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Volumn 276, Issue 10, 2009, Pages 2736-2751

Interactions between the amyloid precursor protein C-terminal domain and G proteins mediate calcium dysregulation and amyloid β toxicity in Alzheimer's disease

Author keywords

Caspase; Endoplasmic reticulum; Neurodegeneration; Voltage gated calcium channels

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; CALCIUM; GO PROTEIN; GUANINE NUCLEOTIDE BINDING PROTEIN; PERTUSSIS TOXIN; PROTEIN DERIVATIVE; UNCLASSIFIED DRUG;

EID: 65349144513     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2009.06997.x     Document Type: Article
Times cited : (21)

References (63)
  • 1
    • 0035002421 scopus 로고    scopus 로고
    • Neuropathology of Alzheimer's disease and other dementias
    • DOI 10.1016/S0749-0690(05)70066-5
    • Dickson DW (2001) Neuropathology of Alzheimer's disease and other dementias. Clin Geriatr Med 17, 209 228. (Pubitemid 32429328)
    • (2001) Clinics in Geriatric Medicine , vol.17 , Issue.2 , pp. 209-228
    • Dickson, D.W.1
  • 2
    • 34548703093 scopus 로고    scopus 로고
    • Amyloid beta protein as a marker or risk factor of Alzheimer's disease
    • DOI 10.2174/156720507781788891
    • Mehta PD (2007) Amyloid beta protein as a marker or risk factor of Alzheimer's disease. Curr Alzheimer Res 4, 359 363. (Pubitemid 47416628)
    • (2007) Current Alzheimer Research , vol.4 , Issue.4 , pp. 359-363
    • Mehta, P.D.1
  • 4
    • 0142179222 scopus 로고    scopus 로고
    • Caspase cleavage of the amyloid precursor protein modulates amyloid -protein toxicity
    • DOI 10.1046/j.1471-4159.2003.02059.x
    • Lu DC, Soriano S, Bredesen DE Koo EH (2003) Caspase cleavage of the amyloid precursor protein modulates amyloid beta-protein toxicity. J Neurochem 87, 733 741. (Pubitemid 37310638)
    • (2003) Journal of Neurochemistry , vol.87 , Issue.3 , pp. 733-741
    • Lu, D.C.1    Soriano, S.2    Bredesen, D.E.3    Koo, E.H.4
  • 5
    • 33845661843 scopus 로고    scopus 로고
    • Abeta induces cell death by direct interaction with its cognate extracellular domain on APP (APP 597-624)
    • Shaked GM, Kummer MP, Lu DC, Galvan V, Bredesen DE Koo EH (2006) Abeta induces cell death by direct interaction with its cognate extracellular domain on APP (APP 597-624). FASEB J 20, 1254 1256.
    • (2006) FASEB J , vol.20 , pp. 1254-1256
    • Shaked, G.M.1    Kummer, M.P.2    Lu, D.C.3    Galvan, V.4    Bredesen, D.E.5    Koo, E.H.6
  • 7
    • 0027447656 scopus 로고
    • Alzheimer amyloid protein precursor complexes with brain GTP-binding protein G(o)
    • DOI 10.1038/362075a0
    • Nishimoto I, Okamoto T, Matsuura Y, Takahashi S, Murayama Y Ogata E (1993) Alzheimer amyloid protein precursor complexes with brain GTP-binding protein G(o). Nature 362, 75 79. (Pubitemid 23087295)
    • (1993) Nature , vol.362 , Issue.6415 , pp. 75-79
    • Nishimoto, I.1    Okamoto, T.2    Matsuura, Y.3    Takahashi, S.4    Okamoto, T.5    Murayama, Y.6    Ogata, E.7
  • 8
    • 28244464899 scopus 로고    scopus 로고
    • The insect homologue of the amyloid precursor protein interacts with the heterotrimeric G protein Go in an identified population of migratory neurons
    • DOI 10.1016/j.ydbio.2005.09.029, PII S0012160605006366
    • Swanson TL, Knittel LM, Coate TM, Farley SM, Snyder MA Copenhaver PF (2005) The insect homologue of the amyloid precursor protein interacts with the heterotrimeric G protein Go alpha in an identified population of migratory neurons. Dev Biol 288, 160 178. (Pubitemid 41713161)
    • (2005) Developmental Biology , vol.288 , Issue.1 , pp. 160-178
    • Swanson, T.L.1    Knittel, L.M.2    Coate, T.M.3    Farley, S.M.4    Snyder, M.A.5    Copenhaver, P.F.6
  • 11
    • 0026803223 scopus 로고
    • G protein-coupled mechanisms and nervous signaling
    • Hille B (1992) G protein-coupled mechanisms and nervous signaling. Neuron 9, 187 195.
