메뉴 건너뛰기




Volumn 265, Issue 3, 1999, Pages 1022-1031

Autoantibodies interacting with purified native thyrotropin receptor

Author keywords

Autoantibodies; ELISA; Graves' disease; Native receptor; Thyrotropin receptor

Indexed keywords

ADENYLATE CYCLASE; AUTOANTIBODY; CYCLIC AMP; EPITOPE; IMMUNOGLOBULIN G; RECEPTOR ANTIBODY; THYROTROPIN RECEPTOR;

EID: 0033231269     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1432-1327.1999.00816.x     Document Type: Article
Times cited : (33)

References (52)
  • 1
    • 0028579773 scopus 로고
    • Autoimmune thyroid disease: Further developments in our understanding
    • 1. Weetman, A.P. & McGregor, A.M. (1994) Autoimmune thyroid disease: further developments in our understanding. Endocrinol. Rev. 15, 788-830.
    • (1994) Endocrinol. Rev. , vol.15 , pp. 788-830
    • Weetman, A.P.1    McGregor, A.M.2
  • 3
    • 0022039971 scopus 로고
    • Immune mechanisms in Graves' disease
    • 3. Burman, K.D. & Baker, J.R. (1985) Immune mechanisms in Graves' disease. Endocrinol. Rev. 6, 183-232.
    • (1985) Endocrinol. Rev. , vol.6 , pp. 183-232
    • Burman, K.D.1    Baker, J.R.2
  • 4
    • 0023544854 scopus 로고
    • The spectrum and significance of autoantibodies reacting with the thyrotropin receptor
    • 4. Zakarija, M. & McKenzie, M. (1987) The spectrum and significance of autoantibodies reacting with the thyrotropin receptor. Endocrinol. Metab. Clin. North Am. 16, 343-363.
    • (1987) Endocrinol. Metab. Clin. North Am. , vol.16 , pp. 343-363
    • Zakarija, M.1    McKenzie, M.2
  • 5
    • 0022621749 scopus 로고
    • Detection of autoantibodies to thyroid peroxidase in autoimmune thyroid diseases by micro-ELISA and immunoblotting
    • 5. Kotani, T., Umeki, K., Matsunaga, S., Kato, E. & Ohtaki, S. (1986) Detection of autoantibodies to thyroid peroxidase in autoimmune thyroid diseases by micro-ELISA and immunoblotting. J. Clin. Endocrinol. Metab. 62, 928-933.
    • (1986) J. Clin. Endocrinol. Metab. , vol.62 , pp. 928-933
    • Kotani, T.1    Umeki, K.2    Matsunaga, S.3    Kato, E.4    Ohtaki, S.5
  • 6
    • 0023914740 scopus 로고
    • Autoantibodies to the thyroid microsomal/thyroid peroxidase antigen are polyclonal and directed to several distinct antigenic sites
    • 6. Doble, N.D., Banga, J.P., Pope, R., Lalor, E., Kilduff, P. & McGregor, A.M. (1988) Autoantibodies to the thyroid microsomal/thyroid peroxidase antigen are polyclonal and directed to several distinct antigenic sites. Immunology. 64, 23-29.
    • (1988) Immunology , vol.64 , pp. 23-29
    • Doble, N.D.1    Banga, J.P.2    Pope, R.3    Lalor, E.4    Kilduff, P.5    McGregor, A.M.6
  • 8
    • 0027415791 scopus 로고
    • Quantitative measurement of human thyroglobulinspecific antibodies by use of a sensitive enzyme-linked immunoassay
    • 8. Kuppers, R.C., Outschoorn, I.M., Hamilton, R.G., Burek, C.L. & Rose, N.R. (1993) Quantitative measurement of human thyroglobulinspecific antibodies by use of a sensitive enzyme-linked immunoassay. Clin. Immunol. Immunopathol 67, 68-77.
