-
1
-
-
0030234981
-
Targetable drug carriers: Present status and a future perspective
-
M Yokoyama T Okano 1996 Targetable drug carriers: present status and a future perspective Adv Drug Deliv Rev 21 77 80
-
(1996)
Adv Drug Deliv Rev
, vol.21
, pp. 77-80
-
-
Yokoyama, M.1
Okano, T.2
-
2
-
-
0030175405
-
Importance of pharmacokinetic considerations in the development of drug delivery systems
-
Y Sugiyama 1996 Importance of pharmacokinetic considerations in the development of drug delivery systems Adv Drug Deliv Rev 19 333 334
-
(1996)
Adv Drug Deliv Rev
, vol.19
, pp. 333-334
-
-
Sugiyama, Y.1
-
4
-
-
0022858683
-
A new concept for macromolecular therapeutics in cancer chemotherapy: Mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs
-
Y Matsumura H Maeda 1986 A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs Cancer Res 46 6387 6392
-
(1986)
Cancer Res
, vol.46
, pp. 6387-6392
-
-
Matsumura, Y.1
Maeda, H.2
-
5
-
-
0034993240
-
The enhanced permeability and retention (EPR) effect in tumor vasculature: The key role of tumor-selective macromolecular drug targeting
-
H Maeda 2001 The enhanced permeability and retention (EPR) effect in tumor vasculature: the key role of tumor-selective macromolecular drug targeting Adv Enzyme Regul 41 189 207
-
(2001)
Adv Enzyme Regul
, vol.41
, pp. 189-207
-
-
Maeda, H.1
-
6
-
-
0028055226
-
Effect of liposome size on the circulation time and intraorgan distribution of amphipathic poly(ethylene glycol)-containing liposomes
-
DC Litzinger AMJ Buiting N van Rooijen L Huang 1994 Effect of liposome size on the circulation time and intraorgan distribution of amphipathic poly(ethylene glycol)-containing liposomes Biochim Biophys Acta 1190 99 107
-
(1994)
Biochim Biophys Acta
, vol.1190
, pp. 99-107
-
-
Litzinger, D.C.1
Buiting, A.M.J.2
Van Rooijen, N.3
Huang, L.4
-
9
-
-
0027218284
-
Cure of xenografted human carcinomas by BR-96-doxorubicin immunoconjugates
-
PA Trail D Willner SJ Lasch AJ Henderson S Hofstead AM Casazza RA Firestone KE Hellstrom 1993 Cure of xenografted human carcinomas by BR-96-doxorubicin immunoconjugates Science 261 212 215
-
(1993)
Science
, vol.261
, pp. 212-215
-
-
Trail, P.A.1
Willner, D.2
Lasch, S.J.3
Henderson, A.J.4
Hofstead, S.5
Casazza, A.M.6
Firestone, R.A.7
Hellstrom, K.E.8
-
10
-
-
0346551010
-
Polymer conjugates with anticancer activity
-
D Putnam J Kopecek 1995 Polymer conjugates with anticancer activity Adv Polymer Sci 122 55 123
-
(1995)
Adv Polymer Sci
, vol.122
, pp. 55-123
-
-
Putnam, D.1
Kopecek, J.2
-
11
-
-
0030484881
-
The role of polymer conjugates in the diagnosis and treatment of cancer
-
R Duncan S Dimitrijevic EG Evagorou 1996 The role of polymer conjugates in the diagnosis and treatment of cancer STP Pharma Sci 6 237 263
-
(1996)
STP Pharma Sci
, vol.6
, pp. 237-263
-
-
Duncan, R.1
Dimitrijevic, S.2
Evagorou, E.G.3
-
13
-
-
0023102353
-
Soluble, crosslinked N-(2-hydroxypropyl) methacrylamide copolymers as potential drug carriers. 2: Effect of molecular weight on blood clearance and body distribution in the rat after intravenous administration. Distribution of unfractionated copolymer after intraperitoneal, subcutaneous or oral administration
-
SA Cartlidge R Duncan JB Lloyd PK Rejmanova J Kopecek 1987 Soluble, crosslinked N-(2-hydroxypropyl) methacrylamide copolymers as potential drug carriers. 2: Effect of molecular weight on blood clearance and body distribution in the rat after intravenous administration. Distribution of unfractionated copolymer after intraperitoneal, subcutaneous or oral administration J Contr Rel 4 253 264
