-
1
-
-
0035668921
-
Structural biology of human follitropin and its receptor
-
Dias J.A., Van Roey P. Structural biology of human follitropin and its receptor. Arch. Med. Res. 32:2001;510-519.
-
(2001)
Arch. Med. Res.
, vol.32
, pp. 510-519
-
-
Dias, J.A.1
Van Roey, P.2
-
2
-
-
0036083401
-
Thyroid-stimulating hormone and thyroid-stimulating hormone receptor structure-function relationships
-
Szkudlinski M.W., et al. Thyroid-stimulating hormone and thyroid-stimulating hormone receptor structure-function relationships. Physiol. Rev. 82:2002;473-502.
-
(2002)
Physiol. Rev.
, vol.82
, pp. 473-502
-
-
Szkudlinski, M.W.1
-
3
-
-
0036217072
-
The lutropin/choriogonadotropin receptor, a 2002 perspective
-
Ascoli M., et al. The lutropin/choriogonadotropin receptor, a 2002 perspective. Endocr. Rev. 23:2002;141-174.
-
(2002)
Endocr. Rev.
, vol.23
, pp. 141-174
-
-
Ascoli, M.1
-
4
-
-
0025847496
-
Amino-terminal leucine-rich repeats in gonadotropin receptors determine hormone selectivity
-
Braun T., et al. Amino-terminal leucine-rich repeats in gonadotropin receptors determine hormone selectivity. EMBO J. 10:1991;1885-1890.
-
(1991)
EMBO J.
, vol.10
, pp. 1885-1890
-
-
Braun, T.1
-
5
-
-
0025567011
-
Extracellular domain chimeras of the TSH and LHCG receptors reveal the mid-region (amino acids 171-260) to play a vital role in high affinity TSH binding
-
Nagayama Y., et al. Extracellular domain chimeras of the TSH and LHCG receptors reveal the mid-region (amino acids 171-260) to play a vital role in high affinity TSH binding. Biochem. Biophys. Res. Commun. 173:1990;1150-1156.
-
(1990)
Biochem. Biophys. Res. Commun.
, vol.173
, pp. 1150-1156
-
-
Nagayama, Y.1
-
6
-
-
0035968185
-
Hormone-induced conformational change of the purified soluble hormone binding domain of follitropin receptor complexed with single chain follitropin
-
Schmidt A., et al. Hormone-induced conformational change of the purified soluble hormone binding domain of follitropin receptor complexed with single chain follitropin. J. Biol. Chem. 276:2001;23373-23381.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 23373-23381
-
-
Schmidt, A.1
-
7
-
-
0035910404
-
Purification and structural analysis of a soluble human chorionogonadotropin hormone-receptor complex
-
Remy J.J., et al. Purification and structural analysis of a soluble human chorionogonadotropin hormone-receptor complex. J. Biol. Chem. 276:2001;1681-1687.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 1681-1687
-
-
Remy, J.J.1
-
8
-
-
0035928771
-
Purification and characterization of a soluble bioactive amino-terminal extracellular domain of the human thyrotropin receptor
-
Cornelis S., et al. Purification and characterization of a soluble bioactive amino-terminal extracellular domain of the human thyrotropin receptor. Biochemistry. 40:2001;9860-9869.
-
(2001)
Biochemistry
, vol.40
, pp. 9860-9869
-
-
Cornelis, S.1
-
9
-
-
0028239813
-
Crystal structure of human chorionic gonadotropin
-
Lapthorn A.J., et al. Crystal structure of human chorionic gonadotropin. Nature. 369:1994;455-461.
-
(1994)
Nature
, vol.369
, pp. 455-461
-
-
Lapthorn, A.J.1
-
10
-
-
0028773646
-
Structure of human chorionic gonadotropin at 2.6 Å resolution from MAD analysis of the selenomethionyl protein
-
Wu H., et al. Structure of human chorionic gonadotropin at 2.6 Å resolution from MAD analysis of the selenomethionyl protein. Structure. 2:1994;545-558.
-
(1994)
Structure
, vol.2
, pp. 545-558
-
-
Wu, H.1
-
11
-
-
0035105355
-
Three-dimensional structure of human follicle-stimulating hormone
-
Fox K.M., et al. Three-dimensional structure of human follicle-stimulating hormone. Mol. Endocrinol. 15:2001;378-389.
