The p53QS transactivation-deficient mutant shows stress-specific apoptotic activity and induces embryonic lethality

Nature Genetics

Volumn 37, Issue 2, 2005, Pages 145-152

  Johnson, Thomas M ^a   Hammond, Ester M ^a   Giaccia, Amato ^a   Attardi, Laura D ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MUTANT PROTEIN; PROTEIN BAX; PROTEIN MDM2; PROTEIN P53; TRANSACTIVATOR PROTEIN; BAX PROTEIN, MOUSE; MDM2 PROTEIN, MOUSE; NUCLEAR PROTEIN; ONCOPROTEIN; PROTEIN BCL 2;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CELL CYCLE ARREST; CELL CYCLE G1 PHASE; CONTROLLED STUDY; DNA DAMAGE; EMBRYO; GENE MUTATION; GENETIC TRANSCRIPTION; HYPOXIA; LETHALITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEFECT; PROTEIN FUNCTION; STRESS; TRANSACTIVATION; ANIMAL; CELL CYCLE; GENE EXPRESSION REGULATION; GENETIC TRANSFECTION; GENETICS; MUTATION; TRANSGENIC MOUSE; TUMOR SUPPRESSOR GENE;

ANIMALIA;

ANIMALS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CELL CYCLE; DNA DAMAGE; EMBRYO; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, P53; MICE; MICE, TRANSGENIC; MUTATION; NUCLEAR PROTEINS; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; PROTO-ONCOGENE PROTEINS C-MDM2; TRANS-ACTIVATION (GENETICS); TRANS-ACTIVATORS; TRANSFECTION;

EID: 13944278507     PISSN: 10614036     EISSN: 15461718     Source Type: Journal    
DOI: 10.1038/ng1498     Document Type: Article

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