-
(1987)
J Contr Rel
, vol.4
, pp. 253-264
-
-
Cartlidge, S.A.1
Duncan, R.2
Lloyd, J.B.3
Rejmanova, P.K.4
Kopecek, J.5
-
14
-
-
0023450012
-
Effect of molecular weight of N-(2-hydroxypropyl)methacrylamide copolymers on body distribution and rate of excretion after subcutaneous, intraperitoneal, and intravenous administration to rats
-
LW Seymour R Duncan J Strohalm J Kopecek 1987 Effect of molecular weight of N-(2-hydroxypropyl)methacrylamide copolymers on body distribution and rate of excretion after subcutaneous, intraperitoneal, and intravenous administration to rats J Biomed Mater Res 21 1341 1358
-
(1987)
J Biomed Mater Res
, vol.21
, pp. 1341-1358
-
-
Seymour, L.W.1
Duncan, R.2
Strohalm, J.3
Kopecek, J.4
-
15
-
-
0026561607
-
Preclinical evaluation of polymer-bound doxorubicin
-
R Duncan LW Seymour KB O'Hare PA Flanagan S Wedge IC Hume K Ulbrich J Strohalm V Subr F Spreafico M Grandi M Ripamonti M Farao A Suarato 1992 Preclinical evaluation of polymer-bound doxorubicin J Contr Rel 19 331 346
-
(1992)
J Contr Rel
, vol.19
, pp. 331-346
-
-
Duncan, R.1
Seymour, L.W.2
O'Hare, K.B.3
Flanagan, P.A.4
Wedge, S.5
Hume, I.C.6
Ulbrich, K.7
Strohalm, J.8
Subr, V.9
Spreafico, F.10
Grandi, M.11
Ripamonti, M.12
Farao, M.13
Suarato, A.14
-
16
-
-
0026512810
-
Evaluation of protein-N-(2-hydroxypropyl) methacrylamide copolymer conjugates as targetable drug carriers. 2. Body distribution of conjugates containing transferrin, anti-transferrin receptor antibody or anti-Thy 1.2 antibody and effectiveness of transferrin-containing daunomycin conjugates against mouse L 1210 leukaemia in vivo
-
PA Flanagan R Duncan V Subr K Ulbrich P Kopecekova J Kopecek 1992 Evaluation of protein-N-(2-hydroxypropyl) methacrylamide copolymer conjugates as targetable drug carriers. 2. Body distribution of conjugates containing transferrin, anti-transferrin receptor antibody or anti-Thy 1.2 antibody and effectiveness of transferrin-containing daunomycin conjugates against mouse L 1210 leukaemia in vivo J Contr Rel 18 25 38
-
(1992)
J Contr Rel
, vol.18
, pp. 25-38
-
-
Flanagan, P.A.1
Duncan, R.2
Subr, V.3
Ulbrich, K.4
Kopecekova, P.5
Kopecek, J.6
-
17
-
-
0025855856
-
Comparison of the liver subcelluar distribution of free daunomycin and that bound to galactosamine targeted N-(2-hydroxypropyl)methacrylamide copolymers, following intravenous administration in the rat
-
SR Wedge R Duncan P Kopeckova 1991 Comparison of the liver subcelluar distribution of free daunomycin and that bound to galactosamine targeted N-(2-hydroxypropyl)methacrylamide copolymers, following intravenous administration in the rat Br J Cancer 63 546 549
-
(1991)
Br J Cancer
, vol.63
, pp. 546-549
-
-
Wedge, S.R.1
Duncan, R.2
Kopeckova, P.3
-
18
-
-
0023140149
-
A multicenter double-blind controlled study of lipo-PGE1, PGE1 incorporated in lipid microspheres, in peripheral vascular disease secondary to connective tissue disorders
-
Y Mizushima Y Shiokawa S Kashiwazaki Y Ichikawa H Hashimoto A Sakuma 1987 A multicenter double-blind controlled study of lipo-PGE1, PGE1 incorporated in lipid microspheres, in peripheral vascular disease secondary to connective tissue disorders J Rheumatol 14 97 101
-
(1987)
J Rheumatol
, vol.14
, pp. 97-101
-
-
Mizushima, Y.1
Shiokawa, Y.2
Kashiwazaki, S.3
Ichikawa, Y.4
Hashimoto, H.5
Sakuma, A.6