    • (1993) Clin. Immunol. Immunopathol. , vol.67 , pp. 68-77
    • Kuppers, R.C.1    Outschoorn, I.M.2    Hamilton, R.G.3    Burek, C.L.4    Rose, N.R.5
  • 9
    • 0028944837 scopus 로고
    • Continuous versus discontinuous B-cell epitopes on thyroid-specific autoantigens-thyrotropin receptor and thyroid peroxidase
    • 9. Nagayama, Y. (1995) Continuous versus discontinuous B-cell epitopes on thyroid-specific autoantigens-thyrotropin receptor and thyroid peroxidase. Eur. J. Endocrinol. 132, 9-11.
    • (1995) Eur. J. Endocrinol. , vol.132 , pp. 9-11
    • Nagayama, Y.1
  • 11
    • 0030872099 scopus 로고    scopus 로고
    • Immunoglobulin Gk antithyroid peroxidase antibodies in Hashimoto's thyroiditis: Epitope-mapping analysis
    • 11. Czarnocka, B., Janota-Bzowski, M. & Mcintosh, R.S. (1997) Immunoglobulin Gk antithyroid peroxidase antibodies in Hashimoto's thyroiditis: epitope-mapping analysis. J. Clin. Endocrinol. Metab. 82, 2639-2644.
    • (1997) J. Clin. Endocrinol. Metab. , vol.82 , pp. 2639-2644
    • Czarnocka, B.1    Janota-Bzowski, M.2    Mcintosh, R.S.3
  • 12
    • 0029983114 scopus 로고    scopus 로고
    • Unique autoantibody epitopes in an immunodominant region of thyroid peroxidase
    • 12. Arscott, P.L., Koening, R.J., Kaplan, M.M., Glick, G.D. & Baker, J.R. (1996) Unique autoantibody epitopes in an immunodominant region of thyroid peroxidase. J. Biol. Chem. 271, 4966-4973.
    • (1996) J. Biol. Chem. , vol.271 , pp. 4966-4973
    • Arscott, P.L.1    Koening, R.J.2    Kaplan, M.M.3    Glick, G.D.4    Baker, J.R.5
  • 14
    • 0026342948 scopus 로고
    • Autoimmunity to human thyroglobulin. Respective epitopic specificity patterns of anti-human thyroglobulin autoantibodies in patients with Sjögren's syndrome and patients with Hashimoto's thyroiditis
    • 14. Bouanani, M., Bataille, R., Piechaczyk, M., Salhi, S.L., Pau, B. & Bastide, M. (1991) Autoimmunity to human thyroglobulin. Respective epitopic specificity patterns of anti-human thyroglobulin autoantibodies in patients with Sjögren's syndrome and patients with Hashimoto's thyroiditis. Arthritis Rheum. 34, 1585-1593.
    • (1991) Arthritis Rheum. , vol.34 , pp. 1585-1593
    • Bouanani, M.1    Bataille, R.2    Piechaczyk, M.3    Salhi, S.L.4    Pau, B.5    Bastide, M.6
  • 16
    • 0024310223 scopus 로고
    • Clinical review 3. The clinical use of thyrotropin receptor antibody measurements
    • 16. McKenzie, J.M. & Zakarija, M. (1989) Clinical review 3. The clinical use of thyrotropin receptor antibody measurements. J. Clin. Endocrinol. Metab. 69, 1093-1096.
    • (1989) J. Clin. Endocrinol. Metab. , vol.69 , pp. 1093-1096
    • McKenzie, J.M.1    Zakarija, M.2
  • 17
    • 0024991730 scopus 로고
    • Use of the recombinant human thyrotropin receptor (TSH-R) expressed in mammalian cell lines to assay TSH-R autoantibodies
    • 17. Ludgate, M., Perret, J., Parmentier, M., Gerard, C., Libert, F., Dumont, J.E. & Vassart, G. (1990), Use of the recombinant human thyrotropin receptor (TSH-R) expressed in mammalian cell lines to assay TSH-R autoantibodies. Mol. Cell. Endocrinol. 73, R13-R18.
