. Med. 199 1671-1677 (2004).
    • (2004) J. Exp. Med , vol.199 , pp. 1671-1677
    • Fernandez-Capetillo, O.1    Allis, C.D.2    Nussenzweig, A.3
  • 63
    • 2442688211 scopus 로고    scopus 로고
    • The CD4/CD8 lineage choice: New insights into epigenetic regulation during T cell development
    • Taniuchi, I., Ellmeier, W. & Littman, D.R. The CD4/CD8 lineage choice: new insights into epigenetic regulation during T cell development. Adv. Immunol. 83, 55-89 (2004).
    • (2004) Adv. Immunol , vol.83 , pp. 55-89
    • Taniuchi, I.1    Ellmeier, W.2    Littman, D.R.3
  • 64
    • 0036864610 scopus 로고    scopus 로고
    • Evidence for distinct CD4 silencer functions at different stages of thymocyte differentiation
    • Taniuchi, I., Sunshine, M.J., Festenstein, R. & Littman, D.R. Evidence for distinct CD4 silencer functions at different stages of thymocyte differentiation. Mol. Cell 10, 1083-1096 (2002).
    • (2002) Mol. Cell , vol.10 , pp. 1083-1096
    • Taniuchi, I.1    Sunshine, M.J.2    Festenstein, R.3    Littman, D.R.4
  • 65
    • 0035190986 scopus 로고    scopus 로고
    • Epigenetic silencing of CD4 in T cells committed to the cytotoxic lineage
    • Zou, Y.R. et al. Epigenetic silencing of CD4 in T cells committed to the cytotoxic lineage. Nat. Genet. 29, 332-336 (2001).
    • (2001) Nat. Genet , vol.29 , pp. 332-336
    • Zou, Y.R.1
  • 66
    • 0038610795 scopus 로고    scopus 로고
    • Runx3 and Runx1 are required for CD8 T cell development during thymopoiesis
    • Woolf, E. et al. Runx3 and Runx1 are required for CD8 T cell development during thymopoiesis. Proc. Natl. Acad. Sci. USA 100 7731-7736 (2003).
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 7731-7736
    • Woolf, E.1
  • 67
    • 15244342946 scopus 로고    scopus 로고
    • Dual functions of Runx proteins for reactivating CD8 and silencing CD4 at the commitment process into CD8 thymocytes
    • Sato, T. et al. Dual functions of Runx proteins for reactivating CD8 and silencing CD4 at the commitment process into CD8 thymocytes. Immunity 22, 317-328 (2005).
    • (2005) Immunity , vol.22 , pp. 317-328
    • Sato, T.1
  • 68
    • 18744398397 scopus 로고    scopus 로고
    • Differential requirements for Runx proteins in CD4 repression and epigenetic silencing during T lymphocyte development
    • Taniuchi, I. et al. Differential requirements for Runx proteins in CD4 repression and epigenetic silencing during T lymphocyte development. Cell 111, 621-633 (2002).
    • (2002) Cell , vol.111 , pp. 621-633
    • Taniuchi, I.1
  • 69
    • 1642357581 scopus 로고    scopus 로고
    • Localization of the domains in Runx transcription factors required for the repression of CD4 in thymocytes
    • Telfer, J.C., Hedblom, E.E., Anderson, M.K., Laurent, M.N. & Rothenberg, E.V. Localization of the domains in Runx transcription factors required for the repression of CD4 in thymocytes. J. Immunol. 172, 4359-4370 (2004).
    • (2004) J. Immunol , vol.172 , pp. 4359-4370
    • Telfer, J.C.1    Hedblom, E.E.2    Anderson, M.K.3    Laurent, M.N.4    Rothenberg, E.V.5
  • 70
    • 33748926082 scopus 로고    scopus 로고
    • RUNX1 associates with histone deacetylases and SUV39H1 to repress transcription
    • Reed-Inderbitzin, E. et al. RUNX1 associates with histone deacetylases and SUV39H1 to repress transcription. Oncogene 25 5777-5786 (2006).
    • (2006) Oncogene , vol.25 , pp. 5777-5786
    • Reed-Inderbitzin, E.1
  • 71
    • 28544439524 scopus 로고    scopus 로고
    • Runx1 binds positive transcription elongation factor b and represses transcriptional elongation by RNA polymerase II: Possible mechanism of CD4 silencing
    • Jiang, H., Zhang, F., Kurosu, T. & Peterlin, B.M. Runx1 binds positive transcription elongation factor b and represses transcriptional elongation by RNA polymerase II: Possible mechanism of CD4 silencing. Mol. Cell. Biol. 25, 10675-10683 (2005).