-
19
-
-
0023659741
-
Large unilamellar liposomes with low uptake into the reticuloendothelial system
-
TM Allen A Chonn 1987 Large unilamellar liposomes with low uptake into the reticuloendothelial system FEBS Lett 223 42 46
-
(1987)
FEBS Lett
, vol.223
, pp. 42-46
-
-
Allen, T.M.1
Chonn, A.2
-
21
-
-
0029038996
-
Liposomal doxorubicin: Antitumor activity and unique toxicities during two complementary phase I studies
-
B Uriely S Jeffers R Isacson K Kutsch D Wei-Tsao Z Yehoshua E Libson FM Muggia S Gabizon 1995 Liposomal doxorubicin: antitumor activity and unique toxicities during two complementary phase I studies J Clin Oncol 13 1777 1785
-
(1995)
J Clin Oncol
, vol.13
, pp. 1777-1785
-
-
Uriely, B.1
Jeffers, S.2
Isacson, R.3
Kutsch, K.4
Wei-Tsao, D.5
Yehoshua, Z.6
Libson, E.7
Muggia, F.M.8
Gabizon, S.9
-
22
-
-
84981904448
-
Watersoluble polymers in medicine
-
H Bader H Ringsdorf 1984 Watersoluble polymers in medicine Angew Makromol Chem 123/124 457 485
-
(1984)
Angew Makromol Chem
, vol.123-124
, pp. 457-485
-
-
Bader, H.1
Ringsdorf, H.2
-
24
-
-
0342972939
-
Site-specific drug delivery using polymeric carriers
-
Gordon and Breach Yverdon, Switzerland
-
M Yokoyama 1994 Site-specific drug delivery using polymeric carriers Advances in polymeric systems for drug delivery Gordon and Breach Yverdon, Switzerland 24 66
-
(1994)
Advances in Polymeric Systems for Drug Delivery
, pp. 24-66
-
-
Yokoyama, M.1
-
26
-
-
0037148656
-
Poly(ethylene oxide)-block-poly(l-amino acid) micelles for drug delivery
-
A Lavasanifar J Samuel GS Kwon 2002 Poly(ethylene oxide)-block-poly(l- amino acid) micelles for drug delivery Adv Drug Deliv Rev 54 169 190
-
(2002)
Adv Drug Deliv Rev
, vol.54
, pp. 169-190
-
-
Lavasanifar, A.1
Samuel, J.2
Kwon, G.S.3
-
27
-
-
49549135578
-
Block and graft copolymer micelles in solution
-
Z Tuzar P Kratochvil 1976 Block and graft copolymer micelles in solution Adv Colloid Interfac Sci 6 201 232
-
(1976)
Adv Colloid Interfac Sci
, vol.6
, pp. 201-232
-
-
Tuzar, Z.1
Kratochvil, P.2
-
28
-
-
0024351519
-
The neuroleptic activity of haloperidol increases after its solubilization in surfactant micelles: Micelles as microcontainers for drug targeting
-
AV Kabanov VP Chekhonin VY Alakhov EV Batrakova AS Lebedev NS Melik-Nubarov SA Arzhakov AV Levashov GV Morozov ES Severin VA Kabanov 1989 The neuroleptic activity of haloperidol increases after its solubilization in surfactant micelles: micelles as microcontainers for drug targeting FEBS Lett 258 343 345
-
(1989)
FEBS Lett
, vol.258
, pp. 343-345
-
-
Kabanov, A.V.1
Chekhonin, V.P.2
Alakhov, V.Y.3
Batrakova, E.V.4
Lebedev, A.S.5
Melik-Nubarov, N.S.6
Arzhakov, S.A.7
Levashov, A.V.8
Morozov, G.V.9
Severin, E.S.10
Kabanov, V.A.11
-
29
-
-
0037133113
-
The effect of fatty acid substitution on the in vitro release of amphotericin B from micelles composed of poly(ethylene oxide)-block-poly(N-hexyl stearate-l-aspartamide
-
A Lavasanifar J Samuel GS Kwon 2002 The effect of fatty acid substitution on the in vitro release of amphotericin B from micelles composed of poly(ethylene oxide)-block-poly(N-hexyl stearate-l-aspartamide J Controlled Release 79 165 172
-
(2002)
J Controlled Release
, vol.79
, pp. 165-172
-
-
Lavasanifar, A.1
Samuel, J.2
Kwon, G.S.3
-
30
-
-
0033991545
-
Polycaprolactone-b-poly(ethylene oxide) copolymer micelles as a delivery vehicle for dihydrotestosterone
-
