-
1
-
-
0035979775
-
Reversal of obesity- and diet-induced insulin resistance with salicylates or targeted disruption of IKKβ
-
Yuan M., Konstantopoulos N., and Lee J. Reversal of obesity- and diet-induced insulin resistance with salicylates or targeted disruption of IKKβ. Science 293 (2001) 1673-1677
-
(2001)
Science
, vol.293
, pp. 1673-1677
-
-
Yuan, M.1
Konstantopoulos, N.2
Lee, J.3
-
2
-
-
0035411587
-
Role of the NF-κB pathway in the pathogenesis of human disease states
-
Yamamoto Y., and Gaynor R.B. Role of the NF-κB pathway in the pathogenesis of human disease states. Curr. Mol. Med. 1 (2001) 287-296
-
(2001)
Curr. Mol. Med.
, vol.1
, pp. 287-296
-
-
Yamamoto, Y.1
Gaynor, R.B.2
-
4
-
-
0027218865
-
Interaction between glucose and free fatty acid metabolism in human skeletal muscle
-
Kelley D.E., Mokan M., Simoneau J.A., and Mandarino L.J. Interaction between glucose and free fatty acid metabolism in human skeletal muscle. J. Clin. Invest. 92 (1993) 91-98
-
(1993)
J. Clin. Invest.
, vol.92
, pp. 91-98
-
-
Kelley, D.E.1
Mokan, M.2
Simoneau, J.A.3
Mandarino, L.J.4
-
5
-
-
0028342686
-
Mechanisms of fatty acid-induced inhibition of glucose uptake
-
Boden G., Chen X., Ruiz J., White J.V., and Rossetti L. Mechanisms of fatty acid-induced inhibition of glucose uptake. J. Clin. Invest. 93 (1994) 2438-2446
-
(1994)
J. Clin. Invest.
, vol.93
, pp. 2438-2446
-
-
Boden, G.1
Chen, X.2
Ruiz, J.3
White, J.V.4
Rossetti, L.5
-
6
-
-
0033927667
-
Cellular mechanisms of insulin resistance
-
Shulman G.I. Cellular mechanisms of insulin resistance. J. Clin. Invest. 106 (2000) 171-176
-
(2000)
J. Clin. Invest.
, vol.106
, pp. 171-176
-
-
Shulman, G.I.1
-
7
-
-
0034611791
-
Obesity as a medical problem
-
Kopelman P.G. Obesity as a medical problem. Nature 404 (2000) 635-643
-
(2000)
Nature
, vol.404
, pp. 635-643
-
-
Kopelman, P.G.1
-
8
-
-
0037184925
-
Mechanisms by which fatty acids inhibit insulin activation of insulin receptor substrate-1 (IRS-1)-associated phosphatidylinositol 3-kinase activity in muscle
-
Yu C., Chen Y., Cline G.W., Zhang D., Zong H., Wang Y., Bergeron R., Kim J.K., Cushman S.W., Cooney G.J., Atcheson B., White M.F., Kraegen E.W., and Shulman G.I. Mechanisms by which fatty acids inhibit insulin activation of insulin receptor substrate-1 (IRS-1)-associated phosphatidylinositol 3-kinase activity in muscle. J. Biol. Chem. 27 (2002) 50230-50236
-
(2002)
J. Biol. Chem.
, vol.27
, pp. 50230-50236
-
-
Yu, C.1
Chen, Y.2
Cline, G.W.3
Zhang, D.4
Zong, H.5
Wang, Y.6
Bergeron, R.7
Kim, J.K.8
Cushman, S.W.9
Cooney, G.J.10
Atcheson, B.11
White, M.F.12
Kraegen, E.W.13
Shulman, G.I.14
-
9
-
-
0032954778
-
Effects of free fatty acids on glucose transport and IRS-1-associated phosphatidylinositol 3-kinase activity
-
Dresner A., Laurent D., Marcucci M., Griffin M.E., Dufour S., Cline G.W., Slezak L.A., Andersen D.K., Hundal R.S., Rothman D.L., Petersen K.F., and Shulman G.I. Effects of free fatty acids on glucose transport and IRS-1-associated phosphatidylinositol 3-kinase activity. J. Clin. Invest. 103 (1999) 253-259
-
(1999)
