Superoxide anions and hydrogen peroxide induce hepatocyte death by different mechanisms: Involvement of JNK and ERK MAP kinases

Journal of Hepatology

Volumn 44, Issue 5, 2006, Pages 918-929

  Conde de la Rosa, Laura ^a   Schoemaker, Marieke H ^a   Vrenken, Titia E ^a   Buist Homan, Manon ^a   Havinga, Rick ^a   Jansen, Peter L M ^b   Moshage, Han ^a  

^a UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^b ACADEMIC MEDICAL CENTER   (Netherlands)

Author keywords

Apoptosis; Caspase; Glutathione.; Necrosis; Oxidative stress; Signal transduction

Indexed keywords

CASPASE; CASPASE 3; CASPASE 6; CASPASE 9; GLUTATHIONE; HYDROGEN PEROXIDE; MENADIONE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; NITRIC OXIDE DONOR; REACTIVE OXYGEN METABOLITE; SNARE PROTEIN; STRESS ACTIVATED PROTEIN KINASE; SUPEROXIDE; SUPEROXIDE DISMUTASE MACROGOL;

ANIMAL CELL; APOPTOSIS; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; EXPOSURE; LIVER CELL CULTURE; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; RAT; STAINING;

ANIMALS; APOPTOSIS; CASPASES; CELLS, CULTURED; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FREE RADICAL SCAVENGERS; GLUTATHIONE; HEPATOCYTES; HYDROGEN PEROXIDE; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MALE; MAP KINASE SIGNALING SYSTEM; NECROSIS; NF-KAPPA B; OXIDANTS; OXIDATIVE STRESS; RATS; RATS, WISTAR; REACTIVE OXYGEN SPECIES; SPECIFIC PATHOGEN-FREE ORGANISMS; SUPEROXIDES; VITAMIN K 3; VITAMINS;

EID: 33645771481     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jhep.2005.07.034     Document Type: Article

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