-
3
-
-
14244272868
-
-
Adams, P. D., Grosse-Kunstleve, R. W., Hung, L.-W., Ioerger, T. R., McCoy, A. J., Moriarty, N. W., Read, R. J., Sacchettini, J. C, Sauter, N. K. & Terwilliger, T. C. (2002). Acta Cryst. D58, 1948-1954.
-
(2002)
Acta Cryst
, vol.D58
, pp. 1948-1954
-
-
Adams, P.D.1
Grosse-Kunstleve, R.W.2
Hung, L.-W.3
Ioerger, T.R.4
McCoy, A.J.5
Moriarty, N.W.6
Read, R.J.7
Sacchettini, J.C.8
Sauter, N.K.9
Terwilliger, T.C.10
-
4
-
-
33745644458
-
-
Alterio, V, Vitale, R. M., Monti, S. M., Pedone, C, Scozzafava, A., Cecchi, A., De Simone, G. & Supuran, C. T. (2006). J Am. Chem Soc. 128, 8329-8335.
-
(2006)
J Am. Chem Soc
, vol.128
, pp. 8329-8335
-
-
Alterio, V.1
Vitale, R.M.2
Monti, S.M.3
Pedone, C.4
Scozzafava, A.5
Cecchi, A.6
De Simone, G.7
Supuran, C.T.8
-
5
-
-
0036646055
-
-
Anand, K., Palm, G J., Mesters, J. R., Siddell, S. G, Ziebuhr, J. & Hilgenfeld, R. (2002). EMBO J. 21, 3213-3224.
-
(2002)
EMBO J
, vol.21
, pp. 3213-3224
-
-
Anand, K.1
Palm, G.J.2
Mesters, J.R.3
Siddell, S.G.4
Ziebuhr, J.5
Hilgenfeld, R.6
-
6
-
-
33846036096
-
-
Berman, H., Henrick, K., Nakamura, H. & Markley, J. L. (2007). Nucleic Acids Res. 35, D301-D303.
-
(2007)
Nucleic Acids Res
, vol.35
-
-
Berman, H.1
Henrick, K.2
Nakamura, H.3
Markley, J.L.4
-
7
-
-
0024279636
-
-
Betzel, G, Dauter, Z., Dauter, M., Ingelman, M., Papendorf, G, Wilson, K. S. & Branner, S. (1988). J Mol. Biol. 204, 803-804.
-
(1988)
J Mol. Biol
, vol.204
, pp. 803-804
-
-
Betzel, G.1
Dauter, Z.2
Dauter, M.3
Ingelman, M.4
Papendorf, G.5
Wilson, K.S.6
Branner, S.7
-
8
-
-
24944493938
-
-
Bradley, P, Misura, K. M. & Baker, D. (2005). Science, 309, 1868- 1871.
-
(2005)
Science
, vol.309
, pp. 1868-1871
-
-
Bradley, P.1
Misura, K.M.2
Baker, D.3
-
9
-
-
34249084272
-
-
Burla, M. C, Caliandro, R., Camalli, M., Carrozzini, B., Cascarano, G L., De Caro, L., Giacovazzo, C, Polidori, G, Siliqi, D. & Spagna, R. (2007).J. Appl. Cryst. 40, 609-613.
-
(2007)
J. Appl. Cryst
, vol.40
, pp. 609-613
-
-
Burla, M.C.1
Caliandro, R.2
Camalli, M.3
Carrozzini, B.4
Cascarano, G.L.5
De Caro, L.6
Giacovazzo, C.7
Polidori, G.8
Siliqi, D.9
Spagna, R.10
-
10
-
-
33645156425
-
-
Caliandro, R., Carrozzini, B., Cascarano, G L., De Caro, L., Giacovazzo, C, Mazzone, A. M. & Siliqi, D (2006).J. Appl. Cryst. 39, 185-193.
-
(2006)
J. Appl. Cryst
, vol.39
, pp. 185-193
-
-
Caliandro, R.1
Carrozzini, B.2
Cascarano, G.L.3
De Caro, L.4
Giacovazzo, C.5
Mazzone, A.M.6
Siliqi, D.7
-
11
-
-
43749100235
-
-
Caliandro, R., Carrozzini, B., Cascarano, G L., De Caro, L., Giacovazzo, C, Mazzone, A. & Siliqi, D (2008).J. Appl. Cryst. 41, 548-553.
-
(2008)
J. Appl. Cryst
, vol.41
, pp. 548-553
-
-
Caliandro, R.1
Carrozzini, B.2
Cascarano, G.L.3
De Caro, L.4
Giacovazzo, C.5
Mazzone, A.6
Siliqi, D.7
-
12
-
-
49749104894
-
-
Caliandro, R., Carrozzini, B., Cascarano, G L., De Caro, L., Giacovazzo, C. & Siliqi, D (2008). Acta Cryst. A64, 519-528.
-
(2008)
Acta Cryst
, vol.A64
, pp. 519-528
-
-
Caliandro, R.1
Carrozzini, B.2
Cascarano, G.L.3
De Caro, L.4
Giacovazzo, C.5
Siliqi, D.6
-
13
-
-
61349162237
-
-
Caliandro, R., Carrozzini, B., Cascarano, G L., Giacovazzo, C, Mazzone, A. M. & Siliqi, D (2009). Acta Cryst. D65, 249-256.
-
(2009)
Acta Cryst
, vol.D65
, pp. 249-256
-
-
Caliandro, R.1
Carrozzini, B.2
Cascarano, G.L.3
Giacovazzo, C.4
Mazzone, A.M.5
Siliqi, D.6
-
15
-
-
0033198415
-
-
Cowtan, K. (1999). Acta Cryst. D55, 1555-1567.
-
(1999)
Acta Cryst
, vol.D55
, pp. 1555-1567
-
-
Cowtan, K.1
-
16
-
-
33748337934
-
-
Cowtan, K. (2006). Acta Cryst., D62, 1002-1011.
-
(2006)
Acta Cryst
, vol.D62
, pp. 1002-1011
-
-
Cowtan, K.1
-
17
-
-
0030046275
-
-
Dobbs, A. J., Anderson, B. E, Faber, H. R. & Baker, E. N. (1996). Acta Cryst. D52, 356-368.
-
(1996)
Acta Cryst
, vol.D52
, pp. 356-368
-
-
Dobbs, A.J.1
Anderson, B.E.2
Faber, H.R.3
Baker, E.N.4
-
22
-
-
0032077985
-
-
Greenblatt, H. M., Feinberg, H., Tucker, P. A. & Shoham, G (1998). Acta Cryst. D54, 289-305.
-
(1998)
Acta Cryst
, vol.D54
, pp. 289-305
-
-
Greenblatt, H.M.1
Feinberg, H.2
Tucker, P.A.3
Shoham, G.4
-
23
-
-
34250862763
-
-
He, Y., Yao, D.-Q., Gu, Y.-J., Lin, Z.-J, Zheng, C.-D. & Fan, H.-F (2007). Acta Cryst. D63, 793-799.
-
(2007)
Acta Cryst
, vol.D63
, pp. 793-799
-
-
He, Y.1
Yao, D.-Q.2
Gu, Y.-J.3
Lin, Z.-J.4
Zheng, C.-D.5
Fan, H.-F.6
-
24
-
-
30044444914
-
-
Horvath, A. J., Irving, J. A., Rossjohn, J., Law, R. H., Bottomley, S. P, Quinsey, N. S., Pike, R. N., Coughlin, P. B. & Whisstock, J. C. (2005). J. Biol. Chem. 280, 43168-43178.