J. Clin. Invest.
, vol.103
, pp. 253-259
-
-
Dresner, A.1
Laurent, D.2
Marcucci, M.3
Griffin, M.E.4
Dufour, S.5
Cline, G.W.6
Slezak, L.A.7
Andersen, D.K.8
Hundal, R.S.9
Rothman, D.L.10
Petersen, K.F.11
Shulman, G.I.12
-
10
-
-
0030969532
-
Skeletal muscle triglyceride levels are inversely related to insulin action
-
Pan D.A., Lillioja S., Kriketos A.D., Milner M.R., Baur L.A., Bogardus C., Jenkins A.B., and Storlien L.H. Skeletal muscle triglyceride levels are inversely related to insulin action. Diabetes 46 (1997) 983-988
-
(1997)
Diabetes
, vol.46
, pp. 983-988
-
-
Pan, D.A.1
Lillioja, S.2
Kriketos, A.D.3
Milner, M.R.4
Baur, L.A.5
Bogardus, C.6
Jenkins, A.B.7
Storlien, L.H.8
-
11
-
-
0035405847
-
Effect of acute changes of plasma free fatty acids on intramyocellular fat content and insulin resistance in healthy subjects
-
Boden G., Lebed B., Schatz M., Homko C., and Lemieux S. Effect of acute changes of plasma free fatty acids on intramyocellular fat content and insulin resistance in healthy subjects. Diabetes 50 (2001) 1612-1617
-
(2001)
Diabetes
, vol.50
, pp. 1612-1617
-
-
Boden, G.1
Lebed, B.2
Schatz, M.3
Homko, C.4
Lemieux, S.5
-
12
-
-
0031753812
-
Five-hour fatty acid elevation increases muscle lipids and impairs glycogen synthesis in the rat
-
Chalkley S.M., Hettiarachchi M., Chisholm D.J., and Kraegen E.W. Five-hour fatty acid elevation increases muscle lipids and impairs glycogen synthesis in the rat. Metabolism 47 (1998) 1121-1126
-
(1998)
Metabolism
, vol.47
, pp. 1121-1126
-
-
Chalkley, S.M.1
Hettiarachchi, M.2
Chisholm, D.J.3
Kraegen, E.W.4
-
13
-
-
0345086474
-
Free fatty acid-induced insulin resistance is associated with activation of protein kinase C theta and alterations in the insulin signaling cascade
-
Griffin M.E., Marcucci M.J., Cline G.W., Bell K., Barucci N., Lee D., Goodyear L.J., Kraegen E.W., White M.F., and Shulman G.I. Free fatty acid-induced insulin resistance is associated with activation of protein kinase C theta and alterations in the insulin signaling cascade. Diabetes 48 (1999) 1270-1274
-
(1999)
Diabetes
, vol.48
, pp. 1270-1274
-
-
Griffin, M.E.1
Marcucci, M.J.2
Cline, G.W.3
Bell, K.4
Barucci, N.5
Lee, D.6
Goodyear, L.J.7
Kraegen, E.W.8
White, M.F.9
Shulman, G.I.10
-
14
-
-
0036300538
-
Lipid-induced insulin resistance in human muscle is associated with changes in diacylglycerol, protein kinase C, and IκBα
-
Itani S.I., Ruderman N.B., Schmieder F., and Boden G. Lipid-induced insulin resistance in human muscle is associated with changes in diacylglycerol, protein kinase C, and IκBα. Diabetes 51 (2002) 2005-2011
-
(2002)
Diabetes
, vol.51
, pp. 2005-2011
-
-
Itani, S.I.1
Ruderman, N.B.2
Schmieder, F.3
Boden, G.4
-
15
-
-
0031014830
-
Role of fatty acids in the pathogenesis of insulin resistance and NIDDM
-
Boden G. Role of fatty acids in the pathogenesis of insulin resistance and NIDDM. Diabetes 46 (1997) 3-10
-
(1997)
Diabetes
, vol.46
, pp. 3-10
-
-
Boden, G.1
-
16
-
-
8844255630
-
Free fatty acids in obesity and type2 diabetes: defining their role in the development of insulin resistance and beta-cell dysfunction
-
Boden G., and Shulman G.I. Free fatty acids in obesity and type2 diabetes: defining their role in the development of insulin resistance and beta-cell dysfunction. Eur. J. Clin. Invest. 32 (2002) 14-23
-
(2002)
Eur. J. Clin. Invest.