    • (1990) Mol. Cell. Endocrinol. , vol.73
    • Ludgate, M.1    Perret, J.2    Parmentier, M.3    Gerard, C.4    Libert, F.5    Dumont, J.E.6    Vassart, G.7
  • 18
    • 0026509995 scopus 로고
    • Expression of a human thyrotropin receptor fragment in Escherichia coli and its interaction with the hormone and autoantibodies from patients with Graves' disease
    • 18. Huang, G.C., Collison, K.S., McGregor, A.M. & Banga, J.P. (1992) Expression of a human thyrotropin receptor fragment in Escherichia coli and its interaction with the hormone and autoantibodies from patients with Graves' disease. J. Mol. Endocrinol. 8, 137-144.
    • (1992) J. Mol. Endocrinol. , vol.8 , pp. 137-144
    • Huang, G.C.1    Collison, K.S.2    McGregor, A.M.3    Banga, J.P.4
  • 19
    • 0026580027 scopus 로고
    • The use of the amplifiable high-expression vector pEE14 to study the interactions of autoantibodies with recombinant human thyrotrophin receptor
    • 19. Harfst, E., Johnstone, A.P., Gout, I., Taylor, A.H., Waterfield, M.D. & Nussey, S.S. (1992) The use of the amplifiable high-expression vector pEE14 to study the interactions of autoantibodies with recombinant human thyrotrophin receptor. Mol. Cell Endocrinol. 83, 117-123.
    • (1992) Mol. Cell Endocrinol. , vol.83 , pp. 117-123
    • Harfst, E.1    Johnstone, A.P.2    Gout, I.3    Taylor, A.H.4    Waterfield, M.D.5    Nussey, S.S.6
  • 20
    • 0026491141 scopus 로고
    • Characterization of the extracellular region of the human thyrotrophin receptor expressed as a recombinant protein
    • 20. Harfst, E., Johnstone, A.P. & Nussey, S.S. (1992) Characterization of the extracellular region of the human thyrotrophin receptor expressed as a recombinant protein. J. Mol. Endocrinol. 9, 227-236.
    • (1992) J. Mol. Endocrinol. , vol.9 , pp. 227-236
    • Harfst, E.1    Johnstone, A.P.2    Nussey, S.S.3
  • 21
    • 0027752375 scopus 로고
    • Analysis of autoantibody reactivity in patients with Graves' disease using recombinant extracellular domain of the human thyrotropin receptor and synthetic peptides
    • 21. Fan, J.L., Seetharamaiah, G.S., Desai, R.K., Dallas, J.S., Wagle, N.M. & Prabhakar, B.S. (1993) Analysis of autoantibody reactivity in patients with Graves' disease using recombinant extracellular domain of the human thyrotropin receptor and synthetic peptides. Autoimmunity 15, 285-291.
    • (1993) Autoimmunity , vol.15 , pp. 285-291
    • Fan, J.L.1    Seetharamaiah, G.S.2    Desai, R.K.3    Dallas, J.S.4    Wagle, N.M.5    Prabhakar, B.S.6
  • 22
    • 0027416670 scopus 로고
    • The thyrotrophin hormone receptor of Graves' disease: Overexpression of the extracellular domain in insect cells using recombinant baculovirus, immunoaffinity purification and analysis of autoantibody binding
    • 22. Huang, G.C., Page, M.J., Nicholson, L.B., Collison, K.S., McGregor, A.M. & Banga, J.P. (1993) The thyrotrophin hormone receptor of Graves' disease: overexpression of the extracellular domain in insect cells using recombinant baculovirus, immunoaffinity purification and analysis of autoantibody binding. J. Mol. Endocrinol. 10, 127-142.