-
(2005)
J. Biol. Chem
, vol.280
, pp. 43168-43178
-
-
Horvath, A.J.1
Irving, J.A.2
Rossjohn, J.3
Law, R.H.4
Bottomley, S.P.5
Quinsey, N.S.6
Pike, R.N.7
Coughlin, P.B.8
Whisstock, J.C.9
-
25
-
-
0037321470
-
-
Jamrog, D C, Zhang, Y & Phillips, G N. (2003). Acta Cryst. D59, 304-314.
-
(2003)
Acta Cryst
, vol.D59
, pp. 304-314
-
-
Jamrog, D.C.1
Zhang, Y.2
Phillips, G.N.3
-
27
-
-
0033081529
-
-
Kissinger, C. R., Gehlhaar, D K. & Fogel, D B. (1999). Acta Cryst. D55, 484-491.
-
(1999)
Acta Cryst
, vol.D55
, pp. 484-491
-
-
Kissinger, C.R.1
Gehlhaar, D.K.2
Fogel, D.B.3
-
28
-
-
15744363736
-
-
Kolberg, M., Logan, D T., Bleifuss, G, Potsch, S., Sjoberg, B. M., Graslund, A., Lubitz, W, Lassmann, G & Lendzian, F (2005). J Biol. Chem. 280, 11233-11246.
-
(2005)
J Biol. Chem
, vol.280
, pp. 11233-11246
-
-
Kolberg, M.1
Logan, D.T.2
Bleifuss, G.3
Potsch, S.4
Sjoberg, B.M.5
Graslund, A.6
Lubitz, W.7
Lassmann, G.8
Lendzian, F.9
-
29
-
-
1842577654
-
-
Kortemme, T., Joachimiak, L. A., Bullock, A. N., Schuler, A. D, Stoddard, B. L. & Baker, D (2004). Nature Struct. Mol. Biol. 11, 371-379.
-
(2004)
Nature Struct. Mol. Biol
, vol.11
, pp. 371-379
-
-
Kortemme, T.1
Joachimiak, L.A.2
Bullock, A.N.3
Schuler, A.D.4
Stoddard, B.L.5
Baker, D.6
-
30
-
-
0034929414
-
-
Levitt, D G (2001). Acta Cryst. D57, 1013-1019.
-
(2001)
Acta Cryst
, vol.D57
, pp. 1013-1019
-
-
Levitt, D.G.1
-
31
-
-
34447508216
-
-
McCoy, A. J., Grosse-Kunstleve, R. W., Adams, P. D, Winn, M. D, Storoni, L. C. & Read, R. J. (2007).J. Appl. Cryst. 40, 658-674.
-
(2007)
J. Appl. Cryst
, vol.40
, pp. 658-674
-
-
McCoy, A.J.1
Grosse-Kunstleve, R.W.2
Adams, P.D.3
Winn, M.D.4
Storoni, L.C.5
Read, R.J.6
-
32
-
-
84920325457
-
-
Navaza, J. (1994). Acta Cryst. A50, 157-163.
-
(1994)
Acta Cryst
, vol.A50
, pp. 157-163
-
-
Navaza, J.1
-
33
-
-
0032964481
-
-
Perrakis, A., Morris, R. & Lamzin, V. S. (1999). Nature Struct. Biol. 6, 458-463.
-
(1999)
Nature Struct. Biol
, vol.6
, pp. 458-463
-
-
Perrakis, A.1
Morris, R.2
Lamzin, V.S.3
-
34
-
-
36049029967
-
-
Qian, B., Raman, S., Das, R., Bradley, P., McCoy, A. J., Read, R. J. & Baker, D. (2007). Nature (London), 450, 259-264.
-
(2007)
Nature (London)
, vol.450
, pp. 259-264
-
-
Qian, B.1
Raman, S.2
Das, R.3
Bradley, P.4
McCoy, A.J.5
Read, R.J.6
Baker, D.7
-
35
-
-
0035788107
-
-
Read, R. J. (2001). Acta Cryst. D57, 1373-1382.
-
(2001)
Acta Cryst
, vol.D57
, pp. 1373-1382
-
-
Read, R.J.1
-
37
-
-
56649117573
-
-
Rigden, D. J., Keegan, R. M. & Wimi, M. D. (2008). Acta Cryst. D64, 1288-1291.
-
(2008)
Acta Cryst
, vol.D64
, pp. 1288-1291
-
-
Rigden, D.J.1
Keegan, R.M.2
Wimi, M.D.3
-
39
-
-
16644367949
-
-
Schwarzenbacher, R., Godzik, A., Grzechnik, S. K. & Jaroszewski, L. (2004). Acta Cryst. D60, 1229-1236.
-
(2004)
Acta Cryst
, vol.D60
, pp. 1229-1236
-
-
Schwarzenbacher, R.1
Godzik, A.2
Grzechnik, S.K.3
Jaroszewski, L.4
-
41
-
-
0002095439
-
-
Sheriff, S., Klei, H. E. & Davis, M. E. (1999). J Appl. Cryst. 32, 98-101.
-
(1999)
J Appl. Cryst
, vol.32
, pp. 98-101
-
-
Sheriff, S.1
Klei, H.E.2
Davis, M.E.3
-
42
-
-
0032530578
-
-
Shortle, D, Simons, K. T. & Baker, D (1998). Proc. Natl Acad. Sci USA, 95, 11158-11162.
-
(1998)
Proc. Natl Acad. Sci USA
, vol.95
, pp. 11158-11162
-
-
Shortle, D.1
Simons, K.T.2
Baker, D.3
-
43
-
-
0031585984
-
-
Simons, K. T., Kooperberg, G, Huang, E. & Baker, D (1997).J. Mol Biol. 268, 209-225.
-
(1997)
J. Mol Biol
, vol.268
, pp. 209-225
-
-
Simons, K.T.1
Kooperberg, G.2
Huang, E.3
Baker, D.4
-
44
-
-
0032929780
-
-
Simons, K. T., Ruczinski, I., Kooperberg, C, Fox, B. A., Bystroff, C. & Baker, D (1999). Proteins, 34, 82-95.
-
(1999)
Proteins
, vol.34
, pp. 82-95
-
-
Simons, K.T.1
Ruczinski, I.2
Kooperberg, C.3
Fox, B.A.4
Bystroff, C.5
Baker, D.6
-
48
-
-
37349103121
-
-
Terwilliger, T C, Grosse-Kunstleve, R. W., Afonine, P. V., Moriarty, N. W., Zwart, P. H, Hung, L.-W., Read, R. J. & Adams, P. D (2008). Acta Cryst. D64, 61-69.
-
(2008)
Acta Cryst
, vol.D64
, pp. 61-69
-
-
Terwilliger, T.C.1
Grosse-Kunstleve, R.W.2
Afonine, P.V.3
Moriarty, N.W.4
Zwart, P.H.5
Hung, L.-W.6
Read, R.J.7
Adams, P.D.8
-
49
-
-
65349117310
-
-
PhD thesis. Technische Universitat München, Germany
-
Turk, D (1992). PhD thesis. Technische Universitat München, Germany.