-
(2001)
Mol. Endocrinol.
, vol.15
, pp. 378-389
-
-
Fox, K.M.1
-
12
-
-
0029645408
-
Modeling of the three-dimensional structure of proteins with the typical leucine-rich repeats
-
Kajava A.V., et al. Modeling of the three-dimensional structure of proteins with the typical leucine-rich repeats. Structure. 3:1995;867-877.
-
(1995)
Structure
, vol.3
, pp. 867-877
-
-
Kajava, A.V.1
-
13
-
-
0029646089
-
Structural predictions for the ligand-binding region of glycoprotein hormone receptors and the nature of hormone-receptor interactions
-
Jiang X., et al. Structural predictions for the ligand-binding region of glycoprotein hormone receptors and the nature of hormone-receptor interactions. Structure. 3:1995;1341-1353.
-
(1995)
Structure
, vol.3
, pp. 1341-1353
-
-
Jiang, X.1
-
14
-
-
0029757509
-
Determination of residues important in hormone binding to the extracellular domain of the luteinizing hormone/chorionic gonadotropin receptor by site-directed mutagenesis and modeling
-
Bhowmick N., et al. Determination of residues important in hormone binding to the extracellular domain of the luteinizing hormone/chorionic gonadotropin receptor by site-directed mutagenesis and modeling. Mol. Endocrinol. 10:1996;1147-1159.
-
(1996)
Mol. Endocrinol.
, vol.10
, pp. 1147-1159
-
-
Bhowmick, N.1
-
15
-
-
0027718173
-
Crystal structure of porcine ribonuclease inhibitor, a protein with leucine-rich repeats
-
Kobe B., Deisenhofer J. Crystal structure of porcine ribonuclease inhibitor, a protein with leucine-rich repeats. Nature. 366:1993;751-756.
-
(1993)
Nature
, vol.366
, pp. 751-756
-
-
Kobe, B.1
Deisenhofer, J.2
-
16
-
-
0038182549
-
Glycoprotein hormone receptors: Determinants in leucine-rich repeats responsible for ligand specificity
-
Smits G., et al. Glycoprotein hormone receptors: determinants in leucine-rich repeats responsible for ligand specificity. EMBO J. 22:2003;2692-2703.
-
(2003)
EMBO J.
, vol.22
, pp. 2692-2703
-
-
Smits, G.1
-
17
-
-
0030852648
-
Novel insights into the molecular mechanisms of human thyrotropin action: Structural, physiological, and therapeutic implications for the glycoprotein hormone family
-
Grossmann M., et al. Novel insights into the molecular mechanisms of human thyrotropin action: structural, physiological, and therapeutic implications for the glycoprotein hormone family. Endocr. Rev. 18:1997;476-501.
-
(1997)
Endocr. Rev.
, vol.18
, pp. 476-501
-
-
Grossmann, M.1
-
18
-
-
0028330517
-
Co-evolution of ligand-receptor pairs
-
Moyle W.R., et al. Co-evolution of ligand-receptor pairs. Nature. 368:1994;251-255.
-
(1994)
Nature
, vol.368
, pp. 251-255
-
-
Moyle, W.R.1
-
19
-
-
0027999473
-
Receptor binding and functional properties of chimeric human follitropin prepared by an exchange between a small hydrophilic intercysteine loop of human follitropin and human lutropin
-
Dias J.A., et al. Receptor binding and functional properties of chimeric human follitropin prepared by an exchange between a small hydrophilic intercysteine loop of human follitropin and human lutropin. J. Biol. Chem. 269:1994;25289-25294.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 25289-25294
-
-
Dias, J.A.1
-
20
-
-
0032542355
-
Familial gestational hyperthyroidism caused by a mutant thyrotropin receptor hypersensitive to human chorionic gonadotropin
-
Rodien P., et al. Familial gestational hyperthyroidism caused by a mutant thyrotropin receptor hypersensitive to human chorionic gonadotropin. N. Engl. J. Med. 339:1998;1823-1826.