    • (1993) J. Mol. Endocrinol. , vol.10 , pp. 127-142
    • Huang, G.C.1    Page, M.J.2    Nicholson, L.B.3    Collison, K.S.4    McGregor, A.M.5    Banga, J.P.6
  • 23
    • 0030020709 scopus 로고    scopus 로고
    • Binding of antithyrotropin receptor autoantibodies in Graves' disease serum to nascent, in vitro translated thyrotropin receptor: Ability to map epitopes recognized by antibodies
    • 23. Morgenthaler, N.G., Tremble, J., Huang, G., Scherbaum, W.A., McGregor, A.M. & Banga, J.P. (1996) Binding of antithyrotropin receptor autoantibodies in Graves' disease serum to nascent, in vitro translated thyrotropin receptor: ability to map epitopes recognized by antibodies. J. Clin. Endocrinol. Metab. 81, 700-706.
    • (1996) J. Clin. Endocrinol. Metab. , vol.81 , pp. 700-706
    • Morgenthaler, N.G.1    Tremble, J.2    Huang, G.3    Scherbaum, W.A.4    McGregor, A.M.5    Banga, J.P.6
  • 24
    • 0030954970 scopus 로고    scopus 로고
    • Thyrotropin (TSH) receptor autoantibodies do not appear to bind to the TSH receptor produced in an in vitro transcription/translation system
    • 24. Prentice, L., Sanders, J.F., Perez, M., Kato, R., Sawicka, J., Oda, Y., Jaskolski, D., Furmaniak, J. & Rees Smith, B. (1997) Thyrotropin (TSH) receptor autoantibodies do not appear to bind to the TSH receptor produced in an in vitro transcription/translation system. J. Clin. Endocrinol. Metab. 82, 1288-1292.
    • (1997) J. Clin. Endocrinol. Metab. , vol.82 , pp. 1288-1292
    • Prentice, L.1    Sanders, J.F.2    Perez, M.3    Kato, R.4    Sawicka, J.5    Oda, Y.6    Jaskolski, D.7    Furmaniak, J.8    Rees Smith, B.9
  • 25
    • 0030989993 scopus 로고    scopus 로고
    • The antibody response in human autoimmune thyroid disease
    • 25. McIntosh, R.S., Asghar, M.S. & Weetman, A.P. (1997) The antibody response in human autoimmune thyroid disease. Clin. Sci. 92, 529-541.
    • (1997) Clin. Sci. , vol.92 , pp. 529-541
    • McIntosh, R.S.1    Asghar, M.S.2    Weetman, A.P.3
  • 26
    • 0025949715 scopus 로고
    • Thyroperoxidase, but not the thyrotropin receptor, contains sequential epitopes recognized by autoantibodies in recombinant peptides expressed in the pUEX vector
    • 26. Libert, F., Ludgate, M., Dinsart, C. & Vassart, G. (1991) Thyroperoxidase, but not the thyrotropin receptor, contains sequential epitopes recognized by autoantibodies in recombinant peptides expressed in the pUEX vector. J. Clin. Endocrinol. Metab. 73, 857-860.
    • (1991) J. Clin. Endocrinol. Metab. , vol.73 , pp. 857-860
    • Libert, F.1    Ludgate, M.2    Dinsart, C.3    Vassart, G.4
  • 27
    • 0030909929 scopus 로고    scopus 로고
    • Folding-dependent binding of thyrotropin (TSH) and TSH receptor autoantibodies to the murine TSH receptor ectodomain
    • 27. Vlase, H., Matsuoka, N., Graves, P.N., Magnusson, R.P. & Davies, T.F. (1997) Folding-dependent binding of thyrotropin (TSH) and TSH receptor autoantibodies to the murine TSH receptor ectodomain. Endocrinology. 138, 1658-1666.
