Neurotrophins in cell survival/death decisions

Advances in Experimental Medicine and Biology

Volumn 468, Issue , 2000, Pages 275-282

  Casaccia Bonnefil, P ^a   Gu, C ^a   Chao, M V ^a  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BONE MORPHOGENETIC PROTEIN; BRAIN DERIVED NEUROTROPHIC FACTOR; CASPASE; CYTOKINE; CYTOKINE RECEPTOR; FAS ANTIGEN; NERVE GROWTH FACTOR; NEUROTROPHIN; NEUROTROPHIN 3; NEUROTROPHIN 4; NEUROTROPHIN 6; NEUROTROPHIN RECEPTOR; PROTEIN P75; PROTEIN TYROSINE KINASE; TUMOR NECROSIS FACTOR; TUMOR NECROSIS FACTOR RECEPTOR;

CELL DEATH; CELL DIFFERENTIATION; CELL POPULATION; CELL SURVIVAL; CELL VIABILITY; CONFERENCE PAPER; DEGENERATIVE DISEASE; ENZYME ACTIVATION; GLIA CELL; OLIGODENDROGLIA; PRIORITY JOURNAL; PROTEIN STRUCTURE; RECEPTOR BINDING; SECOND MESSENGER; SIGNAL TRANSDUCTION; STEM CELL;

ANIMALS; CELL DEATH; CELL DIFFERENTIATION; CELL SURVIVAL; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MITOGEN-ACTIVATED PROTEIN KINASES; NERVE GROWTH FACTORS; NEURONS; OLIGODENDROGLIA; RATS; RECEPTORS, NERVE GROWTH FACTOR; SIGNAL TRANSDUCTION;

EID: 0034465729     PISSN: 00652598     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (41)

1. The trk family of neurotrophin receptors
2. Neurotrophin-5: A novel neurotrophic factor that activates Trk and TrkB
3. Neurotrophin-5: A novel neurotrophic factor that activates Trk and TrkB
4. Selective activation of NK-kB by nerve growth factor through the neurotrophin receptor p75
5. Death of oligodendrocytes mediated by the interaction of nerve growth factor with its receptor p75
6. Neurotrophin receptors: A window into neuronal differentiation
7. Sphingosine-1-phosphate inhibits ceramide mediated programmed cell death
8. TrkB signalling inhibits p75-mediated apoptosis induced by nerve growth factor in embryonic proprioceptive neurons
9. p75 deficient trigeminal sensory neurons have an altered response to NGF but not to other neurotrophins
10. Activation of the sphingomyelin cycle through the low-affinity neurotrophin receptor
11. Neurotrophins induce sphingomyelin hydrolysis
12. Regulation of neuronal survival by the serine-threonine kinase Akt
13. Involvement of sphingosine 1-phosphate in nerve growth factor-mediated neuronal survival and differentiation
14. The death domain: A module shared by proteins with diverse cellular functions
15. Induction of cell death by endogenous nerve growth factor through its p75 receptor
16. Microglia-derived nerve growth factor causes cell death in the developing retina
17. The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase
18. Direct regulation of the Akt proto-oncogene product by phosphatidylinositol-3.4-biphosphate
19. The death domain motif found in Fas (Apo-1) and TNF receptor is present in proteins involved in apoptosis and axonal guidance
20. Similarities and differences in the way neurotrophins interact with the trk receptors in neuronal and nonneuronal cells
21. The trkB tyrosine protein-kinase is a receptor for neurotrophin-4
22. A lipid-anchored Grb2-binding protein that links FGF-receptor activation to the Ras/MAPK signaling pathway
23. trkC, a new member of the trk family of tyrosine protein kinases, is a receptor for neurotrophin-3
24. p75-deficient embryonic dorsal root sensory and neonatal sympathetic neurons display a decreased sensitivity to NGF
25. NMR structure of the death domain of the p75 neurotrophin receptor
26. A new protein fold revealed by a 2.3A resolution crystal structure of nerve growth factor
27. A new structural superfamily of growth factors defined by a cystine knot motif
28. N-shc: A neuronal specific adapter molecule that mediates signaling from neurotrophin/Trk to ras/MAPk pathway
29. Identification of Trk binding sites for SHC and PI-3′-kinase and formation of a multimeric signaling complex
30. Activation of phosphatidylinositol-3 kinase by nerve growth factor involes indirect coupling of the trk proto-oncogene with src homology 2 domain
31. Sphingosine-1-phosphate as second messenger in cell proliferation induced by PDGF and FCS mitogens
32. Signalling through scaffold, anchoring, and adaptor proteins
33. Intracellular signaling pathways activated by neurotrophic factors
34. The TNF receptor superfamily of cellular and viral proteins: Activation, costimulation, and death
35. Trk receptors use redundant signal-transduction pathways involving SHC and PLC-gamma-1 to mediate NGF responses
36. Requirement for ceramide-initiated SAPK/JNK signalling in stress-induced apoptosis
37. Broadly expressed SNT-like proteins link FGF receptor stimulation to activators of Ras
38. Ceramide activates stress-activated protein kinases
39. Ras mediates NGF receptor modulation of three signal-transducing protein kinases: MAP kinase, raf-1, and RSK
40. Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis induced by neurotrophic factor withdrawal
41. Competitive signaling between TrkA and p75 nerve growth factor receptors determines cell survival