Phosphorylcholine-polycation diblock copolymers as synthetic vectors for gene delivery

Journal of Controlled Release

Volumn 100, Issue 2, 2004, Pages 293-312

  Lam, J K W ^a   Ma, Y ^b   Armes, S P ^b   Lewis, A L ^c   Baldwin, T ^a   Stolnik, S ^a  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^b UNIVERSITY OF SUSSEX   (United Kingdom)

^c BIOCOMPATIBLES UK LTD   (United Kingdom)

Author keywords

Non viral gene delivery; Polyelectrolyte complexes; Steric stabilization; Transfection

Indexed keywords

DIBLOCK COPOLYMER; PHOSPHORYCHOLINE (PC); STERIC STABILIZER;

BIOLOGICAL MEMBRANES; COMPOSITION; DNA; GENES; SYNTHESIS (CHEMICAL);

COPOLYMERS;

2 (METHACRYLOXYETHYLPHOSPHORYLCHOLINE); COPOLYMER; LUCIFERASE; METHACRYLIC ACID DERIVATIVE; METHACRYLIC ACID DIMETHYLAMINOETHYL ESTER; PHOSPHORYLCHOLINE; PLASMID DNA; POLYCATION; UNCLASSIFIED DRUG;

ARTICLE; BIOCOMPATIBILITY; CONTROLLED STUDY; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; NONVIRAL GENE DELIVERY SYSTEM; PHYSICAL CHEMISTRY; POLYMERIZATION; PRIORITY JOURNAL;

BUFFERS; CATIONS; CELL LINE, TUMOR; DRUG DELIVERY SYSTEMS; ELECTROPHORESIS, AGAR GEL; ETHIDIUM; FLOW CYTOMETRY; FLUORESCENT DYES; GENE THERAPY; HUMANS; INDICATORS AND REAGENTS; LUCIFERASES; METHACRYLATES; MICROSCOPY, ELECTRON, TRANSMISSION; PARTICLE SIZE; PHOSPHORYLCHOLINE; PLASMIDS; POLYMERS; TRANSFECTION;

EID: 8544261100     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2004.08.028     Document Type: Article

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