-
(1998)
N. Engl. J. Med.
, vol.339
, pp. 1823-1826
-
-
Rodien, P.1
-
21
-
-
0036218255
-
Lysine 183 and glutamic acid 157 of the thyrotropin receptor: Two interacting residues with a key role in determining specificity towards TSH and hCG
-
Smits G., et al. Lysine 183 and glutamic acid 157 of the thyrotropin receptor: two interacting residues with a key role in determining specificity towards TSH and hCG. Mol. Endocrinol. 1:2002;722-735.
-
(2002)
Mol. Endocrinol.
, vol.1
, pp. 722-735
-
-
Smits, G.1
-
22
-
-
0041464853
-
Ovarian hyperstimulation syndrome due to a mutation in the follicle-stimulating hormone receptor
-
Smits G., et al. Ovarian hyperstimulation syndrome due to a mutation in the follicle-stimulating hormone receptor. N. Engl. J. Med. 349:2003;760-766.
-
(2003)
N. Engl. J. Med.
, vol.349
, pp. 760-766
-
-
Smits, G.1
-
23
-
-
0041966031
-
A chorionic gonadotropin-sensitive mutation in the follicle-stimulating hormone receptor as a cause of familial gestational spontaneous ovarian hyperstimulation syndrome
-
Vasseur C., et al. A chorionic gonadotropin-sensitive mutation in the follicle-stimulating hormone receptor as a cause of familial gestational spontaneous ovarian hyperstimulation syndrome. N. Engl. J. Med. 349:2003;753-759.
-
(2003)
N. Engl. J. Med.
, vol.349
, pp. 753-759
-
-
Vasseur, C.1
-
24
-
-
0037084011
-
Tyrosine sulfation is required for agonist recognition by glycoprotein hormone receptors
-
Costagliola S., et al. Tyrosine sulfation is required for agonist recognition by glycoprotein hormone receptors. EMBO J. 21:2002;504-513.
-
(2002)
EMBO J.
, vol.21
, pp. 504-513
-
-
Costagliola, S.1
-
25
-
-
0035907254
-
Tyrosine sulfation of glycoprotein I(b)α. Role of electrostatic interactions in von Willebrand factor binding
-
Dong J., et al. Tyrosine sulfation of glycoprotein I(b)α. Role of electrostatic interactions in von Willebrand factor binding. J. Biol. Chem. 276:2001;16690-16694.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 16690-16694
-
-
Dong, J.1
-
26
-
-
0034604451
-
Crystal structure of rhodopsin: A G protein-coupled receptor
-
Palczewski K., et al. Crystal structure of rhodopsin: A G protein-coupled receptor. Science. 289:2000;739-745.
-
(2000)
Science
, vol.289
, pp. 739-745
-
-
Palczewski, K.1
-
27
-
-
0642306488
-
Phototransduction: Crystal clear
-
Ridge K.D., et al. Phototransduction: crystal clear. Trends Biochem. Sci. 28:2003;479-487.
-
(2003)
Trends Biochem. Sci.
, vol.28
, pp. 479-487
-
-
Ridge, K.D.1
-
28
-
-
8544221172
-
Diversity and prevalence of somatic mutations in the TSH receptor and Gsα genes as a cause of toxic thyroid adenomas
-
Parma J., et al. Diversity and prevalence of somatic mutations in the TSH receptor and Gsα genes as a cause of toxic thyroid adenomas. J. Clin. Endocrinol. Metab. 82:1997;2695-2701.
-
(1997)
J. Clin. Endocrinol. Metab.
, vol.82
, pp. 2695-2701
-
-
Parma, J.1
-
30
-
-
0035989009
-
Activating mutations of the lutropin choriogonadotropin receptor in precocious puberty
-
Shenker A. Activating mutations of the lutropin choriogonadotropin receptor in precocious puberty. Receptors Channels. 8:2002;3-18.
-
(2002)
Receptors Channels
, vol.8
, pp. 3-18
-
-
Shenker, A.1
-
31
-
-
0028240982
-
Germline mutations in the thyrotropin receptor gene cause non autoimmune autosomal dominant hyperthyroidism
-
Duprez L., et al. Germline mutations in the thyrotropin receptor gene cause non autoimmune autosomal dominant hyperthyroidism. Nat. Genet. 7:1994;396-401.
