PKCε modulates NF-κB and AP-1 via mitogen-activated protein kinases in adult rabbit cardiomyocytes

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 279, Issue 4 48-4, 2000, Pages

  Li, Richard C X ^a   Ping, Peipei ^a   Zhang, Jun ^a   Wead, William B ^a   Cao, Xinan ^a   Gao, Jiuming ^a   Zheng, Yuting ^a   Huang, Shuang ^b   Han, Jiahuai ^b   Bolli, Roberto ^a  

^a University of Louisville School of Medicine   (United States)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

Activator protein 1; Nuclear factor B; Protein kinase C

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; PROTEIN KINASE C; DNA; ISOENZYME; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN C JUN; PROTEIN KINASE C EPSILON; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR AP 1;

ANIMAL CELL; ARTICLE; ENZYME ACTIVATION; ENZYME ACTIVITY; HEART HEMODYNAMICS; HEART MUSCLE CELL; NONHUMAN; PRIORITY JOURNAL; RABBIT; SIGNAL TRANSDUCTION; ANIMAL; CELL CULTURE; CELL NUCLEUS; CYTOLOGY; HEART MUSCLE; METABOLISM; PHYSIOLOGY;

ANIMALS; CELL NUCLEUS; CELLS, CULTURED; DNA; ENZYME ACTIVATION; ISOENZYMES; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASES; MYOCARDIUM; NF-KAPPA B; PROTEIN KINASE C; PROTEIN KINASE C-EPSILON; PROTO-ONCOGENE PROTEINS C-JUN; RABBITS; TRANSCRIPTION FACTOR AP-1;

EID: 0033710929     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.2000.279.4.h1679     Document Type: Article

References (53)

1. NF-κB: Ten years after
2. Evidence for a role of MEK and MAPK during signal transduction by protein kinase Cζ
3. Evidence that interleukin-1 and phorbol esters activate NF-κB by different pathways: Role of protein kinase C
4. Role of the protein kinase C λ/ι isoform in nuclear factor-κB activation by interleukin-1β or tumor necrosis factor-α: Cell type specificities
5. Induction of nuclear factor-κB and activation of protein 1 in postischemic myocardium
6. Modulation of MAP kinase signaling and growth characteristics by the overexpression of protein kinase C in NIH 3T3 cells
7. Kainate receptors activate NF-κB via MAP kinase in striatal neurones
8. Epithelial injury induces Egr- 1 and Fos expression by a pathway involving protein kinase C and ERK
9. Expression of v-src in T cells correlates with nuclear expression of NF-κB
10. Protein kinase Cζ mediates NF-κB activation in human immunodeficiency virus-infected monocytes
11. Stress-activated protein kinases in cardiovascular disease
12. A Mycoplasma fermentans-derived synthetic lipopeptide induces AP-1 and NF-κB activity and cytokine secretion in macrophages via the activation of mitogen-activated protein kinase pathways
13. Analysis of the role of protein kinase C-α, -ε, and -ζ in T cell activation
14. Protein kinase Cθ, a selective upstream regulator of JNK/SAPK and IL- 2 promoter activation in Jurkat T cells
15. A selective epsilon-protein C antagonist inhibits protection of cardiac myocytes from hypoxia-induced cell death
16. The late phase of ischemic preconditioning is abrogated by targeted disruption of the inducible NO synthase gene
17. Attachment and maintenance of adult rabbit cardiac myocytes in primary cell culture
18. Transcriptional regulation by extracellular signals: Mechanisms and specificity
19. A protein kinase C isozyme, nPKC ε, is involved in the activation of NF-κB by 12-O-tetradecanoylphorbol-13-acetate (TPA) in rat 3Y1 fibroblasts
20. Ischemic preconditioning increases iNOS transcript levels in conscious rabbits via a nitric oxide-dependent mechanism
21. Ras-dependent and Ras-independent activation pathways for the stress-activated-protein-kinase cascade
22. PKC-dependent modulation of IκB α-NFκB pathway in low metastatic B 16F1 murine melanoma cells and in highly metastatic BL6 cells
23. Protein kinase C-ε is responsible for the protection of preconditioning in rabbit cardiomyocytes
24. Evidence that translocation of protein kinase C is a key event during ischemic preconditioning of rabbit myocardium
25. An essential role of NFκB in tyrosine kinase signaling of p 38 MAP kinase regulation of myocardial adaptation to ischemia
26. A simple technique for the rescue of early region I mutations into infectious human adenovirus type 5
27. Preconditioning of isolated rat heart is mediated by protein kinase C
28. Ischemic preconditioning activates MAPKAPK2 in the isolated rabbit heart: Evidence for involvement of p 38 MAPK
29. Regulation of protein kinase C
30. PKC-dependent activation of p44/p42 MAPKs during myocardial ischemia-reperfusion in conscious rabbits
31. PKC-dependent activation of p46/p 54 JNKs during ischemic preconditioning in conscious rabbits
32. Ischemic preconditioning induces selective translocation of protein kinase C isoforms epsilon and eta in the heart of conscious rabbits without subcellular redistribution of total protein kinase C activity
33. Direct evidence that protein kinase C plays an essential role in the development of late preconditioning against myocardial stunning in conscious rabbits and that epsilon is the isoform involved
34. Increased protein synthesis is necessary for the development of late preconditioning against myocardial stunning
35. Protein kinase C isoform expression and regulation in the developing rat heart
36. Activation of the mitogen-activated protein kinase/extracellular signal-regulated kinase pathway by conventional, novel, and atypical protein kinase C isotypes
37. Regulation of NF-κB activation by MAP kinase cascades
38. A high throughput system for the evaluation of protein kinase C inhibitors based on Elk 1 transcriptional activation in human astrocytoma cells
39. Novel roles of specific isoforms of protein kinase C in activation of the c-fos serum response element
40. ++-dependent signal transduction pathways
41. 'Stress-responsive' mitogen-activated protein kinases (c-Jun N-terminal kinases and p38 mitogen-activated protein kinases) in the myocardium
42. Biphasic regulation of transcription factor nuclear factor-κB activity in human endothelial cells by lysophosphatidylcholine through protein kinase C-mediated pathway
43. Homologous regulation of the gonadotropin-releasing hormone receptor gene is partially mediated by protein kinase C activation of an activator protein- 1 element
44. Transcription factor AP-1 regulation by mitogen-activated protein kinase signal transduction pathways
45. Protein kinase C-dependent activation of NF-κB in enterocytes is independent of IκB degradation
46. AP-I: One switch for many signals
47. 2-terminal kinase in oncogenic ras-induced morphologic transformation of human lung carcinoma cells
48. Nuclear factor-κB plays an essential role in the late phase of ischemic preconditioning in conscious rabbits
49. 2-terminal kinase activation, and defects in AP- 1 transcriptional activity
50. Immediate-early gene induction and MAP kinase activation during recovery from metabolic inhibition in cultured cardiac myocytes
51. 2-terminal kinase/stress-activated protein kinase through domains distinct from Wnt signaling
52. The expression of constitutively active isotypes of protein kinase C to investigate preconditioning
53. Mitogen-activated protein kinase/ERK kinase kinases 2 and 3 activate nuclear factor-κB through IκB kinase-α and IκB kinase-β