    • (1992) Neuron , vol.9 , pp. 187-195
    • Hille, B.1
  • 12
    • 0027973423 scopus 로고
    • Modulation of ion-channel function by G-protein-coupled receptors
    • Hille B (1994) Modulation of ion-channel function by G-protein-coupled receptors. Trends Neurosci 17, 531 536. (Pubitemid 124000831)
    • (1994) Trends in Neurosciences , vol.17 , Issue.12 , pp. 531-536
    • Hille, B.1
  • 14
    • 33846270026 scopus 로고    scopus 로고
    • Introducing an alternative biophysical method to analyze direct G protein regulation of voltage-dependent calcium channels
    • Weiss N De Waard M (2006) Introducing an alternative biophysical method to analyze direct G protein regulation of voltage-dependent calcium channels. J Neurosci Methods 160, 26 36.
    • (2006) J Neurosci Methods , vol.160 , pp. 26-36
    • Weiss, N.1    De Waard, M.2
  • 15
    • 0036469258 scopus 로고    scopus 로고
    • 35SGTPS binding correlates with Alzheimer's disease neurofibrillary pathology in entorhinal cortex and CA1 hippocampal subfield
    • DOI 10.1002/jnr.10125
    • Garcia-Jimenez A, Cowburn RF, Ohm TG, Lasn H, Winblad B, Bogdanovic N Fastbom J (2002) Loss of stimulatory effect of guanosine triphosphate on (35)SGTPgammaS binding correlates with Alzheimer's disease neurofibrillary pathology in entorhinal cortex and CA1 hippocampal subfield. J Neurosci Res 67, 388 398. (Pubitemid 34137146)
    • (2002) Journal of Neuroscience Research , vol.67 , Issue.3 , pp. 388-398
    • Garca-Jimnez, A.1    Cowburn, R.F.2    Ohm, T.G.3    Lasn, H.4    Winblad, B.5    Bogdanovic, N.6    Fastbom, J.7
  • 17
    • 0028031955 scopus 로고
    • Regionally selective alterations in G protein subunit levels in the Alzheimer's disease brain
    • DOI 10.1016/0006-8993(94)91017-0
    • O'Neill C, Wiehager B, Fowler CJ, Ravid R, Winblad B Cowburn RF (1994) Regionally selective alterations in G protein subunit levels in the Alzheimer's disease brain. Brain Res 636, 193 201. (Pubitemid 24044635)
    • (1994) Brain Research , vol.636 , Issue.2 , pp. 193-201
    • O'Neill, C.1    Wiehager, B.2    Fowler, C.J.3    Ravid, R.4    Winblad, B.5    Cowburn, R.F.6
  • 19
    • 38849132181 scopus 로고    scopus 로고
    • Role of calcium in the pathogenesis of Alzheimer's disease and transgenic models
    • Green KN, Smith IF Laferla FM (2007) Role of calcium in the pathogenesis of Alzheimer's disease and transgenic models. Subcell Biochem 45, 507 521.