-
(1994)
Nat. Genet.
, vol.7
, pp. 396-401
-
-
Duprez, L.1
-
32
-
-
0035933839
-
A conserved ASN in TM7 is a on/off switch in the activation of the TSH receptor
-
Govaerts C., et al. A conserved ASN in TM7 is a on/off switch in the activation of the TSH receptor. J. Biol. Chem. 276:2001;22991-22999.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 22991-22999
-
-
Govaerts, C.1
-
33
-
-
0030912536
-
A model of the lutropin/choriogonadotropin receptor: Insights into the structural and functional effects of constitutively activating mutations
-
Lin Z., et al. A model of the lutropin/choriogonadotropin receptor: insights into the structural and functional effects of constitutively activating mutations. Protein Eng. 10:1997;501-510.
-
(1997)
Protein Eng.
, vol.10
, pp. 501-510
-
-
Lin, Z.1
-
34
-
-
0034895145
-
A free carboxylate oxygen in the side chain of position 674 in transmembrane domain 7 is necessary for TSH receptor activation
-
Neumann S., et al. A free carboxylate oxygen in the side chain of position 674 in transmembrane domain 7 is necessary for TSH receptor activation. Mol. Endocrinol. 15:2001;1294-1305.
-
(2001)
Mol. Endocrinol.
, vol.15
, pp. 1294-1305
-
-
Neumann, S.1
-
35
-
-
0037197848
-
Functional role of internal water molecules in rhodopsin revealed by X-ray crystallography
-
Okada T., et al. Functional role of internal water molecules in rhodopsin revealed by X-ray crystallography. Proc. Natl. Acad. Sci. U. S. A. 99:2002;5982-5987.
-
(2002)
Proc. Natl. Acad. Sci. U. S. A.
, vol.99
, pp. 5982-5987
-
-
Okada, T.1
-
36
-
-
0028031727
-
A reciprocal mutation supports helix 2 and helix 7 proximity in the gonadotropin-releasing hormone receptor
-
Zhou W., et al. A reciprocal mutation supports helix 2 and helix 7 proximity in the gonadotropin-releasing hormone receptor. Mol. Pharmacol. 45:1994;165-170.
-
(1994)
Mol. Pharmacol.
, vol.45
, pp. 165-170
-
-
Zhou, W.1
-
37
-
-
0029011757
-
Related contribution of specific helix 2 and 7 residues to conformational activation of the serotonin 5-HT2A receptor
-
Sealfon S.C., et al. Related contribution of specific helix 2 and 7 residues to conformational activation of the serotonin 5-HT2A receptor. J. Biol. Chem. 270:1995;16683-16688.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 16683-16688
-
-
Sealfon, S.C.1
-
38
-
-
0344406765
-
Role of the conserved NPxxY(x)5,6F motif in the rhodopsin ground state and during activation
-
Fritze O., et al. Role of the conserved NPxxY(x)5,6F motif in the rhodopsin ground state and during activation. Proc. Natl. Acad. Sci. U. S. A. 100:2003;2290-2295.
-
(2003)
Proc. Natl. Acad. Sci. U. S. A.
, vol.100
, pp. 2290-2295
-
-
Fritze, O.1
-
39
-
-
0037165664
-
A conserved Asn in TM7 of the TSH receptor is a common requirement for activation by both mutations and its natural agonist
-
Claeysen S., et al. A conserved Asn in TM7 of the TSH receptor is a common requirement for activation by both mutations and its natural agonist. FEBS Lett. 517:2002;195-200.
-
(2002)
FEBS Lett.
, vol.517
, pp. 195-200
-
-
Claeysen, S.1
-
40
-
-
0035800850
-
Activation of the β2-adrenergic receptor involves disruption of an ionic lock between the cytoplasmic ends of transmembrane segments 3 and 6
-
Ballesteros J.A., et al. Activation of the β2-adrenergic receptor involves disruption of an ionic lock between the cytoplasmic ends of transmembrane segments 3 and 6. J. Biol. Chem. 276:2001;29171-29177.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 29171-29177
-
-
Ballesteros, J.A.1
-
41
-
-
0030805829
-
Constitutive activation of the TSH receptor by spontaneous mutations affecting the N-terminal extracellular domain
-
Duprez L., et al. Constitutive activation of the TSH receptor by spontaneous mutations affecting the N-terminal extracellular domain. FEBS Lett. 409:1997;469-474.
