ATP-phosphopeptide conjugates as inhibitors of Src tyrosine kinases

Bioorganic and Medicinal Chemistry

Volumn 12, Issue 22, 2004, Pages 5753-5766

  Nam, Nguyen Hai ^a   Lee, Sungsoo ^b   Ye, Guofeng ^a   Sun, Gongqin ^b   Parang, Keykavous ^a  

^a UNIVERSITY OF RHODE ISLAND   (United States)

^b UNIVERSITY OF RHODE ISLAND   (United States)

Author keywords

Inhibitors; pYEEI; Src SH2 domain; Src tyrosine kinases

Indexed keywords

ADENOSINE TRIPHOSPHATE DERIVATIVE; PHOSPHOPEPTIDE; PROTEIN SH2; PROTEIN TYROSINE KINASE INHIBITOR; TETRAPEPTIDE; TYROSYLGLUTAMYLGLUTAMYLISOLEUCINE; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; DRUG ACTIVITY; DRUG CONJUGATION; DRUG DESIGN; DRUG DETERMINATION; DRUG MECHANISM; DRUG PROTEIN BINDING; DRUG SYNTHESIS; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; ENZYME SUBSTRATE; PHARMACOLOGICAL BLOCKING; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; STRUCTURE ACTIVITY RELATION;

ADENOSINE TRIPHOSPHATE; BINDING SITES; PHOSPHOPEPTIDES; PROTEIN KINASE INHIBITORS; SRC-FAMILY KINASES;

EID: 6344236775     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2004.08.043     Document Type: Article

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