    • (1997) Endocrinology , vol.138 , pp. 1658-1666
    • Vlase, H.1    Matsuoka, N.2    Graves, P.N.3    Magnusson, R.P.4    Davies, T.F.5
  • 28
    • 0030752377 scopus 로고    scopus 로고
    • Engineering the human thyrotropin receptor ectodomain from a non-secreted form to a secreted, highly immunoreactive glycoprotein that neutralizes autoantibodies in Graves' patients' sera
    • 28. Chazenbalk, G.D., Jaume, J.C., McLachlan, S.M. & Rapoport, B. (1997) Engineering the human thyrotropin receptor ectodomain from a non-secreted form to a secreted, highly immunoreactive glycoprotein that neutralizes autoantibodies in Graves' patients' sera. J. Biol. Chem. 272, 18959-18965.
    • (1997) J. Biol. Chem. , vol.272 , pp. 18959-18965
    • Chazenbalk, G.D.1    Jaume, J.C.2    McLachlan, S.M.3    Rapoport, B.4
  • 29
    • 0028225588 scopus 로고
    • Processing of the precursors of the human thyroid-stimulating hormone receptor in various eukaryotic cells (human thyrocytes, transfected L cells and baculovirus-infected insect cells)
    • 29. Misrahi, M., Ghinéa, N., Sar, S., Saunier, B., Jolivet, A., Loosfelt, H., Cerutti, M., Devauchelle, G. & Milgrom, E. (1994) Processing of the precursors of the human thyroid-stimulating hormone receptor in various eukaryotic cells (human thyrocytes, transfected L cells and baculovirus-infected insect cells). Eur J. Biochem. 222, 711-719.
    • (1994) Eur J. Biochem. , vol.222 , pp. 711-719
    • Misrahi, M.1    Ghinéa, N.2    Sar, S.3    Saunier, B.4    Jolivet, A.5    Loosfelt, H.6    Cerutti, M.7    Devauchelle, G.8    Milgrom, E.9
  • 31
    • 0021055378 scopus 로고
    • Monoclonal antibodies to rabbit progesterone receptor. Cross-reaction with other mammalian progesterone receptors
    • 31. Logeat, F., Vu Hai, M.T., Fournier, A., Legrain, P., Buttin, G. & Milgrom, E. (1983). Monoclonal antibodies to rabbit progesterone receptor. Cross-reaction with other mammalian progesterone receptors. Proc. Natl Acad. Sci. USA. 80, 6456-6459.
    • (1983) Proc. Natl Acad. Sci. USA , vol.80 , pp. 6456-6459
    • Logeat, F.1    Vu Hai, M.T.2    Fournier, A.3    Legrain, P.4    Buttin, G.5    Milgrom, E.6
  • 32
    • 0009484215 scopus 로고    scopus 로고
    • Shedding of human thyrotropin receptor ectodomain. Involvement of a matrix metalloprotease
    • 32. Couët, J., Sar, S., Jolivet, A., Vu Hai, M.T., Milgrom, E. & Misrahi, M. (1996) Shedding of human thyrotropin receptor ectodomain. Involvement of a matrix metalloprotease. J. Biol. Chem. 89, 3765-3769.
    • (1996) J. Biol. Chem. , vol.89 , pp. 3765-3769
    • Couët, J.1    Sar, S.2    Jolivet, A.3    Vu Hai, M.T.4    Milgrom, E.5    Misrahi, M.6
  • 34
    • 0028877877 scopus 로고
    • Human autoantibodies to the thyrotropin receptor: Recognition of linear, folded, and glycosylated recombinant extracellular domain
    • 34. Vlase, H., Graves, P.N., Magnusson, R.P. & Davies, T.F. (1995) Human autoantibodies to the thyrotropin receptor: Recognition of linear, folded, and glycosylated recombinant extracellular domain. J. Clin. Endocrinol. Metab. 80, 46-53.