-
(1992)
-
-
Turk, D.1
-
50
-
-
0035895429
-
-
Uhrinova, S., Uhrin, D, Nairn, J., Price, N. C, Fothergill-Gilmore, L. A. & Barlow, P. N. (2001).J. Mol. Biol. 306, 275-290.
-
(2001)
J. Mol. Biol
, vol.306
, pp. 275-290
-
-
Uhrinova, S.1
Uhrin, D.2
Nairn, J.3
Price, N.C.4
Fothergill-Gilmore, L.A.5
Barlow, P.N.6
-
53
-
-
84943120540
-
-
Yao, J.-X. (1981). Acta Cryst. A37, 642-644.
-
(1981)
Acta Cryst
, vol.A37
, pp. 642-644
-
-
Yao, J.-X.1
-
54
-
-
0036849993
-
-
Yao, J.-X. (2002). Acta Cryst. D58, 1941-1947.
-
(2002)
Acta Cryst
, vol.D58
, pp. 1941-1947
-
-
Yao, J.-X.1
-
55
-
-
0345989988
-
-
edited by E. Arnold & M. G Rossmann, pp, Dordrecht: Kluwer Academic Publishers
-
Zhang, K. Y J., Cowtan, K. D & Main, P. (2001). International Tables for Crystallography, Vol. F, edited by E. Arnold & M. G Rossmann, pp. 311-331. Dordrecht: Kluwer Academic Publishers.
-
(2001)
International Tables for Crystallography
, vol.F
, pp. 311-331
-
-
Zhang, K.Y.J.1
Cowtan, K.D.2
Main, P.3
-
56
-
-
65349108955
-
-
Institute of Physics, Chinese Academy of Sciences, Beijing, People's Republic of China
-
Zhang, T, He, Y, Gu, Y.-X., Zheng, C.-D, Hao, Q., Wang, J.-W. & Fan, H.-E (2007). OAS1S06: A Direct-Method Program for SAD/ SIR Phasing and Reciprocal-Space Fragment Extension. Institute of Physics, Chinese Academy of Sciences, Beijing, People's Republic of China.
-
(2007)
OAS1S06: A Direct-Method Program for SAD/ SIR Phasing and Reciprocal-Space Fragment Extension
-
-
Zhang, T.1
He, Y.2
Gu, Y.-X.3
Zheng, C.-D.4
Hao, Q.5
Wang, J.-W.6
Fan, H.-E.7
-
57
-
-
0030044141
-
-
von Itzstein, M.; Dyason, J. C; Oliver, S. W.; White, H. F.; Wu, W. Y.; Kok, G. B.; Pegg, M. S. A study of the active site of influenza virus sialidase: an approach to the rational design of novel anti-influenza drugs. J. Med. Chem. 1996, 39, 388-391.
-
von Itzstein, M.; Dyason, J. C; Oliver, S. W.; White, H. F.; Wu, W. Y.; Kok, G. B.; Pegg, M. S. A study of the active site of influenza virus sialidase: an approach to the rational design of novel anti-influenza drugs. J. Med. Chem. 1996, 39, 388-391.
-
-
-
-
58
-
-
0028925854
-
-
White, C. L.; Janakiraman, M. N.; Laver, W. G.; Philippon, C; Vasella, A.; Air, G. M.; Luo, M. A sialic acid-derived phosphonate analog inhibits different strains of influenza virus neuraminidase with different efficiencies. J. Mol. Biol. 1995 245, 623-634.
-
White, C. L.; Janakiraman, M. N.; Laver, W. G.; Philippon, C; Vasella, A.; Air, G. M.; Luo, M. A sialic acid-derived phosphonate analog inhibits different strains of influenza virus neuraminidase with different efficiencies. J. Mol. Biol. 1995 245, 623-634.
-
-
-
-
59
-
-
0028925854
-
-
White, C. L.; Janakiraman, M. N.; Laver, W. G.; Philippon, C; Vasella, A.; Air, G. M.; Luo, M. A sialic acid-derived phosphonate analog inhibits different strains of influenza virus neuraminidase with different efficiencies. J. Mol. Biol. 1995 245, 623-634.
-
White, C. L.; Janakiraman, M. N.; Laver, W. G.; Philippon, C; Vasella, A.; Air, G. M.; Luo, M. A sialic acid-derived phosphonate analog inhibits different strains of influenza virus neuraminidase with different efficiencies. J. Mol. Biol. 1995 245, 623-634.
-
-
-
-
60
-
-
0028325249
-
Molecular Modeling Studies on Ligand Binding to Sialidase from Influenza Virus and the Mechanism of Catalysis
-
Taylor, N. R.; von Itzstein, M. Molecular Modeling Studies on Ligand Binding to Sialidase from Influenza Virus and the Mechanism of Catalysis. J. Med. Chem. 1994, 37, 616-624.
-
(1994)
J. Med. Chem
, vol.37
, pp. 616-624
-
-
Taylor, N.R.1
von Itzstein, M.2
-
61
-
-
65349089782
-
-
Stoll, V, Stewart, K. D, Marmg, C. J, Muchmore, S, Giranda, V, Gu, Y. G, Wang, G, Chen, Y, Sun, M, Zhao, C; Kennedy, A. L, Madigan, D. L.;
-
Stoll, V.; Stewart, K. D.; Marmg, C. J.; Muchmore, S.; Giranda, V.; Gu, Y. G.; Wang, G.; Chen, Y.; Sun, M.; Zhao, C; Kennedy, A. L.; Madigan, D. L.;
-
-
-
-
62
-
-
0037469141
-
Influenza neuraminidase inhibitors: Structure-based design of a novel inhibitor series
-
Xu, Y.; Saldivar, A.; Kati, W.; Laver, G.; Sowin, T.; Sham, H. L.; Greer, J.; Kempf, D. Influenza neuraminidase inhibitors: structure-based design of a novel inhibitor series. Biochemistry 2003, 42, 718-727.
-
(2003)
Biochemistry
, vol.42
, pp. 718-727
-
-
Xu, Y.1
Saldivar, A.2
Kati, W.3
Laver, G.4
Sowin, T.5
Sham, H.L.6
Greer, J.7
Kempf, D.8
-
63
-
-
0028940702
-
Structures of aromatic inhibitors of influenza virus neuraminidase
-
Jedrzejas, M. J.; Singh, S.; Brouillette, W. J.; Laver, W. G.; Air, G. M.; Luo, M. Structures of aromatic inhibitors of influenza virus neuraminidase. Biochemistry 1995, 34, 3144-3151.
-
(1995)
Biochemistry
, vol.34
, pp. 3144-3151
-
-
Jedrzejas, M.J.1
Singh, S.2
Brouillette, W.J.3
Laver, W.G.4
Air, G.M.5
Luo, M.6
-
64
-
-
0028940702
-
Structures of aromatic inhibitors of influenza virus neuraminidase
-
Jedrzejas, M. J.; Singh, S.; Brouillette, W. J.; Laver, W. G.; Air, G. M.; Luo, M. Structures of aromatic inhibitors of influenza virus neuraminidase. Biochemistry 1995, 34, 3144-3151.