C Allen J Han Y Yu D Maysinger A Eisenberg 2000 Polycaprolactone-b- poly(ethylene oxide) copolymer micelles as a delivery vehicle for dihydrotestosterone J Controlled Release 51 275 286
-
(2000)
J Controlled Release
, vol.51
, pp. 275-286
-
-
Allen, C.1
Han, J.2
Yu, Y.3
Maysinger, D.4
Eisenberg, A.5
-
31
-
-
0027112202
-
New macromolecular carriers for drugs. I. Preparation and characterization of poly(oxyethylene-b-isoprene-b-oxyethylene) block copolymer aggregates
-
A Rolland J O'Mullane P Goddard L Brookman K Petrak 1992 New macromolecular carriers for drugs. I. Preparation and characterization of poly(oxyethylene-b-isoprene-b-oxyethylene) block copolymer aggregates J Appl Polym Sci 44 1195 1203
-
(1992)
J Appl Polym Sci
, vol.44
, pp. 1195-1203
-
-
Rolland, A.1
O'Mullane, J.2
Goddard, P.3
Brookman, L.4
Petrak, K.5
-
32
-
-
0033064658
-
Micellar delivery of doxorubicin and its paramagnetic analog, ruboxyl, to HL-60 cells: Effect of micelle structure and ultrasound on the intracellular drug uptake
-
NY Rapoport JN Herron WG Pitt L Pitina 1999 Micellar delivery of doxorubicin and its paramagnetic analog, ruboxyl, to HL-60 cells: effect of micelle structure and ultrasound on the intracellular drug uptake J Controlled Release 58 153 162
-
(1999)
J Controlled Release
, vol.58
, pp. 153-162
-
-
Rapoport, N.Y.1
Herron, J.N.2
Pitt, W.G.3
Pitina, L.4
-
33
-
-
0030385934
-
Spontaneous formation of polyion complex micelles with narrow distribution from antisense oligonucleotide and cationic block copolymer in physiological saline
-
K Kataoka H Togawa A Harada K Yasugi T Matsumoto S Katayose 1996 Spontaneous formation of polyion complex micelles with narrow distribution from antisense oligonucleotide and cationic block copolymer in physiological saline Macromolecules 29 8556 8557
-
(1996)
Macromolecules
, vol.29
, pp. 8556-8557
-
-
Kataoka, K.1
Togawa, H.2
Harada, A.3
Yasugi, K.4
Matsumoto, T.5
Katayose, S.6
-
34
-
-
0001252124
-
Molecular design for missile drug: Synthesis of adriamycin conjugated with IgG using poly(ethylene glycol)-poly(aspartic acid) block copolymer as intermediate carrier
-
M Yokoyama S Inoue K Kataoka N Yui Y Sakurai 1989 Molecular design for missile drug: synthesis of adriamycin conjugated with IgG using poly(ethylene glycol)-poly(aspartic acid) block copolymer as intermediate carrier Makromol Chem 190 2041 2054
-
(1989)
Makromol Chem
, vol.190
, pp. 2041-2054
-
-
Yokoyama, M.1
Inoue, S.2
Kataoka, K.3
Yui, N.4
Sakurai, Y.5
-
35
-
-
0025343062
-
Characterization and anti-cancer activity of micelle-forming polymeric anti-cancer drug, adriamycin-conjugated poly(ethylene glycol)-poly(aspartic acid) block copolymer
-
M Yokoyama M Miyauchi N Yamada T Okano Y Sakurai K Kataoka S Inoue 1990 Characterization and anti-cancer activity of micelle-forming polymeric anti-cancer drug, adriamycin-conjugated poly(ethylene glycol)-poly(aspartic acid) block copolymer Cancer Res 50 1693 1700
-
(1990)
Cancer Res
, vol.50
, pp. 1693-1700
-
-
Yokoyama, M.1
Miyauchi, M.2
Yamada, N.3
Okano, T.4
Sakurai, Y.5
Kataoka, K.6
Inoue, S.7
-
36
-
-
0025874282
-
Toxicity and antitumor activity against solid tumors of micelle-forming polymeric drug and its extremely long circulation in blood
-
M Yokoyama N Yamada T Okano Y Sakurai K Kataoka S Inoue 1991 Toxicity and antitumor activity against solid tumors of micelle-forming polymeric drug and its extremely long circulation in blood Cancer Res 51 3229 3236
-
(1991)
Cancer Res
, vol.51
, pp. 3229-3236
-
-