, vol.32
, pp. 14-23
-
-
Boden, G.1
Shulman, G.I.2
-
17
-
-
0035857020
-
New drug targets for type 2 diabetes and the metabolic syndrome
-
Moller D.E. New drug targets for type 2 diabetes and the metabolic syndrome. Nature 414 (2002) 821-827
-
(2002)
Nature
, vol.414
, pp. 821-827
-
-
Moller, D.E.1
-
18
-
-
0032829745
-
Overnight lowering of free fatty acids with Acipimox improves insulin resistance and glucose tolerance in obese diabetic and nondiabetic subjects
-
Santomauro A.T., Boden G., Silva M.E., Rocha D.M., Santos R.F., Ursich M.J., Strassmann P.G., and Wajchenburg B.L. Overnight lowering of free fatty acids with Acipimox improves insulin resistance and glucose tolerance in obese diabetic and nondiabetic subjects. Diabetes 48 (1999) 1836-1841
-
(1999)
Diabetes
, vol.48
, pp. 1836-1841
-
-
Santomauro, A.T.1
Boden, G.2
Silva, M.E.3
Rocha, D.M.4
Santos, R.F.5
Ursich, M.J.6
Strassmann, P.G.7
Wajchenburg, B.L.8
-
19
-
-
0036099857
-
Mechanism by which high-dose aspirin improves glucose metabolism in type 2 diabetes
-
Hundal R.S., Petersen K.F., Mayerson A.B., Randhawa P.S., Inzucchi S., Shoelson S.E., and Shulman G.I. Mechanism by which high-dose aspirin improves glucose metabolism in type 2 diabetes. J. Clin. Invest. 10 (2002) 1321-1326
-
(2002)
J. Clin. Invest.
, vol.10
, pp. 1321-1326
-
-
Hundal, R.S.1
Petersen, K.F.2
Mayerson, A.B.3
Randhawa, P.S.4
Inzucchi, S.5
Shoelson, S.E.6
Shulman, G.I.7
-
20
-
-
0034903710
-
Prevention of fat-induced insulin resistance by salicylate
-
Kim J.K., Kim Y.J., Fillmore J.J., Chen Y., Moore I., Lee J.S., Yuan M.S., Li Z.W., Karin M., Perret P., Shoelson S.E., and Shulman G.I. Prevention of fat-induced insulin resistance by salicylate. J. Clin. Invest. 108 (2001) 437-446
-
(2001)
J. Clin. Invest.
, vol.108
, pp. 437-446
-
-
Kim, J.K.1
Kim, Y.J.2
Fillmore, J.J.3
Chen, Y.4
Moore, I.5
Lee, J.S.6
Yuan, M.S.7
Li, Z.W.8
Karin, M.9
Perret, P.10
Shoelson, S.E.11
Shulman, G.I.12
-
21
-
-
4744344777
-
Fatty acid-induced insulin resistance in L6 myotubes is prevented by inhibition of activation and nuclear localization of Nuclear Factor κB
-
Sinha S., Perdomo G., Brown N.F., and O'Doherty R.M. Fatty acid-induced insulin resistance in L6 myotubes is prevented by inhibition of activation and nuclear localization of Nuclear Factor κB. J. Biol. Chem. 279 (2004) 41294-41301
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 41294-41301
-
-
Sinha, S.1
Perdomo, G.2
Brown, N.F.3
O'Doherty, R.M.4
-
22
-
-
14644427890
-
Local and systemic insulin resistance resulting from hepatic activation of IKK-β and NF-κB
-
Cai D., Yuan M., Frantz D.F., Melendez P.A., Hansen L., Lee J., and Shoelson S.E. Local and systemic insulin resistance resulting from hepatic activation of IKK-β and NF-κB. Nat. Med. 11 (2005) 183-190
-
(2005)
Nat. Med.
, vol.11
, pp. 183-190
-
-
Cai, D.1
Yuan, M.2
Frantz, D.F.3
Melendez, P.A.4
Hansen, L.5
Lee, J.6
Shoelson, S.E.7
-
23
-
-
33751163999
-
The NF-κB pathway
-
Moynagh P.N. The NF-κB pathway. J. Cell Sci. 118 (2005) 4389-4392
-
(2005)
J. Cell Sci.
, vol.118
, pp. 4389-4392
-
-
Moynagh, P.N.1
-
24
-
-
24944473034
-
NF-κB controls the global proinflammatory response in endothelial cells: evidence for the regulation of a pro-atherogenic program
-
Kempe S., Kestler H., Lasar A., and Wirth T. NF-κB controls the global proinflammatory response in endothelial cells: evidence for the regulation of a pro-atherogenic program. Nucleic Acids Res. 33 (2005) 165308-165319
-
(2005)
Nucleic Acids Res.