-
(1995)
Biochemistry
, vol.34
, pp. 3144-3151
-
-
Jedrzejas, M.J.1
Singh, S.2
Brouillette, W.J.3
Laver, W.G.4
Air, G.M.5
Luo, M.6
-
65
-
-
0028940702
-
Structures of aromatic inhibitors of influenza virus neuraminidase
-
Jedrzejas, M. J.; Singh, S.; Brouillette, W. J.; Laver, W. G.; Air, G. M.; Luo, M. Structures of aromatic inhibitors of influenza virus neuraminidase. Biochemistry 1995, 34, 3144-3151.
-
(1995)
Biochemistry
, vol.34
, pp. 3144-3151
-
-
Jedrzejas, M.J.1
Singh, S.2
Brouillette, W.J.3
Laver, W.G.4
Air, G.M.5
Luo, M.6
-
66
-
-
0029099621
-
Structure-based inhibitors of influenza virus sialidase. A benzoic acid lead with novel interaction
-
Singh, S.; Jedrzejas, M. J.; Air, G. M.; Luo, M.; Laver, W. G.; Brouillette, W. J. Structure-based inhibitors of influenza virus sialidase. A benzoic acid lead with novel interaction. J. Med. Chem. 1995 58,3217-3225.
-
(1995)
J. Med. Chem
, vol.58
, pp. 3217-3225
-
-
Singh, S.1
Jedrzejas, M.J.2
Air, G.M.3
Luo, M.4
Laver, W.G.5
Brouillette, W.J.6
-
67
-
-
0032526697
-
Drug design against a shifting target: A structural basis for resistance to inhibitors in a variant of influenza virus neuraminidase
-
Varghese, J. N.; Smith, P. W.; Solhs, S. L.; Bhck, T. J.; Sahasrabudhe, A.; McKimm-Breschkm, J. L.; Colman, P. M. Drug design against a shifting target: a structural basis for resistance to inhibitors in a variant of influenza virus neuraminidase. Structure 1998, 6, 735-746.
-
(1998)
Structure
, vol.6
, pp. 735-746
-
-
Varghese, J.N.1
Smith, P.W.2
Solhs, S.L.3
Bhck, T.J.4
Sahasrabudhe, A.5
McKimm-Breschkm, J.L.6
Colman, P.M.7
-
68
-
-
0032526697
-
Drug design against a shifting target: A structural basis for resistance to inhibitors in a variant of influenza virus neuraminidase
-
Varghese, J. N.; Smith, P. W.; Solhs, S. L.; Bhck, T. J.; Sahasrabudhe, A.; McKimm-Breschkm, J. L.; Colman, P. M. Drug design against a shifting target: a structural basis for resistance to inhibitors in a variant of influenza virus neuraminidase. Structure 1998, 6, 735-746.
-
(1998)
Structure
, vol.6
, pp. 735-746
-
-
Varghese, J.N.1
Smith, P.W.2
Solhs, S.L.3
Bhck, T.J.4
Sahasrabudhe, A.5
McKimm-Breschkm, J.L.6
Colman, P.M.7
-
69
-
-
0028925854
-
-
White, C. L.; Janakiraman, M. N.; Laver, W. G.; Philippon, C; Vasella, A.; Air, G. M.; Luo, M. A sialic acid-derived phosphonate analog inhibits different strains of influenza virus neuraminidase with different efficiencies. J. Mol. Biol. 1995 245, 623-634.
-
White, C. L.; Janakiraman, M. N.; Laver, W. G.; Philippon, C; Vasella, A.; Air, G. M.; Luo, M. A sialic acid-derived phosphonate analog inhibits different strains of influenza virus neuraminidase with different efficiencies. J. Mol. Biol. 1995 245, 623-634.
-
-
-
-
70
-
-
33645458687
-
Unsaturated N-acetyl- D-glucosaminuronic acid glycosides as inhibitors of influenza virus sialidase
-
Mann, M. C; Islam, T.; Dyason, J. C; Florio, P.; Trower, C. J.; Thomson, R. J.; von Itzstein, M. Unsaturated N-acetyl- D-glucosaminuronic acid glycosides as inhibitors of influenza virus sialidase. Glycoconj. J. 2006 23, 127-133.
-
(2006)
Glycoconj. J
, vol.23
, pp. 127-133
-
-
Mann, M.C.1
Islam, T.2
Dyason, J.C.3
Florio, P.4
Trower, C.J.5
Thomson, R.J.6
von Itzstein, M.7
-
71
-
-
0031911783
-
Mutations in a conserved residue in the influenza virus neuraminidase active site decreases sensitivity to Neu5Ac2en-derived inhibitors
-
McKimm-Breschkm, J.L.; Sahasrabudhe, A.; Bhck, T.J.; McDonald, M.; Colman, P. M.; Hart, G. J.; Bethell, R. C; Varghese, J. N. Mutations in a conserved residue in the influenza virus neuraminidase active site decreases sensitivity to Neu5Ac2en-derived inhibitors. J. Vir. 1998, 72, 2456-2462.
-
(1998)
J. Vir
, vol.72
, pp. 2456-2462
-
-
McKimm-Breschkm, J.L.1
Sahasrabudhe, A.2
Bhck, T.J.3
McDonald, M.4
Colman, P.M.5
Hart, G.J.6
Bethell, R.C.7
Varghese, J.N.8
-
72
-
-
0031911783
-
Mutations in a conserved residue in the influenza virus neuraminidase active site decreases sensitivity to Neu5Ac2en-derived inhibitors
-
McKimm-Breschkm, J.L.; Sahasrabudhe, A.; Bhck, T.J.; McDonald, M.; Colman, P. M.; Hart, G. J.; Bethell, R. C; Varghese, J. N. Mutations in a conserved residue in the influenza virus neuraminidase active site decreases sensitivity to Neu5Ac2en-derived inhibitors. J. Vir. 1998, 72, 2456-2462.
-
(1998)
J. Vir
, vol.72
, pp. 2456-2462
-
-
McKimm-Breschkm, J.L.1
Sahasrabudhe, A.2
Bhck, T.J.3
McDonald, M.4
Colman, P.M.5
Hart, G.J.6
Bethell, R.C.7
Varghese, J.N.8
-
73
-
-
0031911783
-
Mutations in a conserved residue in the influenza virus neuraminidase active site decreases sensitivity to Neu5Ac2en-derived inhibitors
-
McKimm-Breschkm, J.L.; Sahasrabudhe, A.; Bhck, T.J.; McDonald, M.; Colman, P. M.; Hart, G. J.; Bethell, R. C; Varghese, J. N. Mutations in a conserved residue in the influenza virus neuraminidase active site decreases sensitivity to Neu5Ac2en-derived inhibitors. J. Vir. 1998, 72, 2456-2462.
-
(1998)
J. Vir
, vol.72
, pp. 2456-2462
-
-
McKimm-Breschkm, J.L.1
Sahasrabudhe, A.2
Bhck, T.J.3
McDonald, M.4
Colman, P.M.5
Hart, G.J.6
Bethell, R.C.7
Varghese, J.N.8
-
74
-
-
0035083950
-
Analysis of inhibitor binding in influenza virus neuraminidase
-
Smith, B. J.; Colman, P. M.; von Itzstein, M.; Danylec, B.; Varghese, J. N. Analysis of inhibitor binding in influenza virus neuraminidase. Protein. Sci. 2001, 10, 689-696.