Yokoyama, M.1
Yamada, N.2
Okano, T.3
Sakurai, Y.4
Kataoka, K.5
Inoue, S.6
-
37
-
-
0028346185
-
Enhanced tumor accumulation and prolonged circulation times of micelle-forming poly(ethylene oxide-aspartate) block copolymer-adriamycin conjugates
-
GS Kwon S Suwa M Yokoyama T Okano Y Sakurai K Kataoka 1994 Enhanced tumor accumulation and prolonged circulation times of micelle-forming poly(ethylene oxide-aspartate) block copolymer-adriamycin conjugates J Controlled Release 29 17 23
-
(1994)
J Controlled Release
, vol.29
, pp. 17-23
-
-
Kwon, G.S.1
Suwa, S.2
Yokoyama, M.3
Okano, T.4
Sakurai, Y.5
Kataoka, K.6
-
40
-
-
0023141221
-
Anticancer agents coupled to N-(2-hydroxypropyl)methacrylamide copolymers I. Evaluation of daunomycin and puromycin conjugates in vitro
-
R Duncan P Kopeckova-Rejmanova J Strohalm I Hume HC Cable J Pohl JB Lloyd J Kopecek 1987 Anticancer agents coupled to N-(2-hydroxypropyl)methacrylamide copolymers I. Evaluation of daunomycin and puromycin conjugates in vitro Br J Cancer 55 165 174
-
(1987)
Br J Cancer
, vol.55
, pp. 165-174
-
-
Duncan, R.1
Kopeckova-Rejmanova, P.2
Strohalm, J.3
Hume, I.4
Cable, H.C.5
Pohl, J.6
Lloyd, J.B.7
Kopecek, J.8
-
41
-
-
0023618409
-
A novel covalent modification of antibodies at their amino groups with retention of antigen-binding activity
-
N Endo N Umemoto Y Kato Y Takeda T Hara 1987 A novel covalent modification of antibodies at their amino groups with retention of antigen-binding activity J Immunol Methods 104 253 258
-
(1987)
J Immunol Methods
, vol.104
, pp. 253-258
-
-
Endo, N.1
Umemoto, N.2
Kato, Y.3
Takeda, Y.4
Hara, T.5
-
42
-
-
0024438996
-
Poly(carboxylic acid) polymers as carriers for anthracyclines
-
F Zunino G Pratesi A Micheloni 1989 Poly(carboxylic acid) polymers as carriers for anthracyclines J Controlled Release 10 65 73
-
(1989)
J Controlled Release
, vol.10
, pp. 65-73
-
-
Zunino, F.1
Pratesi, G.2
Micheloni, A.3
-
44
-
-
4644316820
-
Polymer design and incorporation method for polymeric micelle carrier system containing water-insoluble anti-cancer agent camptothecin
-
M Yokoyama P Opanasopit Y Maitani K Kawano T Okano 2004 Polymer design and incorporation method for polymeric micelle carrier system containing water-insoluble anti-cancer agent camptothecin J Drug Targeting 12 373 384
-
(2004)
J Drug Targeting
, vol.12
, pp. 373-384
-
-
Yokoyama, M.1
Opanasopit, P.2
Maitani, Y.3
Kawano, K.4
Okano, T.5
-
45
-
-
19444372638
-
Block copolymer design for camptothecin incorporation into polymeric micelles for passive tumor targeting
-
P Opanasopit M Yokoyama M Watanabe K Kawano Y Maitani T Okano 2004 Block copolymer design for camptothecin incorporation into polymeric micelles for passive tumor targeting Pharm Res 21 2003 2010
-
(2004)
Pharm Res
, vol.21
, pp. 2003-2010
-
-
Opanasopit, P.1
Yokoyama, M.2
Watanabe, M.3
Kawano, K.4
Maitani, Y.5
Okano, T.6
-
47
-
-
20944450473
-
NK105, a paclitaxel-incorporating micellar nanoparticle formulation, can extend the therapeutic window of the drug
-
T Hamaguchi Y Matsumura M Suzuki K Shimizu R Goda I Nakamura I Nakatomi M Yokoyama K Kataoka J Kakizoe 2005 NK105, a paclitaxel-incorporating micellar nanoparticle formulation, can extend the therapeutic window of the drug British J Cancer 92 1240 1246
-
(2005)
British J Cancer
, vol.92
, pp. 1240-1246
-
-
Hamaguchi, T.1
Matsumura, Y.2
Suzuki, M.3
Shimizu, K.4
Goda, R.5
Nakamura, I.6
Nakatomi, I.7
Yokoyama, M.8
Kataoka, K.9
Kakizoe, J.10
|