Heterotrimeric G-protein α-subunit adopts a "preactivated" conformation when associated with βγ-subunits

Journal of Biological Chemistry

Volumn 280, Issue 45, 2005, Pages 38071-38080

  Abdulaev, Najmoutin G ^a   Ngo, Tony ^a   Zhang, Cheng ^b   Dinh, Andy ^b   Brabazon, Danielle M ^c   Ridge, Kevin D ^b   Marino, John P ^a  

^a UNIVERSITY OF MARYLAND BIOTECHNOLOGY INSTITUTE   (United States)

^b UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

^c LOYOLA UNIVERSITY MARYLAND   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING ENERGY; CONCENTRATION (PROCESS); DRUG INTERACTIONS; FLUORESCENCE; NUCLEIC ACIDS; SIGNALING;

GDP/GTP EXCHANGE; HETEROTRIMERIC G-PROTEIN; RECEPTOR BINDING INTERFACE; STRUCTURAL CHANGES;

PROTEINS;

ALUMINUM FLUORIDE; G PROTEIN COUPLED RECEPTOR; GUANINE NUCLEOTIDE; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; GUANINE NUCLEOTIDE BINDING PROTEIN BETA SUBUNIT; GUANINE NUCLEOTIDE BINDING PROTEIN GAMMA SUBUNIT; GUANOSINE 5' O (3 THIOTRIPHOSPHATE); GUANOSINE DIPHOSPHATE; GUANOSINE TRIPHOSPHATE; MAGNESIUM ION; PROTEIN SUBUNIT; RHODOPSIN; TRYPTOPHAN;

ARTICLE; BINDING SITE; CARBOXY TERMINAL SEQUENCE; CATALYSIS; CHIMERA; CONCENTRATION (PARAMETERS); FLUORESCENCE; LIGHT; NITROGEN NUCLEAR MAGNETIC RESONANCE; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; PROTON NUCLEAR MAGNETIC RESONANCE; RECEPTOR BINDING; SIGNAL TRANSDUCTION; TITRIMETRY;

ESCHERICHIA COLI; GENE EXPRESSION; GTP-BINDING PROTEIN ALPHA SUBUNITS; GTP-BINDING PROTEIN BETA SUBUNITS; GTP-BINDING PROTEIN GAMMA SUBUNITS; MAGNESIUM; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; PROTEIN CONFORMATION;

EID: 27844496141     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M505259200     Document Type: Article

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