-
(2001)
Protein. Sci
, vol.10
, pp. 689-696
-
-
Smith, B.J.1
Colman, P.M.2
von Itzstein, M.3
Danylec, B.4
Varghese, J.N.5
-
75
-
-
0030591866
-
Novel inhibitors of influenza sialidases related to GG167 structure-activity, crystallographic and Molecular dynamics studies with 4H-pyran-2-carboxylic acid 6-carboxamides
-
Smith, P. W.; Solhs, S. L.; Howes, P. D; Cherry, P. C; Cobley, K. N.; Taylor, H.; Whittmgton, A. R.; Scicinski, J.; Bethell, R. C; Taylor, N.; Skarzynski, T.; Cleasby, A.; Singh, O.; Wonacott, A.; Varghese, J.; Colman, P. Novel inhibitors of influenza sialidases related to GG167 structure-activity, crystallographic and Molecular dynamics studies with 4H-pyran-2-carboxylic acid 6-carboxamides. Bioorg.Med. Chem. Lett. 1996, 6, 2931-2936.
-
(1996)
Bioorg.Med. Chem. Lett
, vol.6
, pp. 2931-2936
-
-
Smith, P.W.1
Solhs, S.L.2
Howes, P.D.3
Cherry, P.C.4
Cobley, K.N.5
Taylor, H.6
Whittmgton, A.R.7
Scicinski, J.8
Bethell, R.C.9
Taylor, N.10
Skarzynski, T.11
Cleasby, A.12
Singh, O.13
Wonacott, A.14
Varghese, J.15
Colman, P.16
-
76
-
-
0031911783
-
Mutations in a conserved residue in the influenza virus neuraminidase active site decreases sensitivity to Neu5Ac2en-derived inhibitors
-
McKimm-Breschkm, J.L.; Sahasrabudhe, A.; Bhck, T.J.; McDonald, M.; Colman, P. M.; Hart, G. J.; Bethell, R. C; Varghese, J. N. Mutations in a conserved residue in the influenza virus neuraminidase active site decreases sensitivity to Neu5Ac2en-derived inhibitors. J. Vir. 1998, 72, 2456-2462.
-
(1998)
J. Vir
, vol.72
, pp. 2456-2462
-
-
McKimm-Breschkm, J.L.1
Sahasrabudhe, A.2
Bhck, T.J.3
McDonald, M.4
Colman, P.M.5
Hart, G.J.6
Bethell, R.C.7
Varghese, J.N.8
-
77
-
-
0035083950
-
Analysis of inhibitor binding in influenza virus neuraminidase
-
Smith, B. J.; Colman, P. M.; von Itzstein, M.; Danylec, B.; Varghese, J. N. Analysis of inhibitor binding in influenza virus neuraminidase. Protein. Sci. 2001, 10, 689-696.
-
(2001)
Protein. Sci
, vol.10
, pp. 689-696
-
-
Smith, B.J.1
Colman, P.M.2
von Itzstein, M.3
Danylec, B.4
Varghese, J.N.5
-
78
-
-
0035083950
-
Analysis of inhibitor binding in influenza virus neuraminidase
-
Smith, B. J.; Colman, P. M.; von Itzstein, M.; Danylec, B.; Varghese, J. N. Analysis of inhibitor binding in influenza virus neuraminidase. Protein. Sci. 2001, 10, 689-696.
-
(2001)
Protein. Sci
, vol.10
, pp. 689-696
-
-
Smith, B.J.1
Colman, P.M.2
von Itzstein, M.3
Danylec, B.4
Varghese, J.N.5
-
79
-
-
0031911783
-
Mutations in a conserved residue in the influenza virus neuraminidase active site decreases sensitivity to Neu5Ac2en-derived inhibitors
-
McKimm-Breschkin, J.L.; Sahasrabudhe, A.; Blick, T.J.; McDonald, M.; Colman, P. M.; Hart, G. J.; Bethell, R. C; Varghese, J. N. Mutations in a conserved residue in the influenza virus neuraminidase active site decreases sensitivity to Neu5Ac2en-derived inhibitors. J. Vir. 1998, 72, 2456-2462.
-
(1998)
J. Vir
, vol.72
, pp. 2456-2462
-
-
McKimm-Breschkin, J.L.1
Sahasrabudhe, A.2
Blick, T.J.3
McDonald, M.4
Colman, P.M.5
Hart, G.J.6
Bethell, R.C.7
Varghese, J.N.8
-
80
-
-
0036210594
-
In vitro characterization of A-315675, a highly potent inhibitor of A and B strain influenza virus neuraminidases and influenza virus replication
-
Kati, W. M.; Montgomery, D.; Carrick, R.; Gubareva, L.; Maring, C; McDaniel, K.; Steffy, K.; Molla, A.; Hayden, F.; Kempf, D.; Kohlbrenner, W. In vitro characterization of A-315675, a highly potent inhibitor of A and B strain influenza virus neuraminidases and influenza virus replication. Antimicrob. Agents Chemother. 2002, 46, 1014-1021.
-
(2002)
Antimicrob. Agents Chemother
, vol.46
, pp. 1014-1021
-
-
Kati, W.M.1
Montgomery, D.2
Carrick, R.3
Gubareva, L.4
Maring, C.5
McDaniel, K.6
Steffy, K.7
Molla, A.8
Hayden, F.9
Kempf, D.10
Kohlbrenner, W.11
-
81
-
-
0031911783
-
Mutations in a conserved residue in the influenza virus neuraminidase active site decreases sensitivity to Neu5Ac2en-derived inhibitors
-
McKimm-Breschkm, J.L.; Sahasrabudhe, A.; Blick, T.J.; McDonald, M.; Colman, P. M.; Hart, G. J.; Bethell, R. C; Varghese, J. N. Mutations in a conserved residue in the influenza virus neuraminidase active site decreases sensitivity to Neu5Ac2en-derived inhibitors. J. Vir. 1998, 72, 2456-2462.
-
(1998)
J. Vir
, vol.72
, pp. 2456-2462
-
-
McKimm-Breschkm, J.L.1
Sahasrabudhe, A.2
Blick, T.J.3
McDonald, M.4
Colman, P.M.5
Hart, G.J.6
Bethell, R.C.7
Varghese, J.N.8
-
82
-
-
0031911783
-
Mutations in a conserved residue in the influenza virus neuraminidase active site decreases sensitivity to Neu5Ac2en-derived inhibitors
-
McKimm-Breschkm, J.L.; Sahasrabudhe, A.; Blick, T.J.; McDonald, M.; Colman, P. M.; Hart, G. J.; Bethell, R. C; Varghese, J. N. Mutations in a conserved residue in the influenza virus neuraminidase active site decreases sensitivity to Neu5Ac2en-derived inhibitors. J. Vir. 1998, 72, 2456-2462.
-
(1998)
J. Vir
, vol.72
, pp. 2456-2462
-
-
McKimm-Breschkm, J.L.1
Sahasrabudhe, A.2
Blick, T.J.3
McDonald, M.4
Colman, P.M.5
Hart, G.J.6
Bethell, R.C.7
Varghese, J.N.8
-
83
-
-
0031911783
-
Mutations in a conserved residue in the influenza virus neuraminidase active site decreases sensitivity to Neu5Ac2en-derived inhibitors
-
McKimm-Breschkm, J.L.; Sahasrabudhe, A.; Blick, T.J.; McDonald, M.; Colman, P. M.; Hart, G. J.; Bethell, R. C; Varghese, J. N. Mutations in a conserved residue in the influenza virus neuraminidase active site decreases sensitivity to Neu5Ac2en-derived inhibitors. J. Vir. 1998, 72, 2456-2462.
