High-affinity Src-SH2 ligands which do not activate Tyr527-phosphorylated Src in an experimental in vivo system

Biochemical and Biophysical Research Communications

Volumn 298, Issue 2, 2002, Pages 185-192

  Mandine, Eliane ^a   Jean Baptiste, Véronique ^a   Vayssière, Béatrice ^b   Gofflo, Dominique ^a   Bénard, Didier ^c   Sarubbi, Edoardo ^d   Deprez, Pierre ^c   Baron, Roland ^a   Superti Furga, Giulio ^e   Lesuisse, Dominique ^c  

^a Bone Diseases Group   (France)

^b INSTITUT CURIE   (France)

^c Medicinal Chemistry   (France)

^d Protein Production   (France)

^e EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

Author keywords

Csk inactivated Src; SH2 domains; SH2 inhibitors; Src kinase; Src reactivation

Indexed keywords

LIGAND; PEPTIDE HORMONE; PROTEIN TYROSINE KINASE; TYROSINE;

ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; ENZYME ACTIVATION; ENZYME ANALYSIS; ENZYME LINKED IMMUNOSORBENT ASSAY; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; ONCOGENE SRC; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN; SCHIZOSACCHAROMYCES POMBE; SIGNAL TRANSDUCTION; TARGET CELL;

ANIMALS; ENZYME ACTIVATION; ENZYME INHIBITORS; ENZYME-LINKED IMMUNOSORBENT ASSAY; HUMANS; LIGANDS; PEPTIDES; PHOSPHORYLATION; PROTEIN-TYROSINE KINASES; RATS; SCHIZOSACCHAROMYCES; SRC HOMOLOGY DOMAINS; SRC-FAMILY KINASES; TRANSFORMATION, GENETIC; TYROSINE;

SCHIZOSACCHAROMYCES; SCHIZOSACCHAROMYCES POMBE;

EID: 0036408418     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-291X(02)02424-5     Document Type: Article

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