-
(1997)
FEBS Lett.
, vol.409
, pp. 469-474
-
-
Duprez, L.1
-
42
-
-
0030830146
-
Congenital hyperthyroidism caused by a solitary toxic adenoma harboring a novel somatic mutation (serine281(isoleucine) in the extracellular domain of the thyrotropin receptor
-
Kopp P., et al. Congenital hyperthyroidism caused by a solitary toxic adenoma harboring a novel somatic mutation (serine281(isoleucine) in the extracellular domain of the thyrotropin receptor. J. Clin. Invest. 100:1997;1634-1639.
-
(1997)
J. Clin. Invest.
, vol.100
, pp. 1634-1639
-
-
Kopp, P.1
-
43
-
-
0034730516
-
Activation of the luteinizing hormone receptor following substitution of Ser-277 with selective hydrophobic residues in the ectodomain hinge region
-
Nakabayashi K., et al. Activation of the luteinizing hormone receptor following substitution of Ser-277 with selective hydrophobic residues in the ectodomain hinge region. J. Biol. Chem. 275:2000;30264-30271.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 30264-30271
-
-
Nakabayashi, K.1
-
44
-
-
0034987731
-
Effects of mutations involving the highly conserved S281HCC motif in the extracellular domain of the thyrotropin (TSH) receptor on TSH binding and constitutive activity
-
Ho S.C., et al. Effects of mutations involving the highly conserved S281HCC motif in the extracellular domain of the thyrotropin (TSH) receptor on TSH binding and constitutive activity. Endocrinology. 142:2001;2760-2767.
-
(2001)
Endocrinology
, vol.142
, pp. 2760-2767
-
-
Ho, S.C.1
-
46
-
-
0029888302
-
Specific activation of the thyrotropin receptor by trypsin
-
Van Sande J., et al. Specific activation of the thyrotropin receptor by trypsin. Mol. Cell. Endocrinol. 119:1996;161-168.
-
(1996)
Mol. Cell. Endocrinol.
, vol.119
, pp. 161-168
-
-
Van Sande, J.1
-
47
-
-
0034457935
-
The extracellular domain suppresses constitutive activity of the transmembrane domain of the human TSH receptor: Implications for hormone-receptor interaction and antagonist design
-
Zhang M., et al. The extracellular domain suppresses constitutive activity of the transmembrane domain of the human TSH receptor: implications for hormone-receptor interaction and antagonist design. Endocrinology. 141:2000;3514-3517.
-
(2000)
Endocrinology
, vol.141
, pp. 3514-3517
-
-
Zhang, M.1
-
48
-
-
0036214718
-
Activation of the cAMP pathway by the TSH receptor involves switching of the ectodomain from a tethered inverse agonist to an agonist
-
Vlaeminck V., et al. Activation of the cAMP pathway by the TSH receptor involves switching of the ectodomain from a tethered inverse agonist to an agonist. Mol. Endocrinol. 16:2002;736-746.
-
(2002)
Mol. Endocrinol.
, vol.16
, pp. 736-746
-
-
Vlaeminck, V.1
-
49
-
-
0037040202
-
The ectodomain of the luteinizing hormone receptor interacts with exoloop 2 to constrain the transmembrane region: Studies using chimeric human and fly receptors
-
Nishi S., et al. The ectodomain of the luteinizing hormone receptor interacts with exoloop 2 to constrain the transmembrane region: studies using chimeric human and fly receptors. J. Biol. Chem. 277:2002;3958-3964.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 3958-3964
-
-
Nishi, S.1
-
50
-
-
0025776460
-
Composite structure of the human thyrotropin receptor gene
-
Gross B., et al. Composite structure of the human thyrotropin receptor gene. Biochem. Biophys. Res. Commun. 177:1991;679-687.
-
(1991)
Biochem. Biophys. Res. Commun.
