Design of tetrapeptide ligands as inhibitors of the Src SH2 domain

Bioorganic and Medicinal Chemistry

Volumn 12, Issue 4, 2004, Pages 779-787

  Nam, Nguyen Hai ^a   Pitts, Rebecca L ^a   Sun, Gongqin ^a   Sardari, Soroush ^a   Tiemo, Amie ^a   Xie, Mingxing ^a   Yan, Bingfang ^a   Parang, Keykavous ^a  

^a UNIVERSITY OF RHODE ISLAND   (United States)

Author keywords

Fluorescence polarization; pYEEI; Src SH2 domain; Tetrapeptides

Indexed keywords

BENZENE DERIVATIVE; PHENYLALANINE DERIVATIVE; PHOSPHOTYROSYLGLUTAMYLGLUTAMYLISOLEUCINE; PROTEIN INHIBITOR; PROTEIN SH2; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; ANTIFUNGAL ACTIVITY; ARTICLE; BINDING AFFINITY; CANCER CELL CULTURE; CANCER GROWTH; CANDIDA ALBICANS; CARBOXY TERMINAL SEQUENCE; CELL PROLIFERATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CORRELATION ANALYSIS; DRUG ACTIVITY; DRUG PROTEIN BINDING; DRUG SYNTHESIS; EMBRYO CELL; FLUORESCENCE POLARIZATION; IC 50; KIDNEY CELL; NONHUMAN; PEPTIDE SYNTHESIS; STRUCTURE ACTIVITY RELATION;

CANDIDA ALBICANS;

EID: 0842305206     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2003.10.060     Document Type: Article

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