-
(1998)
J. Vir
, vol.72
, pp. 2456-2462
-
-
McKimm-Breschkm, J.L.1
Sahasrabudhe, A.2
Blick, T.J.3
McDonald, M.4
Colman, P.M.5
Hart, G.J.6
Bethell, R.C.7
Varghese, J.N.8
-
84
-
-
0032526697
-
Drug design against a shifting target: A structural basis for resistance to inhibitors in a variant of influenza virus neuraminidase
-
Varghese, J. N.; Smith, P. W.; Solhs, S. L.; Blick, T. J.; Sahasrabudhe, A.; McKimm-Breschkm, J. L.; Colman, P. M. Drug design against a shifting target: a structural basis for resistance to inhibitors in a variant of influenza virus neuraminidase. Structure 1998, 6, 735-746.
-
(1998)
Structure
, vol.6
, pp. 735-746
-
-
Varghese, J.N.1
Smith, P.W.2
Solhs, S.L.3
Blick, T.J.4
Sahasrabudhe, A.5
McKimm-Breschkm, J.L.6
Colman, P.M.7
-
85
-
-
0032526697
-
Drug design against a shifting target: A structural basis for resistance to inhibitors in a variant of influenza virus neuraminidase
-
Varghese, J. N.; Smith, P. W.; Solhs, S. L.; Blick, T. J.; Sahasrabudhe, A.; McKimm-Breschkm, J. L.; Colman, P. M. Drug design against a shifting target: a structural basis for resistance to inhibitors in a variant of influenza virus neuraminidase. Structure 1998, 6, 735-746.
-
(1998)
Structure
, vol.6
, pp. 735-746
-
-
Varghese, J.N.1
Smith, P.W.2
Solhs, S.L.3
Blick, T.J.4
Sahasrabudhe, A.5
McKimm-Breschkm, J.L.6
Colman, P.M.7
-
86
-
-
25844474747
-
Neuraminidase inhibitor-resistant influenza viruses may differ substantially in fitness and transmissibility
-
Yen, H. L.; Herlocher, L. M.; Hoffmann, E.; Matrosovich, M. N.; Monto, A. S.; Webster, R. G.; Govorkova, E. A. Neuraminidase inhibitor-resistant influenza viruses may differ substantially in fitness and transmissibility. Antimicrob. Agents Chemother. 2005, 49, 4075-4084.
-
(2005)
Antimicrob. Agents Chemother
, vol.49
, pp. 4075-4084
-
-
Yen, H.L.1
Herlocher, L.M.2
Hoffmann, E.3
Matrosovich, M.N.4
Monto, A.S.5
Webster, R.G.6
Govorkova, E.A.7
-
87
-
-
0032526697
-
Drug design against a shifting target: A structural basis for resistance to inhibitors in a variant of influenza virus neuraminidase
-
Varghese, J. N.; Smith, P. W.; Solhs, S. L.; Blick, T. J.; Sahasrabudhe, A.; McKimm-Breschkm, J. L.; Colman, P. M. Drug design against a shifting target: a structural basis for resistance to inhibitors in a variant of influenza virus neuraminidase. Structure 1998, 6, 735-746.
-
(1998)
Structure
, vol.6
, pp. 735-746
-
-
Varghese, J.N.1
Smith, P.W.2
Solhs, S.L.3
Blick, T.J.4
Sahasrabudhe, A.5
McKimm-Breschkm, J.L.6
Colman, P.M.7
-
88
-
-
0036210594
-
In vitro characterization of A-315675, a highly potent inhibitor of A and B strain influenza virus neuraminidases and influenza virus replication
-
Kati, W. M.; Montgomery, D.; Carrick, R.; Gubareva, L.; Maring, C; McDaniel, K.; Steffy, K.; Molla, A.; Hayden, F.; Kempf, D.; Kohlbrenner, W. In vitro characterization of A-315675, a highly potent inhibitor of A and B strain influenza virus neuraminidases and influenza virus replication. Antimicrob. Agents Chemother. 2002, 46, 1014-1021.
-
(2002)
Antimicrob. Agents Chemother
, vol.46
, pp. 1014-1021
-
-
Kati, W.M.1
Montgomery, D.2
Carrick, R.3
Gubareva, L.4
Maring, C.5
McDaniel, K.6
Steffy, K.7
Molla, A.8
Hayden, F.9
Kempf, D.10
Kohlbrenner, W.11
-
89
-
-
0032526697
-
Drug design against a shifting target: A structural basis for resistance to inhibitors in a variant of influenza virus neuraminidase
-
Varghese, J. N.; Smith, P. W.; Solhs, S. L.; Blick, T. J.; Sahasrabudhe, A.; McKimm-Breschkm, J. L.; Colman, P. M. Drug design against a shifting target: a structural basis for resistance to inhibitors in a variant of influenza virus neuraminidase. Structure 1998, 6, 735-746.
-
(1998)
Structure
, vol.6
, pp. 735-746
-
-
Varghese, J.N.1
Smith, P.W.2
Solhs, S.L.3
Blick, T.J.4
Sahasrabudhe, A.5
McKimm-Breschkm, J.L.6
Colman, P.M.7
-
90
-
-
25844474747
-
Neuraminidase inhibitor-resistant influenza viruses may differ substantially in fitness and transmissibility
-
Yen, H. L.; Herlocher, L. M.; Hoffmann, E.; Matrosovich, M. N.; Monto, A. S.; Webster, R. G.; Govorkova, E. A. Neuraminidase inhibitor-resistant influenza viruses may differ substantially in fitness and transmissibility. Antimicrob. Agents Chemother. 2005, 49, 4075-4084.
-
(2005)
Antimicrob. Agents Chemother
, vol.49
, pp. 4075-4084
-
-
Yen, H.L.1
Herlocher, L.M.2
Hoffmann, E.3
Matrosovich, M.N.4
Monto, A.S.5
Webster, R.G.6
Govorkova, E.A.7
-
91
-
-
0036210594
-
In vitro characterization of A-315675, a highly potent inhibitor of A and B strain influenza virus neuraminidases and influenza virus replication
-
Kati, W. M.; Montgomery, D.; Carrick, R.; Gubareva, L.; Maring, C; McDaniel, K.; Steffy, K.; Molla, A.; Hayden, F.; Kempf, D.; Kohlbrenner, W. In vitro characterization of A-315675, a highly potent inhibitor of A and B strain influenza virus neuraminidases and influenza virus replication. Antimicrob. Agents Chemother. 2002, 46, 1014-1021.
-
(2002)
Antimicrob. Agents Chemother
, vol.46
, pp. 1014-1021
-
-
Kati, W.M.1
Montgomery, D.2
Carrick, R.3
Gubareva, L.4
Maring, C.5
McDaniel, K.6
Steffy, K.7
Molla, A.8
Hayden, F.9
Kempf, D.10
Kohlbrenner, W.11
-
92
-
-
20444378860
-
Structure-based characterization and optimization of novel hydrophobic binding interactions in a series of pyrrolidine influenza neuraminidase inhibitors
-
Maring, C. J.; Stoll, V. S.; Zhao, C; Sun, M.; Krueger, A. C; Stewart, K. D.; Madigan, D. L.; Kati, W. M.; Ju, Y.; Carrick, R. J.; Montgomery, D. A.; Kempf-Grote, A.; Marsh, K. C; Molla, A.; Steffy, K. R.; Sham, H. L.; Laver, W. G.; Gu, Y. G.; Kempf, D. J.; Kohlbrenner, W. E. Structure-based characterization and optimization of novel hydrophobic binding interactions in a series of pyrrolidine influenza neuraminidase inhibitors. J. Med. Chem. 2005, 48, 3980-3990.