    • (2007) Subcell Biochem , vol.45 , pp. 507-521
    • Green, K.N.1    Smith, I.F.2    Laferla, F.M.3
  • 20
    • 0042268132 scopus 로고    scopus 로고
    • Dysregulation of calcium in Alzheimer's disease
    • Bojarski L, Herms J Kuznicki J (2008) Calcium dysregulation in Alzheimer's disease. Neurochem Int 52, 621 633. (Pubitemid 36916950)
    • (2003) Acta Neurobiologiae Experimentalis , vol.63 , Issue.3 , pp. 171-183
    • Brzyska, M.1    Elbaum, D.2
  • 22
    • 0035951774 scopus 로고    scopus 로고
    • The Role of G Protein Activation in the Toxicity of Amyloidogenic A-U-40, A(25-35), and Bovine Calcitonin
    • DOI 10.1074/jbc.M005800200
    • Rymer DL Good TA (2001) The role of G protein activation in the toxicity of amyloidogenic Abeta-(1-40), Abeta-(25-35), and bovine calcitonin. J Biol Chem 276, 2523 2530. (Pubitemid 33649104)
    • (2001) Journal of Biological Chemistry , vol.276 , Issue.4 , pp. 2523-2530
    • Rymer, D.L.1    Good, T.A.2
  • 23
    • 0023092620 scopus 로고
    • 0, regulates neuronal calcium channels
    • DOI 10.1038/325445a0
    • Hescheler J, Rosenthal W, Trautwein W Schultz G (1987) The GTP-binding protein, Go, regulates neuronal calcium channels. Nature 325, 445 447. (Pubitemid 17056412)
    • (1987) Nature , vol.325 , Issue.6103 , pp. 445-447
    • Hescheler, J.1    Rosenthal, W.2    Trautwein, W.3    Schultz, G.4
  • 25
    • 0347479366 scopus 로고    scopus 로고
    • Accumulation of caspase cleaved amyloid precursor protein represents an early neurodegenerative event in aging and in Alzheimer's disease
    • DOI 10.1016/j.nbd.2003.07.006
    • Zhao M, Su J, Head E Cotman CW (2003) Accumulation of caspase cleaved amyloid precursor protein represents an early neurodegenerative event in aging and in Alzheimer's disease. Neurobiol Dis 14, 391 403. (Pubitemid 37543518)
    • (2003) Neurobiology of Disease , vol.14 , Issue.3 , pp. 391-403
    • Zhao, M.1    Su, J.2    Head, E.3    Cotman, C.W.4
  • 26
    • 0029805132 scopus 로고    scopus 로고
    • The phosphotyrosine interaction domains of X11 and FE65 bind to distinct sites on the YENPTY motif of amyloid precursor protein
    • Borg JP, Ooi J, Levy E Margolis B (1996) The phosphotyrosine interaction domains of X11 and FE65 bind to distinct sites on the YENPTY motif of amyloid precursor protein. Mol Cell Biol 16, 6229 6241. (Pubitemid 26360983)
    • (1996) Molecular and Cellular Biology , vol.16 , Issue.11 , pp. 6229-6241
    • Borg, J.-P.1    Ooi, J.2    Levy, E.3    Margolis, B.4
  • 27
    • 33845324145 scopus 로고    scopus 로고
    • C-terminal fragments of amyloid precursor protein exert neurotoxicity by inducing glycogen synthase kinase-3beta expression
    • Kim HS, Kim EM, Lee JP, Park CH, Kim S, Seo JH, Chang KA, Yu E, Jeong SJ, Chong YH et al. (2003) C-terminal fragments of amyloid precursor protein exert neurotoxicity by inducing glycogen synthase kinase-3beta expression. FASEB J 17, 1951 1953.
    • (2003) FASEB J , vol.17 , pp. 1951-1953
    • Kim, H.S.1    Kim, E.M.2    Lee, J.P.3    Park, C.H.4    Kim, S.5    Seo, J.H.6    Chang, K.A.7    Yu, E.8    Jeong, S.J.9    Chong, Y.H.10
  • 30
    • 37049036403 scopus 로고    scopus 로고
    • APP-based neuroprotective strategies
    • DOI 10.2174/156720507783018253
    • Bredesen DE Rabizadeh S (2007) APP-based neuroprotective strategies. Curr Alzheimer Res 4, 541 543. (Pubitemid 350248386)
    • (2007) Current Alzheimer Research , vol.4 , Issue.5 , pp. 541-543
    • Bredesen, D.E.1    Rabizadeh, S.2
  • 31
    • 0028670272 scopus 로고
    • Beta-amyloid Ca(2+)-channel hypothesis for neuronal death in Alzheimer disease
    • Arispe N, Pollard HB Rojas E (1994) Beta-amyloid Ca(2+)-channel hypothesis for neuronal death in Alzheimer disease. Mol Cell Biochem 140, 119 125.