, vol.33
, pp. 165308-165319
-
-
Kempe, S.1
Kestler, H.2
Lasar, A.3
Wirth, T.4
-
25
-
-
1842526076
-
Active repression of antiapoptotic gene expression by RelA(p65) NF-κB
-
Campbell J.K., Rocha S., and Perkins D.N. Active repression of antiapoptotic gene expression by RelA(p65) NF-κB. Mol. Cell 13 (2004) 853-865
-
(2004)
Mol. Cell
, vol.13
, pp. 853-865
-
-
Campbell, J.K.1
Rocha, S.2
Perkins, D.N.3
-
26
-
-
29044447292
-
Free fatty acids produce insulin resistance and activate the proinflammatory Nuclear Factor-κB pathway in rat liver
-
Boden G., She P., Mozzoli M., Cheung P., Gumireddy K., Reddy P., Xiang X., Luo Z., and Ruderman N. Free fatty acids produce insulin resistance and activate the proinflammatory Nuclear Factor-κB pathway in rat liver. Diabetes 54 (2005) 3458-3465
-
(2005)
Diabetes
, vol.54
, pp. 3458-3465
-
-
Boden, G.1
She, P.2
Mozzoli, M.3
Cheung, P.4
Gumireddy, K.5
Reddy, P.6
Xiang, X.7
Luo, Z.8
Ruderman, N.9
-
27
-
-
33644680390
-
Conjugated linoleic acid promotes human adipocyte insulin resistance through NFκB-dependent cytokine production
-
Chung S., Brown J.M., Provo J.N., Hopkins R., and Mclntosh M.K. Conjugated linoleic acid promotes human adipocyte insulin resistance through NFκB-dependent cytokine production. J. Biol. Chem. 280 (2005) 38445-38456
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 38445-38456
-
-
Chung, S.1
Brown, J.M.2
Provo, J.N.3
Hopkins, R.4
Mclntosh, M.K.5
-
28
-
-
22144498471
-
Palmitate-induced interleukin 6 production is mediated by protein kinase C and Nuclear-factor κB activation and leads to Glucose transporter 4 down-regulation in skeletal muscle cells
-
Jove M., Planavila A., Laguna J.C., and Vazquez-Carrera M. Palmitate-induced interleukin 6 production is mediated by protein kinase C and Nuclear-factor κB activation and leads to Glucose transporter 4 down-regulation in skeletal muscle cells. Endocrinology 146 (2005) 3087-3095
-
(2005)
Endocrinology
, vol.146
, pp. 3087-3095
-
-
Jove, M.1
Planavila, A.2
Laguna, J.C.3
Vazquez-Carrera, M.4
-
29
-
-
0033710929
-
PKCe{open} modulates NF-κB and AP-1 via mitogen-activated protein kinases in adult rabbit cardiomyocytes
-
Li R.C., Ping P., Zhang J., Wead W.B., Cao X., Gao J., Zheng Y., Huang S., Han J., and Bolli R. PKCe{open} modulates NF-κB and AP-1 via mitogen-activated protein kinases in adult rabbit cardiomyocytes. Am. J. Physiol. Heart Circ. Physiol 279 (2000) H1679-H1689
-
(2000)
Am. J. Physiol. Heart Circ. Physiol
, vol.279
-
-
Li, R.C.1
Ping, P.2
Zhang, J.3
Wead, W.B.4
Cao, X.5
Gao, J.6
Zheng, Y.7
Huang, S.8
Han, J.9
Bolli, R.10
-
30
-
-
33746784110
-
Ethanol sensitizes NF-κB in pancreatic acinar cells through effects on protein kinase C-e{open}
-
Satoh A., Gukovskaya A.S., Reeve Jr. J.R., Shimosegawa T., and Pandol S.J. Ethanol sensitizes NF-κB in pancreatic acinar cells through effects on protein kinase C-e{open}. Am. J. Physiol. Gastrointest. Liver Physiol. 291 (2006) G432-G438
-
(2006)
Am. J. Physiol. Gastrointest. Liver Physiol.