-
(2005)
J. Med. Chem
, vol.48
, pp. 3980-3990
-
-
Maring, C.J.1
Stoll, V.S.2
Zhao, C.3
Sun, M.4
Krueger, A.C.5
Stewart, K.D.6
Madigan, D.L.7
Kati, W.M.8
Ju, Y.9
Carrick, R.J.10
Montgomery, D.A.11
Kempf-Grote, A.12
Marsh, K.C.13
Molla, A.14
Steffy, K.R.15
Sham, H.L.16
Laver, W.G.17
Gu, Y.G.18
Kempf, D.J.19
Kohlbrenner, W.E.20
more..
-
93
-
-
0037469141
-
Influenza neuraminidase inhibitors: Structure-based design of a novel inhibitor series
-
Stall, V.; Stewart, K. D.; Marmg, C. J.; Muchmore, S.; Giranda, V.; Gu, Y. G.; Wang, G.; Chen, Y.; Sun, M.; Zhao, C; Kennedy, A. L.; Madigan, D. L.; Xu, Y.; Saldivar, A.; Kati, W.; Laver, G.; Sowin, T.; Sham, H. L.; Greer, J.; Kempf, D. Influenza neuraminidase inhibitors: structure-based design of a novel inhibitor series. Biochemistry 2003, 42, 718-727.
-
(2003)
Biochemistry
, vol.42
, pp. 718-727
-
-
Stall, V.1
Stewart, K.D.2
Marmg, C.J.3
Muchmore, S.4
Giranda, V.5
Gu, Y.G.6
Wang, G.7
Chen, Y.8
Sun, M.9
Zhao, C.10
Kennedy, A.L.11
Madigan, D.L.12
Xu, Y.13
Saldivar, A.14
Kati, W.15
Laver, G.16
Sowin, T.17
Sham, H.L.18
Greer, J.19
Kempf, D.20
more..
-
94
-
-
9644260491
-
Design, synthesis, and structural analysis of inhibitors of influenza neuraminidase containing a 2,3-disubstituted tetrahydrofuran-5-carboxylic acid core
-
Wang, G. T.; Wang, S.; Gentles, R.; Sowin, T.; Marmg, C. J.; Kempf, D. J.; Kati, W. M.; Stall, V.; Stewart, K. D.; Laver, G. Design, synthesis, and structural analysis of inhibitors of influenza neuraminidase containing a 2,3-disubstituted tetrahydrofuran-5-carboxylic acid core. Bioorg. Med. Chem. Lett. 2005,15, 125-128.
-
(2005)
Bioorg. Med. Chem. Lett
, vol.15
, pp. 125-128
-
-
Wang, G.T.1
Wang, S.2
Gentles, R.3
Sowin, T.4
Marmg, C.J.5
Kempf, D.J.6
Kati, W.M.7
Stall, V.8
Stewart, K.D.9
Laver, G.10
-
95
-
-
9644260491
-
Design, synthesis, and structural analysis of inhibitors of influenza neuraminidase containing a 2,3-disubstituted tetrahydrofuran-5-carboxylic acid core
-
Wang, G. T.; Wang, S.; Gentles, R.; Sowin, T.; Marmg, C. J.; Kempf, D. J.; Kati, W. M.; Stall, V.; Stewart, K. D.; Laver, G. Design, synthesis, and structural analysis of inhibitors of influenza neuraminidase containing a 2,3-disubstituted tetrahydrofuran-5-carboxylic acid core. Bioorg. Med. Chem. Lett. 2005,15, 125-128.
-
(2005)
Bioorg. Med. Chem. Lett
, vol.15
, pp. 125-128
-
-
Wang, G.T.1
Wang, S.2
Gentles, R.3
Sowin, T.4
Marmg, C.J.5
Kempf, D.J.6
Kati, W.M.7
Stall, V.8
Stewart, K.D.9
Laver, G.10
-
96
-
-
0028940702
-
Structures of aromatic inhibitors of influenza virus neuraminidase
-
Jedrzejas, M. J.; Singh, S.; Brouillette, W. J.; Laver, W. G.; Air, G. M.; Luo, M. Structures of aromatic inhibitors of influenza virus neuraminidase. Biochemistry 1995, 34, 3144-3151.
-
(1995)
Biochemistry
, vol.34
, pp. 3144-3151
-
-
Jedrzejas, M.J.1
Singh, S.2
Brouillette, W.J.3
Laver, W.G.4
Air, G.M.5
Luo, M.6
-
97
-
-
0032510373
-
Dihydropyrancarboxamides related to zanamivir: A new series of inhibitors of influenza virus sialidases. 2. Crystallographic and molecular modeling study of complexes of 4-amino-4H-pyran-6-carboxamides and sialidase from influenza virus types A and B
-
Taylor, N. R.; Cleasby, A.; Singh, O.; Skarzynski, T.; Wonacott, A. J.; Smith, P. W.; Solhs, S. L; Howes, P. D.; Cherry, P. C; Bethell, R.; Colman, P.; Varghese, J. Dihydropyrancarboxamides related to zanamivir: a new series of inhibitors of influenza virus sialidases. 2. Crystallographic and molecular modeling study of complexes of 4-amino-4H-pyran-6-carboxamides and sialidase from influenza virus types A and B. J. Med. Chem. 1998, 41, 798-807.
-
(1998)
J. Med. Chem
, vol.41
, pp. 798-807
-
-
Taylor, N.R.1
Cleasby, A.2
Singh, O.3
Skarzynski, T.4
Wonacott, A.J.5
Smith, P.W.6
Solhs, S.L.7
Howes, P.D.8
Cherry, P.C.9
Bethell, R.10
Colman, P.11
Varghese, J.12
-
98
-
-
0028925854
-
-
White, C. L.; Janakiraman, M. N.; Laver, W. G.; Philippon, C; Vasella, A.; Air, G. M.; Luo, M. A sialic acid-derived phosphonate analog inhibits different strains of influenza virus neuraminidase with different efficiencies. J. Mol. Biol. 1995 245, 623-634.
-
White, C. L.; Janakiraman, M. N.; Laver, W. G.; Philippon, C; Vasella, A.; Air, G. M.; Luo, M. A sialic acid-derived phosphonate analog inhibits different strains of influenza virus neuraminidase with different efficiencies. J. Mol. Biol. 1995 245, 623-634.
-
-
-
-
99
-
-
15644379365
-
-
Smith, P. W.; Solhs, S. L.; Howes, P. D.; Cherry, P. C; Starkey, I. D.; Cobley, K. N.; Weston, H.; Scicinski, J.; Merritt, A.; Whittington, A.; Wyatt, P.; Taylor, N.; Green, D.; Bethell, R.; Madar, S.; Fenton, R. J.; Morley, P. J.; Pateman, T.; Beresford, A. Dihydropyrancarboxamides related to zanamivir: a new series of inhibitors of influenza virus sialidases. 1. Discovery, synthesis, biological activity, and structure-activity relationships of 4-guanidino- and 4-amino-4H-pyran-6-carboxamides. J. Med. Chem. 1998, 41, 787-797.