    • (2005) Mol. Cell. Biol , vol.25 , pp. 10675-10683
    • Jiang, H.1    Zhang, F.2    Kurosu, T.3    Peterlin, B.M.4
  • 72
    • 12444333478 scopus 로고    scopus 로고
    • III during thymocyte development
    • III during thymocyte development. J. Immunol. 174, 1513-1524 (2005).
    • (2005) J. Immunol , vol.174 , pp. 1513-1524
    • Feik, N.1
  • 73
    • 33645107299 scopus 로고    scopus 로고
    • Negative regulation of CD8 expression via Cd8 enhancer-mediated recruitment of the zinc finger protein MAZR
    • Bilic, I. et al. Negative regulation of CD8 expression via Cd8 enhancer-mediated recruitment of the zinc finger protein MAZR. Nat. Immunol. 7, 392-400 (2006).
    • (2006) Nat. Immunol , vol.7 , pp. 392-400
    • Bilic, I.1
  • 74
    • 0037062922 scopus 로고    scopus 로고
    • Reciprocal regulation of CD4/CD8 expression by SWI/SNF-like BAF complexes
    • Chi, T.H. et al. Reciprocal regulation of CD4/CD8 expression by SWI/SNF-like BAF complexes. Nature 418, 195-199 (2002).
    • (2002) Nature , vol.418 , pp. 195-199
    • Chi, T.H.1
  • 75
    • 2942520116 scopus 로고    scopus 로고
    • The chromatin remodeler Mi-2β is required for CD4 expression and T cell development
    • Williams, C.J. et al. The chromatin remodeler Mi-2β is required for CD4 expression and T cell development. Immunity 20, 719-733 (2004).
    • (2004) Immunity , vol.20 , pp. 719-733
    • Williams, C.J.1
  • 76
    • 10644289346 scopus 로고    scopus 로고
    • Dynamic repositioning of CD4 and CD8 genes during T cell development
    • Delaire, S., Huang, Y.H., Chan, S.W. & Robey, E.A. Dynamic repositioning of CD4 and CD8 genes during T cell development. J. Exp. Med. 200, 1427-1435 (2004).
    • (2004) J. Exp. Med , vol.200 , pp. 1427-1435
    • Delaire, S.1    Huang, Y.H.2    Chan, S.W.3    Robey, E.A.4
  • 77
    • 10644253554 scopus 로고    scopus 로고
    • Centromeric repositioning of coreceptor loci predicts their stable silencing and the CD4/CD8 lineage choice
    • Merkenschlager, M. et al. Centromeric repositioning of coreceptor loci predicts their stable silencing and the CD4/CD8 lineage choice, J. Exp. Med. 200, 1437-1444 (2004).
    • (2004) J. Exp. Med , vol.200 , pp. 1437-1444
    • Merkenschlager, M.1
  • 78
    • 14244261752 scopus 로고    scopus 로고
    • Assembly of silent chromatin during thymocyte development
    • Su, R.C., Sridharan, R. & Smale, S.T. Assembly of silent chromatin during thymocyte development. Semin. Immunol. 17, 129-140 (2005).
    • (2005) Semin. Immunol , vol.17 , pp. 129-140
    • Su, R.C.1    Sridharan, R.2    Smale, S.T.3
  • 79
    • 2442464995 scopus 로고    scopus 로고
    • Dynamic assembly of silent chromatin during thymocyte maturation
    • Su, R.C. et al. Dynamic assembly of silent chromatin during thymocyte maturation. Nat. Genet. 36, 502-506 (2004).
    • (2004) Nat. Genet , vol.36 , pp. 502-506
    • Su, R.C.1
  • 80
    • 0033083793 scopus 로고    scopus 로고
    • Dynamic repositioning of genes in the nucleus of lymphocytes preparing for cell division
    • Brown, K.E., Baxter, J., Graf, D., Merkenschlager, M. & Fisher, A.G. Dynamic repositioning of genes in the nucleus of lymphocytes preparing for cell division. Mol. Cell 3, 207-217 (1999).
    • (1999) Mol. Cell , vol.3 , pp. 207-217
    • Brown, K.E.1    Baxter, J.2    Graf, D.3    Merkenschlager, M.4    Fisher, A.G.5
  • 81
    • 0036519296 scopus 로고    scopus 로고
    • Haematopoietic cell-fate decisions, chromatin regulation and Ikaros
    • Georgopoulos, K. Haematopoietic cell-fate decisions, chromatin regulation and Ikaros. Nat Rev. Immunol. 2, 162-174 (2002).