    • (1994) Mol Cell Biochem , vol.140 , pp. 119-125
    • Arispe, N.1    Pollard, H.B.2    Rojas, E.3
  • 32
    • 33845898816 scopus 로고    scopus 로고
    • Deficits in synaptic transmission and learning in amyloid precursor protein (APP) transgenic mice require C-terminal cleavage of APP
    • DOI 10.1523/JNEUROSCI.4180-06.2006
    • Saganich MJ, Schroeder BE, Galvan V, Bredesen DE, Koo EH Heinemann SF (2006) Deficits in synaptic transmission and learning in amyloid precursor protein (APP) transgenic mice require C-terminal cleavage of APP. J Neurosci 26, 13428 13436. (Pubitemid 46026474)
    • (2006) Journal of Neuroscience , vol.26 , Issue.52 , pp. 13428-13436
    • Saganich, M.J.1    Schroeder, B.E.2    Galvan, V.3    Bredesen, D.E.4    Koo, E.H.5    Heinemann, S.F.6
  • 35
    • 33750617659 scopus 로고    scopus 로고
    • Overexpression of GRK2 in Alzheimer disease and in a chronic hypoperfusion rat model is an early marker of brain mitochondrial lesions
    • Obrenovich ME, Smith MA, Siedlak SL, Chen SG, de la Torre JC, Perry G Aliev G (2006) Overexpression of GRK2 in Alzheimer disease and in a chronic hypoperfusion rat model is an early marker of brain mitochondrial lesions. Neurotox Res 10, 43 56.
    • (2006) Neurotox Res , vol.10 , pp. 43-56
    • Obrenovich, M.E.1    Smith, M.A.2    Siedlak, S.L.3    Chen, S.G.4    De La Torre, J.C.5    Perry, G.6    Aliev, G.7
  • 36
    • 33845207273 scopus 로고    scopus 로고
    • Critical role of methionine-722 in the stimulation of human brain G-proteins and neurotoxicity induced by London familial Alzheimer's disease (FAD) mutated V717G-APP(714-723)
    • Reis K, Zharkovsky A, Bogdanovic N, Karelson E Land T (2007) Critical role of methionine-722 in the stimulation of human brain G-proteins and neurotoxicity induced by London familial Alzheimer's disease (FAD) mutated V717G-APP(714-723). Neuroscience 144, 571 578.
    • (2007) Neuroscience , vol.144 , pp. 571-578
    • Reis, K.1    Zharkovsky, A.2    Bogdanovic, N.3    Karelson, E.4    Land, T.5
  • 37
    • 0033898887 scopus 로고    scopus 로고
    • Carboxyl-terminal fragment of Alzheimer's APP destabilizes calcium homeostasis and renders neuronal cells vulnerable to excitotoxicity
    • Kim HS, Park CH, Cha SH, Lee JH, Lee S, Kim Y, Rah JC, Jeong SJ Suh YH (2000) Carboxyl-terminal fragment of Alzheimer's APP destabilizes calcium homeostasis and renders neuronal cells vulnerable to excitotoxicity. FASEB J 14, 1508 1517. (Pubitemid 30639070)
    • (2000) FASEB Journal , vol.14 , Issue.11 , pp. 1508-1517
    • Kim, H.-S.1    Hyoung Park, C.2    Ho Cha, S.3    Lee, J.-H.4    Lee, S.5    Kim, Y.6    Rah, J.-C.7    Jeong, S.-J.8    Suh, Y.-H.9
  • 38
    • 15244352734 scopus 로고    scopus 로고
    • 3 signaling, and Alzheimer's disease
    • DOI 10.1177/1073858404270899
    • Stutzmann GE (2005) Calcium dysregulation, IP3 signaling, and Alzheimer's disease. Neuroscientist 11, 110 115. (Pubitemid 40388493)
    • (2005) Neuroscientist , vol.11 , Issue.2 , pp. 110-115
    • Stutzmann, G.E.1
  • 39
    • 0028651951 scopus 로고
    • Calcium hypothesis of Alzheimer's disease and brain aging
    • Khachaturian ZS (1994) Calcium hypothesis of Alzheimer's disease and brain aging. Ann NY Acad Sci 747, 1 11.
    • (1994) Ann NY Acad Sci , vol.747 , pp. 1-11
    • Khachaturian, Z.S.1
  • 43
    • 20444496481 scopus 로고    scopus 로고
    • Calcium dysregulation and membrane disruption as a ubiquitous neurotoxic mechanism of soluble amyloid oligomers
    • DOI 10.1074/jbc.M500997200
    • Demuro A, Mina E, Kayed R, Milton SC, Parker I Glabe CG (2005) Calcium dysregulation and membrane disruption as a ubiquitous neurotoxic mechanism of soluble amyloid oligomers. J Biol Chem 280, 17294 17300. (Pubitemid 41389198)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.17 , pp. 17294-17300
    • Demuro, A.1    Mina, E.2    Kayed, R.3    Milton, S.C.4    Parker, I.5    Glabe, C.G.6
  • 44
    • 33751516396 scopus 로고    scopus 로고
    • Soluble amyloid oligomers increase bilayer conductance by altering dielectric structure
    • Sokolov Y, Kozak JA, Kayed R, Chanturiya A, Glabe C Hall JE (2006) Soluble amyloid oligomers increase bilayer conductance by altering dielectric structure. J Gen Physiol 128, 637 647.
