A new tyrosyl radical on Phe208 as ligand to the diiron center in Escherichia coli ribonucleotide reductase, mutant R2-Y122H: Combined x-ray diffraction and EPR/ENDOR studies

Journal of Biological Chemistry

Volumn 280, Issue 12, 2005, Pages 11233-11246

  Kolberg, Matthias ^a,b   Logan, Derek T ^c,d   Bleifuss, Günther ^a   Pötsch, Stephan ^d   Sjöberg, Britt Marie ^d   Gräslund, Astrid ^d   Lubitz, Wolfgang ^e   Lassmann, Günter ^e   Lendzian, Friedhelm ^a  

^a TECHNISCHE UNIVERSITÄT BERLIN   (Germany)

^b UNIVERSITY OF OSLO   (Norway)

^c LUND UNIVERSITY   (Sweden)

^d STOCKHOLM UNIVERSITY   (Sweden)

^e MAX PLANCK INSTITUTE FOR CHEMICAL ENERGY CONVERSION   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; ENZYMES; IRON; NUCLEIC ACIDS; OXIDATION; REACTION KINETICS; REDUCTION;

IRON CENTERS; MOLECULAR OXYGEN; REDUCTIVE CLEAVAGE; TYROSINE;

ESCHERICHIA COLI;

HISTIDINE; HYDROCARBON; IRON; METHANE MONOOXYGENASE; PHENYLALANINE; RADICAL; RIBONUCLEOTIDE REDUCTASE; TYROSINE;

ARTICLE; BACTERIAL STRAIN; CHEMICAL LABELING; CRYSTALLIZATION; ELECTRON NUCLEAR DOUBLE RESONANCE; ELECTRON SPIN RESONANCE; ENZYME ACTIVITY; ESCHERICHIA COLI; HYDROXYLATION; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MUTANT; OXIDATION REDUCTION POTENTIAL; OXYGENATION; PRIORITY JOURNAL; PROTEIN ANALYSIS; SITE DIRECTED MUTAGENESIS; SUBSTITUTION REACTION; X RAY DIFFRACTION;

ELECTRON SPIN RESONANCE SPECTROSCOPY; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; FREE RADICALS; LIGANDS; MODELS, MOLECULAR; RIBONUCLEOTIDE REDUCTASES; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; TYROSINE; X-RAY DIFFRACTION;

ESCHERICHIA COLI;

EID: 15744363736     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M414634200     Document Type: Article

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