, vol.291
-
-
Satoh, A.1
Gukovskaya, A.S.2
Reeve Jr., J.R.3
Shimosegawa, T.4
Pandol, S.J.5
-
31
-
-
32544432975
-
Involvement of PKC isoforms in FFA induced defects in insulin signaling
-
Dey D., Basu D., Roy S.S., Bandyopadhyay A., and Bhattacharya S. Involvement of PKC isoforms in FFA induced defects in insulin signaling. Mol. Cell. Endocrinol. 246 (2006) 60-64
-
(2006)
Mol. Cell. Endocrinol.
, vol.246
, pp. 60-64
-
-
Dey, D.1
Basu, D.2
Roy, S.S.3
Bandyopadhyay, A.4
Bhattacharya, S.5
-
32
-
-
27844520859
-
Inhibition of insulin receptor gene expression and insulin signaling by fatty acid: interplay of PKC isoforms therein
-
Dey D., Mukherjee M., Basu D., Datta M., Roy S.S., Bandyopadhyay A., and Bhattacharya S. Inhibition of insulin receptor gene expression and insulin signaling by fatty acid: interplay of PKC isoforms therein. Cell Physiol. Biochem. 16 (2005) 217-228
-
(2005)
Cell Physiol. Biochem.
, vol.16
, pp. 217-228
-
-
Dey, D.1
Mukherjee, M.2
Basu, D.3
Datta, M.4
Roy, S.S.5
Bandyopadhyay, A.6
Bhattacharya, S.7
-
33
-
-
34247382539
-
Fatty acid represses insulin receptor gene expression by impairing HMGA1 through protein kinase Ce{open}
-
Dey D., Bhattacharya A., Roy S.S., and Bhattacharya S. Fatty acid represses insulin receptor gene expression by impairing HMGA1 through protein kinase Ce{open}. Biochem. Biophys. Res. Commun. 357 (2007) 474-479
-
(2007)
Biochem. Biophys. Res. Commun.
, vol.357
, pp. 474-479
-
-
Dey, D.1
Bhattacharya, A.2
Roy, S.S.3
Bhattacharya, S.4
-
35
-
-
34250014758
-
A Lupinoside prevented fatty acid induced inhibition of insulin sensitivity in 3T3 L1 adipocytes
-
Dey D., Pal B.C., Biswas T., Roy S.S., Bandyopadhyay A., Mandal S.K., Giri B.B., and Bhattacharya S. A Lupinoside prevented fatty acid induced inhibition of insulin sensitivity in 3T3 L1 adipocytes. Mol. Cell Biochem. 300 (2007) 149-157
-
(2007)
Mol. Cell Biochem.
, vol.300
, pp. 149-157
-
-
Dey, D.1
Pal, B.C.2
Biswas, T.3
Roy, S.S.4
Bandyopadhyay, A.5
Mandal, S.K.6
Giri, B.B.7
Bhattacharya, S.8
-
36
-
-
0037238183
-
Purification of two types of gonadotropin receptors from carp ovarian follicles: overlapping recognition by two different ligands
-
Basu D., and Bhattacharya S. Purification of two types of gonadotropin receptors from carp ovarian follicles: overlapping recognition by two different ligands. Gen. Comp. Endo. 129 (2002) 152-162
-
(2002)
Gen. Comp. Endo.
, vol.129
, pp. 152-162
-
-
Basu, D.1
Bhattacharya, S.2
-
37
-
-
0021100690
-
Accurate transcription initiation by RNA polymerase D in a soluble extract from isolated mammalian nuclei
-
Dignam J.D., Lebovitz R.M., and Roeder R.G. Accurate transcription initiation by RNA polymerase D in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res. 11 (1983) 1475-1489
-
(1983)
Nucleic Acids Res.
, vol.11
, pp. 1475-1489
-
-
Dignam, J.D.1
Lebovitz, R.M.2
Roeder, R.G.3
-
38
-
-
0345873536
-
Delivery of bioactive, gel-isolated proteins into live cells
-
Taylor J.E., and Patron C.F. Delivery of bioactive, gel-isolated proteins into live cells. Electrophoresis 24 (2003) 1331-1337
-
(2003)
Electrophoresis
, vol.24
, pp. 1331-1337
-
-
Taylor, J.E.1
Patron, C.F.2
-
39
-
-
0036566148
-
Regulation of novel protein kinase Ce{open} by phosphorylation
-
Cenni V., Doppler H., Sonnemburg E.D., Maraldi N., Newton A.C., and Toker A. Regulation of novel protein kinase Ce{open} by phosphorylation. Biochem. J. 363 (2002) 537-545
-
(2002)
Biochem. J.