    • (2002) Nat Rev. Immunol , vol.2 , pp. 162-174
    • Georgopoulos, K.1
  • 83
    • 0035878121 scopus 로고    scopus 로고
    • + thymocytes by Ikaros proteins in direct competition with an Ets activator
    • + thymocytes by Ikaros proteins in direct competition with an Ets activator. Genes Dev. 15, 1817-1832 (2001).
    • (2001) Genes Dev , vol.15 , pp. 1817-1832
    • Trinh, L.A.1
  • 84
    • 0031437119 scopus 로고    scopus 로고
    • Association of transcriptionally silent genes with Ikaros complexes at centromeric heterochromatin
    • Brown, K.E. et al. Association of transcriptionally silent genes with Ikaros complexes at centromeric heterochromatin. Cell 91 845-854 (1997).
    • (1997) Cell , vol.91 , pp. 845-854
    • Brown, K.E.1
  • 85
    • 0033849663 scopus 로고    scopus 로고
    • Targeting of Ikaros to pericentromeric heterochromatin by direct DNA binding
    • Cobb, B.S. et al. Targeting of Ikaros to pericentromeric heterochromatin by direct DNA binding. Genes Dev. 14, 2146-2160 (2000).
    • (2000) Genes Dev , vol.14 , pp. 2146-2160
    • Cobb, B.S.1
  • 86
    • 0038369968 scopus 로고    scopus 로고
    • Tissue-specific nuclear architecture and gene expression regulated by SATB1
    • Cai, S., Han, H.J. & Kohwi-Shigematsu, T. Tissue-specific nuclear architecture and gene expression regulated by SATB1. Nat. Genet. 34, 42-51 (2003).
    • (2003) Nat. Genet , vol.34 , pp. 42-51
    • Cai, S.1    Han, H.J.2    Kohwi-Shigematsu, T.3
  • 87
    • 0034161939 scopus 로고    scopus 로고
    • The MAR-binding protein SATB1 orchestrates temporal and spatial expression of multiple gene during T-cell development
    • Alvarez, J. et al. The MAR-binding protein SATB1 orchestrates temporal and spatial expression of multiple gene during T-cell development. Genes Dev. 14, 521-535 (2000).
    • (2000) Genes Dev , vol.14 , pp. 521-535
    • Alvarez, J.1
  • 88
    • 0037057668 scopus 로고    scopus 로고
    • SATB1 targets chromatin remodelling to regulate genes over long distances
    • Yasui, D., Miyano, M., Cai, S., Varga-Weisz, P. & Kohwi-Shigematsu, T. SATB1 targets chromatin remodelling to regulate genes over long distances. Nature 419, 641-645 (2002).
    • (2002) Nature , vol.419 , pp. 641-645
    • Yasui, D.1    Miyano, M.2    Cai, S.3    Varga-Weisz, P.4    Kohwi-Shigematsu, T.5
  • 89
    • 33646490450 scopus 로고    scopus 로고
    • Phosphorylation of SATB1, a global gene regulator, acts as a molecular switch regulating its transcriptional activity in vivo
    • Pavan, K.P. et al. Phosphorylation of SATB1, a global gene regulator, acts as a molecular switch regulating its transcriptional activity in vivo. Mol. Cell 22, 231-243 (2006).
    • (2006) Mol. Cell , vol.22 , pp. 231-243
    • Pavan, K.P.1
  • 90
    • 33750465872 scopus 로고    scopus 로고
    • SATB1 packages densely looped, transcriptionally active chromatin for coordinated expression of cytokine genes
    • Cai, S., Lee, C.C. & Kohwi-Shigematsu, T. SATB1 packages densely looped, transcriptionally active chromatin for coordinated expression of cytokine genes. Nat. Genet. 38, 1278-1288 (2006).
    • (2006) Nat. Genet , vol.38 , pp. 1278-1288
    • Cai, S.1    Lee, C.C.2    Kohwi-Shigematsu, T.3
  • 91
    • 21644480480 scopus 로고    scopus 로고
    • Nuclear matrix binding regulates SATB1-mediated transcriptional repression
    • Seo, J., Lozano, M.M. & Dudley, J.P. Nuclear matrix binding regulates SATB1-mediated transcriptional repression. J. Biol. Chem. 280 24600-24609 (2005).
    • (2005) J. Biol. Chem , vol.280 , pp. 24600-24609
    • Seo, J.1    Lozano, M.M.2    Dudley, J.P.3
  • 92
    • 0036886895 scopus 로고    scopus 로고
    • The CD8α gene locus is regulated by the Ikaros family of proteins
    • Harker, N. et al. The CD8α gene locus is regulated by the Ikaros family of proteins. Mol. Cell 10, 1403-1415 (2002).
    • (2002) Mol. Cell , vol.10 , pp. 1403-1415
    • Harker, N.1


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