-
Smith, P. W.; Solhs, S. L.; Howes, P. D.; Cherry, P. C; Starkey, I. D.; Cobley, K. N.; Weston, H.; Scicinski, J.; Merritt, A.; Whittington, A.; Wyatt, P.; Taylor, N.; Green, D.; Bethell, R.; Madar, S.; Fenton, R. J.; Morley, P. J.; Pateman, T.; Beresford, A. Dihydropyrancarboxamides related to zanamivir: a new series of inhibitors of influenza virus sialidases. 1. Discovery, synthesis, biological activity, and structure-activity relationships of 4-guanidino- and 4-amino-4H-pyran-6-carboxamides. J. Med. Chem. 1998, 41, 787-797.
-
-
-
-
100
-
-
0028940702
-
Structures of aromatic inhibitors of influenza virus neuraminidase
-
Jedrzejas, M. J.; Singh, S.; Brouillette, W. J.; Laver, W. G.; Air, G. M.; Luo, M. Structures of aromatic inhibitors of influenza virus neuraminidase. Biochemistry 1995, 34, 3144-3151.
-
(1995)
Biochemistry
, vol.34
, pp. 3144-3151
-
-
Jedrzejas, M.J.1
Singh, S.2
Brouillette, W.J.3
Laver, W.G.4
Air, G.M.5
Luo, M.6
-
101
-
-
0033550314
-
Novel aromatic inhibitors of influenza virus neuraminidase make selective interactions with conserved residues and water molecules in the active site
-
Fmley, J. B.; Atigadda, V. R.; Duarte, F.; Zhao, J. J.; Brouillette, W. J.; Air, G. M.; Luo, M. Novel aromatic inhibitors of influenza virus neuraminidase make selective interactions with conserved residues and water molecules in the active site. J. Mol. Biol. 1999, 293, 1107-1119.
-
(1999)
J. Mol. Biol
, vol.293
, pp. 1107-1119
-
-
Fmley, J.B.1
Atigadda, V.R.2
Duarte, F.3
Zhao, J.J.4
Brouillette, W.J.5
Air, G.M.6
Luo, M.7
-
102
-
-
0033490930
-
Hydrophobic benzoic acids as inhibitors of influenza neuraminidase
-
Atigadda, V. R.; Brouillette, W. J.; Duarte, F.; Babu, Y. S.; Bantia, S.; Chand, P.; Chu, N.; Montgomery, J. A.; Walsh, D. A.; Sudbeck, E.; Finley, J.; Air, G. M.; Luo, M.; Laver, G. W. Hydrophobic benzoic acids as inhibitors of influenza neuraminidase. Bioorg. Med. Chem. 1999, 7, 2487-2497.
-
(1999)
Bioorg. Med. Chem
, vol.7
, pp. 2487-2497
-
-
Atigadda, V.R.1
Brouillette, W.J.2
Duarte, F.3
Babu, Y.S.4
Bantia, S.5
Chand, P.6
Chu, N.7
Montgomery, J.A.8
Walsh, D.A.9
Sudbeck, E.10
Finley, J.11
Air, G.M.12
Luo, M.13
Laver, G.W.14
-
103
-
-
16644374078
-
-
Lommer, B. S.; Ali, S. M.; Bajpai, S. N.; Brouillette, W. J. ; Air, G. M.; Luo, M. A benzoic acid inhibitor induces a novel conformational change in the active site of Influenza B virus neuraminidase Acta Crystallogr. 2004, D60, 1017-1023.
-
Lommer, B. S.; Ali, S. M.; Bajpai, S. N.; Brouillette, W. J. ; Air, G. M.; Luo, M. A benzoic acid inhibitor induces a novel conformational change in the active site of Influenza B virus neuraminidase Acta Crystallogr. 2004, D60, 1017-1023.
-
-
-
-
104
-
-
16644374078
-
-
Lommer, B. S.; Ali, S. M.; Bajpai, S. N.; Brouillette, W. J. ; Air, G. M.; Luo, M. A benzoic acid inhibitor induces a novel conformational change in the active site of Influenza B virus neuraminidase Acta Crystallogr. 2004, D60, 1017-1023.
-
Lommer, B. S.; Ali, S. M.; Bajpai, S. N.; Brouillette, W. J. ; Air, G. M.; Luo, M. A benzoic acid inhibitor induces a novel conformational change in the active site of Influenza B virus neuraminidase Acta Crystallogr. 2004, D60, 1017-1023.
-
-
-
-
105
-
-
0033550314
-
Novel aromatic inhibitors of influenza virus neuraminidase make selective interactions with conserved residues and water molecules in the active site
-
Finley, J. B.; Atigadda, V. R; Duarte, F.; Zhao, J. J.; Brouillette, W. J.; Air, G. M.; Luo, M. Novel aromatic inhibitors of influenza virus neuraminidase make selective interactions with conserved residues and water molecules in the active site. J. Mol. Biol. 1999, 293, 1107-1119.
-
(1999)
J. Mol. Biol
, vol.293
, pp. 1107-1119
-
-
Finley, J.B.1
Atigadda, V.R.2
Duarte, F.3
Zhao, J.J.4
Brouillette, W.J.5
Air, G.M.6
Luo, M.7
-
106
-
-
0033168078
-
Potent inhibition of influenza sialidase by a benzoic acid containing a 2-pyrrolidinone substituent
-
Atigadda, V. R.; Brouillette, W. J.; Duarte, F.; Ali, S. M.; Babu, Y. S.; Bantia, S.; Chand, P.; Chu, N; Montgomery, J. A.; Walsh, D. A.; Sudbeck, E. A.; Finley, J.; Luo, M.; Air, G. M.; Laver, G. W. Potent inhibition of influenza sialidase by a benzoic acid containing a 2-pyrrolidinone substituent. J. Med. Chem. 1999, 42, 2332-2343.
-
(1999)
J. Med. Chem
, vol.42
, pp. 2332-2343
-
-
Atigadda, V.R.1
Brouillette, W.J.2
Duarte, F.3
Ali, S.M.4
Babu, Y.S.5
Bantia, S.6
Chand, P.7
Chu, N.8
Montgomery, J.A.9
Walsh, D.A.10
Sudbeck, E.A.11
Finley, J.12
Luo, M.13
Air, G.M.14
Laver, G.W.15
-
107
-
-
0033550314
-
Novel aromatic inhibitors of influenza virus neuraminidase make selective interactions with conserved residues and water molecules in the active site
-
Finley, J. B.; Atigadda, V. R.; Duarte, F.; Zhao, J. J.; Bromllette, W. J.; Air, G. M.; Luo, M. Novel aromatic inhibitors of influenza virus neuraminidase make selective interactions with conserved residues and water molecules in the active site. J. Mol. Biol. 1999, 293, 1107-1119.
-
(1999)
J. Mol. Biol
, vol.293
, pp. 1107-1119
-
-
Finley, J.B.1
Atigadda, V.R.2
Duarte, F.3
Zhao, J.J.4
Bromllette, W.J.5
Air, G.M.6
Luo, M.7
|