    • (2006) J Gen Physiol , vol.128 , pp. 637-647
    • Sokolov, Y.1    Kozak, J.A.2    Kayed, R.3    Chanturiya, A.4    Glabe, C.5    Hall, J.E.6
  • 45
    • 0028169905 scopus 로고
    • Secreted forms of -amyloid precursor protein protect hippocampal neurons against amyloid -peptide-induced oxidative injury
    • DOI 10.1006/exnr.1994.1107
    • Goodman Y Mattson MP (1994) Secreted forms of beta-amyloid precursor protein protect hippocampal neurons against amyloid beta-peptide-induced oxidative injury. Exp Neurol 128, 1 12. (Pubitemid 24278360)
    • (1994) Experimental Neurology , vol.128 , Issue.1 , pp. 1-12
    • Goodman, Y.1    Mattson, M.P.2
  • 47
    • 0026570528 scopus 로고
    • Beta-amyloid peptides destabilize calcium homeostasis and render human cortical neurons vulnerable to excitotoxicity
    • Mattson MP, Cheng B, Davis D, Bryant K, Lieberburg I Rydel RE (1992) Beta-amyloid peptides destabilize calcium homeostasis and render human cortical neurons vulnerable to excitotoxicity. J Neurosci 12, 376 389.
    • (1992) J Neurosci , vol.12 , pp. 376-389
    • Mattson, M.P.1    Cheng, B.2    Davis, D.3    Bryant, K.4    Lieberburg, I.5    Rydel, R.E.6
  • 48
    • 1442323991 scopus 로고    scopus 로고
    • Intraneuronal amyloid-1-42 production triggered by sustained increase of cytosolic calcium concentration induces neuronal death
    • DOI 10.1046/j.1471-4159.2003.02227.x
    • Pierrot N, Ghisdal P, Caumont AS Octave JN (2004) Intraneuronal amyloid-beta1-42 production triggered by sustained increase of cytosolic calcium concentration induces neuronal death. J Neurochem 88, 1140 1150. (Pubitemid 38280681)
    • (2004) Journal of Neurochemistry , vol.88 , Issue.5 , pp. 1140-1150
    • Pierrot, N.1    Ghisdal, P.2    Caumont, A.-S.3    Octave, J.-N.4
  • 49
    • 33846031988 scopus 로고    scopus 로고
    • Calcium-mediated transient phosphorylation of tau and amyloid precursor protein followed by intraneuronal amyloid- accumulation
    • DOI 10.1074/jbc.M606015200
    • Pierrot N, Santos SF, Feyt C, Morel M, Brion JP Octave JN (2006) Calcium-mediated transient phosphorylation of tau and amyloid precursor protein followed by intraneuronal amyloid-beta accumulation. J Biol Chem 281, 39907 39914. (Pubitemid 46041794)
    • (2006) Journal of Biological Chemistry , vol.281 , Issue.52 , pp. 39907-39914
    • Pierrot, N.1    Santos, S.F.2    Feyt, C.3    Morel, M.4    Brion, J.-P.5    Octave, J.-N.6
  • 50
    • 0028204224 scopus 로고
    • Calcium ionophore increases amyloid peptide production by cultured cells
    • Querfurth HW Selkoe DJ (1994) Calcium ionophore increases amyloid beta peptide production by cultured cells. Biochemistry 33, 4550 4561. (Pubitemid 24145103)
    • (1994) Biochemistry , vol.33 , Issue.15 , pp. 4550-4561
    • Querfurth, H.W.1    Selkoe, D.J.2
  • 51
    • 49249118742 scopus 로고    scopus 로고
    • Neurotoxic effect of oligomeric and fibrillar species of amyloid-beta peptide 1-42: Involvement of endoplasmic reticulum calcium release in oligomer-induced cell death
    • Resende R, Ferreiro E, Pereira C Resende de Oliveira C (2008) Neurotoxic effect of oligomeric and fibrillar species of amyloid-beta peptide 1-42: involvement of endoplasmic reticulum calcium release in oligomer-induced cell death. Neuroscience 155, 725 737.
