Oxidant stress-induced liver injury in vivo: Role of apoptosis, oncotic necrosis, and c-Jun NH2-terminal kinase activation

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 296, Issue 3, 2009, Pages

  Hong, Ji Young ^a   Lebofsky, Margitta ^a   Farhood, Anwar ^b   Jaeschke, Hartmut ^a  

^a UNIVERSITY OF KANSAS SCHOOL OF MEDICINE   (United States)

^b Brackenridge Hospital   (United States)

Author keywords

Caspases; Diquat; Endotoxin; Galactosamine; Mechanisms of cell death; Menadione; Superoxide

Indexed keywords

4 HYDROXYNONENAL; ALANINE AMINOTRANSFERASE; CASPASE 3; DIQUAT; DNA FRAGMENT; DNA NUCLEOTIDYLEXOTRANSFERASE; ENDOTOXIN; FERROUS SULFATE; GALACTOSAMINE; GLUTATHIONE DISULFIDE; MENADIONE; PHORONE; STRESS ACTIVATED PROTEIN KINASE; 4-HYDROXY-2-NONENAL; ALDEHYDE; ANTIFIBRINOLYTIC AGENT; CASPASE; SUPEROXIDE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL DEATH; CONTROLLED STUDY; DNA STRAND BREAKAGE; ENZYME ACTIVATION; ENZYME ACTIVITY; FEMALE; IN VIVO STUDY; LIVER INJURY; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; ANIMAL; BLOOD; CHEMICALLY INDUCED DISORDER; DISEASE MODEL; DNA FRAGMENTATION; FISCHER 344 RAT; LIVER CELL; LIVER DISEASE; MALE; METABOLISM; NECROSIS; NICK END LABELING; PATHOLOGY; PHYSIOLOGY;

ALANINE TRANSAMINASE; ALDEHYDES; ANIMALS; ANTIFIBRINOLYTIC AGENTS; APOPTOSIS; CASPASES; DIQUAT; DISEASE MODELS, ANIMAL; DNA FRAGMENTATION; ENDOTOXINS; GALACTOSAMINE; GLUTATHIONE DISULFIDE; HEPATOCYTES; IN SITU NICK-END LABELING; JNK MITOGEN-ACTIVATED PROTEIN KINASES; LIVER DISEASES; MALE; NECROSIS; OXIDATIVE STRESS; RATS; RATS, INBRED F344; SUPEROXIDES; VITAMIN K 3;

EID: 65349122497     PISSN: 01931857     EISSN: 15221547     Source Type: Journal    
DOI: 10.1152/ajpgi.90435.2008     Document Type: Article

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