, vol.363
, pp. 537-545
-
-
Cenni, V.1
Doppler, H.2
Sonnemburg, E.D.3
Maraldi, N.4
Newton, A.C.5
Toker, A.6
-
40
-
-
21744448372
-
n3 PUFA's modulate T-cell activation via protein kinase C-α and -e{open} and NF-κB signaling pathway
-
Denys A., Hicham A., and Khan N.A. n3 PUFA's modulate T-cell activation via protein kinase C-α and -e{open} and NF-κB signaling pathway. J. Lipid Res. 46 (2005) 752-758
-
(2005)
J. Lipid Res.
, vol.46
, pp. 752-758
-
-
Denys, A.1
Hicham, A.2
Khan, N.A.3
-
41
-
-
0033588253
-
Ceramide generation is sufficient to account for the inhibition of the insulin-stimulated PKB pathway in C2C12 skeletal muscle cells pretreated with palmitate
-
Schmitz-Peiffer C., Craig D.L., and Biden T.J. Ceramide generation is sufficient to account for the inhibition of the insulin-stimulated PKB pathway in C2C12 skeletal muscle cells pretreated with palmitate. J. Biol. Chem. 274 (1999) 24202-24210
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 24202-24210
-
-
Schmitz-Peiffer, C.1
Craig, D.L.2
Biden, T.J.3
-
42
-
-
33748755008
-
Toll-like receptor-2 is essential for the development of palmitate-induced insulin resistance in myotubes
-
Senn J.J. Toll-like receptor-2 is essential for the development of palmitate-induced insulin resistance in myotubes. J. Biol. Chem. 281 (2006) 26865-26875
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 26865-26875
-
-
Senn, J.J.1
-
43
-
-
0038532298
-
A role for ceramide, but not diacylglycerol, in the antagonism of insulin signal transduction by saturated fatty acids
-
Chavez J.A., Knotts T.A., Wang L.P., Li G., Dobrowsky R.T., Florant G.L., and Summers S.A. A role for ceramide, but not diacylglycerol, in the antagonism of insulin signal transduction by saturated fatty acids. J. Biol. Chem. 278 (2003) 10297-10303
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 10297-10303
-
-
Chavez, J.A.1
Knotts, T.A.2
Wang, L.P.3
Li, G.4
Dobrowsky, R.T.5
Florant, G.L.6
Summers, S.A.7
-
44
-
-
0034523132
-
+ thymocytes correlates with negative selection
-
+ thymocytes correlates with negative selection. Cell Death Differ. 7 (2000) 1253-1262
-
(2000)
Cell Death Differ.
, vol.7
, pp. 1253-1262
-
-
Simon, A.K.1
Auphan, N.2
Pophillat, M.3
Boyer, C.4
Ghosh, S.5
Rincon, M.6
Flavell, R.A.7
Schmitt-Verhulst, A.-M.8
-
45
-
-
0036234459
-
Missing pieces in the NF-κB puzzle
-
Ghosh S., and Karin M. Missing pieces in the NF-κB puzzle. Cell 109 (2002) 81-96
-
(2002)
Cell
, vol.109
, pp. 81-96
-
-
Ghosh, S.1
Karin, M.2
-
46
-
-
33847404482
-
Inhibition of protein kinase Ce{open} prevents hepatic insulin resistance in nonalcoholic fatty liver disease
-
Samuel V.T., Liu Z.X., Wang A., Beddow S.A., Geisler J.G., Kahn M., Zhang X., Monia B.P., Bhanot S., and Shulman G.I. Inhibition of protein kinase Ce{open} prevents hepatic insulin resistance in nonalcoholic fatty liver disease. J. Clin. Invest 117 (2007) 739-745
-
(2007)
J. Clin. Invest
, vol.117
, pp. 739-745
-
-
Samuel, V.T.1
Liu, Z.X.2
Wang, A.3
Beddow, S.A.4
Geisler, J.G.5
Kahn, M.6
Zhang, X.7
Monia, B.P.8
Bhanot, S.9
Shulman, G.I.10
-
47
-
-
0030991201
-
The transcriptional activity of NF-Kappa B p65 is regulated by the I-Kappa B associated PKA C subunit through a cyclic-AMP independent mechanism
-
Zhong H., SuYang H., Erdjument-Bromage H., Tempst P., and Ghosh S. The transcriptional activity of NF-Kappa B p65 is regulated by the I-Kappa B associated PKA C subunit through a cyclic-AMP independent mechanism. Cell 89 (1997) 413-424
-
(1997)
Cell
, vol.89
, pp. 413-424
-
-
Zhong, H.1
SuYang, H.2
Erdjument-Bromage, H.3
Tempst, P.4
Ghosh, S.5
-
48
-
-
0032039076
-
Phosphorylation of NF-Kappa B p65 by PKA stimulates transcriptional activity by promoting a novel bivalent interaction with the co-activator CBP/P300
-
Zhong H., Voll R..E., and Ghosh S. Phosphorylation of NF-Kappa B p65 by PKA stimulates transcriptional activity by promoting a novel bivalent interaction with the co-activator CBP/P300. Mol. Cell. 1 (1998) 661-671
-
(1998)
Mol. Cell.
