Intracellular entrapment of wild-type TSH receptor by oligomerization with mutants linked to dominant TSH resistance

Human Molecular Genetics

Volumn 14, Issue 20, 2005, Pages 2991-3002

  Calebiro, Davide ^a,b   de Filippis, Tiziana ^b   Lucchi, Simona ^b   Covino, Cesare ^c   Panigone, Sara ^b   Beck Peccoz, Paolo ^a,d   Dunlap, David ^c   Persani, Luca ^a,b  

^a UNIVERSITY OF MILAN   (Italy)

^b ISTITUTO AUXOLOGICO ITALIANO   (Italy)

^c SAN RAFFAELE HOSPITAL   (Italy)

^d FONDAZIONE IRCCS CA GRANDA OSPEDALE MAGGIORE POLICLINICO   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP; G PROTEIN COUPLED RECEPTOR; MUTANT PROTEIN; OLIGOMER; THYROTROPIN RECEPTOR;

ANIMAL CELL; ARTICLE; CELL MEMBRANE; CELL STRAIN COS7; CONGENITAL HYPOTHYROIDISM; CONTROLLED STUDY; DOMINANT INHERITANCE; ENDOPLASMIC RETICULUM; FAMILIAL DISEASE; FLUORESCENCE MICROSCOPY; FLUORESCENCE RESONANCE ENERGY TRANSFER; GENE FUSION; GENE MUTATION; HETEROZYGOSITY; HORMONAL REGULATION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOPRECIPITATION; MOLECULAR INTERACTION; NONHUMAN; OLIGOMERIZATION; PEDIGREE ANALYSIS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN PROCESSING; REPORTER GENE; THYROID HORMONE RESISTANCE; WILD TYPE;

ANIMALS; CELL MEMBRANE; CERCOPITHECUS AETHIOPS; COS CELLS; ENDOPLASMIC RETICULUM; GENES, DOMINANT; HETEROZYGOTE; IMMUNOPRECIPITATION; INTRACELLULAR SPACE; MUTATION; PEDIGREE; PROTEIN STRUCTURE, QUATERNARY; RECEPTORS, THYROTROPIN; THYROID HORMONE RESISTANCE SYNDROME; THYROTROPIN; TRANSFECTION;

ANIMALIA;

EID: 27544481186     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddi329     Document Type: Article

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