    • (2008) Neuroscience , vol.155 , pp. 725-737
    • Resende, R.1    Ferreiro, E.2    Pereira, C.3    Resende De Oliveira, C.4
  • 55
    • 0030608841 scopus 로고    scopus 로고
    • +- ATPase activity, glucose transport, and glutamate transport induced by amyloid -peptide and iron
    • DOI 10.1002/(SICI)1097-4547(19971115)50:4<522::AID-JNR3>3.0.CO;2-G
    • +-ATPase activity, glucose transport, and glutamate transport induced by amyloid beta-peptide and iron. J Neurosci Res 50, 522 530. (Pubitemid 27510035)
    • (1997) Journal of Neuroscience Research , vol.50 , Issue.4 , pp. 522-530
    • Keller, J.N.1    Germeyer, A.2    Begley, J.G.3    Mattson, M.P.4
  • 56
  • 57
    • 48949120507 scopus 로고    scopus 로고
    • Differential dissociation of G protein heterotrimers
    • Digby GJ, Sethi PR Lambert NA (2008) Differential dissociation of G protein heterotrimers. J Physiol 586, 3325 3335.
    • (2008) J Physiol , vol.586 , pp. 3325-3335
    • Digby, G.J.1    Sethi, P.R.2    Lambert, N.A.3
  • 58
    • 27844496141 scopus 로고    scopus 로고
    • Heterotrimeric G-protein -subunit adopts a preactivated conformation when associated with -subunits
    • DOI 10.1074/jbc.M505259200
    • Abdulaev NG, Ngo T, Zhang C, Dinh A, Brabazon DM, Ridge KD Marino JP (2005) Heterotrimeric G-protein alpha-subunit adopts a 'preactivated' conformation when associated with betagamma-subunits. J Biol Chem 280, 38071 38080. (Pubitemid 41642421)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.45 , pp. 38071-38080
    • Abdulaev, N.G.1    Ngo, T.2    Zhang, C.3    Dinh, A.4    Brabazon, D.M.5    Ridge, K.D.6    Marino, J.P.7
  • 59
    • 0028985267 scopus 로고
    • The precursor protein of non-A beta component of Alzheimer's disease amyloid is a presynaptic protein of the central nervous system
    • Iwai A, Masliah E, Yoshimoto M, Ge N, Flanagan L, de Silva HA, Kittel A Saitoh T (1995) The precursor protein of non-A beta component of Alzheimer's disease amyloid is a presynaptic protein of the central nervous system. Neuron 14, 467 475.
    • (1995) Neuron , vol.14 , pp. 467-475
    • Iwai, A.1    Masliah, E.2    Yoshimoto, M.3    Ge, N.4    Flanagan, L.5    De Silva, H.A.6    Kittel, A.7    Saitoh, T.8
  • 60
    • 33646364811 scopus 로고    scopus 로고
    • Cerebrolysin decreases amyloid- production by regulating amyloid protein precursor maturation in a transgenic model of Alzheimer's disease
    • DOI 10.1002/jnr.20818
    • Rockenstein E, Torrance M, Mante M, Adame A, Paulino A, Rose JB, Crews L, Moessler H Masliah E (2006) Cerebrolysin decreases amyloid-beta production by regulating amyloid protein precursor maturation in a transgenic model of Alzheimer's disease. J Neurosci Res 83, 1252 1261. (Pubitemid 43668008)
    • (2006) Journal of Neuroscience Research , vol.83 , Issue.7 , pp. 1252-1261
    • Rockenstein, E.1    Torrance, M.2    Mante, M.3    Adame, A.4    Paulino, A.5    Rose, J.B.6    Crews, L.7    Moessler, H.8    Masliah, E.9
  • 61
    • 0031787701 scopus 로고    scopus 로고
    • G protein subunits coimmunoprecipitated with antibodies against subunits: Identification of major isoforms in cultured cells by silver stain and immunoblotting with conventional transfer procedure
    • Ueda H, Morishita R, Katoh-Semba R, Kato K Asano T (1998) G protein gamma subunits coimmunoprecipitated with antibodies against alpha subunits: identification of major isoforms in cultured cells by silver stain and immunoblotting with conventional transfer procedure. J Biochem 124, 1033 1037. (Pubitemid 28544917)
    • (1998) Journal of Biochemistry , vol.124 , Issue.5 , pp. 1033-1037
    • Ueda, H.1    Morishita, R.2    Katoh-Semba, R.3    Kato, K.4    Asano, T.5


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