, vol.1
, pp. 661-671
-
-
Zhong, H.1
Voll, R..E.2
Ghosh, S.3
-
49
-
-
2442572230
-
Identification of a p65 peptide that selectively inhibits NF-κB activation induced by various inflammatory stimuli and its role in downregulation of NF-κB-mediated gene expression and up-regulation of apoptosis
-
Takada Y., Singh S., and Aggarwal B.B. Identification of a p65 peptide that selectively inhibits NF-κB activation induced by various inflammatory stimuli and its role in downregulation of NF-κB-mediated gene expression and up-regulation of apoptosis. J. Biol. Chem. 279 (2004) 15096-15104
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 15096-15104
-
-
Takada, Y.1
Singh, S.2
Aggarwal, B.B.3
-
50
-
-
0031437893
-
Activation of nuclear transcription factor NF-κB by interleukin-1 is accompanied by casein kinase II-mediated phosphorylation of p65 subunit
-
Bird T.A., Schooley K., Dower S.K., Hagen H., and Virca G.D. Activation of nuclear transcription factor NF-κB by interleukin-1 is accompanied by casein kinase II-mediated phosphorylation of p65 subunit. J. Biol. Chem. 272 (1997) 32606-32612
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 32606-32612
-
-
Bird, T.A.1
Schooley, K.2
Dower, S.K.3
Hagen, H.4
Virca, G.D.5
-
51
-
-
0034693133
-
Tumor necrosis factor alpha induced phosphorylation of RelA/p65 on Ser529 is controlled by casein kinase II
-
Wang D., Westerheide S.D., Hanson J.L., and Baldwin Jr. A.S. Tumor necrosis factor alpha induced phosphorylation of RelA/p65 on Ser529 is controlled by casein kinase II. J. Biol. Chem. 275 (2000) 32592-32597
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 32592-32597
-
-
Wang, D.1
Westerheide, S.D.2
Hanson, J.L.3
Baldwin Jr., A.S.4
-
52
-
-
0032491485
-
Tumor necrosis factor-dependent activation of a RelA homodimer in astrocytes
-
Wang D., and Baldwin Jr. A.S. Tumor necrosis factor-dependent activation of a RelA homodimer in astrocytes. J. Biol. Chem. 273 (1998) 29411-29416
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 29411-29416
-
-
Wang, D.1
Baldwin Jr., A.S.2
-
53
-
-
0037432593
-
Oleic acid induces endothelin-1 expression through activation of protein kinase C and NF-κB
-
Park J.-Y., Kim Y.M., Song H.S., Park K.Y., Kim Y.M., Kim M.S., Pak Y.K., Lee I.K., Lee J.D., Park S.-J., and Lee K.-U. Oleic acid induces endothelin-1 expression through activation of protein kinase C and NF-κB. Biochem. Biophys. Res. Commun. 303 (2003) 891-895
-
(2003)
Biochem. Biophys. Res. Commun.