, vol.177
, pp. 679-687
-
-
Gross, B.1
-
51
-
-
0027751626
-
Molecular cloning of a novel, putative G protein-coupled receptor from sea anemones structurally related to members of the FSH, TSH, LH/CG receptor family from mammals
-
Nothacker H.P., Grimmelikhuijzen C.J. Molecular cloning of a novel, putative G protein-coupled receptor from sea anemones structurally related to members of the FSH, TSH, LH/CG receptor family from mammals. Biochem. Biophys. Res. Commun. 197:1993;1062-1069.
-
(1993)
Biochem. Biophys. Res. Commun.
, vol.197
, pp. 1062-1069
-
-
Nothacker, H.P.1
Grimmelikhuijzen, C.J.2
-
52
-
-
0036865059
-
Epidemiology and prevention of ovarian hyperstimulation syndrome (OHSS): A review
-
Delvigne A., Rozenberg S. Epidemiology and prevention of ovarian hyperstimulation syndrome (OHSS): a review. Hum. Reprod. Update. 8:2002;559-577.
-
(2002)
Hum. Reprod. Update
, vol.8
, pp. 559-577
-
-
Delvigne, A.1
Rozenberg, S.2
-
53
-
-
0029832901
-
Transmembrane regions V and VI of the human luteinizing hormone receptor are required for constitutive activation by a mutation in the third intracellular loop
-
Kudo M., et al. Transmembrane regions V and VI of the human luteinizing hormone receptor are required for constitutive activation by a mutation in the third intracellular loop. J. Biol. Chem. 271:1996;22470-22478.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 22470-22478
-
-
Kudo, M.1
-
54
-
-
0036895765
-
A monoclonal thyroid-stimulating antibody
-
Ando T., et al. A monoclonal thyroid-stimulating antibody. J. Clin. Invest. 110:2002;1667-1674.
-
(2002)
J. Clin. Invest.
, vol.110
, pp. 1667-1674
-
-
Ando, T.1
-
55
-
-
12244265471
-
Thyroid stimulating monoclonal antibodies
-
Sanders J., et al. Thyroid stimulating monoclonal antibodies. Thyroid. 12:2002;1043-1050.
-
(2002)
Thyroid
, vol.12
, pp. 1043-1050
-
-
Sanders, J.1
-
56
-
-
0036921438
-
Generation of a mouse monoclonal TSH receptor antibody with stimulating activity
-
Costagliola S., et al. Generation of a mouse monoclonal TSH receptor antibody with stimulating activity. Biochem. Biophys. Res. Commun. 299:2002;891-896.
-
(2002)
Biochem. Biophys. Res. Commun.
, vol.299
, pp. 891-896
-
-
Costagliola, S.1
-
57
-
-
85047686522
-
Cis- and trans-activation of hormone receptors: The LH receptor
-
Ji I., et al. Cis- and trans-activation of hormone receptors: the LH receptor. Mol. Endocrinol. 16:2002;1299-1308.
-
(2002)
Mol. Endocrinol.
, vol.16
, pp. 1299-1308
-
-
Ji, I.1
-
58
-
-
0037013328
-
Two defective heterozygous luteinizing hormone receptors can rescue hormone action
-
Lee C., et al. Two defective heterozygous luteinizing hormone receptors can rescue hormone action. J. Biol. Chem. 277:2002;15795-15800.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 15795-15800
-
-
Lee, C.1
-
59
-
-
0035692811
-
The leucine-rich repeat as a protein recognition motif
-
Kobe B., Kajava A.V. The leucine-rich repeat as a protein recognition motif. Curr. Opin. Struct. Biol. 11:2001;725-732.
-
(2001)
Curr. Opin. Struct. Biol.
, vol.11
, pp. 725-732
-
-
Kobe, B.1
Kajava, A.V.2
-
60
-
-
0027369421
-
Somatic mutations in the thyrotropin receptor gene cause hyperfunctioning thyroid adenomas
-
Parma J., et al. Somatic mutations in the thyrotropin receptor gene cause hyperfunctioning thyroid adenomas. Nature. 365:1993;649-651.
-
(1993)
Nature
, vol.365
, pp. 649-651
-
-
Parma, J.1
|