    • (1995) J. Clin. Endocrinol. Metab. , vol.80 , pp. 46-53
    • Vlase, H.1    Graves, P.N.2    Magnusson, R.P.3    Davies, T.F.4
  • 35
    • 0029895627 scopus 로고    scopus 로고
    • Critical relationship between autoantibody recognition and thyrotropin receptor maturation as reflected in the acquisition of complex carbohydrate
    • 35. Rapoport, B., McLachlan, S.M., Kakinuma, A. & Chazenbalk, G.D. (1996) Critical relationship between autoantibody recognition and thyrotropin receptor maturation as reflected in the acquisition of complex carbohydrate. J. Clin. Endocrinol. Metab. 81, 2525-2533.
    • (1996) J. Clin. Endocrinol. Metab. , vol.81 , pp. 2525-2533
    • Rapoport, B.1    McLachlan, S.M.2    Kakinuma, A.3    Chazenbalk, G.D.4
  • 36
    • 0030951081 scopus 로고    scopus 로고
    • Differential reactivities of recombinant glycosylated ectodomains of mouse and human thyrotropin receptors with patient autoantibodies
    • 36. Patibandla, S.A., Seetharamaiah, G.S., Dallas, J.S., Thotakura, N.R., Peake, R.L. & Prabhakar, B.S. (1997) Differential reactivities of recombinant glycosylated ectodomains of mouse and human thyrotropin receptors with patient autoantibodies. Endocrinology 138, 1559-1566.
    • (1997) Endocrinology , vol.138 , pp. 1559-1566
    • Patibandla, S.A.1    Seetharamaiah, G.S.2    Dallas, J.S.3    Thotakura, N.R.4    Peake, R.L.5    Prabhakar, B.S.6
  • 37
    • 0031569117 scopus 로고    scopus 로고
    • Requirement of glycosylation of the human thyrotropin receptor ectodomain for its reactivity with autoantibodies in patients' sera
    • 37. Seetharamaiah, G.S., Dallas, J.S., Patibandla, S.A., Thotakura, N.R. & Prabhakar, B.S. (1997) Requirement of glycosylation of the human thyrotropin receptor ectodomain for its reactivity with autoantibodies in patients' sera. J. Immunol. 158, 2798-2804.
    • (1997) J. Immunol. , vol.158 , pp. 2798-2804
    • Seetharamaiah, G.S.1    Dallas, J.S.2    Patibandla, S.A.3    Thotakura, N.R.4    Prabhakar, B.S.5
  • 38
    • 0031013908 scopus 로고    scopus 로고
    • Measurement of antibody/antigen association rate constants in solution by a method based on the enzyme-linked immunosorbent assay
    • 38. Hardy, F., Djavadi-Ohaniance, L. & Goldberg, M.E. (1997) Measurement of antibody/antigen association rate constants in solution by a method based on the enzyme-linked immunosorbent assay. J. Immunol. Methods. 200, 155-159.
    • (1997) J. Immunol. Methods , vol.200 , pp. 155-159
    • Hardy, F.1    Djavadi-Ohaniance, L.2    Goldberg, M.E.3
  • 39
    • 0029160330 scopus 로고
    • Genetic and epitopic analysis of thyroid peroxidase (TPO) autoantibodies: Markers of the human thyroid autoimmune response
    • 39. McLachlan, S.M. & Rapoport, B. (1995) Genetic and epitopic analysis of thyroid peroxidase (TPO) autoantibodies: markers of the human thyroid autoimmune response. Clin. Exp. Immunol. 101, 200-206.
    • (1995) Clin. Exp. Immunol. , vol.101 , pp. 200-206
    • McLachlan, S.M.1    Rapoport, B.2
  • 40
    • 0029795598 scopus 로고    scopus 로고
    • Editorial: Monoclonal, human autoantibodies to the TSH receptor - The holy grail and why are we looking for it?
    • 40. McLachlan, S.M. & Rapoport. B. (1996) Editorial: monoclonal, human autoantibodies to the TSH receptor - the holy grail and why are we looking for it? J. Clin. Endocrinol. Metab. 81, 3152-3154.