, vol.303
, pp. 891-895
-
-
Park, J.-Y.1
Kim, Y.M.2
Song, H.S.3
Park, K.Y.4
Kim, Y.M.5
Kim, M.S.6
Pak, Y.K.7
Lee, I.K.8
Lee, J.D.9
Park, S.-J.10
Lee, K.-U.11
-
54
-
-
0028911139
-
Analysis of the role of protein kinase C-α, -e{open} and -ζ in T cell activation
-
Genot E.M., Parker P.J., and Cantrell D.A. Analysis of the role of protein kinase C-α, -e{open} and -ζ in T cell activation. J. Biol. Chem. 270 (1995) 9833-9839
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 9833-9839
-
-
Genot, E.M.1
Parker, P.J.2
Cantrell, D.A.3
-
55
-
-
0033710929
-
PKCe{open} modulates NF-κB and AP-1 via mitogen-activated protein kinases in adult rabbit cardiomyocytes
-
Li R.C.X., Ping P., Zhang J., Wead W.B., Cao X., Gao J., Zhang Y., Huang S., Han J., and Bolli R. PKCe{open} modulates NF-κB and AP-1 via mitogen-activated protein kinases in adult rabbit cardiomyocytes. Am. J. Physiol. Heart Circ. Physiol 279 (2000) 1679-1689
-
(2000)
Am. J. Physiol. Heart Circ. Physiol
, vol.279
, pp. 1679-1689
-
-
Li, R.C.X.1
Ping, P.2
Zhang, J.3
Wead, W.B.4
Cao, X.5
Gao, J.6
Zhang, Y.7
Huang, S.8
Han, J.9
Bolli, R.10
-
56
-
-
4444260453
-
PKC-δ and -e{open} regulates NF-κB activation induced by cholecystokinin and TNF-α in pancreatic acinar cells
-
Satoh A., Gukovskaya A.S., Nieto J.M., Cheng J.H., Gukovsky I., Reeve Jr. J.R., Shimosegawa T., and Pandol S.J. PKC-δ and -e{open} regulates NF-κB activation induced by cholecystokinin and TNF-α in pancreatic acinar cells. Am. J. Physiol. Gastrointest. Liver Physiol. 287 (2004) 582-591
-
(2004)
Am. J. Physiol. Gastrointest. Liver Physiol.
, vol.287
, pp. 582-591
-
-
Satoh, A.1
Gukovskaya, A.S.2
Nieto, J.M.3
Cheng, J.H.4
Gukovsky, I.5
Reeve Jr., J.R.6
Shimosegawa, T.7
Pandol, S.J.8
-
57
-
-
20444494359
-
A novel protein kinase C (PKCe{open}) is required for fMet-Leu-Phe-induced activation of NF-κB in human peripheral blood monocytes
-
Chen L.-Yu., Doerner A., Lehmann P.F., Huang S., Zhong G., and Pan Z.K. A novel protein kinase C (PKCe{open}) is required for fMet-Leu-Phe-induced activation of NF-κB in human peripheral blood monocytes. J. Biol. Chem. 280 (2005) 22497-22501
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 22497-22501
-
-
Chen, L.-Yu.1
Doerner, A.2
Lehmann, P.F.3
Huang, S.4
Zhong, G.5
Pan, Z.K.6
-
58
-
-
0027462682
-
Mutual regulation of the transcriptional activator NF-kappa B and its inhibitor I kappa B-alpha
-
Brown K., Park S., Kanno T., Franzoso G., and Siebenlist U. Mutual regulation of the transcriptional activator NF-kappa B and its inhibitor I kappa B-alpha. Proc. Nat. Aca. Sci. U. S. A. 90 (1993) 2532-2536
-
(1993)
Proc. Nat. Aca. Sci. U. S. A.
, vol.90
, pp. 2532-2536
-
-
Brown, K.1
Park, S.2
Kanno, T.3
Franzoso, G.4
Siebenlist, U.5
-
59
-
-
0011321375
-
Glutathione downregulates the phosphorylation of IkB: autoloop regulation of the NF-κB-mediated expression of NF-κB subunits by TNF-α in mouse muscular endothelial cells
-
Cho S., Urata Y., Iida T., Goto S., Yamaguchi M., Sumikawa K., and Kondo T. Glutathione downregulates the phosphorylation of IkB: autoloop regulation of the NF-κB-mediated expression of NF-κB subunits by TNF-α in mouse muscular endothelial cells. Biochem. Biophys. Res. Commun. 253 (1998) 104-108
-
(1998)
Biochem. Biophys. Res. Commun.
, vol.253
, pp. 104-108
-
-
Cho, S.1
Urata, Y.2
Iida, T.3
Goto, S.4
Yamaguchi, M.5
Sumikawa, K.6
Kondo, T.7
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