    • (1996) J. Clin. Endocrinol. Metab. , vol.81 , pp. 3152-3154
    • McLachlan, S.M.1    Rapoport, B.2
  • 43
    • 0025809064 scopus 로고
    • Immunublotting for the detection of TSH receptor autoantibodies
    • 43. Leedman, P.J., Harrison, P.J. & Harrison, L.C. (1991) Immunublotting for the detection of TSH receptor autoantibodies. J. Immunol. 4, 529-542.
    • (1991) J. Immunol. , vol.4 , pp. 529-542
    • Leedman, P.J.1    Harrison, P.J.2    Harrison, L.C.3
  • 44
  • 46
    • 0031035614 scopus 로고    scopus 로고
    • Thyrotropin receptor autoantibodies in serum are present at much lower levels than thyroid peroxidase autoantibodies: Analysis by flow cytometry
    • 46. Jaume, J.C., Kakinuma, A., Chazenbalk, G.D., Rapoport, B. & McLachlan, S.M. (1997) Thyrotropin receptor autoantibodies in serum are present at much lower levels than thyroid peroxidase autoantibodies: analysis by flow cytometry. J. Clin. Endocrinol. Metab. 82, 500-507.
    • (1997) J. Clin. Endocrinol. Metab. , vol.82 , pp. 500-507
    • Jaume, J.C.1    Kakinuma, A.2    Chazenbalk, G.D.3    Rapoport, B.4    McLachlan, S.M.5
  • 47
    • 0024709815 scopus 로고
    • Molecular and genetic characteristics of pathogenic autoantibodies
    • 47. Tron, F. & Bach, J.F. (1989) Molecular and genetic characteristics of pathogenic autoantibodies. J. Autoimmun. 2, 311-320.
    • (1989) J. Autoimmun. , vol.2 , pp. 311-320
    • Tron, F.1    Bach, J.F.2
  • 48
    • 0020040257 scopus 로고
    • Naturally occuring antibodies against nine common antigens in human sera
    • 48. Guilbert, B., Dighiero, G. & Avrameas, S. (1982) Naturally occuring antibodies against nine common antigens in human sera. J. Immunol. 126, 2779-2787.
    • (1982) J. Immunol. , vol.126 , pp. 2779-2787
    • Guilbert, B.1    Dighiero, G.2    Avrameas, S.3
  • 50
    • 0024413389 scopus 로고
    • Significance of the recognition of certain antigenic regions on the human thyroglobulin molecule by natural autoantibodies from healthy subjects
    • 50. Bouanani, M., Piechaczyk, M., Pau, B. & Bastide, M. (1989) Significance of the recognition of certain antigenic regions on the human thyroglobulin molecule by natural autoantibodies from healthy subjects. J. Immunol. 143, 1129-1132.
    • (1989) J. Immunol. , vol.143 , pp. 1129-1132
    • Bouanani, M.1    Piechaczyk, M.2    Pau, B.3    Bastide, M.4
  • 51
    • 0023550720 scopus 로고
    • Intrathyroidal MHC class II antigen expression and thyroid autoimmunity
    • 51. Davies, T.F. & Piccinini, L.A. (1987) Intrathyroidal MHC class II antigen expression and thyroid autoimmunity. Endocrinol. Metab. Clin. North Am. 16, 247-268.
    • (1987) Endocrinol. Metab. Clin. North Am. , vol.16 , pp. 247-268
    • Davies, T.F.1    Piccinini, L.A.2
  • 52
    • 0025902309 scopus 로고
    • Autoimmunity causing thyroid dysfunction
    • 52. Volpé, R. (1991) Autoimmunity causing thyroid dysfunction. Endocrinol. Metab. Clin. North Am. 20, 565-587.
    • (1991) Endocrinol. Metab. Clin. North Am. , vol.20 , pp. 565-587
    • Volpé, R.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.